List of works by Stephen Holgate

'Every breath we take: the lifelong impact of air pollution' - a call for action.

scientific article published in February 2017

15-lipoxygenase immunoreactivity in normal and in asthmatic airways

scientific article published on 01 April 1995

3',5'-Cyclic adenosine monophosphate-dependent protein kinase of the rat serosal mast cell and its immunologic activation ⬇️

scientific article published on 01 May 1980

6,9-deepoxy-6,9-(phenylimino)-delta 6,8-Prostaglandin I1, (U-60,257) stimulates prostaglandin D2 and inhibits thromboxane B2 release from ionophore challenged human dispersed lung cells

scientific article published on November 1984

9 alpha,11 beta-prostaglandin F2, a novel metabolite of prostaglandin D2 is a potent contractile agonist of human and guinea pig airways

scientific article

A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status

scientific article published in January 2002

A brief history of asthma and its mechanisms to modern concepts of disease pathogenesis

scientific article published on 6 May 2010

A comment on "Scientometrics in a changing research landscape".

scientific article published on 20 January 2015

A comparison of RT-PCR, in-situ hybridisation and in-situ RT-PCR for the detection of rhinovirus infection in paraffin sections

scientific article published on 01 September 1997

A comparison of planar scintigraphy and SPECT measurement of total lung deposition of inhaled aerosol.

scientific article published in January 2003

A comparison of the effects of polyarginine and stimulated eosinophils on the responsiveness of the bovine isovolumic bronchial segment preparation

scientific article published on June 1993

A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies

scientific article published on January 2013

A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects

scientific article published on September 2007

A defective type 1 response to rhinovirus in atopic asthma.

scientific article published on April 2002

A double‐blind, placebo controlled study of the effect of the specific histamine H1‐receptor antagonist, terfenadine, in chronic severe asthma ⬇️

scientific article published on June 1, 1995

A longitudinal study of baseline FEV1 and bronchial responsiveness in patients with asthma ⬇️

scientific article published on January 1, 1992

A look at the pathogenesis of asthma: the need for a change in direction.

scientific article published on May 2010

A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood

scientific article published on 09 November 2019

A microRNA network dysregulated in asthma controls IL-6 production in bronchial epithelial cells

scientific article

A new era of targeting the ancient gatekeepers of the immune system: toll-like agonists in the treatment of allergic rhinitis and asthma

scientific article published on 21 May 2014

A new look at the pathogenesis of asthma

scientific article

A non-bronchoconstrictor, bacteriostatic preservative for nebuliser solutions

scientific article

A population survey of respiratory symptoms in the elderly

scientific article published in March 1991

A randomised controlled study of the effectiveness of breathing retraining exercises taught by a physiotherapist either by instructional DVD or in face-to-face sessions in the management of asthma in adults

scientific article

A randomized, double-blind, placebo-controlled study of tumor necrosis factor-α blockade in severe persistent asthma

scientific article published on 08 January 2009

A scientific basis to the treatment of allergic diseases.

scientific article

A self management plan in the treatment of adult asthma

scientific article

A single-nucleotide polymorphism in intelectin 1 is associated with increased asthma risk

article

A treatment for allergic rhinitis: a view on the role of levocetirizine

scientific article

ADAM 33 and its association with airway remodeling and hyperresponsiveness in asthma

scientific article

ADAM 33: just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness?

scientific article published in June 2003

ADAM metallopeptidase domain 33 (ADAM33): identification and role in airways disease

scientific article published on July 2010

ADAM33 expression in asthmatic airways and human embryonic lungs

scientific article

ADAM33 polymorphism: association with bronchial hyper-responsiveness in Korean asthmatics

scientific article published in June 2004

ADAM33: a newly identified gene in the pathogenesis of asthma

scientific article published on November 2005

ADAM33: a newly identified protease involved in airway remodelling

scientific article

ADAM33: a novel therapeutic target for asthma

scientific article

Absence of a late-phase response or increase in histamine responsiveness after bronchial provocation with adenosine 5'-monophosphate in atopic and non-atopic asthma

scientific article

Absence of respiratory effects with ivabradine in patients with asthma

scientific article published on 13 March 2008

Activation of eosinophils with cytokines produced by lung mast cells

scientific article published on 01 October 1997

Activation of human mast cells after immunoglobulin E-dependent and neuropeptide stimulation

scientific article published on January 1989

Active sensitization of guinea-pig airways in vivo enhances in vivo and in vitro responsiveness.

scientific article published in October 1988

Acute and chronic inflammatory mechanisms in asthma

scientific article published on September 1995

Acute and chronic pharmacokinetics of asymmetrical doses of slow release choline theophyllinate in asthma

scientific article

Acute effect of inhaled bradykinin on tracheobronchial clearance in normal humans ⬇️

scientific article published on November 1, 1992

Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers

scientific article (publication date: March 1999)

Adamalysins in biology and disease

scientific article

Adenosine A2B receptors: a novel therapeutic target in asthma?

scientific article published in April 1998

Adenosine antagonism as an alternative mechanism of action of methylxanthines in asthma.

scientific article

Adenosine as a bronchoconstrictor mediator in asthma and its antagonism by methylxanthines

scientific article published on 01 September 1984

Adenosine as a pro-inflammatory mediator in asthma

scientific article published on January 1989

Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma?

scientific article published on October 1997

Adenosine in asthmatic lung.

scientific article published on January 1988

Adenosine inhibits and potentiates IgE-dependent histamine release from human basophils by an A2-receptor mediated mechanism ⬇️

scientific article published on December 1, 1983

Adenosine inhibits and potentiates IgE-dependent histamine release from human lung mast cells by an A2-purinoceptor mediated mechanism ⬇️

scientific article published on 01 December 1984

Adenosine provocation: a new test for allergic type airway inflammation

scientific article published in February 2002

Adenosine receptors as promising therapeutic targets for drug development in chronic airway inflammation

scientific article published on June 2006

Adenosine signalling in airways

scientific article

Adenosine-induced bronchoconstriction and its inhibition by nedocromil sodium

scientific article published on July 1993

Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline.

scientific article

Adenosine-induced bronchoconstriction in asthma: role of mast cell-mediator release

scientific article published on 01 February 1985

Adenosine: a key effector molecule of asthma or just another mediator?

scientific article published in February 2002

Adenosine: a positive modulator of airway inflammation in asthma

scientific article published on January 1991

Adhesion molecules and relationship to leukocyte levels in allergic eye disease

scientific article published on February 1998

Adhesion molecules and their role in inflammation

scientific article published on March 1, 1991

Adverse reactions to the non-drug constituents of nebuliser solutions

scientific article published in March 1988

Age specific trends in asthma mortality in England and Wales, 1983-95: results of an observational study

scientific article

Air pollution and health

scientific article (publication date: 19 October 2002)

Air pollution and lung health: An epilogue

article

Air pollution--a wicked problem.

scientific article published on 14 June 2017

Air pollution: The time has arrived for the medical profession to take ownership of the problem and act

scientific article published on 10 September 2019

Airway and metabolic resistance to intravenous salbutamol: a study in normal man

scientific article published on 01 September 1980

Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma

scientific article published on 01 November 1986

Airway endothelin levels in asthma: influence of endobronchial allergen challenge and maintenance corticosteroid therapy

scientific article published on 01 May 1997

Airway endothelin levels in asthma: influence of endobronchial hypertonic saline challenge

scientific article published on 01 February 1999

Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation

scientific article

Airway inflammation and atopic asthma: a comparative bronchoscopic investigation

scientific article published on January 1991

Airway inflammation and remodeling in asthma: current concepts

scientific article

Airway refractoriness to adenosine 5'-monophosphate after repeated inhalation

scientific article published on 01 January 1989

Airway remodeling in asthma: new insights

scientific article

Airway remodelling in asthma and novel therapy

scientific article published on March 2013

Airway response to exercise and methacholine in children with respiratory symptoms

scientific article published on May 1991

Albuterol and nedocromil sodium affect airway and leukocyte responses to allergen

scientific article published in June 1993

Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma

scientific article published on May 2003

Allergen activates peripheral blood eosinophil nuclear factor-kappaB to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin-8.

scientific article published in July 2004

Allergen-induced release of GM-CSF and IL-8 in vitro by nasal polyp tissue from atopic subjects prolongs eosinophil survival

scientific article published on 01 July 1997

Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus

scientific article published on 5 July 2017

Allergic diseases and asthma: a major global health concern

scientific article published on 01 February 2012

Allergic eye disease mechanisms

scientific article published in October 1998

Allergic inflammation and its pharmacological modulation in asthma

scientific article published on January 1991

Allergy and cot death: with special focus on allergic sensitivity to cows' milk and anaphylaxis

scientific article published on July 1990

Allergy or inflammation? From neuropeptide stimulation of human skin mast cells to studies on the mechanism of the late asthmatic response

scientific article published on January 1989

Allergy testing in respiratory medicine

scientific article published on October 1996

Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma

scientific article

Altered airway surfactant phospholipid composition and reduced lung function in asthma

scientific article published on 01 October 2000

Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium

scientific article published in June 2005

Amplified rhinovirus colds in atopic subjects

scientific article published on 01 May 1994

An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma

scientific article published on 27 February 2016

Analysis of Ig VH region genes encoding IgE antibodies in splenic B lymphocytes of a patient with asthma

scientific article published on May 1995

Analysis of novel disease-related genes in bronchial asthma

scientific article published in September 2002

Anaphylactic- and calcium-dependent generation of prostaglandin D2 (PGD2), thromboxane B2, and other cyclooxygenase products of arachidonic acid by dispersed human lung cells and relationship to histamine release ⬇️

scientific article published on 01 October 1984

Animal models of asthma: value, limitations and opportunities for alternative approaches

scientific article published on 23 June 2011

Anti-IgE antibody for the treatment of allergic asthma

scientific article published on 01 March 2001

Anti-IgE in Persistent Severe Allergic Asthma

Anti-IgE treatment: an update

scientific article

Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy

scientific article

Anti-inflammatory strategies for the treatment of asthma

scientific article published on March 21, 1992

Anticholinergics in acute bronchial asthma

scientific article published on January 1987

Antihistamines in asthma

scientific article

Antihistamines: back to the future. Preface

scientific article

Antihistamines: back to the future. Summary of the conclusions. BSACI. British Society for Allergy and Clinical Immunology

scientific article

Antileukotriene therapy. Future directions

scientific article

Antioxidant consumption and repletion kinetics in nasal lavage fluid following exposure of healthy human volunteers to ozone

scientific article published on 01 June 1999

Antioxidant kinetics in lung lavage fluid following exposure of humans to nitrogen dioxide

