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List of works by Linda Birnbaum

15 Years Out: Reinventing ICCVAM

scientific article published on February 1, 2013

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) distribution and cytochrome P4501A induction in young adult and senescent male mice

scientific article published in March 1995

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters embryonic palatal medial epithelial cell differentiation in vitro

scientific article

2,3,7,8-Tetrachlorodibenzo-p-dioxin in Pregnant Long Evans Rats: Disposition to Maternal and Embryo/Fetal Tissues,

scientific article published on 01 October 1998

2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated oxidative stress in CYP1A2 knockout (CYP1A2-/-) mice

scientific article published on 01 October 1999

2,3,7,8-Tetrachlorodibenzofuran tissue distribution and excretion in guinea pig.

scientific article published in February 1981

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disrupts early morphogenetic events that form the lower reproductive tract in female rat fetuses.

scientific article published in January 2002

2,4,6-Tribromophenol Disposition and Kinetics in Rodents: Effects of Dose, Route, Sex, and Species

scientific article published on 01 May 2019

2,4,6-Tribromophenol Exposure Decreases P-glycoprotein Transport at the Blood-Brain Barrier

scientific article published on 31 July 2019

2,4,6-Tribromophenol disposition and kinetics in pregnant and nursing Sprague Dawley rats

scientific article published on 11 August 2020

5th International PCB Workshop--summary and implications

scientific article

A Multicompartment Geometric Model of the Liver in Relation to Regional Induction of Cytochrome P450s

article

A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism.

scientific article published on December 1990

A mixture of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and non-ortho polychlorinated biphenyls (PCBs) changed the lipid content of pregnant Long Evans rats

scientific article

A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicals

scientific article

A pharmacodynamic analysis of TCDD-induced cytochrome P450 gene expression in multiple tissues: dose- and time-dependent effects

scientific article published on August 1998

A physiological model for simulation of benzene metabolism by rats and mice

scientific article

A physiologically based pharmacokinetic model for 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in the rat: tissue distribution and CYP1A induction

scientific article published in July 1993

A physiologically based pharmacokinetic model for developmental exposure to BDE-47 in rats.

scientific article published on 31 October 2009

A repeat call for the banning of asbestos

scientific article

A research strategy to discover the environmental causes of autism and neurodevelopmental disabilities

scientific article

A single gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts the adult uterine response to estradiol in mice

scientific article published on 19 September 2013

A toxikinetic model for simulation of benzene metabolism

scientific article published on 01 January 1989

Absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) after low dose dermal exposure.

scientific article

Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons

scientific article published on 15 May 2008

Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: association of measured tissue concentrations with developmental effects

scientific article

Acute inhalation exposure of azodicarbonamide in the guinea pig.

scientific article published in February 1987

Acute toxicity of perfluorodecanoic acid in C57BL/6 mice differs from 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article published on 01 November 1989

Advances in Environmental Health and Disaster Research 15 Years After Hurricane Katrina

scientific article published on 01 October 2020

Advancing the next generation of health risk assessment

scientific article published on 8 August 2012

Age-independent, gray matter-localized, brain-enhanced oxidative stress in male fischer 344 rats: brain levels of F(2)-isoprostanes and F(4)-neuroprostanes

scientific article

Age-related changes in benzene disposition in male C57BL/6N mice described by a physiologically based pharmacokinetic model

scientific article published on 01 December 1994

Age-related changes in carcinogen metabolism.

scientific article

Age-related changes in dermal absorption of 2,3,7, 8-tetrachlorodibenzo-p-dioxin and 2,3,4,7,8-pentachlorodibenzofuran

scientific article published on 01 July 1990

Age-related changes in disposition and metabolism of benzene in male C57BL/6N mice

scientific article published on 01 November 1991

Age-related changes in glucose metabolizing enzymes in spleen, thymus, and pulmonary lavage cells from F344 rats

scientific article published on 01 August 1984

Age-related changes in glucuronidation and deglucuronidation in liver, small intestine, lung, and kidney of male Fischer rats

scientific article published on 01 January 1985

Age-related changes in the disposition of benzyl acetate. A model compound for glycine conjugation.

