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List of works by Stanley B. Prusiner

2-Aminothiazoles as therapeutic leads for prion diseases

scientific article

2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease

scientific article published on 18 March 2013

A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells ⬇️

scientific article published on 3 April 2017

A Survey of Antiprion Compounds Reveals the Prevalence of Non-PrP Molecular Targets ⬇️

scientific article published on May 24, 2011

A change in the conformation of prions accompanies the emergence of a new prion strain.

scientific article

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform 1 1Edited by M. Yaniv ⬇️

scientific article published on October 31, 1997

A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling

scientific article

A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains

scholarly article

A high-throughput screening assay for determining cellular levels of total tau protein

scientific article

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

scientific article published in November 1997

A long-lived Aβ oligomer resistant to fibrillization

scientific article published on 10 January 2018

A microangiopathic syndrome of encephalopathy, hearing loss, and retinal arteriolar occlusions

scientific article published in August 1985

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination

scientific article

A national strategy for development of effective methods for the prevention and treatment of Alzheimer's disease and related neurodegenerative disorders

scientific article

A novel vector for transgenesis in the rat CNS.

scientific article published on 21 November 2017

A prion protein variant in a family with the telencephalic form of Gerstmann-Straussler-Scheinker syndrome ⬇️

scientific article published on May 1, 1991

A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice

scientific article

A protease-resistant protein is a structural component of the scrapie prion

scientific article published in November 1983

A rapid radioactive assay for glutamine synthetase, glutaminase, asparagine synthetase, and asparaginase ⬇️

scientific article published on 01 October 1970

A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice

scientific article published on January 2000

A transmembrane form of the prion protein in neurodegenerative disease

scientific article

AIDS virus and scrapie protein genes

scientific article

Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene

scientific article

Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice

scientific article published in August 1996

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

scientific article published on November 1993

Abnormal plasma membrane properties and functions in prion-infected cell lines

scientific article published on January 1, 1996

Acceleration of scrapie in neonatal Syrian hamsters

scientific article published in October 1989

Acceleration of scrapie in trisomy 16----diploid aggregation chimeras

scientific article

Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation

scientific article

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

scientific article

Affinity-tagged miniprion derivatives spontaneously adopt protease-resistant conformations

scientific article

Amyloid plaques in Creutzfeldt-Jakob disease stain with prion protein antibodies

scientific article published in August 1986

Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58 ⬇️

scientific article published on March 1, 1991

An approach to the isolation of biological particles using sedimentation analysis ⬇️

scientific article published on February 10, 1978

Analysis of nucleic acids in purified scrapie prion preparations

scientific article published on 01 January 1993

Analysis of proteome dynamics in the mouse brain

scientific article

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

scientific article published in August 2001

Antibodies to a scrapie prion protein

scientific article published in August 1984

Antibodies to the scrapie protein decorate prion rods.

scientific article published in July 1985

Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change

scientific article

Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells.

scientific article

Assembly of natural and recombinant prion protein into fibrils

scientific article published in June 2005

Asymptomatic deer excrete infectious prions in faeces

scientific article

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

scientific article (publication date: October 1999)

Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems ⬇️

scientific article published on October 1, 1992

Attempts to restore scrapie prion infectivity after exposure to protein denaturants

scientific article

Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain

scientific article published on 01 May 2019

Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice

scientific article published on 21 August 2013

Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

scientific article

Bioassays and Inactivation of Prions

scientific article

Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]

scientific article published on February 1987

Biohazards of Investigations on the Transmissible Spongiform Encephalopathies ⬇️

scientific article published on September 1, 1980

Biology and genetics of prion diseases

scientific article published on January 1994

Biology and genetics of prions causing neurodegeneration

scientific article

Biology and structure of scrapie prions

scientific article published on January 1986

Biology of prion diseases

scientific article

Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease ⬇️

scientific article published on January 24, 2011

Biosynthesis of the prion proteins in scrapie-infected cells in culture

scientific article published in February 1994

Bitemporal hypometabolism in Creutzfeldt-Jakob disease measured by positron emission tomography with [18F]-2-fluorodeoxyglucose

scientific article published in October 1984

Brain tissue from persons dying of Creutzfeldt-Jakob disease causes scrapie-like encephalopathy in goats

scientific article published on 01 December 1980

Branched polyamines cure prion-infected neuroblastoma cells

scientific article

CNS amyloid proteins in neurodegenerative diseases

scientific article published in October 1988

COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

scientific article

Cell biology. A unifying role for prions in neurodegenerative diseases

scientific article published on June 2012

Cell division modulates prion accumulation in cultured cells

scholarly article

Changes in neuropeptide expression in mice infected with prions

scientific article

Changes in the localization of brain prion proteins during scrapie infection

scientific article published in January 1998

Changes in the localization of brain prion proteins during scrapie infection

scientific article published in August 1987

Characterization of cloned cDNA representing rat myelin basic protein: Absence of expression in brain of shiverer mutant mice ⬇️

scientific article published on October 1, 1983

Characterization of prion proteins with monospecific antisera to synthetic peptides

scientific article

Chemical chaperones interfere with the formation of scrapie prion protein

scientific article published in December 1996

Chemical induction of misfolded prion protein conformers in cell culture.