Application of functional genomics to study of inflammatory airways disease

scientific article

Are long-acting beta2-agonists safe in the treatment of asthma?

scientific article published on 01 September 2008

Are marine environmental pollutants influencing global patterns of human disease?

scientific article published on 29 October 2012

Aspirin exacerbated respiratory disease

scientific article

Assessment and treatment of obstructive airways disease in the elderly

scientific article

Assessment of deposition of inhaled aerosol in the respiratory tract of man using three-dimensional multimodality imaging and mathematical modeling.

scientific article published in January 1996

Association analysis of brain-derived neurotrophic factor gene polymorphisms in asthmatic families

scientific article published on 17 March 2009

Association between - 308 tumour necrosis factor promoter polymorphism and bronchial hyperreactivity in asthma

scientific article published on 01 September 1999

Association of asthma with a functional promoter polymorphism in the IL16 gene

scientific article published on January 2006

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

scientific article (publication date: 25 July 2002)

Association of the Gln 27 β2-Adrenoceptor Polymorphism and IgE Variability in Asthmatic Families

scientific article published in June 1997

Association of tumor necrosis factor-alpha polymorphisms and ozone-induced change in lung function

scientific article published on 14 October 2004

Associations between respiratory symptoms, bronchial response to methacholine, and atopy in two age groups of schoolchildren

scientific article published on August 1989

Astemizole and other H1-antihistaminic drug treatment of asthma

scientific article published on 01 August 1985

Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels ⬇️

scientific article published on July 1, 1984

Asthma

scientific article published on 10 September 2015

Asthma and allergy--disorders of civilization?

scientific article published in March 1998

Asthma control or severity: that is the question

scientific article published on February 2007

Asthma diagnosis: addressing the challenges

scientific article

Asthma genetics and personalised medicine

scientific article published on 2 May 2014

Asthma in the elderly: what we know and what we have yet to know

scientific article

Asthma mechanisms, determinants of severity and treatment: the role of nedocromil sodium Report of a workshop held in Whistler, British Columbia, Canada, 18–19 May 1995 ⬇️

scientific article published on August 1, 1995

Asthma out of control? A structured review of recent patient surveys

scientific article

Asthma survey items as predictors of respiratory problems in children 2 yrs later: a longitudinal study

scientific article published on 01 September 1999

Asthma. The mast cell

scientific article

Asthma: A Dynamic Disease of Inflammation and Repair ⬇️

scientific article published on January 1, 1997

Asthma: a simple concept but in reality a complex disease

scientific article published on 26 May 2011

Asthma: early predisposing factors

scientific article published on January 1997

Asthma: more than an inflammatory disease

scientific article published on 01 February 2002

Asthma: the importance of epithelial mesenchymal communication in pathogenesis. Inflammation and the airway epithelium in asthma

scientific article

Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

scientific article

Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis.

scientific article published in August 2002

Atopy phenotype

scientific article published in February 1998

Attenuation of exercise induced asthma by local hyperthermia

scientific article

Augmentation of permeability in the bronchial epithelium by the house dust mite allergen Der p1 ⬇️

scientific article published on 01 April 1995

Authors' reply

Autocrine ligands for the epidermal growth factor receptor mediate interleukin-8 release from bronchial epithelial cells in response to cigarette smoke

scientific article published in July 2002

Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles

scientific article published on 20 February 2014

BENZALKONIUM CHLORIDE AND BRONCHOCONSTRICTION

scientific article published in The Lancet

Bacterial contamination of home nebuliser

scientific article

Barrier disrupting effects of alternaria alternata extract on bronchial epithelium from asthmatic donors

scientific article

Barrier responses of human bronchial epithelial cells to grass pollen exposure.

scientific article

Basement membrane pores in human bronchial epithelium: a conduit for infiltrating cells?

scientific article published on February 2001

Basic fibroblast growth factor in asthma: measurement in bronchoalveolar lavage fluid basally and following allergen challenge

scientific article

Beta-catenin/T-cell factor-mediated transcription is modulated by cell density in human bronchial epithelial cells

scientific article

Biochemical maturation of the guinea pig lung and survival following premature delivery

scientific article published in January 1991

Biomarker Profiles in Asthma With High vs Low Airway Reversibility and Poor Disease Control

scientific article

Bloodspot cortisol in mild asthma: the effect of inhaled corticosteroids

scientific article

Bronchial angiogenesis in severe glucocorticoid-dependent asthma

scientific article published on 01 June 2000

Bronchial biopsy evidence for leukocyte infiltration and upregulation of leukocyte-endothelial cell adhesion molecules 6 hours after local allergen challenge of sensitized asthmatic airways

scientific article

Bronchial epithelial shedding in asthmatics and non-asthmatics

scientific article

Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma

scientific article

Bronchial hyperresponsiveness and its relationship to asthma in childhood

scientific article

Bronchial mucosal manifestations of atopy: a comparison of markers of inflammation between atopic asthmatics, atopic nonasthmatics and healthy controls

scientific article published on 01 May 1992

Bronchial mucosal mast cells and their implications in the pathogenesis of asthma

scientific article published on January 1986

Bronchial reactivity to histamine and bradykinin is unchanged after rhinovirus infection in normal subjects ⬇️

scientific article published on 01 March 1992

Bronchoconstriction induced by ipratropium bromide in asthma: relation to hypotonicity

scientific article published in August 1984

Bronchoconstriction induced by nebulised ipratropium bromide: relation to the bromide ion

scientific article published on December 1986

Bronchoconstrictor and antibronchoconstrictor properties of inhaled prostacyclin in asthma

Bronchoconstrictor properties of preservatives in ipratropium bromide (Atrovent) nebuliser solution

scientific article

Bronchodilator actions of xanthine derivatives administered by inhalation in asthma

scientific article

CAM research and development

scientific article

CD48 on blood leukocytes and in serum of asthma patients varies with severity.

scientific article

Candidate gene and mutational analysis in asthma and atopy

scientific article published on February 1999

Candidate gene loci in asthmatic and allergic inflammation

scientific article published on January 1996

Candidate loci and random marker approaches to studying the genetics of asthma.

scientific article published on January 1996

Candidate locus approach for studying the genetics of asthma and atopy

scientific article published on 01 June 1997

Case-control study of salmeterol and near-fatal attacks of asthma

scientific article

Cell adhesion molecules and the bronchial epithelium

scientific article

Cellular and biochemical events in the pathogenesis of asthma

scientific article published on January 1986

Cellular and chemical mediators--their roles in allergic diseases

scientific article published on April 1989

Cellular and mediator responses twenty-four hours after local endobronchial allergen challenge of asthmatic airways

scientific article published on 01 July 1996

Cellular changes 24 hours after endobronchial allergen challenge in asthma

scientific article published on 01 May 1995

Cellular localization of interleukin 13 receptor alpha2 in human primary bronchial epithelial cells and fibroblasts.

scientific article

Challenges and approaches for the development of safer immunomodulatory biologics

scientific article published on April 2013

Changes in sputum counts and airway hyperresponsiveness after budesonide: monitoring anti-inflammatory response on the basis of surrogate markers of airway inflammation

scientific article published in December 2002

Changing attitudes to exercise induced asthma.

scientific article published on December 1983

Chapter 1: Genetic and Environmental Influences

scientific article published on 01 November 2000

Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation

scientific article

Characterization of wheezing phenotypes in the first 10 years of life

scientific article published in May 2003

Chest physiotherapy

Chronic fatigue syndrome: understanding a complex illness.

scientific article

Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development

scientific article

Cigarette smoke causes caspase-independent apoptosis of bronchial epithelial cells from asthmatic donors

scientific article

Ciliated cell damage in the bronchial epithelium of asthmatics and non-asthmatics.

scientific article published in March 1993

Circulating histamine and eosinophil cationic protein levels in nocturnal asthma

scientific article

Clinical evaluation of nedocromil sodium in asthma.

scientific article

Clinical pharmacology of asthma. Implications for treatment

scientific article

Clonally related IgE and IgG4 transcripts in blood lymphocytes of patients with asthma reveal differing patterns of somatic mutation

scientific article published on October 1998

Cohabiting with domestic mites

scientific article published in January 1993

Comparative airway response to inhaled bradykinin, kallidin, and [des-Arg9]bradykinin in normal and asthmatic subjects

scientific article published in December 1990

Comparative nasal effects of bradykinin and histamine: influence on nasal airways resistance and plasma protein exudation

scientific article

Comparative nasal effects of bradykinin, kallidin and [Des-Arg9]-bradykinin in atopic rhinitic and normal volunteers.

scientific article published in June 1991

Comparative protective effect of the inhaled beta 2-agonist salbutamol (albuterol) on bronchoconstriction provoked by histamine, methacholine, and adenosine 5'-monophosphate in asthma

scientific article published in April 1990

Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever

scientific article

Comparative vascular effects of histamine, prostaglandin (PG) D2 and its metabolite 9alpha, 11beta-PGF2 in human skin

scientific article published on 01 November 1988

Comparison of 3' and 5' biotin labelled oligonucleotides for in situ hybridisation

scientific article published on 01 November 1993

Comparison of the effect of loratadine on the airway and skin responses to histamine, methacholine, and allergen in subjects with asthma

scientific article published on 1 December 1990

Comparison of the efficacy of preservative free ipratropium bromide and Atrovent nebuliser solution

scientific article

Comparison of the prevalence of asthma among Asian and European children in Southampton

scientific article

Compromised concentrations of ascorbate in fluid lining the respiratory tract in human subjects after exposure to ozone

scientific article published on July 1999

Concentration Response Functions for Ultrafine Particles and All-Cause Mortalilty and Hospital Admissions: Results of an European Expert Panel Elicitation

Concentration response functions for ultrafine particles and all-cause mortality and hospital admissions: results of a European expert panel elicitation

scientific article

Consensus Group on New-Generation Antihistamines (CONGA): present status and recommendations

scientific article

Considerations on third generation antihistamines

scientific article

Contribution of bronchial fibroblasts to the antiviral response in asthma.

scientific article published in March 2009

Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma

scientific article published on April 1990

Control of mediator release from mast cells ⬇️

scientific article published on October 1, 1982

Controlled-release theophylline in the treatment of nocturnal asthma

scientific article published in July 1990

Cooperative effects of Th2 cytokines and allergen on normal and asthmatic bronchial epithelial cells

scientific article

Corticosteroids and beta adrenergic agonists innormal subjects

scientific article published on January 1, 1977

Corticosteroids inhibit rhinovirus-induced intercellular adhesion molecule-1 up-regulation and promoter activation on respiratory epithelial cells

scientific article

Could the airway epithelium play an important role in mucosal immunoglobulin A production?