scientific article

Age-related changes in the metabolism and excretion of allyl isothiocyanate. A model compound for glutathione conjugation

scientific article published on 01 July 1986

Agent Orange exposure, Vietnam war veterans, and the risk of prostate cancer

scientific article published in July 2009

Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression

scientific article published in May 1994

Altered hepatic drug metabolism in senescent mice

scientific article published on 01 January 1980

Alternatives to PFASs: perspectives on the science

scientific article published on May 2015

An Examination of Child and Adolescent Neurodevelopment Through National Institutes of Health Studies

scientific article published on 22 January 2020

An assessment of dioxin exposure across gestation and lactation using a PBPK model and new data from Seveso

scientific article

An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology

scientific article published on October 2009

Anniston community health survey: Follow-up and dioxin analyses (ACHS-II)--methods.

scientific article

Applying research to public health questions: biologically relevant exposures

scientific article published on April 2010

Applying research to public health questions: timing and the environmentally relevant dose

scientific article published on November 2009

Approaches for assessing risks to sensitive populations: lessons learned from evaluating risks in the pediatric population

scientific article

Arsenic and Environmental Health: State of the Science and Future Research Opportunities

scientific article

Assessment of host resistance to Trichinella spiralis in mice following preinfection exposure to 2,3,7,8-TCDD.

scientific article

Assessment of polybrominated diphenyl ether exposures and health risks associated with consumption of southern Mississippi catfish

scientific article published on 01 September 2008

Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004

scientific article

Basic science: Bedrock of progress

scientific article published on March 2016

Benzene dosimetry in experimental animals: relevance for risk assessment

scientific article

Benzene hemoglobin adducts in mice and rats: characterization of formation and physiological modeling

scientific article published in October 1990

Biomonitoring of Metals, Polybrominated Diphenyl Ethers, Polychlorinated Biphenyls, Persistent Pesticides in Vietnamese Female Electronic Waste Recyclers

scientific article published on 2 November 2017

Bisphenol A (BPA) in U.S. food

scientific article

Bisphenol A, Bisphenol S, and 4-Hydroxyphenyl 4-Isoprooxyphenylsulfone (BPSIP) in Urine and Blood of Cashiers

scientific article

Brominated and chlorinated flame retardants: the San Antonio Statement

scientific article published on December 2010

Brominated flame retardants: cause for concern?

scientific article

CHDS: A national treasure that keeps on giving

scientific article published on 22 February 2020

CYP1A2 is not required for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunosuppression

scientific article published in April 2004

Cancer and developmental exposure to endocrine disruptors

scientific article

Cancer and the environment: Filling knowledge gaps together

scientific article

Catfish consumption as a contributor to elevated PCB levels in a non-Hispanic black subpopulation

scientific article published on 14 April 2008

Cellular alterations and enhanced induction of cleft palate after coadministration of retinoic acid and TCDD

scientific article published on 01 June 1989

Changes in hepatic microsomal membrane fluidity with age

scientific article published on 01 January 1982

Changing the Climate of Respiratory Clinical Practice. Insights from the 2016 Climate and Health Assessment of the U.S. Global Change Research Program

scientific article published on August 2016

Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure

publication published in 2007

Characterization of hemoglobin adduct formation in mice and rats after administration of [14C]butadiene or [14C]isoprene.

scientific article published on August 1989

Characterization of the peak period of sensitivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin

scientific article

Chemical characterization and disposition studies with 1,2,7,8-tetrabromodibenzofuran in the rat

scientific article published on 01 January 1994

Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: critical parameters of the CALUX procedure that impact assay results

scientific article

Childhood obesity and environmental chemicals

scientific article

Commemorating Toxicology at the National Institute of Environmental Health Sciences on the Occasion of Its 50th Anniversary

scientific article

Community corner. Striking the balance in multiple sclerosis

scientific article published on 01 May 2008

Comparative ability of various PCBs, PCDFs, and TCDD to induce cytochrome P450 1A1 and 1A2 activity following 4 weeks of treatment

scientific article published on 01 January 1993

Comparative absorption and bioaccumulation of polybrominated diphenyl ethers following ingestion via dust and oil in male rats.