scientific article

Chemistry and biology of prions

scientific article published on December 15, 1992

Chimeric elk/mouse prion proteins in transgenic mice ⬇️

scientific article published on October 24, 2012

Chimeric prion protein expression in cultured cells and transgenic mice

scientific article

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

scientific article published in April 1995

Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein

scientific article published on July 1996

Citations must default to the online publication date

journal article; published in Nature on 2018-06-27

Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons

scientific article

Colloid formation by drugs in simulated intestinal fluid

scientific article

Comparative studies on membranes from bovine choroid plexus and rat kidney cortex ⬇️

scientific article published on September 15, 1977

Compartment Modeling for Mammalian Protein Turnover Studies by Stable Isotope Metabolic Labeling ⬇️

scientific article published on April 19, 2012

Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

scientific article published on December 1999

Complete Genomic Sequence and Analysis of the Prion Protein Gene Region from Three Mammalian Species ⬇️

scientific article published on October 1, 1998

Complete penetrance of Creutzfeldt-Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein gene

scientific article

Conformation of PrP(C) on the cell surface as probed by antibodies

scientific article published in February 2003

Conformation-dependent high-affinity monoclonal antibodies to prion proteins

scientific article

Conformational Transformation and Selection of Synthetic Prion Strains ⬇️

scientific article published on August 4, 2011

Conformational propagation with prion-like characteristics in a simple model of protein folding

scientific article published on April 2001

Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

scientific article published in July 1995

Conservation of the cellular gene encoding the scrapie prion protein

scientific article

Conserved properties of human and bovine prion strains on transmission to guinea pigs ⬇️

scientific article published on July 4, 2011

Continuous quinacrine treatment results in the formation of drug-resistant prions

scientific article published in November 2009

Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.

scholarly article

Control of metabolism in brown adipose tissue ⬇️

scientific article published on 01 January 1970

Convergent Replication of Mouse Synthetic Prion Strains ⬇️

scientific article published on March 1, 2013

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

scientific article

Cooperative binding of dominant-negative prion protein to kringle domains

scientific article

Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry

scientific article

Copper binding to the prion protein: structural implications of four identical cooperative binding sites

scientific article

Copper coordination in the full-length, recombinant prion protein

scientific article published on June 2003

Copper induces conformational changes in the N-terminal part of cell-surface PrPC.

scientific article published on 22 June 2006

Copper-catalyzed oxidation of the recombinant SHa(29-231) prion protein

scientific article

Creutzfeldt-Jakob disease and scrapie prions

scientific article

Creutzfeldt-Jakob disease prion proteins in human brains

scientific article

Cryo-immunogold electron microscopy for prions: toward identification of a conversion site

scientific article

Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH.

scientific article

Culture and Characterization of Epithelial Cells from Bovine Choroid Plexus ⬇️

scientific article published on October 1, 1981

Cultured cell sublines highly susceptible to prion infection

scientific article published on May 2000

Cytosolic prion protein in neurons.

scientific article published in August 2003

DNA length polymorphism 5? to the myelin basic protein gene is associated with multiple sclerosis ⬇️

scientific article published on March 1, 1990

DNA length polymorphism located 5' to the human myelin basic protein gene.

scientific article

De novo generation of prion strains ⬇️

scientific article published on September 26, 2011

Decreased MK-801 binding in discrete hippocampal regions of prion-infected mice

scientific article published in August 2001

Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release

scientific article published on September 1996

Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins

scientific article published in January 1994

Degradation of Fungal Prion HET-s(218-289) Induces Formation of a Generic Amyloid Fold ⬇️

scientific article published on May 15, 2012

Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse

scientific article published on April 1993

Design and construction of diverse mammalian prion strains

scientific article

Detecting mad cow disease.

scientific article published in July 2004

Detecting prion protein gene mutations by denaturing gradient gel electrophoresis

scientific article published in January 1994

Determinants of carboxyl-terminal domain translocation during prion protein biogenesis.

scientific article

Determination of scrapie agent titer from incubation period measurements in hamsters

scientific article published on 01 January 1981

Developing Therapeutics for PrP Prion Diseases

scientific article published on 17 January 2017

Development of antibody fragments for immunotherapy of prion diseases

scientific article published in March 2009

Developmental expression of PrP in the post-implantation embryo

scientific article published on 23 December 2006

Developmental expression of prion protein gene in brain

scientific article published in May 1987

Developmental regulation of prion protein mRNA in brain.

scientific article published in January 1988

Diagnosis of human prion disease

scientific article

Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation

scientific article published in February 2002

Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains

scientific article

Differential inhibition of prion propagation by enantiomers of quinacrine

scientific article

Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C.