scientific article

Cross refractoriness between bradykinin and hypertonic saline challenges in asthma

scientific article published on 01 October 1995

Cross-tachyphylactic airway response to inhaled bradykinin, kallidin and [desArg9]-bradykinin in asthmatic subjects

scientific article published on 01 May 1993

Crystal-ball gazing--the future of immunological research viewed from the cutting edge

scientific article published on January 2007

Cultured nasal polyps from nonatopic and atopic patients release RANTES spontaneously and after stimulation with phytohemagglutinin ⬇️

scientific article

Current and future asthma therapies.

scientific article

Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis: disease mechanisms, a diagnostic test and specific treatments

scientific article

Cyclo-oxygenase

scientific article published in August 1998

Cyclosporin A treatment and airways inflammation in corticosteroid-dependent asthma

scientific article published on 01 January 1998

Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblasts

scientific article published on 07 November 2006

Cytokine and anti-cytokine therapy for the treatment of asthma and allergic disease

scientific article

Cytokine production by human mast cells.

scientific article

Cytokine profiles of BAL T cells and T-cell clones obtained from human asthmatic airways after local allergen challenge

scientific article published on 01 October 1999

Cytokines and airway inflammation

scientific article published on May 1994

Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction

scientific article published on August 2009

DNA-binding antibodies and hepatitis B markers in acute and chronic liver disease ⬇️

scientific article published on August 1, 1978

Davos declaration: allergy as a global problem

scientific article published in February 2012

Deep inspiration increases the absorption of inhaled sodium cromoglycate

scientific article

Defective epithelial barrier function in asthma.

scientific article

Dendritic cells in normal and asthmatic airways: expression of the alpha subunit of the high affinity immunoglobulin E receptor (FcepsilonRI-alpha)

article by J. M. TUNON-DE-LARA et al published June 1996 in Clinical & Experimental Allergy

Density profile of bronchoalveolar lavage eosinophils in the guinea pig model of allergen-induced late-phase allergic responses

scientific article published on March 1, 1992

Descriptive study of cough, wheeze and school absence in childhood

scientific article

Detection of respiratory syncytial virus infection in nasal aspirate samples by flow cytometry

scientific article published in August 1994

Detection of rhinovirus infection of the nasal mucosa by oligonucleotide in situ hybridization

scientific article

Determinants of asthma severity

scientific article published on 01 May 1995

Developing consensus on national respiratory research priorities: Key findings from the UK Respiratory Research Collaborative's e-Delphi exercise

scientific article

Dexamethasone treatment fails to reduce oxygen-induced lung injury in the preterm guinea pig. Effects on pulmonary inflammation and antioxidant status

scientific article

Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium

scientific article published on 6 May 2008

Differences in the asthma treatment of children between europe and Japan: a questionnaire-based survey using model cases

scientific article published on April 2009

Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel

scientific article published in January 2004

Differential inhibitory effect of regular inhaled corticosteroid on airway responsiveness to adenosine 5′ monophosphate, methacholine, and bradykinin in symptomatic children with recurrent wheeze ⬇️

scientific article published on 01 June 1997

Differential roles of IL-16 and CD28/B7 costimulation in the generation of T-lymphocyte chemotactic activity in the bronchial mucosa of mild and moderate asthmatic individuals.

scientific article published in December 2002

Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respira

scientific article

Disabling inflammatory pathways with biologics and resulting clinical outcomes in severe asthma

scientific article published on 07 January 2013

Discovery of new treatments in the context of delivering personalized medicine

scientific article published on 01 March 2012

Discussion session I: Pathophysiology in relation to treatment objectives

Dispersion and characterisation of mast cells from human skin

scientific article published on 01 January 1986

Distribution and determinants of personal exposure to nitrogen dioxide in school children

scientific article

Distribution of basement membrane pores in bronchus revealed by microscopy following epithelial removal

scientific article published on September 2002

Do skin prick and conjunctival provocation tests predict symptom severity in seasonal allergic rhinoconjunctivitis?

scientific article published on 01 December 2006

Document de consensus WAO–ARIA–GA2LEN sur le diagnostic allergologique moléculaire

Does baseline airway caliber affect measurements of airway responsiveness to histamine

scientific article published on 01 June 1993

Does dietary intake of vitamins C and E influence lung function in older people?

scientific article published in November 1996

Does inhaled PAF cause airway hyperresponsiveness in humans?

scientific article published on 01 September 1990

Does non-specific bronchial responsiveness indicate the severity of asthma?

scientific article published on February 1990

Does outdoor air pollution induce new cases of asthma? Biological plausibility and evidence; a review

scientific article published on August 2012

Dose-related antagonism of leukotriene D4-induced bronchoconstriction by p.o. administration of LY-171883 in nonasthmatic subjects ⬇️

scientific article published on August 1, 1988

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma

scientific article published in July 2010

Driving asthma care in Europe: the Brussels Declaration

scientific article published on 01 June 2009

Drug development for airway diseases: looking forward

scientific article published on 22 May 2015

Duration of growth suppressive effects of regular inhaled corticosteroids

scientific article published in February 1998

Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study

scientific article published on 29 May 2008

Early and late-phase bronchoconstriction after allergen challenge of nonanesthetized guinea pigs. I. The association of disordered airway physiology to leukocyte infiltration

scientific article published in March 1988

Early changes in T lymphocytes recovered by bronchoalveolar lavage after local allergen challenge of asthmatic airways

scientific article published on June 1, 1992

Early life risk factors for adult asthma: a birth cohort study of subjects at risk

scientific article published on November 2001

Editorial

scientific article published on 30 April 2020

Effect of GR32191, a potent thromboxane receptor antagonist, on exercise induced bronchoconstriction in asthma ⬇️

scientific article published on March 1, 1991

Effect of IL-13 receptor alpha2 levels on the biological activity of IL-13 variant R110Q.

scientific article

Effect of IVL745, a VLA-4 antagonist, on allergen-induced bronchoconstriction in patients with asthma

scientific article

Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction

scientific article published on 01 April 1989

Effect of an inhaled mast cell stabiliser, N-acetyl-aspartyl-glutamate (Zy15109) on allergen-induced immediate bronchoconstriction

scientific article

Effect of azelastine and ketotifen on the bronchial and skin responses to platelet-activating factor in humans ⬇️

scientific article published on 01 July 1991

Effect of bronchoconstriction on airway remodeling in asthma

scientific article published on 01 May 2011

Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells

scientific article published in August 2001

Effect of inhaled 15-(s)-hydroxyeicosatetraenoic acid on tracheobronchial clearance in normal human airways ⬇️

scientific article published on June 1, 1991

Effect of inhaled bradykinin on indices of airway responsiveness in asthmatic subjects

scientific article published on 01 August 1994

Effect of inhaled corticosteroids on episodes of wheezing associated with viral infection in school age children: randomised double blind placebo controlled trial

scientific article

Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma

scientific article published in July 2003

Effect of inhaled frusemide on responses of airways to bradykinin and adenosine 5'-monophosphate in asthma

scientific article published on May 1994

Effect of inhaled piriprost (U-60, 257) a novel leukotriene inhibitor, on allergen and exercise induced bronchoconstriction in asthma

scientific article

Effect of inhaled platelet-activating factor on bronchial inflammation in atopic non-asthmatic subjects

scientific article published in January 1992

Effect of methacholine induced bronchoconstriction on the pulmonary distribution and plasma pharmacokinetics of inhaled sodium cromoglycate in subjects with normal and hyperreactive airways

scientific article

Effect of mite allergen on permeability of bronchial mucosa

scientific article published on 01 November 1990

Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms.

scientific article

Effect of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine 5'-monophosphate

scientific article published in March 1989

Effect of nedocromil sodium on early and late phase responses to allergen challenge in the guinea-pig

scientific article published on 01 January 1989

Effect of omalizumab on lung function and eosinophil levels in adolescents with moderate-to-severe allergic asthma

scientific article published on 22 November 2019

Effect of omalizumab on peripheral blood eosinophilia in allergic asthma.

scientific article published on 20 October 2009

Effect of oral terfenadine on the bronchoconstrictor response to inhaled histamine and adenosine 5'-monophosphate in non-atopic asthma

scientific article

Effect of selective phosphodiesterase 3 inhibition on the early and late asthmatic responses to inhaled allergen

scientific article published on April 1998

Effect of thromboxane A2-receptor antagonist on bradykinin-induced bronchoconstriction in asthma

scientific article published on 01 June 1996

Effects of 0.2 ppm ozone on biomarkers of inflammation in bronchoalveolar lavage fluid and bronchial mucosa of healthy subjects

scientific article published in June 1998

Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man.

scientific article published on December 1987

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

scientific article published in December 2000

Effects of budesonide and formoterol on NF-kappaB, adhesion molecules, and cytokines in asthma

scientific article

Effects of high dose intravenous immunoglobulin in two severe corticosteroid insensitive asthmatic patients.

scientific article published on July 1997

Effects of indomethacin on cyclic nucleotide levels and histamine release from rat serosal mast cells ⬇️

scientific article published on October 1, 1979

Effects of inhaled 9 alpha, 11 beta-prostaglandin F2 on airway function in man.

scientific article

Effects of omalizumab on markers of inflammation in patients with allergic asthma

scientific article

Effects of ozone on epithelium and sensory nerves in the bronchial mucosa of healthy humans

scientific article published on September 1997

Effects of prostaglandin D2 and theophylline on rat serosal mast cells: discordance between increased cellular levels of cyclic AMP and activation of cyclic AMP-dependent protein kinase ⬇️

scientific article published on 01 October 1981

Effects of prostaglandin D2 on rat serosal mast cells: discordance between immunologic mediator release and cyclic AMP levels ⬇️

scientific article published on 01 September 1980

Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response

scientific article published on 01 December 2000

Effects of short-term exposure to 0.2 ppm ozone on biomarkers of inflammation in sputum, exhaled nitric oxide, and lung function in subjects with mild atopic asthma

scientific article published on 01 March 2000

Effects of theophylline on inflammatory cells and cytokines in asthmatic subjects: a placebo-controlled parallel group study

scientific article published on 01 August 1996

Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma

scientific article

Efficacy and safety of a recombinant anti-immunoglobulin E antibody (omalizumab) in severe allergic asthma

scientific article published in April 2004

Efficacy and safety of etanercept in moderate-to-severe asthma: a randomised, controlled trial

scientific article published on 25 November 2010

Efficacy of Andolast in Mild to Moderate Asthma: A Randomized, Controlled, Double-Blind Multicenter Study (The Andast Trial)

scientific article published on 01 January 2015

Efficacy of omalizumab, an anti-immunoglobulin E antibody, in patients with allergic asthma at high risk of serious asthma-related morbidity and mortality.