scientific article

Comparative dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin and three polychlorinated dibenzofurans

scientific article published on 01 January 1989

Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disposition following pulmonary, oral, dermal, and parenteral exposures to rats

scientific article published on 01 May 1996

Comparison of Metal Levels between Postmortem Brain and Ventricular Fluid in Alzheimer's Disease and Nondemented Elderly Controls.

scientific article published on 31 December 2015

Comparison of the use of a physiologically based pharmacokinetic model and a classical pharmacokinetic model for dioxin exposure assessments

scientific article

Comparisons of the effects of TCDD and hydrocortisone on growth factor expression provide insight into their interaction in the embryonic mouse palate

scientific article published on January 1992

Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A

scientific article

Contamination of U.S. butter with polybrominated diphenyl ethers from wrapping paper

scientific article

Cross-sectional Associations between Exposure to Persistent Organic Pollutants and Leukocyte Telomere Length among U.S. Adults in NHANES, 2001-2002

scientific article published on 9 October 2015

Crystallographic analysis and mimicking of estradiol binding: Pedersen et al. Respond

scientific article published on April 2014

Daily cycle of bHLH-PAS proteins, Ah receptor and Arnt, in multiple tissues of female Sprague-Dawley rats

scientific article published on 01 November 1998

Decreased ligand binding to the hepatic glucocorticoid and epidermal growth factor receptors after 2,3,4,7,8-pentachlorodibenzofuran and 1,2,3,4,7,8-hexachlorodibenzofuran treatment of pregnant mice.

scientific article

Dermal disposition of Tetrabromobisphenol A Bis(2,3-dibromopropyl) ether (TBBPA-BDBPE) using rat and human skin

scientific article published on 24 November 2018

Designing safer chemicals

scientific article published on January 2013

Determination of parameters responsible for pharmacokinetic behavior of TCDD in female Sprague-Dawley rats

scientific article published on 01 November 1997

Development of a refined database of mammalian relative potency estimates for dioxin-like compounds.

scientific article

Developmental Origins of Health and Disease: Integrating Environmental Influences.

scientific article

Developmental effects of dioxins and related endocrine disrupting chemicals.

scientific article published on December 1995

Developmental exposure to a commercial PBDE mixture, DE-71: neurobehavioral, hormonal, and reproductive effects

scientific article published on 7 April 2010

Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo.

scientific article published in October 1995

Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors

scientific article published on 18 May 2009

Differences in the metabolism and disposition of inhaled [3H]benzene by F344/N rats and B6C3F1 mice

scientific article published on 01 June 1988

Differences in the pathways for metabolism of benzene in rats and mice simulated by a physiological model

scientific article

Differences in tissue distribution of HBCD alpha and gamma between adult and developing mice

scientific article (publication date: September 2011)

Differential effects of two lots of aroclor 1254 on enzyme induction, thyroid hormones, and oxidative stress.

scientific article

Differential effects of two lots of aroclor 1254: congener-specific analysis and neurochemical end points

scientific article published on November 1, 2001

Differential toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57BL/6J mice congenic at the Ah Locus

scientific article published on 01 July 1990

Dioxin and polychlorinated biphenyl concentrations in mother's serum and the timing of pubertal onset in sons

scientific article

Dioxin and the AH Receptor: Synergy of Discovery

scientific article published on 02 February 2017

Dioxin-like compound exposures and DNA methylation in the Anniston Community Health Survey Phase II

scientific article published on 22 June 2020

Dioxin-like effects observed in male rats following exposure to octachlorodibenzo-p-dioxin (OCDD) during a 13-week study.

scientific article published in March 1988

Dioxins and cardiovascular disease mortality

journal article published in 2008

Dioxins and endometriosis: a plausible hypothesis.

scientific article

Dioxins: an overview

scientific article

Dioxins: model chemicals for assessing receptor-mediated toxicity.

scientific article published on September 1995

Disposition and excretion of 2,3,4,7,8-pentachlorodibenzofuran in the rat

scientific article published on 01 September 1987

Disposition and excretion of 2,3,7,8-tetrachlorodibenzofuran in the rat

scientific article published on 01 September 1980

Disposition and excretion of intravenous 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in rats

scientific article published on May 1991

Disposition and metabolism of 2,3-[14C]dichloropropene in rats after inhalation.

