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List of works by Victor J. Hruby

Antinociceptive and nociceptive actions of opioids

scientific article published in October 2004

Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillamines

scientific article

Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives

scientific article

Development of Potent μ and δ Opioid Agonists with High Lipophilicity ⬇️

scientific article published on December 3, 2010

Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands

scientific article

Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies

scientific article

Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord

scientific article

Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities

scientific article

Improving metabolic stability by glycosylation: bifunctional peptide derivatives that are opioid receptor agonists and neurokinin 1 receptor antagonists

scientific article

Melanocortin receptors, melanotropic peptides and penile erection

scientific article

Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors

scientific article

New paradigms and tools in drug design for pain and addiction

scientific article published on 14 July 2006

Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain

scientific article published on 20 April 2011

Role of NK-1 neurotransmission in opioid-induced hyperalgesia

scientific article

Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands ⬇️

scientific article published on August 24, 2011

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