scientific article published in January 2001

Endothelin immunoreactivity of airway epithelium in asthmatic patients

scientific article published on 01 March 1991

Endothelin in bronchoalveolar lavage fluid and its relation to airflow obstruction in asthma ⬇️

scientific article published on 01 April 1995

Enhanced upregulation of smooth muscle related transcripts by TGF beta2 in asthmatic (myo) fibroblasts

scientific article

Environmental risk factors and allergic bronchial asthma

scientific article

Enzyme potentiated desensitisation in treatment of seasonal allergic rhinitis: double blind randomised controlled study

scientific article

Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells

scientific article published on 21 April 2008

Epithelial damage and response

scientific article

Epithelial repair is inhibited by an alpha(1,6)-fucose binding lectin

scientific article published on 6 October 2006

Epithelial stress and structural remodelling in childhood asthma

scientific article published on May 2005

Epithelial-mesenchymal communication in the pathogenesis of chronic asthma

scientific article

Epithelial-mesenchymal interactions in the pathogenesis of asthma

scientific article

Epithelially derived endothelin and nitric oxide in asthma

scientific article published on May 1995

Epithelium dysfunction in asthma

scientific article published on December 2007

Erratum: asthma in the elderly: what we know and what we have yet to know.

scientific article published on 18 June 2014

Essential role for both CD80 and CD86 costimulation, but not CD40 interactions, in allergen-induced Th2 cytokine production from asthmatic bronchial tissue: role for alphabeta, but not gammadelta, T cells

article

Evaluating the long-term consequences of air pollution in early life: geographical correlations between coal consumption in 1951/1952 and current mortality in England and Wales.

scientific article

Evaluation of airway inflammation by endobronchial and transbronchial biopsy in nocturnal and nonnocturnal asthma

scientific article published on 01 March 1995

Evaluation of the accuracy and precision of lung aerosol deposition measurements from planar radionuclide imaging using simulation

scientific article published on 01 August 1998

Evidence against the formation of 13,14-dihydro-15-keto-prostaglandin F2 alpha following inhalation of prostaglandin D2 in man.

scientific article published on March 1986

Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination ⬇️

scientific article published on May 1, 1990

Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha

scientific article published on 01 May 1990

Evidence of association between interferon regulatory factor 5 gene polymorphisms and asthma

article

Evidence that neutrophils do not participate in the late-phase airway response provoked by ovalbumin inhalation in conscious, sensitized guinea pigs

scientific article published in March 1990

Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease

scientific article

Exacerbations: the asthma paradox

scientific article published on 01 October 2005

Exclusion from proximal 11q of a common gene with megaphenic effect on atopy

article

Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: Relevance of circulating basophils to measurements of plasma histamine ⬇️

scientific article published on March 1, 1984

Exercise, asthma, and mast cells

scientific article published on 01 April 1983

Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus.

scientific article published on 16 February 2011

Experimental models in asthma

scientific article

Experimental rhinovirus infection in volunteers

scientific article published on 01 November 1996

Expert elicitation on ultrafine particles: likelihood of health effects and causal pathways

scientific article

Exposure, uptake, distribution and toxicity of nanomaterials in humans.

scientific article published on February 2010

Expression of CD44 and integrins in bronchial mucosa of normal and mildly asthmatic subjects

article

Expression of CD44 isoforms is increased in the airway epithelium of asthmatic subjects

scientific article published on January 1997

Expression of c-erbB receptors and ligands in human bronchial mucosa

scientific article

Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects

scientific article published in January 2002

Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease.

scientific article published on 07 December 2006

Expression of the high affinity receptor for immunoglobulin E (IgE) by dendritic cells in normals and asthmatics

scientific article published on 01 January 1995

Factors associated with mortality after an asthma admission: a national United Kingdom database analysis

scientific article published on 25 April 2007

Factors determining bradykinin bronchial responsiveness and refractoriness in asthma

scientific article published on 01 July 1993

Fatal asthma attack during an inhalation challenge with ultrasonically nebulized distilled water.

scientific article published in June 1995

Fluoridation: Interpreting the Newcastle fluoride bioavailability study

scientific article published on October 2007

Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study.

scientific article published in March 2002

Frmd7 expression in developing mouse brain

scientific article published on 6 March 2009

From "blockbusters" to "biosimilars": an opportunity for patients, medical specialists and health care providers

scientific article published on 23 September 2012

Function of the airway epithelium in asthma

scientific article published on 22 March 2012

Functional characterization of a novel 3D model of the epithelial-mesenchymal trophic unit

scientific article published on 3 April 2017

Gas cooking and smoking habits and the risk of childhood and adolescent wheeze

scientific article published on 10 August 2005

Gene expression in peripheral blood mononuclear cells from patients with chronic fatigue syndrome

scientific article published in August 2005

Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis.

scientific article published in April 2008

Gene-environment interaction in chronic disease: a European Science Foundation Forward Look

scientific article published on December 2011

Genes for asthma on chromosome 11: an update

scientific article published in April 1998

Genetic analysis of IgE.

scientific article published on May 1996

Genetic analysis of atopy and asthma as quantitative traits and ordered polychotomies

article

Genetic and environmental influences on airway inflammation in asthma

scientific article published on May 1995

Genetic and environmental interaction in allergy and asthma

scientific article

Genetic association studies of interleukin-13 receptor alpha1 subunit gene polymorphisms in asthma and atopy.

scientific article published on 28 March 2007

Genetic common ground between allergic and autoimmune disease: The role of cytotoxic T-lymphocyte antigen 4

Genetic susceptibility to the respiratory effects of air pollution.

scientific article published on June 2008

Genetics

scientific article published in January 2004

Genetics of Asthma and Bronchial Hyperresponsiveness

article

Genetics of allergic disease

article

Glucocorticoids enhance IgE synthesis. Are we heading towards new paradigms?

scientific article published on 01 November 2000

Granulocyte recruitment by human mast cell tryptase

scientific article published on 01 May 1995

Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma

scientific article published on April 1999

H1-antihistamines in asthma.

scientific article

HLA genetics and allergic disease

scientific article published on August 1995

Has the time come to rethink the pathogenesis of asthma?

scientific article published on February 2010

Health effects of acute exposure to air pollution. Part I: Healthy and asthmatic subjects exposed to diesel exhaust.

scientific article

Health effects of acute exposure to air pollution. Part II: Healthy subjects exposed to concentrated ambient particles.

scientific article published in December 2003

Health impact and toxicological effects of nanomaterials in the lung

scientific article published on July 2012

Histamine and its antagonists in asthma

scientific article published on August 1989

Histamine secretion from human skin slices induced by anti-IgE and artificial secretagogues and the effects of sodium cromoglycate and salbutamol

scientific article published in July 1985

Histochemical Heterogeneity of Human Mast Cells: Disease-Related Differences in Mast Cell Subsets Recovered by Bronchoalveolar Lavage ⬇️

scientific article published on January 1, 1990

How do lymphocytes get into the asthmatic airways? Lymphocyte traffic into and within the lung in asthma

scientific article published on January 1998

Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4

scientific journal article

Human bronchial fibroblasts express the 5-lipoxygenase pathway

scientific article

Human leukocyte antigen genes and allergic disease.

scientific article published on January 1996

Human lung mast cells are enriched in the capacity to produce granulocyte-macrophage colony-stimulating factor in response to IgE-dependent stimulation

scientific article published on 01 February 1998

Human mast cell tryptase stimulates the release of an IL-8-dependent neutrophil chemotactic activity from human umbilical vein endothelial cells (HUVEC)

scientific article published on 01 July 2000

Human mast cells express stem cell factor

article

Human tissue models for a human disease: what are the barriers?

scientific article published on 28 January 2015

Humidification as an adjunct to chest physiotherapy in aiding tracheo-bronchial clearance in patients with bronchiectasis

scientific article published on 01 March 1992

Hypocapnia and asthma: a mechanism for breathing retraining?

scientific article

IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations

scientific article

IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts

scientific article

IL-4 increases type 2, but not type 1, cytokine production in CD8+ T cells from mild atopic asthmatics

scientific article

IL-4 receptor alpha is an important modulator of IL-4 and IL-13 receptor binding: implications for the development of therapeutic targets.

scientific article

Identification and Function of a Novel Candidate Gene for Asthma:ADAM 33

article

Identification of ATPAF1 as a novel candidate gene for asthma in children

scientific article

Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness

scientific article published on 3 September 2009

Identification of novel expressed sequences, up-regulated in the leucocytes of chronic fatigue syndrome patients

article

Identifying and prioritizing uncertainties: patient and clinician engagement in the identification of research questions

IgE-dependent activation of human lung mast cells is not associated with increased phospholipid methylation

scientific article

IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation

scientific article published in August 1986

Immune circuits in asthma

scientific article published on 29 April 2013

Immunogenetics of human IgE

scientific article published in December 1996

Immunogenetics of human IgE.

scientific article published on January 1996

Immunoglobulin E decapeptide-induced 5-hydroxytryptamine release from rat peritoneal mast cells. Comparison with corticotropin-(1–24)-peptide, polyarginine, polylysine and antigen ⬇️

scientific article published on September 15, 1981

Immunohistochemical analysis of adhesion molecules in airway biopsies

scientific article published on 01 January 2000

Immunohistochemical analysis of nasal biopsies during rhinovirus experimental colds.

scientific article published in October 1994

Immunohistochemical identification of mast cells in formaldehyde-fixed tissue using monoclonal antibodies specific for tryptase

scientific article published in October 1990

Immunolocalization of cytokines to mast cells in normal and allergic conjunctiva

scientific article published on November 1997

Immunopathology and human mast cell cytokines

scientific article

Immunopathology of fatal soybean dust-induced asthma

scientific article published on 01 January 1996

Immunoreactive endothelin in bronchial biopsy specimens: increased expression in asthma and modulation by corticosteroid therapy

scientific article published on 01 October 1997

Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial

scientific article (publication date: 2002)

Improving outcomes for asthma patients with allergic rhinitis: conclusions from the MetaForum conferences

scientific article

Improving outcomes for asthma patients with allergic rhinitis: the MetaForum conferences

scholarly article by Stephen T. Holgate & David Price published 2006 in BMC Pulmonary Medicine