scientific article published in June 1990

Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation

scientific article published on 21 July 2006

Discovering DNA encodes heredity and prions are infectious proteins

scientific article published in January 2006

Discovering the cause of AIDS

historical essay; Science, Volume 298, Issue 5599

Discovery and Preliminary Structure–Activity Relationship of Arylpiperazines as Novel, Brain-Penetrant Antiprion Compounds ⬇️

scientific article published on April 11, 2013

Discovery of 2-aminothiazoles as potent antiprion compounds

scientific article

Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity

scientific article published on 30 January 2020

Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds

scientific article published on April 2007

Disorders of glutamate metabolism and neurological dysfunction

scientific article published on January 1981

Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity

scientific article published in March 1996

Distinct prion proteins in short and long scrapie incubation period mice

scientific article published in November 1987

Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

scientific article

Diversity of oligosaccharide structures linked to asparagines of the scrapie prion protein

scientific article published on 01 October 1989

Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein

scientific article

Dominant-negative inhibition of prion replication in transgenic mice

scientific article

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

scientific article published in September 2000

Doppel-induced cerebellar degeneration in transgenic mice ⬇️

scientific article published on December 4, 2001

Doxycycline control of prion protein transgene expression modulates prion disease in mice ⬇️

scientific article published on October 13, 1998

Drug resistance confounding prion therapeutics

scientific article published on 15 October 2013

Early evidence that a protease-resistant protein is an active component of the infectious prion.

scientific article

Eight prion strains have PrPSc molecules with different conformations ⬇️

scientific article (publication date: October 1998)

Electron crystallography of the scrapie prion protein complexed with heavy metals

scientific article published on 23 August 2007

Electrophoretic properties of the scrapie agent in agarose gels

scientific article

Electrospray mass spectrometry of the glycosylinositol phospholipid of the scrapie prion protein ⬇️

scientific article published on September 1, 1991

Elimination of prions by branched polyamines and implications for therapeutics

scientific article

Energetic disturbance of cation transport as a cause of intracellular brain edema ⬇️

scientific article published on 01 January 1970

Engineering the prion protein using chemical synthesis

scientific article published in November 2001

Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system ⬇️

scientific article published on November 15, 1991

Erratum to: Generation of antisera to purified prions in lipid rafts.

scientific article published in July 2011

Erratum: Asymptomatic deer excrete infectious prions in faeces

scientific article published in Nature

Etiology and pathogenesis of prion diseases.

scientific article published on April 1995

Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge ⬇️

scientific article published on November 1, 1979

Evidence for a secretory form of the cellular prion protein.

scientific article

Evidence for assembly of prions with left-handed beta-helices into trimers

scholarly article

Evidence for hydrophobic domains on the surface of the scrapie agent

scientific article published on January 1, 1978

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation ⬇️

scientific article published on September 16, 1997

Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice

scientific article published on 4 December 2017

Evidence for synthesis of scrapie prion proteins in the endocytic pathway

scientific article published on August 1992

Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

scientific article published in December 1996

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

scientific article

Evidence that bank vole PrP is a universal acceptor for prions

scientific article (publication date: April 2014)

Expanding spectrum of prion diseases

scientific article published on 17 August 2020

Experimental Models of Inherited PrP Prion Diseases

scientific article published on 17 January 2017

Experimental scrapie in mice: Ultrastructural observations ⬇️

scientific article published on September 1, 1978

Experimental scrapie in the mouse: electrophoretic and sedimentation properties of the partially purified agent

scientific article

Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster

scientific article published in June 1995

Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.

scientific article

Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains

scientific article published on October 2000

Failure to transmit disease from gray tremor mutant mice.

scientific article published in March 1997

Familial Creutzfeldt-Jakob Disease: Codon 200 Prion Disease in Libyan Jews ⬇️

scientific article published on July 1, 1997

Familial Parkinson's point mutation abolishes multiple system atrophy prion replication

scientific article published on 26 December 2017

Folding of prion protein to its native alpha-helical conformation is under kinetic control

scientific article

Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.

scientific article published in August 1987

FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice

scientific article published on 11 July 2016

Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis

scientific article published on 01 April 1992

Further purification and characterization of scrapie prions

scientific article published in December 1982

Gel electrophoresis and glass permeation chromatography of the hamster scrapie agent after enzymatic digestion and detergent extraction

scientific article published on 01 October 1980

Generation of antisera to purified prions in lipid rafts

scientific article

Genes contributing to prion pathogenesis

scientific article

Genetic and infectious prion diseases

scientific article published on November 1993

Genetic control of prion incubation period in mice.

scientific article published on January 1988

Genetic control of scrapie and Creutzfeldt-Jakob disease in mice

scientific article published on 01 July 1983

Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time

scientific article published on December 1988

Genetics of prion diseases and prion diversity in mice

scientific article published on March 1994

Genetics of prion infections

scientific article

Genetics of prions ⬇️

scientific article published on January 1, 1997

Glycosylation differences between the normal and pathogenic prion protein isoforms

scientific article

Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid

scientific article published on June 2, 1992

Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions

scientific article published on 20 July 2016

H2 histamine receptors on the epithelial cells of choroid plexus

scientific article published in February 1986

Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an α-helix ⬇️

scientific article published on July 1, 1997

High-level expression and characterization of a purified 142-residue polypeptide of the prion protein

scientific article

Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie

scientific article published on April 1994

Hormones and Neurotransmitters Control Cyclic AMP Metabolism in Choroid Plexus Epithelial Cells ⬇️

scientific article published on 01 February 1984

Human prion diseases

scientific article published on 01 April 1994

Human prion diseases and neurodegeneration

scientific article published on January 1996

Human prion strain selection in transgenic mice

scientific article

Human prions and plasma lipoproteins

scholarly article

Huntington disease phenocopy is a familial prion disease

scientific article

Identification of I137M and Other Mutations That Modulate Incubation Periods for Two Human Prion Strains ⬇️