scientific article

Disposition of 1,2,3,7,8-pentachlorodibenzofuran in the rat

scientific article published on 01 September 1988

Disposition of 2,3,7,8-tetrabromodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat: biliary excretion and induction of cytochromes CYP1A1 and CYP1A2.

scientific article published in October 1991

Disposition of 4,4'-thiobis(6-t-butyl-m-cresol) in rats

scientific article published on 01 November 1983

Disposition of BDE 47 in developing mice

scientific article published on 11 January 2006

Disposition of [14C]methyl bromide in Fischer-344 rats after oral or intraperitoneal administration

scientific article published on 01 September 1984

Disposition of [14C]methyl bromide in rats after inhalation

scientific article published in April 1985

Disposition of benzo(f)quinoline in male rats

scientific article published on 01 January 1985

Disposition of citral in male Fischer rats

scientific article published on 01 September 1988

Disposition of inhaled 1-chloro-2-propanol in F344/N rats.

scientific article published on September 1988

Disposition of inhaled isoprene in B6C3F1 mice

scientific article published on 01 March 1991

Disposition of octachlorodibenzo-p-dioxin (OCDD) in male rats

scientific article published on 01 March 1988

Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant long evans rats and the transfer to offspring.

scientific article published in June 2001

Disposition of the Emerging Brominated Flame Retardant, 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate, in Female SD Rats and Male B6C3F1 Mice: Effects of Dose, Route, and Repeated Administration

scientific article published on 9 September 2016

Disposition of the emerging brominated flame retardant, bis(2-ethylhexyl) tetrabromophthalate, in female Sprague Dawley rats: effects of dose, route and repeated administration

scientific article published on 21 April 2016

Disposition of three glycol ethers administered in drinking water to male F344/N rats.

scientific article published in March 1990

Disruption of estrogen homeostasis as a mechanism for uterine toxicity in Wistar Han rats treated with tetrabromobisphenol A.

scientific article published on 14 March 2016

Distribution and excretion of 2,3,6,2',3',6'- and 2,4,5,2',4',5'-hexachlorobiphenyl in senescent rats

scientific article published on 01 September 1983

Distribution and excretion of 2,3,7,8-tetrachlorodibenzofuran in C57BL/6J and DBA/2J mice

scientific article published on 01 July 1981

Dose-dependent localization of TCDD in isolated centrilobular and periportal hepatocytes

scientific article

Dose-response relationships for disposition and hepatic sequestration of polyhalogenated dibenzo-p-dioxins, dibenzofurans, and biphenyls following subchronic treatment in mice

scientific article published on 01 December 1998

Dose-response relationships for induction of CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin in female mice following subchronic exposure to polychlorinated biphenyls.

scientific article

Dose-response relationships for polyhalogenated dioxins and dibenzofurans following subchronic treatment in mice. I. CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin

scientific article published on 01 December 1997

Dose-response relationships in mice following subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: CYP1A1, CYP1A2, estrogen receptor, and protein tyrosine phosphorylation

scientific article published on 01 January 1994

Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice

scientific article published on 01 February 1995

E-Waste and Harm to Vulnerable Populations: A Growing Global Problem

scientific article (publication date: May 2016)

Early-life prevention of non-communicable diseases

scientific article

Editorial Independence for EHP.

scientific article published in July 2009

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on influenza virus host resistance in mice.

scientific article published in January 1996

Effect of GenX on P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 at the Blood-Brain Barrier

scientific article published on 26 March 2020

Effect of age on the in vitro percutaneous absorption of phenols in mice

scientific article published on 01 April 1994

Effect of dose on the absorption and excretion of [14C]benzene administered orally or by inhalation in rats and mice

scientific article published on 01 February 1987

Effect of dose on the disposition of methoxyethanol, ethoxyethanol, and butoxyethanol administered dermally to male F344/N rats

scientific article published on 01 July 1992

Effect of dose, time, and pretreatment on the biliary excretion and tissue distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.