Improving the management of atopic disease

scientific article

Increased CD44 expression in human bronchial epithelial repair after damage or plating at low cell densities

scientific article published on 01 June 2000

Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment

scientific article published on May 2001

Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium

scientific article published on January 2003

Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma

scientific article published on 22 October 2004

Increased levels of IL-4 in CD8+ T cells in atopic asthma

scientific article published on 01 September 1997

Increased sensitivity to the consequences of rhinoviral infection in atopic subjects

scientific article published on 01 March 1995

Indirect airway challenges

scientific article

Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy

scientific article

Induction of bronchial beta-adrenergic receptor resistance in normal man [proceedings] ⬇️

scientific article published on June 1, 1977

Induction of nitric oxide synthase in asthma

scientific article published on 01 December 1993

Induction of the epidermal growth factor receptor and its ligands in nasal epithelium by ozone

scientific article published in January 2004

Inflammatory Processes in Bronchial Asthma1

Inflammatory and structural changes in the airways of patients with asthma

scientific article

Inflammatory cells and their mediators in the pathogenesis of asthma

scientific article published on January 1988

Inflammatory cytokines can enhance CD44-mediated airway epithelial cell adhesion independently of CD44 expression

scientific article published on 8 August 2003

Inflammatory mechanisms underlying potentiation of effects of inhaled aeroallergens in response to nitrogen dioxide in allergic airways disease

scientific article published on 01 February 1999

Inflammatory mediators and cellular infiltration of the lungs in a guinea pig model of the late asthmatic reaction.

scientific article

Inflammatory processes and bronchial hyperresponsiveness

scientific article published on January 1991

Inflammatory processes in bronchial asthma

scientific article published on January 1989

Inhalation rate of sodium cromoglycate determines plasma pharmacokinetics and protection against AMP-induced bronchoconstriction in asthma

scientific article published on 01 December 1988

Inhaled PAF fails to induce airway hyperresponsiveness to methacholine in normal human subjects

scientific article

Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects ⬇️

scientific article published on February 1, 1983

Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. 1983.

scientific article published on December 2004

Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma

scientific article published on January 1994

Inhaled histamine increases the rate of absorption of sodium cromoglycate from the lung ⬇️

scientific article published on March 1, 1992

Inhaled lodoxamide tromethamine in the treatment of perennial asthma: a double-blind placebo-controlled study

scientific article published in July 1985

Inhaled loop diuretics and basal airway responsiveness in man: evidence of a role for cyclo-oxygenase products ⬇️

scientific article published on 01 April 1995

Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine

scientific article published in August 1989

Inhaled sodium cromoglycate

scientific article published on August 1996

Inhaled sodium cromoglycate in children with asthma

scientific article published in March 2002

Inhaled synthetic surfactant abolishes the early allergen-induced response in asthma

scientific article

Inhibition by nedocromil sodium of early and late phase bronchoconstriction and airway cellular infiltration provoked by ovalbumin inhalation in conscious sensitized guinea-pigs

scientific article published on May 1988

Inhibition of adenosine 5'-monophosphate- and methacholine-induced bronchoconstriction in asthma by inhaled frusemide

scientific article published on 01 June 1990

Inhibition of exercise-induced asthma by nifedipine: a dose-response study.

scientific article

Inhibition of histamine release from dispersed human lung and tonsillar mast cells by nicardipine and nifedipine

scientific article (publication date: May 1985)

Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma

scientific article published in June 2001

Innate and adaptive immune responses in asthma

scientific article published on 04 May 2012

Interaction of human mast cell tryptase with endothelial cells to stimulate inflammatory cell recruitment

scientific article published on 01 February 1999

Interaction of inhaled LTC4 with histamine and PGD2 on airway caliber in asthma

scientific article published in January 1989

Interaction of neuropeptides with human mast cells.

scientific article published on January 1989

Interactive effect of inhaled bradykinin with histamine and PGD2 in bronchial asthma

scientific article published on 01 November 1993

Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma

scientific article published in December 2003

Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines

scientific article

Interleukin-5 production by human airway epithelial cells

scientific article

Interpatient variability in rates of asthma progression: can genetics provide an answer?

scientific article published on March 2008

Intradermal challenge with interleukin-8 causes tissue oedema and neutrophil accumulation in atopic and non-atopic human subjects

Introduction: the anti-inflammatory role of cysteinyl leukotriene receptor antagonists in asthma

scientific article published in January 2003

Investigative use of fibreoptic bronchoscopy for local airway challenge in asthma

scientific article published on October 1993

Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma

scientific article

Involvement of the epidermal growth factor receptor in epithelial repair in asthma

scientific article published on July 2000

Ionophore-dependent generation of eicosanoids in human dispersed lung cells. Modulation by 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin I1 (U-60,257)

scientific article published on 01 June 1986

Is artificial fluoride absorbed to the same extent as natural fluoride?

scientific article published in January 2008

Is asthma due to partial beta-blockade of airways?

scientific article published on January 1, 1983

Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype?

scientific article

Is big beautiful? The continuing story of ADAM33 and asthma

scientific article published in April 2005

Is diesel exhaust a cause for increasing allergies?

scientific article published on 01 January 1999

Is electrodermal testing as effective as skin prick tests for diagnosing allergies? A double blind, randomised block design study

scientific article

Kinetic analysis of the interleukin-13 receptor complex

scientific article (publication date: 29 November 2002)

Kinins and rhinitis

scientific article published in August 1992

Lack of association of HLA class I genes and TNF alpha-308 polymorphism in toluene diisocyanate-induced asthma

scientific article published in January 2004

Lack of tachyphylaxis to histamine in both moderate and mild asthmatic subjects

scientific article published in April 1990

Laser Doppler flowmetry for determining changes in cutaneous blood flow following intradermal injection of histamine

Laser Doppler flowmetry for determining changes in cutaneous blood flow following intradermal injection of histamine.

scientific article

Lessons learnt from the epidemic of asthma

scientific article published in May 2004

Letter from the UK (if we still exist after recent events!): Air pollution: The public health challenge of our time ⬇️

scientific article

Letter: Intravenous prednisolone in asthma

scientific article

Leucocyte-endothelial adhesion molecules and their role in bronchial asthma and allergic rhinitis ⬇️

scientific article published on July 1, 1993

Leukocyte responses to experimental infection with human rhinovirus

scientific article published on 01 December 1994

Leukotriene C4 and histamine in early allergic reaction in the nose

scientific article published in April 1988

Leukotriene and prostanoid pathway enzymes in bronchial biopsies of seasonal allergic asthmatics

scientific article published in December 2001

Leukotriene antagonists and synthesis inhibitors: new directions in asthma therapy

scientific article

Leukotriene modifiers in the treatment of asthma. Look promising across the board of asthma severity

scientific article published on April 1998

Linkage analysis of the 5q31–33 candidate region for asthma in 240 UK families

article

Linkage of asthma to markers on chromosome 12 in a sample of 240 families using quantitative phenotype scores

scientific article

Linkage/association study of a locus modulating total serum IgE on chromosome 14q13-24 in families with asthma

scientific article published on October 2004

Local action on outdoor air pollution to improve public health

article

Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms.

scientific article published on April 2007

Localization of interleukin (IL) -4 but not IL-5 to human mast cell secretory granules by immunoelectron microscopy

scientific article published on 01 April 2000

Long-term effects of inhaled corticosteroids in asthmatic children

scientific article published on 01 March 2001

Longitudinal changes in skin-prick test reactivity over 2 years in a population of schoolchildren with respiratory symptoms

scientific article published on 01 October 1992

Low-dose methotrexate treatment in severe glucocorticoid-dependent asthma: effect on mucosal inflammation and in vitro sensitivity to glucocorticoids of mitogen-induced T-cell proliferation

scientific article published on 01 March 2000

Lower airways inflammation during rhinovirus colds in normal and in asthmatic subjects

scientific article published in March 1995

Lower airways inflammatory response during rhinovirus colds

scientific article published on 01 May 1995

Maintenance of skills, competencies, and performance in allergy and clinical immunology: time to lay the foundation for a universal approach

scientific article

Mast cell activation in asthma.

scientific article published on January 1989

Mast cell and histamine content of human bronchoalveolar lavage fluid

scientific article

Mast cell distribution and neutral protease expression in acute and chronic allergic conjunctivitis

scientific article published on 01 January 1995

Mast cell numbers and staining characteristics in the normal and allergic human conjunctiva ⬇️

scientific article published on January 1, 1991

Mast cell tryptase and histamine concentrations in bronchoalveolar lavage fluid from patients with interstitial lung disease ⬇️

scientific article published on 01 August 1991

Mast cell tryptase as a proinflamatory mediator in late-phase asthmatic response

scientific article published on 01 March 2002

Mast cell-dependent inflammatory mediators and their putative role in bronchial asthma

scientific article

Mast cells, mediators and asthma

scientific article published on May 1985

Mast-cell infiltration of airway smooth muscle in asthma.

scientific article published in May 2002

Matrix metalloproteinase-2 from bronchial epithelial cells induces the proliferation of subepithelial fibroblasts

scientific article published in June 2002

Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses

scientific article

Mechanisms and significance of adenosine-induced bronchoconstriction in asthma

scientific article published on October 1987

Mechanisms of airway epithelial damage: epithelial-mesenchymal interactions in the pathogenesis of asthma ⬇️

scientific article published on September 1, 2003

Mechanisms of airways inflammation which may be amenable to prophylaxis

scientific article

Mechanisms of asthma and implications for its prevention and treatment: a personal journey

scientific article published on 25 June 2013

Mechanisms of exercise-induced asthma

scientific article published on September 1994

Mechanisms of particulate matter toxicity

scientific article

Mechanisms of purine-induced bronchoconstriction in asthma

scientific article published on January 1990

Mechanisms of virus induced exacerbations of asthma

scientific article published on April 1997

Mechanisms of virus-induced asthma exacerbations: state-of-the-art. A GA2LEN and InterAirways document.

scientific article published on 27 February 2007

Mediator and cellular mechanisms in asthma. The Philip Ellman lecture 1990.

scientific article published in October 1990

Mediator and cytokine mechanisms in asthma

scientific article

Mediators of inflammation in response to air pollution: a focus on ozone and nitrogen dioxide

scientific article

Medium-term culture of normal human oral mucosa: a novel three-dimensional model to study the effectiveness of drugs administration

scientific article

Medium-term culture of primary oral squamous cell carcinoma in a three- dimensional model: effects on cell survival following topical 5-fluororacile delivery by drug-loaded matrix tablets

scientific article published on January 2012

Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization

scientific article

Methods for the assessment of endobronchial biopsies in clinical research: application to studies of pathogenesis and the effects of treatment

scientific article published on September 2003

Modulation of the chemotactic responsiveness of guinea pig neutrophils to hrIL-8 and fMLP.

scientific article published in December 1994

Molecular mediators of asthma: current insights

scientific article published on October 1996

Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial

scientific article

Montelukast or salmeterol combined with an inhaled steroid in adult asthma: design and rationale of a randomized, double-blind comparative study (the IMPACT Investigation of Montelukast as a Partner Agent for Complementary Therapy-trial).