scientific article published on March 21, 2012

Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice ⬇️

scientific article published on December 23, 1997

Identification of a protein that purifies with the scrapie prion

scientific article published in December 1982

Identification of candidate proteins binding to prion protein

scientific journal article

Identification of cellular proteins binding to the scrapie prion protein

scientific article published in June 1990

Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein

scientific article

Identification of prion amyloid filaments in scrapie-infected brain

scientific article published in May 1985

Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy

scientific article published on November 2000

Identification of two prion protein regions that modify scrapie incubation time

scientific article

Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form

scientific article

Immuno-gold localization of prion filaments in scrapie-infected hamster brains

scientific article published in December 1987

Immunoaffinity purification and neutralization of scrapie prion infectivity

scientific article

Immunoaffinity purification and neutralization of scrapie prions

scientific article

Immunoblotting of Creutzfeldt-Jakob disease prion proteins: host species-specific epitopes

scientific article published on 01 June 1987

Immunoglobulins in urine of hamsters with scrapie

scientific article published on 12 August 2004

Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie

scientific article published on November 1990

Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy

scientific article published on March 1993

Immunological studies of scrapie infection ⬇️

scientific article published on 01 November 1982

Inactivation of prions by acidic sodium dodecyl sulfate

scientific article

Induction of distinct [URE3] yeast prion strains

scientific article

Infectious and genetic manifestations of prion diseases

scientific article published on May 1991

Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation

scientific article published on 18 September 2007

Inherited human prion diseases

scientific article published on December 1990

Inherited prion disease caused by the V210I mutation: transmission to transgenic mice.

scientific article

Inherited prion diseases

scientific article

Insertion in prion protein gene in familial Creutzfeldt-Jakob disease

scientific article published in The Lancet

Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease

scientific article published on January 1996

Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice

scientific article published in July 1996

Intracellular accumulation of the cellular prion protein after mutagenesis of its Asn-linked glycosylation sites

scientific article published on September 1990

Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice

scientific article

Is Parkinson's disease a prion disorder?

scientific article published on 28 July 2009

Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR

scientific article published on 01 May 1997

Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines

scientific article

Kinetics of d-glucose transport into renal membrane vesicles: Measurement using a vacuum manifold apparatus ⬇️

scientific article published on 01 March 1981

Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie

scientific article published on December 1999

Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy

scientific article published on 04 February 2020

Kuru with incubation periods exceeding two decades

scientific article published in July 1982

Link between scrapie and BSE?

scientific article published in July 1990

Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome

scientific article published in March 1989

Linkage of prion protein and scrapie incubation time genes

scientific article published on 01 August 1986

Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene

scientific article published on April 1, 1992

Lipid composition in scrapie-infected mouse brain: prion infection increases the levels of dolichyl phosphate and ubiquinone

scientific article published on 01 January 1996

Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics

scientific article published in March 2001

Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?

scientific article published in October 2002

MSA prions exhibit remarkable stability and resistance to inactivation

scientific article published on 28 August 2017

Mapping the Prion Protein Using Recombinant Antibodies ⬇️

scientific article published on November 1, 1998

Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease ⬇️

scientific article published on November 25, 1997

Measurement of the scrapie agent using an incubation time interval assay

scientific article

Measuring prions by bioluminescence imaging

scientific article published on 17 August 2009

Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

scientific article

Mechanism of scrapie prion precipitation with phosphotungstate anions

scientific article published on 19 February 2015

Mechanisms of prion protein assembly into amyloid

scholarly article

Membrane Populations of Bovine Choroid Plexus: Separation by Density Gradient Centrifugation in Modified Colloidal Silica ⬇️

scientific article published on 01 September 1981

Metabolic control in isolated brown fat cells

scientific article published in February 1970

Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus

scientific article published on March 1996

Mimicking dominant negative inhibition of prion replication through structure-based drug design

scientific article published on May 2000

Mitogen Stimulation of Splenocytes from Mice Infected with Scrapie Agent ⬇️

scientific article published on 01 September 1978

Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation

scientific article

Modulation of gamma-glutamyl transpeptidase activity from bovine choroid plexus ⬇️

scientific article published on June 1, 1978

Molecular biology and genetics of neurodegenerative diseases caused by prions

scientific article

Molecular biology and genetics of prion diseases

scientific article published on March 1994

Molecular biology and genetics of prion diseases.

scientific article published on January 1996

Molecular biology and genetics of prions--implications for sheep scrapie, "mad cows" and the BSE epidemic. Historical background

scientific article published in April 1991

Molecular biology and pathogenesis of prion diseases

scientific article

Molecular biology and pathology of scrapie and the prion diseases of humans

scientific article

Molecular biology and transgenetics of prion diseases

scientific article published on January 1991

Molecular biology of prion diseases

scientific article

Molecular biology of prions causing infectious and genetic encephalopathies of humans as well as scrapie of sheep and BSE of cattle

scientific article published on January 1, 1991

Molecular characteristics of prion rods purified from scrapie-infected hamster brains

scientific article published on July 1986

Molecular characteristics of the major scrapie prion protein

scientific article published in December 1984

Molecular cloning of a candidate chicken prion protein ⬇️

scientific article published on October 1, 1992

Molecular cloning of a human prion protein cDNA

scientific article

Molecular cloning of a mink prion protein gene

scientific article published in October 1992

Molecular genetics and biophysics of prions.