scientific article published in November 1993

Effect of exposure concentration on the disposition of inhaled butoxyethanol by F344 rats

scientific article published on 01 June 1992

Effect of exposure concentration, exposure rate, and route of administration on metabolism of benzene by F344 rats and B6C3F1 mice

scientific article published on 01 July 1989

Effect of exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) on mitochondrial DNA (mtDNA) copy number in rats

scientific article published on 04 March 2021

Effect of four-week repeated inhalation exposure to unconjugated azodicarbonamide on specific and non-specific airway sensitivity of the guinea pig

scientific article published on 01 June 1989

Effect of inhaled azodicarbonamide on F344/N rats and B6C3F1 mice with 2-week and 13-week inhalation exposures.

scientific article published in August 1990

Effect of prenatal exposure to TCDD on the promotion of endometriotic lesion growth by TCDD in adult female rats and mice

scientific article

Effect of repeated benzene inhalation exposures on benzene metabolism, binding to hemoglobin, and induction of micronuclei

scientific article (publication date: May 1990)

Effect of repeated benzene inhalation exposures on subsequent metabolism of benzene

scientific article published on 01 January 1989

Effect of vapor concentration on the disposition of inhaled 2,3-dichloropropene in Fischer-344 rats.

scientific article

Effects of CYP1A2 on disposition of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-pentachlorodibenzofuran, and 2,2',4,4',5,5'-hexachlorobiphenyl in CYP1A2 knockout and parental (C57BL/6N and 129/Sv) strains of mice

scientific article

Effects of TCDD on embryonic ureteric epithelial EGF receptor expression and cell proliferation

scientific article

Effects of age and dose on disposition and metabolism of salicylic acid in male Fischer 344 rats

scientific article published on 01 July 1990

Effects of age, sex, and pharmacologic agents on the biliary elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in F344 rats

scientific article published on July 1, 1998

Effects of dose and routes of exposure on the disposition of 2,3,7,8-[3H]tetrabromodibenzo-p-dioxin (TBDD) in the rat

scientific article published on 01 June 1993

Effects of perinatal PBDE exposure on hepatic phase I, phase II, phase III, and deiodinase 1 gene expression involved in thyroid hormone metabolism in male rat pups

scientific article

Effects of thyroid hormones on the induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57BL/6N mice

scientific article published on 01 June 1986

Elevated PBDE levels in pet cats: sentinels for humans?

scientific article

Enhanced potential for oxidative stress in livers of senescent rats by the peroxisome proliferator-activated receptor alpha agonist perfluorooctanoic acid

scientific article published on January 2004

Environmental Chemicals: Evaluating Low-Dose Effects

scientific article published on April 1, 2012

Environmental exposures, breast development and cancer risk: Through the looking glass of breast cancer prevention

scientific article

Environmental justice: a continuing commitment to an evolving concept

scientific article

Erratum: "Marking a New Understanding of Climate and Health".

scientific article published on June 2016

Estimation of human percutaneous bioavailability for two novel brominated flame retardants, 2-ethylhexyl 2,3,4,5-tetrabromobenzoate (EH-TBB) and bis(2-ethylhexyl) tetrabromophthalate (BEH-TEBP)

scientific article

Estimation of octanol-water partition coefficients and correlation with dermal absorption for several polyhalogenated aromatic hydrocarbons

scientific article published on 01 October 1993

Estimation of tetrabromobisphenol A (TBBPA) percutaneous uptake in humans using the parallelogram method

scientific article

Etiology of retinoic acid-induced cleft palate varies with the embryonic stage.

scientific article

Evaluation of the association between persistent organic pollutants (POPs) and diabetes in epidemiological studies: a national toxicology program workshop review

scientific article

Evaluation of the persistence of hydronephrosis induced in mice following in utero and/or lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article published in March 1991

Evidence for the role of the Ah receptor in response to dioxin

scientific article published on 01 January 1994

Evolution in environmental health: incorporating the infectious disease paradigm

scientific article

Exposure assessment for endocrine disruptors: some considerations in the design of studies.

scientific article

Exposure assessment of adult intake of bisphenol A (BPA) with emphasis on canned food dietary exposures

scientific article published on 30 January 2015

Exposure of dioxin-like chemicals in participants of the Anniston community health survey follow-up

Exposure to TCDD during development permanently alters reproductive function in male Long Evans rats and hamsters: reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring with normal androgenic status.