scientific article published in June 2000

Mucosal IgA is an important moderator of eosinophil responses to tissue-derived chemoattractants

scientific article

Mucosal Inflammation and Asthma

scientific article published on 01 November 1994

Mucosal cytokine expression in allergic rhinitis

article

Mucosal inflammation in asthma

scientific article published on August 1990

Mucosal inflammation in severe glucocorticoid-dependent asthma

scientific article published on 01 June 1999

Mucosal nerves in endobronchial biopsies in asthma and non-asthma

scientific article published on 01 January 1991

Multiple cytokine mRNA expression in human mast cells stimulated via Fc epsilon RI

scientific article published on 01 May 1995

NF-kappa B and TNF-alpha: a positive autocrine loop in human lung mast cells?

scientific article published on 01 November 2002

Nasal Cavity Lining Fluid Ascorbic Acid Concentration Increases in Healthy Human Volunteers Following Short Term Exposure to Diesel Exhaust

Nasal effects of bradykinin and capsaicin: influence on plasma protein leakage and role of sensory neurons ⬇️

scientific article published on 01 April 1992

Natural history of asthma in childhood--a birth cohort study

scientific article published on September 1991

Nedocromil sodium blocks the early and late phases of allergen challenge in a guinea pig model of asthma

scientific article published on 01 July 1993

Nedocromil sodium is more potent than sodium cromoglycate against AMP-induced bronchoconstriction in atopic asthmatic subjects

scientific article published on 01 May 1989

Neuropeptide-containing nerves in endobronchial biopsies from asthmatic and nonasthmatic subjects.

scientific article published in September 1995

Neutrophil and eosinophil chemotaxins in asthma.

scientific article published on December 1993

Neutrophil influx and interleukin-8 release after segmental allergen or saline challenge in asthmatics

scientific article published on 01 May 1995

New Insights into Airway Inflammation by Endobronchial Biopsy

scientific article published on February 1, 1992

New perspectives on the putative role of eicosanoids in airway hyperresponsiveness

scientific article published on 01 August 1985

New strategies in the treatment and prevention of allergic diseases

scientific article published on February 2004

New strategies with anti-IgE in allergic diseases

scientific article published on 29 July 2014

New targets for allergic rhinitis--a disease of civilization

scientific article published on November 2003

Newer therapies for asthma: a focus on anti-IgE.

scientific article

Non-IgE-dependent bacteria-induced histamine release from human lung and tonsillar mast cells.

scientific article

Novel targets of therapy in asthma

scientific article published on January 2009

Omalizumab in asthma: an update on recent developments

scientific article published on 11 June 2014

Omalizumab, a novel anti-IgE therapy in allergic disorders

scientific article

On the generation of allergic airway diseases: from GM-CSF to Kyoto.

scientific article

Opposite effects of inhaled bradykinin and [desArg9]-bradykinin on tracheobronchial clearance in normal humans

scientific article published on 01 April 1996

Osteocalcin, growth, and inhaled corticosteroids: a prospective study

scientific article

Overcoming fragmentation of health research in Europe: lessons from COVID-19

scientific article published on 16 June 2020

Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma

scientific article

Oxidative stress in air pollution research

scientific article published on 30 April 2020

Oxidative transformations of arachidonic acid in human dispersed lung cells: disparity between the utilization of endogenous and exogenous substrate

scientific article published on October 1985

Ozone, airways and allergic airways disease

scientific article published on December 1995

Ozone-induced bronchial epithelial cytokine expression differs between healthy and asthmatic subjects.

scientific article published in June 2003

Ozone-induced lung function decrements do not correlate with early airway inflammatory or antioxidant responses

article

PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline

scientific article

Paradoxical bronchoconstriction in asthmatic patients after salmeterol by metered dose inhaler

scientific article

Pathogenesis of asthma

scientific article published on 01 June 2008

Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches?

scientific article published on 31 July 2011

Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood

scientific article (publication date: 2011)

Pattern of usage and somatic hypermutation in the V(H)5 gene segments of a patient with asthma: implications for IgE.

scientific article published on January 1997

Peak expiratory flow changes during experimental rhinovirus infection

scientific article published on 01 November 2000

Peak flow based asthma self-management: a randomised controlled study in general practice. British Thoracic Society Research Committee

scientific article published on August 1995

Penicillin allergy: how to diagnose and when to treat

scientific article published on April 1988

Peripheral blood CD4+ and CD8+ T cell type 1 and type 2 cytokine production in atopic asthmatic and normal subjects.

scientific article published in March 2002

Personal exposure to nitrogen dioxide (NO2) and the severity of virus-induced asthma in children

scientific article published in June 2003

Personal exposure to nitrogen dioxide and risk of airflow obstruction in asthmatic children with upper respiratory infection

scientific article

Personal exposures of children to nitrogen dioxide relative to concentrations in outdoor air.

scientific article

Perspective: A human touch

journal article; published in Nature on 2011-11-23

Pharmacogenetics: the new science of personalizing treatment

scientific article

Pharmacokinetics of andolast after administration of single escalating doses by inhalation in mild asthmatic patients

scientific article published in March 2001

Phenotypic analysis of airway eosinophils and lymphocytes in a Th-2-driven murine model of pulmonary inflammation.

scientific article published in July 1996

Phenotypic characterization of T cells infiltrating the conjunctiva in chronic allergic eye disease

scientific article published on September 1996

Phosphodiesterase and cyclic adenosine monophosphate-dependent inhibition of T-lymphocyte chemotaxis

scientific article published on 01 February 2000

Physiotherapy breathing retraining for asthma: a randomised controlled trial.

scientific article published on 13 December 2017

Plasma and urinary histamine in allergen-induced early and late phase asthmatic responses ⬇️

scientific article published on 01 September 1993

Polymorphism at the tumour necrosis factor locus and asthma.

scientific article published on January 1996

Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function

scientific article (publication date: July 2005)

Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population.

scientific article published in August 2003

Potential and novel therapies for asthma

scientific article

Predicting and evaluating response to omalizumab in patients with severe allergic asthma

scientific article published in July 2007

Predicting persistent disease among children who wheeze during early life ⬇️

scientific article published on November 1, 2003

Predicting response to omalizumab, an anti-IgE antibody, in patients with allergic asthma

scientific article

Prevalence of atopy and range of bronchial response to methacholine in 7 and 11 year old schoolchildren

scientific article published on August 1989

Prevalence of atopy in asthma

scientific article published on 01 July 1994

Prevalence of bronchial reactivity to inhaled methacholine in New Zealand children.

scientific article

Prevalence of respiratory symptoms among 7 and 11 year old schoolchildren and association with asthma

scientific article published on August 1989

Prevalence of untreated asthma in a population sample of 6000 older adults in Bristol, UK.

scientific article published on June 2001

Primary and secondary effector cells in the pathogenesis of bronchial asthma.

scientific article

Priorities for respiratory research in the UK.

scientific article published on January 2007

Production and characterization of monoclonal antibodies specific for human mast cell tryptase

scientific article published in September 1990

Production of IL-8 and IL-4 by positively and negatively selected CD4+ and CD8+ human T cells following a four-step cell separation method including magnetic cell sorting (MACS)

scientific article published on 01 January 1996

Profile of bronchial responsiveness in children with respiratory symptoms ⬇️

scientific article published on May 1, 1992

Profound overexpression of leukotriene C4 synthase in bronchial biopsies from aspirin-intolerant asthmatic patients

scientific article published on 01 May 1997

Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population

scientific article published on August 2003

Promoter polymorphism influences the effect of dexamethasone on transcriptional activation of the LTC4 synthase gene

scientific article published in August 2003

Prophylactic management of children at risk for recurrent upper respiratory infections: the Preventia I Study.

scientific article published on November 2004

Prostaglandin D2 release from human skin mast cells in response to ionophore A23187.

scientific article published on November 1987

Protection against allergen-induced asthma by salmeterol

scientific article published on 01 December 1990

Proteomics of bronchial biopsies: galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients

scientific article published on 3 September 2014

Pulmonary synthesis, release, and metabolism of prostaglandins

scientific article published on August 1985

RANTES: a novel mediator of allergic inflammation?

scientific article published on October 1994

Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma

scientific article

Reassessment of asthma management in an accident and emergency department

scientific article published in September 1991

Recent advances in understanding the pathogenesis of asthma and its clinical implications

scientific article published on January 1988

Recent developments in the pathogenesis and epidemiological trends of asthma.

scientific article

Red Cell Magnesium in a Population of House Dust Mite Sensitive Asthmatics

scholarly article by George T. Lewith et al published January 2000 in Journal of Nutritional and Environmental Medicine

Reduced selenium status of patients with asthma

scientific article published on 01 November 1989

Reducing agents inhibit rhinovirus-induced up-regulation of the rhinovirus receptor intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells

scientific article published on 4 October 2002

Reducing the hidden burden of severe asthma: recognition and referrals from primary practice

scientific article published on 29 April 2020

Reflections on the mechanism(s) of action of sodium cromoglycate (Intal) and the role of mast cells in asthma

scientific article

Regulation of a disintegrin and metalloprotease-33 expression by transforming growth factor-β.

scientific article

Regulatory and research needs

scientific article published on 01 February 2013

Relation between chest expansion, pulmonary function, and exercise tolerance in patients with ankylosing spondylitis

scientific article

Relation of the hypertonic saline responsiveness of the airways to exercise induced asthma symptom severity and to histamine or methacholine reactivity

scientific article

Relationship between mediator release from human lung mast cells in vitro and in vivo

scientific article published on January 1985

Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD.

scientific article published on October 2004

Relationship between skin-prick tests, the multiple allergosorbent test and symptoms of allergic disease

scientific article published on 01 January 1989

Relationships between adenosine, cyclic nucleotides, and xanthines in asthma

scientific article

Relative efficacy of oral verapamil and digoxin alone and in combination for the treatment of patients with chronic atrial fibrillation

scientific article published on 01 April 1988

Relative potencies and time course of changes in adenosine 5'-monophosphate airway responsiveness with inhaled furosemide and bumetanide in asthma

scientific article published on 01 August 1993

Release of adenosine and its metabolites from activated human leucocytes

scientific article published on 01 May 1986

Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways

scientific article

Repeated exposure of asthmatic airways to inhaled adenosine 5'-monophosphate attenuates bronchoconstriction provoked by exercise

scientific article published on 01 September 1990

Repeated inhalation of bradykinin attenuates adenosine 5'-monophosphate (AMP) induced bronchoconstriction in asthmatic airways

scientific article published on June 1992

Replacing animal experiments: choices, chances and challenges

scientific article published on 01 September 2007

Report of an international workshop on risk and safety of asthma therapy

scientific article published on February 1994

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0.

