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List of works by Dieter Hoelzer

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Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)

scientific article (publication date: 10 December 2002)
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

scientific article
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL

scientific article (publication date: 15 June 2006)
Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicentre, randomised, phase 3 non-inferiority trial

scientific article published on February 20, 2013
Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival

scientific article published on 16 May 2011
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

scientific article
Phase II Trial of the Anti-CD19 Bispecific T Cell–Engager Blinatumomab Shows Hematologic and Molecular Remissions in Patients With Relapsed or Refractory B-Precursor Acute Lymphoblastic Leukemia

scientific article published on November 10, 2014
A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias

scientific article
Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin's lymphoma

scientific article
Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia

scientific article
Incidence and Prognostic Influence of DNMT3A Mutations in Acute Myeloid Leukemia

scientific article published on June 13, 2011
Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell–engaging CD19/CD3-bispecific BiTE antibody blinatumomab

scientific article published on May 16, 2012
Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation.

scientific article
Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis

scientific article published in March 2002
Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL)

scientific article published on 25 April 2006
Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies

scientific article published on 22 March 2012
Molecular relapse in adult standard-risk ALL patients detected by prospective MRD monitoring during and after maintenance treatment: data from the GMALL 06/99 and 07/03 trials

scientific article
Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia

scientific article
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

scientific article published on 19 April 2013
Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia

scientific article
Outcome of adult patients with T-lymphoblastic lymphoma treated according to protocols for acute lymphoblastic leukemia

scientific article published in June 2002
Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial

scientific article
High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults

scientific article published on 5 September 2006
Mutational spectrum of adult T-ALL

scientific article published on February 20, 2015
Dasatinib and low-intensity chemotherapy in elderly patients with Philadelphia chromosome-positive ALL

scientific article published on 27 April 2016
The role of microRNA-196a and microRNA-196b as ERG regulators in acute myeloid leukemia and acute T-lymphoblastic leukemia

scientific article published on 8 June 2010
Treatment of adult acute lymphoblastic leukemia

scientific article published on January 2006
The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group

scientific article published on 14 January 2009
International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia

scientific article
Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia

scientific article published on October 2009
Chemoimmunotherapy in acute lymphoblastic leukemia

scientific article published on 29 September 2011
Low ERG and BAALC expression identifies a new subgroup of adult acute T-lymphoblastic leukemia with a highly favorable outcome

scientific article
Histone deacetylase 3, a class I histone deacetylase, suppresses MAPK11-mediated activating transcription factor-2 activation and represses TNF gene expression

scientific article
FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors

scientific article
Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis

scientific article published on 25 August 2016
Treatment with monoclonal antibodies in acute lymphoblastic leukemia: current knowledge and future prospects

scientific article published on 26 November 2003
T-cell lymphoblastic lymphoma and T-cell acute lymphoblastic leukemia: a separate entity?

scientific article published on January 2009
Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy

scientific article published on 23 August 2011
Early prediction of response in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) treated with imatinib

scientific article published on 23 October 2003
Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia

scientific article published on 18 October 2011
Mechanisms of resistance to STI571 (Imatinib) in Philadelphia-chromosome positive acute lymphoblastic leukemia

scientific article published on April 2004
NUP214-ABL1 in adult T-ALL: the GMALL study group experience.

scientific article published on 27 July 2006
Liposomal cytarabine is effective and tolerable in the treatment of central nervous system relapse of acute lymphoblastic leukemia and very aggressive lymphoma

scientific article
Outcomes of patients with Burkitt lymphoma older than age 40 treated with intensive chemotherapeutic regimens

scientific article
High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia

scientific article published on 11 January 2010
Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization

scientific article published on 15 February 2013
Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

scientific article
AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor

scientific article (publication date: December 2002)
Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia

scientific article
Targeted therapies in the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia

scientific article

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