scientific article published in March 1995

Exposure to asbestos-containing vermiculite ore and respiratory symptoms among individuals who were children while the mine was active in Libby, Montana

scientific article

Exposure, effects, and public health challenges: An interview with Linda Birnbaum, Director of the US National Institute of Environmental Health Services

scientific article published on 12 March 2014

Extrapolation of a PBPK model for dioxins across dosage regimen, gender, strain, and species

scientific article

Fate of 2,3,7,8-tetrachlorodibenzofuran in the monkey

scientific article published on 01 February 1981

Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung

scientific article published on April 1998

Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes.

scientific article

From endocrine disruptors to nanomaterials: advancing our understanding of environmental health to protect public health.

scientific article

Gene expression changes in immune response pathways following oral administration of tetrabromobisphenol A (TBBPA) in female Wistar Han rats.

scientific article published on 11 March 2017

Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop

scientific article

Genetic modification of the association between peripubertal dioxin exposure and pubertal onset in a cohort of Russian boys

scientific article

Halogenated flame retardants: do the fire safety benefits justify the risks?

scientific article

Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs).

scientific article

Hexabromocyclododecane (HBCD) stereoisomers in U.S. food from Dallas, Texas

scientific article

Hexabromonaphthalene contaminants of polybrominated biphenyls: chemical composition and disposition in the rat.

scientific article published on October 1983

How Did I Ever Get Here? The 2018 Mildred S. Christian Award Winner

scientific article published on 01 July 2018

How Many Urine Samples Are Needed to Accurately Assess Exposure to Non-Persistent Chemicals? The Biomarker Reliability Assessment Tool (BRAT) for Scientists, Research Sponsors, and Risk Managers

scientific article published on 06 December 2020

Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery

scientific article (publication date: March 1991)

Hypertension in Relation to Dioxins and Polychlorinated Biphenyls from the Anniston Community Health Survey Follow-Up

scientific article published on 20 December 2019

IARC monographs: 40 years of evaluating carcinogenic hazards to humans

journal article published in 2015

ICCVAM: Birnbaum and Stokes Respond.

scientific article published in May 2010

Identifying Cost Savings Associated with NIEHS-Funded Research.

scientific article published on 20 June 2018

Impact of repeated exposure on the toxicokinetics of BDE 47 in mice.

scientific article published on 9 November 2005

Implementing systematic review at the National Toxicology Program: status and next steps

scientific article published in April 2013

Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors

scientific article published on 18 October 2019

In Memoriam: Herbert L. Needleman

scientific article published on 19 September 2017

In vitro synthesis of Escherichia coli ribosomal RNA

scientific article published on 01 March 1973

In vivo effects of bisphenol A in laboratory rodent studies

scientific article

Increased production of mutagenic metabolites of carcinogens by tissues from senescent rodents

scientific article published on November 1, 1979

Induction of cytochrome P450 isoenzymes after toxicokinetic interactions between 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,2',4,4',5,5'-hexachlorobiphenyl in the liver of the mouse

scientific article published on 01 May 1995

Induction of ethoxyresorufin-O-deethylase and inhibition of glucocorticoid receptor binding in skin and liver of haired and hairless HRS/J mice by topically applied 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article published on December 1990

Induction of hepatic mixed function oxidases in senescent rodents

scientific article published on January 1978

Induction of hepatic mixed function oxidases in senescent rodents--II. Effect of polychlorinated biphenyls

scientific article published on January 1978

Induction of oxidative stress in brain tissues of mice after subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

scientific article published in March 1998

Influence of the Ah locus on the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the hepatic epidermal growth factor receptor

scientific article published on 01 March 1991

Informing 21st-Century Risk Assessments with 21st-Century Science

scientific article published on April 2016

Inhibition of 2-fluorenamine-induced mutagenesis in Salmonella typhimurium by vitamin A

scientific article published on October 1, 1979

Inhibition of high-density growth arrest in human squamous carcinoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

scientific article published in August 1990

Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals

scientific article published on 19 January 2005

Interactive effects between 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,2',4,4',5,5'-hexachlorobiphenyl in female B6C3F1 mice: tissue distribution and tissue-specific enzyme induction

scientific article published on 01 November 1996

Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.