scientific article published on 14 July 2020

Research into lung disease: a call for urgent action

scientific article published on 01 October 2007

Respiratory symptoms in children at schools near a foundry

scientific article

Respiratory symptoms in older people and use of domestic gas appliances

scientific article (publication date: December 1999)

Rethinking the pathogenesis of asthma

scientific article published on September 2009

Reversibility of the allergen-provoked late asthmatic response by an inhaled beta 2-adrenoceptor agonist

scientific article published on 01 March 1994

Revision of the ARRIVE guidelines: rationale and scope

scientific article published in June 2018

Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjects

scientific article published on 31 January 2002

Rhinovirus infection up-regulates eotaxin and eotaxin-2 expression in bronchial epithelial cells

scientific article

Rhinovirus is not detectable in peripheral lung tissue after asthma death

scientific article published on June 2003

Rhinovirus-16 induced release of IP-10 and IL-8 is augmented by Th2 cytokines in a pediatric bronchial epithelial cell model

scientific article

Rhinovirus-induced alterations on peripheral blood mononuclear cell phenotype and costimulatory molecule expression in normal and atopic asthmatic subjects.

scientific article published in April 2002

Rhinoviruses in the pathogenesis of asthma: the bronchial epithelium as a major disease target

scientific article published in September 2006

Risk factors and characteristics associated with severe and difficult to treat asthma phenotype: an analysis of the ENFUMOSA group of patients based on the ECRHS questionnaire

scientific article published on July 2005

Risk of first-generation H(1)-antihistamines: a GA(2)LEN position paper

scientific article published on 08 February 2010

Road ahead to respiratory health: experts chart future research directions.

scientific article published on 11 March 2009

Role of B7-CD28/CTLA-4 costimulation and NF-kappa B in allergen-induced T cell chemotaxis by IL-16 and RANTES

scholarly article by R Hidi et al published 1 January 2000 in Journal of Immunology

Role of adenylate cyclase in immunologic release of mediators from rat mast cells: agonist and antagonist effects of purine- and ribose-modified adenosine analogs

scientific article

Role of carbohydrates in repair of human respiratory epithelium using an in vitro model

scientific article published in October 2003

Role of cysteinyl leukotrienes in adenosine 5'-monophosphate induced bronchoconstriction in asthma

scientific article published on April 2002

Role of deficient type III interferon-λ production in asthma exacerbations

article

Role of leukotrienes in exercise-induced asthma. Inhibitory effect of ICI 204219, a potent leukotriene D4 receptor antagonist

scientific article (publication date: April 1992)

Role of mast cells and basophils in asthma.

scientific article published on January 1995

Role of nasal interleukin-8 in neutrophil recruitment and activation in children with virus-induced asthma

scientific article published in April 1997

Role of tumor necrosis factor alpha in asthma

scientific article published in November 2004

Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling

scientific article

SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS

scientific article published in The Lancet

Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial

scientific article published on 12 November 2020

Safety and tolerability of omalizumab

scientific article

Science, medicine, and the future. Allergic disorders

scientific article

Seasonal allergic conjunctivitis is accompanied by increased mast cell numbers in the absence of leucocyte infiltration

scientific article published on 01 September 1997

Sensitivity to Parietaria pollen in the Southampton area as determined by skin-prick and RAST tests.

scientific article published in November 1988

Severe asthma in adults: what are the important questions?

scientific article

Severe eosinophilic asthma: a roadmap to consensus

scientific article published in May 2017

Short-term ozone exposure upregulates P-selectin in normal human airways

scientific article

Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium

scientific article published on 01 November 2001

Skin responses to bradykinin, kallidin, and [desArg9]-bradykinin in nonatopic and atopic volunteers

scientific article published on 01 November 1993

Smoking habits in a cohort of U.K. adolescents

scientific article published on 01 April 2000

Sodium cromoglycate in childhood asthma

scientific article

Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life

scientific article

Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline

scientific article

Spectrum of activity of soluble intercellular adhesion molecule-1 against rhinovirus reference strains and field isolates

scientific article published on June 1994

Sputum IL-6 concentrations in severe asthma and its relationship with FEV1

scientific article published on 29 September 2010

Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma

scientific article

Staphylococcus aureus and its IgE-inducing enterotoxins in asthma: current knowledge

scientific article published on 03 April 2020

Starch peritonitis: an immunological study

scientific article published on March 1973

Stimulation of human airway epithelial cells by platelet activating factor (PAF) and arachidonic acid produces 15-hydroxyeicosatetraenoic acid (15-HETE) capable of contracting bronchial smooth muscle

scientific article published in January 1992

Stratified approaches to the treatment of asthma

scientific article published on August 2013

Structural and secretory characteristics of bovine lung and skin mast cells: evidence for the existence of heterogeneity ⬇️

scientific article published on March 1, 1991

Studies of cellular mechanisms for the generation of superoxide by guinea-pig eosinophils and its dissociation from granule peroxidase release

scientific article published in November 1990

Suggestive evidence for genetic linkage between IgE phenotypes and chromosome 14q markers.

scientific article published in June 1999

Summary of recommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma

scientific article published on June 2004

Susceptibility genes in severe asthma

scientific article published on July 2006

Symptoms, atopy, and bronchial response to methacholine in parents with asthma and their children

scientific article

T cell receptor (TCR) Vbeta gene usage in bronchoalveolar lavage and peripheral blood T cells from asthmatic and normal subjects

scientific article published in June 1998

TGF-beta isoform release and activation during in vitro bronchial epithelial wound repair

scientific article published on 01 January 2002

TNF alpha is localized to nasal mucosal mast cells and is released in acute allergic rhinitis

article

TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation

scientific article published on 28 April 2013

Tachyphylaxis to inhaled histamine in asthma: its significance and relationship to basal airway responsiveness.

scientific article published in August 1990

Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease

scientific article published on January 2002

Temporal association between pulmonary inflammation and antioxidant induction following hyperoxic exposure of the preterm guinea pig.

scientific article

Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways

scientific article published in January 1987

Terfenadine, a potent histamine H1-receptor antagonist in the treatment of grass pollen sensitive asthma

scientific article

The 1992 Cournand Lecture. Asthma: past, present and future

scientific article published on November 1993

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

scientific article published on 14 July 2020

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

scientific article published on 15 July 2020

The ARRIVE guidelines 2.0: updated guidelines for reporting animal research

scientific article published on 14 July 2020

The ARRIVE guidelines 2.0: updated guidelines for reporting animal research

scientific article published on 20 July 2020

The BREATHE study: Breathing REtraining for Asthma--Trial of Home Exercises. a protocol summary of a randomised controlled trial.

scientific article published in June 2013

The Brussels Declaration: the need for change in asthma management ⬇️

scientific article

The European Respiratory Society evaluates its 2013-2018 strategic plan implementation

scientific article published in March 2016

The European Respiratory Society fellowship programme: supporting young careers and building networks

scientific article published in September 2013

The European Respiratory Society plans its future: the 2013-2018 strategic plan

scientific article published in April 2014

The Future of Asthma Care: Personalized Asthma Treatment

scientific article

The Genetics of Allergic Disease and Asthma

The Link Between Asthma and COPD. Foreword, summary and conclusions

scientific article

The Quintiles Prize Lecture 2004. The identification of the adenosine A2B receptor as a novel therapeutic target in asthma

scientific article published in August 2005

The Role of Histamine in Allergen and Adenosine-Induced Bronchoconstriction

scientific article published on 01 January 1987

The T cell and the airway's fibrotic response in asthma

scientific article

The acetaminophen enigma in asthma

scientific article published on 01 January 2011

The action of purines on human airways

scientific article

The airway epithelium is central to the pathogenesis of asthma

scientific article published on March 2008

The airway epithelium: structural and functional properties in health and disease

scientific article published on December 2003

The anaphylaxis hypothesis of sudden infant death syndrome (SIDS): mast cell degranulation in cot death revealed by elevated concentrations of tryptase in serum

scientific article published on 01 December 1994

The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma

scientific article

The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation

scientific article

The association of the cytoplasmic domains of interleukin 4 receptor alpha and interleukin 13 receptor alpha 2 regulates interleukin 4 signaling

scientific article published on 20 September 2013

The biodiversity hypothesis and allergic disease: world allergy organization position statement

scientific article

The bronchial epithelial origins of asthma

scientific article

The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma

scientific article

The bronchial epithelium as a target for inflammatory attack in asthma

scientific article

The bronchial epithelium in asthma--much more than a passive barrier.

scientific article published in February 2001

The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men.

scientific article

The cellular and mediator basis of asthma in relation to natural history.

scientific article

The combined effects of two pairs of mediators, adenosine with methacholine and prostaglandin D2 with histamine, on airway calibre in asthma

The contribution of histamine release and vagal reflexes, alone and in combination, to exercise-induced asthma ⬇️

scientific article published on 01 September 1993

The contribution of histamine release to bronchoconstriction provoked by inhaled benzalkonium chloride in asthma

scientific article

The contribution of mast cell mediators to acute allergic reactions in human skin and airways

scientific article published on January 1988

The contribution of neurogenic reflexes to hypertonic saline-induced bronchoconstriction in asthma.

scientific article published in July 1993

The contribution of transforming growth factor-beta and epidermal growth factor signalling to airway remodelling in chronic asthma

scientific article

The current state of respiratory research in the UK.

scientific article published on 20 July 2015

The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma.

scientific article published in June 2006

The discovery and role of ADAM33, a new candidate gene for asthma

scientific article published on 3 August 2004

The distribution of adhesive mechanisms in the normal bronchial epithelium.

scientific article

The effect of 2 weeks treatment with cetirizine on bronchial reactivity to methacholine in asthma

scientific article

The effect of H1-receptor blockade on the development of early- and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma

scientific article published on 01 June 1993

The effect of a novel orally active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic subjects

scientific article published on May 1997

The effect of an increase in inhaled allergen dose after rimiterol hydrobromide on the occurrence and magnitude of the late asthmatic response and the associated change in nonspecific bronchial responsiveness

scientific article

The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response

scientific article published on 01 March 1989

The effect of cromolyn sodium and albuterol on early and late phase bronchoconstriction and airway leukocyte infiltration after allergen challenge of nonanesthetized guinea pigs

scientific article

The effect of dipyridamole on histamine- and adenosine-induced bronchoconstriction in normal and asthmatic subjects.