scientific article

Molecular genetics and transgenic model of Gertsmann-Sträussler-Scheinker disease

scientific article published on January 1991

Molecular properties of complexes formed between the prion protein and synthetic peptides ⬇️

scientific article published on July 25, 1997

Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent

scientific article published in October 1980

Molecular structure, biology, and genetics of prions

scientific article published on January 1988

Molecular studies of prion diseases

scientific journal article

Monoclonal antibodies to the cellular and scrapie prion proteins

scientific article published on 01 September 1986

Mouse models for studying the formation and propagation of prions

scientific article

Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines

scientific article published on 28 January 2019

Mutant PrPSc conformers induced by a synthetic peptide and several prion strains

scientific article published on February 2004

Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles

scientific article published on April 1, 1992

Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD).

scientific article

Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease

scientific article published on March 1994

Mutation of the prion protein gene at codon 208 in familial Creutzfeldt-Jakob disease

scientific article published on November 1996

Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease

scientific article published on April 1991

N-terminally tagged prion protein supports prion propagation in transgenic mice

scientific article

Natural and experimental prion diseases of humans and animals

scientific article published on October 1, 1992

Natural and synthetic prion structure from X-ray fiber diffraction

scientific article published on 28 September 2009

Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

scientific article

Nerve growth factor induces gene expression of the prion protein and beta-amyloid protein precursor in the developing hamster central nervous system

scientific article published in January 1990

Neurodegeneration in humans caused by prions

scientific article

Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system

scientific article published on 01 May 1998

Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein.

scientific article published in February 1990

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

scientific article published on April 16, 1992

Notch-1 activation and dendritic atrophy in prion disease

scientific article

Novel Properties and Biology of Scrapie Prions ⬇️

scientific article published on January 1, 1991

Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells

scientific article

Novel epitopes identified by anti-PrP monoclonal antibodies produced following immunization of Prnp0/0 Balb/cJ mice with purified scrapie prions

scientific article

Novel mechanisms of degeneration of the central nervous system--prion structure and biology.

scientific article published on January 1988

Novel proteinaceous infectious particles cause scrapie

scientific article (publication date: 9 April 1982)

Novel structure and genetics of prions causing neurodegeneration in humans and animals

scientific article published on October 1990

Nucleic acids in prion preparations: unspecific background or essential component?

scientific article published on 01 March 1994

On safari with PrP: prion diseases of animals

scientific article published in April 1995

On the biology of prions

scientific article

On the regulation of glutaminase in E. coli: metabolite control

scientific article published on 01 December 1971

Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice

scientific article published on 17 June 2016

Oxidation of methionine residues in the prion protein by hydrogen peroxide

scientific article published in December 2004

Oxidative Metabolism in Cells Isolated from Brown Adipose Tissue. 2. Catecholamine Regulated Respiratory Control ⬇️

scientific article published on 01 December 1968

Oxidative metabolism in cells isolated from brown adipose tissue. 1. Catecholamine and fatty acid stimulation of respiration

scientific article published on 01 October 1968

Partial purification and evidence for multiple molecular forms of the scrapie agent ⬇️

scientific article published on November 14, 1978

Partial purification and kinetics of gamma-glutamyl transpeptidase from bovine choroid plexus ⬇️

scientific article published on June 1, 1978

Pathologic conformations of prion proteins ⬇️

scientific article published on January 1, 1998

Pathway complexity of prion protein assembly into amyloid

scientific article published on 23 March 2002

Permethylation and tandem mass spectrometry of oligosaccharides having free hexosamine: analysis of the glycoinositol phospholipid anchor glycan from the scrapie prion protein

scientific article

Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment ⬇️

scientific article published on March 1, 2003

Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity

scientific article

Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice

scientific article published on 16 February 2013

Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter

scientific article

Pharmacokinetics of quinacrine in the treatment of prion disease

scientific article

Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells

scientific article published in March 2007

Physical studies of conformational plasticity in a recombinant prion protein

scientific article

Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo

scientific article published on June 2013

Polio and Nobel prizes: looking back 50 years

scientific article published in May 2007

Potent inhibition of scrapie prion replication in cultured cells by bis-acridines

scientific article

PrPSc in scrapie-infected hamster brain is spatially and temporally related to histopathology and infectivity titer

scientific article

Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid

scientific article

Predicted secondary structure and membrane topology of the scrapie prion protein

scientific article

Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease

scientific article published on July 1, 1992

Preservation by freezing of glucose and alanine transport into kidney membrane vesicles

scientific article published on 01 September 1978

Primary structure of prion protein may modify scrapie isolate properties

scientific article

Prion Diseases and the BSE Crisis ⬇️

scientific article published on October 10, 1997

Prion Protein Biology ⬇️

scientific article published on May 1, 1998

Prion Protein Genes: Evolutionary and Functional Aspects ⬇️

scientific article published on January 1, 1991

Prion Protein Isoforms, a Convergence of Biological and Structural Investigations ⬇️

scientific article published on August 18, 1995

Prion Protein Selectively Binds Copper(II) Ions ⬇️

scientific article published on May 19, 1998

Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering

scientific article

Prion and doppel proteins bind to granule cells of the cerebellum

scientific article

Prion biology and diseases--laughing cannibals, mad cows, and scientific heresy

scientific article published on September 1996

Prion biology and diseases.