scientific article published in September 1994

Intersection of systematic review methodology with the NIH reproducibility initiative

scientific article

Intestinal absorption of two glucose analogues in rats of different ages

scientific article published on 01 January 1987

Is Supersize More than Just Too Much Food?

scientific article published on June 1, 2012

Lack of correlation between sensitivity to growth inhibition and receptor number for transforming growth factor beta in human squamous carcinoma cell lines

scientific article published on 01 June 1989

Laser Doppler measurements of cutaneous blood flow in ageing mice and rats

scientific article published on August 1, 1991

Leading the world's premier environmental health organization: a message from Linda Birnbaum

scientific article published on April 2009

Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research

scientific article

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Limited PCB antagonism of TCDD-induced malformations in mice

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Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice.

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Maturational changes in dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Fischer 344 rats

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Naturally complex: Perspectives and challenges associated with Botanical Dietary Supplement Safety assessment.

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Novel and distinct metabolites identified following a single oral dose of α- or γ-hexabromocyclododecane in mice

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Polybrominated diphenyl ether (PBDE) levels in an expanded market basket survey of U.S. food and estimated PBDE dietary intake by age and sex.

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Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener.

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Prepubertal serum concentrations of organochlorine pesticides and age at sexual maturity in Russian boys

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Proposed mechanistic description of dose-dependent BDE-47 urinary elimination in mice using a physiologically based pharmacokinetic model.

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Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation.

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Relative toxicity and tumor-promoting ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,4,7,8-pentachlorodibenzofuran (PCDF), and 1,2,3,4,7,8-hexachlorodibenzofuran (HCDF) in hairless mice

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Retinoic acid-induced alterations in the expression of growth factors in embryonic mouse palatal shelves.

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Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

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Role of transforming growth factor beta in the proliferative effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on human squamous carcinoma cells

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S-phenylcysteine formation in hemoglobin as a biological exposure index to benzene

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Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here

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Senescence-associated decline in hepatic peroxisomal enzyme activities corresponds with diminished levels of retinoid X receptor alpha, but not peroxisome proliferator-activated receptor alpha

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Senescent changes in rodent hepatic epoxide metabolism

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Serum Metabolomic Profiles in Neonatal Mice following Oral Brominated Flame Retardant Exposures to Hexabromocyclododecane (HBCD) Alpha, Gamma, and Commercial Mixture

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Serum polychlorinated biphenyls and leukocyte telomere length in a highly-exposed population: The Anniston Community Health Survey.

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Species differences in the distribution of inhaled butadiene in tissues

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Species differences in the metabolism and disposition of inhaled 1,3-butadiene and isoprene.

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Subcellular localization of TCDD differs between the liver, lungs, and kidneys after acute and subchronic exposure: species/dose comparisons and possible mechanism

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Subchronic Exposure of [3H]- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: relationship of steady-state levels to disposition and metabolism.

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Subchronic/chronic toxicity of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) in rats. Part I. Design, general observations, hematology, and liver concentrations

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Subchronic/chronic toxicity of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) in rats. Part II. Biochemical effects.

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Subchronic/chronic toxicity of a mixture of four chlorinated dibenzo-p-dioxins in rats. II. Biochemical effects.

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Synergistic interaction of 2,3,7,8,-tetrachlorodibenzo-p-dioxin and hydrocortisone in the induction of cleft palate in mice.

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Synthetic Chemicals and Cardiometabolic Health Across the Life Course Among Vulnerable Populations: a Review of the Literature from 2018 to 2019

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TBBPA disposition and kinetics in pregnant and nursing Wistar Han IGS rats

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TCDD alters medial epithelial cell differentiation during palatogenesis

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TCDD alters the extracellular matrix and basal lamina of the fetal mouse kidney

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TCDD exposure of human embryonic palatal shelves in organ culture alters the differentiation of medial epithelial cells.

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TCDD-Induced hyperplasia of the ureteral epithelium produces hydronephrosis in murine fetuses

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TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD

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TCDD-mediated oxidative stress in male rat pups following perinatal exposure.