scientific article published in September 1985

The effect of histamine-H1 receptor antagonism with terfenadine on concentration-related AMP-induced bronchoconstriction in asthma

scientific article published on 01 July 1989

The effect of inhaled 15-(s)-hydroxyeicosatetraenoic acid (15-HETE) on airway calibre and non-specific responsiveness in normal and asthmatic human subjects.

scientific article published in January 1990

The effect of inhaled 5-hydroxytryptamine (5-HT, serotonin) on airway calibre in man.

scientific article

The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial

scientific article

The effect of inhaled allergen on circulating basophils in atopic asthma

scientific article published on 01 August 1992

The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5'-monophosphate and histamine in asthma

scientific article published on 01 May 1991

The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics

scientific article

The effect of local hyperthermia on allergen-induced nasal congestion and mediator release

scientific article published on 01 December 1993

The effect of methyltransferase inhibitors on histamine release from human dispersed lung mast cells activated with anti-human IgE and calcium ionophore A23187

scientific article published on 01 September 1984

The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma

scientific article published in February 1989

The effect of respiratory manoeuvres and pharmacological agents on the pharmacokinetics of nedocromil sodium after inhalation ⬇️

scientific article published on April 1, 1992

The effect of treatment with omalizumab, an anti-IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma

scientific article

The effects of Mycobacterium vaccae on allergen-induced airway responses in atopic asthma.

scientific article published in February 2003

The effects of Th2 cytokines on the expression of ADAM33 in allergen-induced chronic airway inflammation

scientific article published on 25 July 2009

The effects of an oral thromboxane TP receptor antagonist BAY u 3405, on prostaglandin D2- and histamine-induced bronchoconstriction in asthma, and relationship to plasma drug concentrations ⬇️

scientific article published on November 1, 1992

The effects of regular inhaled formoterol and budesonide on preformed Th-2 cytokines in mild asthmatics

scientific article published in December 2002

The effects of regular inhaled formoterol, budesonide, and placebo on mucosal inflammation and clinical indices in mild asthma

scientific article published on 01 January 1999

The effects of theophylline on mucosal inflammation in asthmatic airways: biopsy results

scientific article published on 01 May 1995

The efficacy and therapeutic position of nedocromil sodium

scientific article published on August 1996

The epidemic of allergy and asthma

scientific article published in November 1999

The epidemic of asthma and allergy

scientific article published in March 2004

The epidermal growth factor receptor and its ligand family: their potential role in repair and remodelling in asthma.

scientific article

The epithelium takes centre stage in asthma and atopic dermatitis

scientific article published on 27 April 2007

The era of research collaborations: new models for working together

scientific article published on 3 January 2017

The ever-expanding ERS fellowship programmes: achievements over the past 3 years

scientific article published in September 2016

The expanding role of immunopharmacology: IUPHAR Review 16

scientific article (publication date: September 2015)

The expression of leukocyte-endothelial adhesion molecules is increased in perennial allergic rhinitis

scientific article published on October 1, 1992

The free radical basis of air pollution: focus on ozone

scientific article published on November 1995

The future of asthma research and development: a roadmap from the European Asthma Research and Innovation Partnership (EARIP).

scientific article published in May 2017

The future of lung research in the UK.

scientific article published on December 2007

The future of technologies for personalised medicine

scientific article published on September 2012

The generation of prostaglandins by human lung and their effects on airway function in man.

scientific article published on January 1986

The genetic basis of atopic asthma

scientific article

The genetics of asthma: ADAM33 as an example of a susceptibility gene

scientific article

The glutamine 27 β-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families ⬇️

scientific article published on August 1, 1997

The health effects of fine particulate air pollution

scientific article published on 27 November 2019

The immunoglobulin E- and calcium-dependent release of histamine and eicosanoids from human dispersed mastocytosis spleen cells

scientific article published on 01 March 1988

The immunopharmacology of mild asthma

scientific article published on November 1996

The importance of primary care research in the management of respiratory disease

scientific article published on 01 March 2012

The in vivo potency and selectivity of azelastine as an H1 histamine-receptor antagonist in human airways and skin

scientific article published on 01 December 1988

The inflammatory basis of asthma and its implications for drug treatment

scientific article published on June 1996

The inflammatory marker serum eosinophil cationic protein (ECP) compared with PEF as a tool to decide inhaled corticosteroid dose in asthmatic patients.

scientific article published in February 2002

The influence of cyclooxygenase inhibition on the loss of bronchoconstrictor response to repeated bradykinin challenge in asthma

scientific article published on 01 September 1990

The influence of increased bronchial responsiveness, atopy, and serum IgE on decline in FEV1. A longitudinal study in the elderly

scientific article published in March 1995

The influence of ipratropium bromide and sodium cromoglycate on benzalkonium chloride-induced bronchoconstriction in asthma

scientific article

The influence of terfenadine and ipratropium bromide alone and in combination on bradykinin-induced nasal symptoms and plasma protein leakage

scientific article published on July 1, 1992

The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma

scientific article published on 01 November 1989

The inhibitory effect of azelastine hydrochloride on histamine- and allergen-induced bronchoconstriction in atopic asthma

scientific article published on 01 May 1989

The innate antiviral response upregulates IL-13 receptor α2 in bronchial fibroblasts

scientific article published on 12 October 2012

The long‐acting β2‐agonist salmeterol xinafoate: effects on airway inflammation in asthma

scientific article published on 01 August 1999

The mast cell and its function in allergic disease

scientific article published on May 1991

The mast cell as a primary effector cell in the pathogenesis of asthma

scientific article published on February 1986

The mast cell as a source of cytokines in asthma

scientific article published on October 1996

The mechanisms, diagnosis, and management of severe asthma in adults

scientific article published on August 2006

The mediator and cellular basis of the allergic response

scientific article published on 01 January 1988

The metabolism of prostaglandin D2 after inhalation or intravenous infusion in normal men

scientific article published on 01 November 1988

The metabolism of prostaglandin D2. Evidence for the sequential conversion by NADPH and NAD+ dependent pathways

scientific article published on 01 October 1989

The modulator effect of bradykinin with respect to tracheobronchial clearance in healthy subjects

scientific article published on October 1, 1992

The molecular and cell biology of allergy.

scientific article

The mouse trap: It still yields few answers in asthma

scientific article published on 01 December 2006

The natural history of bronchial hyperresponsiveness.

scientific article

The natural history of respiratory symptoms in a cohort of adolescents

scientific article published in August 1998

The pathogenesis and significance of bronchial hyper-responsiveness in airways disease

scientific article published on December 1987

The pathogenesis of severe asthma: A consensus report from the workshop on pathogenesis

scientific article published in September 1987

The pre-term guinea-pig: a model for the study of neonatal lung disease

scientific article published on 1 September 1991

The protective effect of inhaled leukotriene D4 receptor antagonist ICI 204,219 against exercise-induced asthma

scientific article published on June 1993

The pulmonary deposition of two aerosol preparations of nedocromil sodium delivered by MDI assessed by single photon emission computed tomography

scientific article published on 01 March 1996

The relationship between anthropometric measurements at birth: asthma and atopy in childhood

scientific article published on 01 March 1999

The relationship between cyclic amp changes and histamine release from basophil-rich human leucocytes ⬇️

scientific article published on 01 September 1983

The relationship between mast cell-mediator release and bronchial reactivity in allergic asthma

scientific article

The relationship between pneumonia in early childhood and impaired lung function in late adult life

scientific article

The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis

scientific article published on 01 September 1996

The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma ⬇️

scientific article published on March 1, 1992

The release and role of inflammatory mediators in asthma

scientific article published on January 1985

The reproducibility and effect on non-specific airway responsiveness of inhaled prostaglandin D2 and leukotriene D4 in asthmatic subjects

scientific article

The role of ADAM33 in the pathogenesis of asthma

scientific article published on 15 November 2003

The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthma

scientific article published on 01 December 2001

The role of IgE in allergen-induced inflammation and the potential for intervention with a humanized monoclonal anti-IgE antibody

scientific article

The role of LTA4H and ALOX5AP polymorphism in asthma and allergy susceptibility.

scientific article published on 10 June 2008

The role of Toll-like receptors and related receptors of the innate immune system in asthma

scientific article published in February 2006

The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial.

scientific article published in February 2008

The role of anti-IgE therapies in the treatment of asthma.

scientific article

The role of histamine in asthma

scientific article published on January 2010

The role of leukotrienes and prostaglandins in asthma: evidence from clinical investigations

scientific article published on January 1990

The role of mast cells and basophils in inflammation

scientific article

The role of mast cells in the pathogenesis of asthma

scientific article published on September 1985

The role of the airway epithelium and its interaction with environmental factors in asthma pathogenesis

scientific article published on December 2009

The role of the eosinophil in asthma

scientific article published on March 1991

The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma

scientific article published on 01 February 2003

The role of the mast cell in the pathophysiology of asthma

scientific article

The role of theophylline in the management of chronic asthma in adults

scientific article published on March 1996

The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma.

scientific article published in April 1991

The sentinel role of the airway epithelium in asthma pathogenesis

scientific article published on July 2011

The significance of antinuclear and DNA antibodies in cryptogenic fibrosing alveolitis

scientific article

The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects

scientific article published on July 1992

The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma.

scientific article published on 14 April 2008

The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts

scientific article (publication date: July 2004)

The temporal relationship between the neural and vascular actions of kallidin within the nose

scientific article published on January 1993

The trials and tribulations of anti-IL-5 em leader

scientific article published on 01 March 2002

The use of omalizumab in the treatment of severe allergic asthma: A clinical experience update

scientific article published on 10 April 2009

The use of pharmacogenetics in the treatment of asthma

scientific article published on 01 August 2005

The validation of a fluoroimmunoassay for the determination of theophylline concentration in dried blood spots suitable for domiciliary therapeutic drug monitoring ⬇️

scientific article published on January 31, 1984

Theophylline inhibits the release of eosinophil survival cytokines--is Raf-1 the protein kinase A target?

scientific article published on 01 August 1998

Three-dimensional description of pulmonary deposition of inhaled aerosol using data from multimodality imaging

scientific article published on May 1996

Toll-like receptor 4 polymorphism and severity of atopy in asthmatics

scientific article

Toll-like receptor polymorphisms and allergic disease: interpreting the evidence from genetic studies

scientific article published in February 2004

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response

scientific article

Treatable traits: toward precision medicine of chronic airway diseases

scientific article published on February 2016

Treating hay fever

scientific article published on July 1985

Treatment of allergic airways disease with anti-IgE

scientific article published on 01 January 1998

Treatment strategies for allergy and asthma

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Trends in asthma mortality. Data on seasonality of deaths due to asthma were omitted from paper but editorial's author did not know

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