scientific article published in January 1991

Prion biology: implications for Alzheimer's disease therapeutics

scientific article published on 16 September 2020

Prion clearance in bigenic mice

scientific article

Prion detection by an amyloid seeding assay.

scholarly article

Prion disease (PrP-A117V) presenting with ataxia instead of dementia

scientific article published in November 1995

Prion diseases and central nervous system degeneration.

scientific article

Prion diseases and neurodegeneration

scientific article

Prion diseases of the central nervous system

scientific article published on January 1990

Prion encephalopathies of animals and humans.

scientific article

Prion glycoprotein: structure, dynamics, and roles for the sugars

scientific article published in April 2001

Prion infection of mouse neurospheres

scholarly article

Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

scientific article published on June 1994

Prion liposomes

scientific article published on February 1990

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

scientific article

Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in zitter rats

scientific article published on January 1994

Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform

scientific article

Prion protein - mediator of toxicity in multiple proteinopathies

scientific article published on 01 April 2020

Prion protein amyloid: separation of scrapie infectivity from PrP polymers.

scientific article

Prion protein conformation in a patient with sporadic fatal insomnia

scientific article

Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system

scientific article published in December 1997

Prion protein gene expression in cultured cells.

scientific article published in April 1988

Prion protein gene variation among primates

scientific article

Prion protein gene variation among primates

scientific article published in January 1997

Prion protein mutation at codon 102 in an Italian family with Gerstmann-Sträussler-Scheinker syndrome

scientific article published on April 1, 1992

Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice

scientific article

Prion protein peptides induce alpha-helix to beta-sheet conformational transitions

scientific article published in April 1995

Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred

scientific article published on October 1992

Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations

scientific article published on January 1, 1996

Prion protein transgenes and the neuropathology in prion diseases

scientific article published on January 1995

Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease

scientific article published on June 2009

Prion proteins with pathogenic and protective mutations show similar structure and dynamics

scientific article published on September 2009

Prion uptake in the gut: identification of the first uptake and replication sites

scientific article (publication date: December 2011)

Prion-protein immunoreactivity in human transmissible dementias

scientific article published in November 1986

Prions

scientific article

Prions

scientific article published on 01 October 1984

Prions and neurodegenerative diseases

scientific article published on 01 December 1987

Prions and nucleic acids: search for "residual" nucleic acids and screening for mutations in the PrP-gene.

scientific article

Prions and prion proteins

scientific article published on October 1991

Prions are novel infectious pathogens causing scrapie and Creutzfeldt-Jakob disease

scientific article

Prions causing degenerative neurological diseases

scientific article

Prions causing nervous system degeneration

scientific article published on April 1987

Prions in skeletal muscle

scientific article

Prions--infectious pathogens causing the spongiform encephalopathies.

scientific article

Prions.

scientific article

Prions: Novel Infectious Pathogens

scientific article published on January 1, 1984

Prions: so many fibers, so little infectivity

scientific article published on April 2004

Progressive retinal degeneration in scrapie-infected hamsters: a light and electron microscopic analysis

scientific article published on 01 January 1981

Propagation of prion strains through specific conformers of the prion protein

scientific article published on December 1997

Propagation of prions causing synucleinopathies in cultured cells

scientific article

Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.

scientific article

Properties of scrapie prion protein liposomes ⬇️

scientific article published on April 5, 1988

Properties of scrapie prion proteins in liposomes and amyloid rods

scientific article published on January 1988

Proposed three-dimensional structure for the cellular prion protein

scientific article published on July 1994

Protease-Resistant Prions Selectively Decrease Shadoo Protein ⬇️

scientific article published on November 17, 2011

Protease-sensitive synthetic prions

scientific article

Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity ⬇️

scientific article published on September 1, 1991

Purification and properties of the cellular and scrapie hamster prion proteins

scientific article published in September 1988

Purification and properties of the cellular prion protein from Syrian hamster brain ⬇️

scientific article published on October 1, 1992

Purification and structural studies of a major scrapie prion protein

scientific article published in August 1984

Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions ⬇️

scientific article published on June 18, 2012

Purified prion proteins and scrapie infectivity copartition into liposomes

scientific article

Purified scrapie prions resist inactivation by UV irradiation

scientific article published on January 1987

Purified scrapie prions resist inactivation by procedures that hydrolyze, modify, or shear nucleic acids

scientific article

Pyridine nucleotide changes during thermogenesis in brown fat tissue in vivo

scientific article published on 01 February 1968

Quantitative trait loci affecting prion incubation time in mice

scientific article published on 01 October 2000

Quantitative traits of prion strains are enciphered in the conformation of the prion protein

scientific article published in January 2000

Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein

scientific article published on 31 March 2006

Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease

scientific article

Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation

scientific article

Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins

scientific article published in January 1990

Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro

scientific article

Recombinant scrapie-like prion protein of 106 amino acids is soluble

scientific article published on December 1996

Reflections on kuru

scientific article published in November 2008

Regional mapping of prion proteins in brain ⬇️

scientific article published on August 15, 1992

Relationship of Acidemia to Cerebral Edema ⬇️

scientific article published in December 1965

Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor ⬇️

scientific article published on August 1, 1993

Repetitive DNA (TGGA)n 5′ to the human myelin basic protein gene: A new form of oligonucleotide repetitive sequence showing length polymorphism ⬇️