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TITLE Disposition and kinetics of Tetrabromobisphenol A in female Wistar Han rats

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Tackling the research challenges of health and climate change

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Telomeres as targets for the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) in rats

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Temporal trends in serum concentrations of polychlorinated dioxins, furans, and PCBs among adult women living in Chapaevsk, Russia: a longitudinal study from 2000 to 2009

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Teratogenic effects of 2,3,7,8-tetrabromodibenzo-p-dioxin and three polybrominated dibenzofurans in C57BL/6N mice

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Teratogenic effects of polychlorinated dibenzofurans in combination in C57BL/6N mice

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Teratogenic potency of TCDD, TCDF and TCDD-TCDF combinations in C57BL/6N mice

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Teratogenicity of three polychlorinated dibenzofurans in C57BL/6N mice

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Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier

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The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds

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The Epidemiologic Silver Lining of Climate Change.

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The GuLF STUDY: A Prospective Study of Persons Involved in the Deepwater Horizon Oil Spill Response and Clean-Up

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The Influence of Obesity on the Pharmacokinetics of Dioxin in Mice: An Assessment Using Classical and PBPK Modeling

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The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium

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The National Toxicology Program Web-based nonneoplastic lesion atlas: a global toxicology and pathology resource

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The Office of Health Assessment and Translation: a problem-solving resource for the National Toxicology Program.

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The acute toxicity of 2,3,4,7,8-pentachlorodibenzofuran (4PeCDF) in the male Fischer rat

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The biochemical toxicity of perfluorodecanoic acid in the mouse is different from that of 2,3,7,8-tetrachlorodibenzo-p-dioxin

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The biological fate of decabromodiphenyl ethane following oral, dermal or intravenous administration.

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The effect of age on the glucuronidation and toxicity of 4,4'-thiobis(6-t-butyl-m-cresol)

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The effect of dose on 2,3,7,8-TCDD tissue distribution, metabolism and elimination in CYP1A2 (-/-) knockout and C57BL/6N parental strains of mice.

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The effect of dose, dose rate, route of administration, and species on tissue and blood levels of benzene metabolites

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The effect of environmental chemicals on human health

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The effects of 2,2',4,4',5,5'-hexachlorobiphenyl cotreatment on the disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

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The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the hepatic estrogen and glucocorticoid receptors in congenic strains of Ah responsive and Ah nonresponsive C57BL/6J mice

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The effects of TCDD on receptors for epidermal growth factor, glucocorticoid, and estrogen in Ah-responsive and -nonresponsive congenic mice and the effects of TCDD on estradiol metabolism in a liver tumor promotion model in female rats

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The fate of inhaled azodicarbonamide in rats

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The fate of β-hexabromocyclododecane in female C57BL/6 mice

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The influence of aging on intestinal absorption of TCDD in rats

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The mechanism of dioxin toxicity: relationship to risk assessment

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Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing long-evans rats following subchronic exposure.

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Tissue distribution of polybrominated diphenyl ethers in male rats and implications for biomonitoring.

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Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife

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Toxic interaction of specific polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin: increased incidence of cleft palate in mice

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Toxicity and disposition of 2,3,4,7,8-pentachlorodibenzofuran (4PeCDF) in the Rhesus monkey (Macaca mulatta)

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Toxicity and distribution of 2,3,7,8-tetrachlorodibenzofuran in male guinea pigs.

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Toxicity equivalency factors for PCBs?

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Toxicokinetics of BDE 47 in female mice: effect of dose, route of exposure, and time

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Toxicokinetics of inhaled 1,3-butadiene in monkeys: comparison to toxicokinetics in rats and mice

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Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice.

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Toxicokinetics of the flame retardant hexabromocyclododecane alpha: effect of dose, timing, route, repeated exposure, and metabolism

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Toxicokinetics of the flame retardant hexabromocyclododecane gamma: effect of dose, timing, route, repeated exposure, and metabolism

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Updating the NIEHS Strategic Plan.

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Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic

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Uptake of vinylidene fluoride in rats simulated by a physiological model

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Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550.

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Use of a physiologically based pharmacokinetic model for rats to study the influence of body fat mass and induction of CYP1A2 on the pharmacokinetics of TCDD.

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Use of toxic equivalency factors for risk assessment for dioxins and related compounds.

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