scientific article published on January 1, 1990

Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters ⬇️

scientific article published on July 1, 1992

Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein

article

Replication of scrapie prions in hamster eyes precedes retinal degeneration

scientific article published in January 1986

Replication of the scrapie agent in hamster brain precedes neuronal vacuolation

scientific article published in September 1983

Research on scrapie

scientific article published on 01 August 1982

Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation

scientific article

Resistance of the scrapie agent to inactivation by psoralens

scientific article

Retinal degeneration in experimental Creutzfeldt-Jakob disease

scientific article published on 01 December 1983

Reversible chemical modification of the scrapie agent

scientific article

Salivary prions in sheep and deer ⬇️

scientific article published on January 1, 2012

Scanning for mutations in the human prion protein open reading frame by temporal temperature gradient gel electrophoresis

scientific article published on October 1995

Scrapie PrP 27-30 is a sialoglycoprotein

scientific article published on February 1985

Scrapie agent contains a hydrophobic protein ⬇️

scientific article published on November 1, 1981

Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants

scientific article published on February 1985

Scrapie and Creutzfeldt-Jakob disease prions

scientific article

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

scientific article published on August 1986

Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells

scientific article

Scrapie and cellular prion proteins share polypeptide epitopes

scientific article published in May 1986

Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein

scientific article published in August 1996

Scrapie infection diminishes spines and increases varicosities of dendrites in hamsters: a quantitative Golgi analysis

scientific article published on 01 July 1987

Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones

scientific article published on 01 November 1994

Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein

scientific article published on June 2000

Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da.

scientific article published on June 1988

Scrapie prion protein contains a phosphatidylinositol glycolipid

scientific article

Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells ⬇️

scientific article published on June 1, 1990

Scrapie prion proteins are synthesized in neurons

scientific article published in January 1986

Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis

scientific article published on March 1991

Scrapie prions

scientific article published on January 1989

Scrapie prions aggregate to form amyloid-like birefringent rods

scientific article

Scrapie prions alter receptor-mediated calcium responses in cultured cells

scientific article published on November 1993

Scrapie prions selectively modify the stress response in neuroblastoma cells

scientific article

Scrapie prions, brain amyloid, and senile dementia.

scientific article

Scrapie prions: a three-dimensional model of an infectious fragment

scientific article published in January 1995

Scrapie prions: a three-dimensional model of an infectious fragment

scientific article published in January 1996

Scrapie-associated particles in postsynaptic processes. Further ultrastructural studies

scientific article published on 01 May 1981

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

scientific article published on May 1988

Search for a prion-specific nucleic acid

scientific article

Search for a putative scrapie genome in purified prion fractions reveals a paucity of nucleic acids

scientific article published on 01 January 1991

Search for a scrapie-specific nucleic acid: a progress report.

scientific article published on January 1988

Sedimentation characteristics of the scrapie agent from murine spleen and brain ⬇️

scientific article published on November 14, 1978

Sedimentation properties of the scrapie agent ⬇️

scientific article published on October 1, 1977

Selective neuronal targeting in prion disease

scientific article published on December 1997

Selective neuronal vulnerability during experimental scrapie infection: insights from an ultrastructural investigation

scientific article published on August 2000

Selective precipitation of prions by polyoxometalate complexes.

scientific article published in October 2005

Self-assembly of recombinant prion protein of 106 residues

scientific article published on March 2000

Separation and properties of cellular and scrapie prion proteins

scientific article published on April 1986

Separation of membrane-bound .gamma.-glutamyl transpeptidase from brush border transport and enzyme activities ⬇️

scientific article published on May 27, 1980

Separation of scrapie prion infectivity from PrP amyloid polymers

scientific article

Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients

scientific article

Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein

scientific article published on September 1994

Shattuck lecture--neurodegenerative diseases and prions

scientific article (publication date: 17 May 2001)

Slow viruses: molecular properties of the agents causing scrapie in mice and hamsters

scientific article published on 01 January 1980

Small-molecule aggregates inhibit amyloid polymerization

scientific article published on 27 January 2008

Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L).

scientific article published on 26 October 2005

Solid-state NMR studies of the prion protein H1 fragment

scientific article

Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration

scientific article

Solution structure of Syrian hamster prion protein rPrP(90-231).

scientific article

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform ⬇️

scientific article published on September 16, 1997

Some Speculations about Prions, Amyloid, and Alzheimer's Disease ⬇️

scientific article published on March 8, 1984

Spontaneous Neurodegeneration in Transgenic Mice with Prion Protein Codon 101 Proline → Leucine Substitutiona ⬇️

scientific article published on January 1, 1991

Spontaneous generation of anchorless prions in transgenic mice

scientific article published on 12 December 2011

Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein ⬇️

scientific article published on February 13, 2012

Spontaneous neurodegeneration in transgenic mice with mutant prion protein

scientific article

Stain for glutaminase activity

scientific article published on 01 July 1973

Strain-specified characteristics of mouse synthetic prions

scientific article

Strain-specified relative conformational stability of the scrapie prion protein

scientific article

Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study

scientific article (publication date: 10 August 2016)

Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions

scientific article published on 01 July 2000

Structural clues to prion replication

scientific article

Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease

scientific article published on 8 January 2018

Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form

scientific article

Structural studies of the scrapie prion protein by electron crystallography

scientific article

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

scientific article published in March 1993

Structural studies of truncated forms of the prion protein PrP.

scientific article

Structure and polymorphism of the mouse prion protein gene

scientific article published on July 1994

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

scientific article

Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells

scientific article published on 24 July 2006

Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics

scientific article published on January 2007

Structures of prion proteins and conformational models for prion diseases

scientific article published in January 1996

Structure−Activity Relationship Study of Prion Inhibition by 2-Aminopyridine-3,5-dicarbonitrile-Based Compounds: Parallel Synthesis, Bioactivity, and in Vitro Pharmacokinetics

article published in 2007

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

scientific article published on December 1996

Sulfated glycosaminoglycans in amyloid plaques of prion diseases

scientific article published on January 1989

Suppression of polyclonal B cell activation in scrapie-infected C3H/HeJ mice ⬇️

scientific article published on June 1, 1978

Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein

scholarly article

Synthesis and trafficking of prion proteins in cultured cells ⬇️

scientific article published on August 1, 1992

Synthetic mammalian prions

scientific article

Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells

scientific article

The PrP-like protein Doppel binds copper

scientific journal article

The Priori Diseases ⬇️

scientific article published on 01 July 1998

The burden of proof in linking AIDS to scrapie

scientific article published in Nature

The neurochemistry of prion diseases

scientific article published on November 1993

The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system

scientific article

The neuropathological phenotype in transgenic mice expressing different prion protein constructs

scientific article published on March 1994

The peculiar nature of unfolding of the human prion protein

scientific article published on 6 February 2004

The prion diseases

scientific article published on 01 January 1995

The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein

scientific article published on March 2000

The prion folding problem.

scientific article published in February 1997

The regulation of oxidative metabolism of isolated brown fat cells

scientific article published in March 1968

The three-dimensional structure of prion protein: implications for prion disease ⬇️

scientific article published on August 1, 1998

Theoretical studies of sequence effects on the conformational properties of a fragment of the prion protein: implications for scrapie formation ⬇️

scientific article published on May 1, 1995

Thermodynamic Considerations of Mammalian Thermogenesis ⬇️

scientific article published in Nature

Thermodynamics of model prions and its implications for the problem of prion protein folding

scientific article published in February 1999

Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites

scientific article published on 9 February 2007

Thiocyanate and hydroxyl ions inactivate the scrapie agent

scientific article

Three hamster species with different scrapie incubation times and neuropathological features encode distinct prion proteins

scientific article published on March 1990

Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform

scientific article

Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues

scientific article

Toward Development of Assays for Scrapie-Specific Antibodies ⬇️

scientific article published on 01 January 1981

Towards Optimization of Arylamides As Novel, Potent, and Brain-Penetrant Antiprion Lead Compounds ⬇️

scientific article published on July 11, 2013

Towards authentic transgenic mouse models of heritable PrP prion diseases

scientific article published on 28 June 2016

Trafficking of prion proteins through a caveolae-mediated endosomal pathway

scientific article

Transgenetic investigations of prion diseases of humans and animals

scientific article published on February 1993

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

scientific article

Transgenetics and cell biology of prion diseases: investigations of PrPSc synthesis and diversity

scientific article

Transgenetics and gene targeting in studies of prion diseases

scientific article published on January 1996

Transgenetics and neuropathology of prion diseases.

scientific article published on January 1996

Transgenetics of prion diseases.

scientific article published on January 1996

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

scientific article

Transgenic models of prion disease.

scientific article

Transgenic mouse brains for the evaluation and quality control of BSE tests

scientific article published on 01 March 2007

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

scientific article

Transmission and detection of prions in feces

scientific article

Transmission barriers for bovine, ovine, and human prions in transgenic mice

scientific article

Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein

scientific article published in October 1994

Transmission of elk and deer prions to transgenic mice

scientific article

Transmission of multiple system atrophy prions to transgenic mice

scientific article

Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein

scientific article

Transmission of scrapie in hamsters

scientific article published in November 1985

Two different neurodegenerative diseases caused by proteins with similar structures

scientific article

Ultrastructural Studies of Prions ⬇️

scientific article published on January 1, 1991

Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells

scientific article published on December 1, 1991

Ultrastructural studies on scrapie prion protein crystals obtained from reverse micellar solutions

scientific article

Unraveling prion diseases through molecular genetics

scientific article published on June 1989

Unusual topogenic sequence directs prion protein biogenesis

scientific article

Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice

scientific article

Vacuum Manifold for Rapid Assay of Enzymes Using Radioactive Tracers and Ion Exchange Chromatography ⬇️

scientific article published on 01 April 1971

Vasoactive intestinal peptide stimulates cyclic AMP metabolism in choroid plexus epithelial cells

scientific article

Viroids and prions

scientific article

When sporadic disease is not sporadic: the potential for genetic etiology

scientific article

X-ray diffraction of scrapie prion rods and PrP peptides

scientific article published in September 1995

α-Synuclein: Multiple System Atrophy Prions

scientific article published on 17 February 2017

β-Amyloid Prions and the Pathobiology of Alzheimer's Disease

scientific article published on 13 February 2017

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