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List of works by Mien-Chie Hung

14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition

scientific article

14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival.

scientific article published on 24 March 2009

14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2

scientific article

A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer

scientific article published on June 2016

A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.

scientific article published on 23 January 2017

A chirality-dependent action of vitamin C in suppressing Kirsten rat sarcoma mutant tumor growth by the oxidative combination: Rationale for cancer therapeutics

scientific article published on 08 October 2019

A delayed chemically induced tumorigenesis in Brca2 mutant mice

scientific article published in March 2004

A flow-proteometric platform for analyzing protein concentration (FAP): Proof of concept for quantification of PD-L1 protein in cells and tissues

scientific article published on 29 May 2018

A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing.

scientific article published on 26 January 2018

A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells

scientific article published on April 2005

A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis

scientific article published on 05 December 2016

A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.

scientific article published on 4 April 2016

A new fork for clinical application: targeting forkhead transcription factors in cancer

scientific article

A new mutational AKTivation in the PI3K pathway

scientific article published on August 2007

A new role of protein phosphatase 2a in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells

scientific article published on September 2004

A novel CRM1-dependent nuclear export signal in adenoviral E1A protein regulated by phosphorylation

scientific article published on 25 October 2006

A novel hTERT promoter-driven E1A therapeutic for ovarian cancer.

scientific article published on 11 August 2009

A novel ligand-receptor relationship between families of ribonucleases and receptor tyrosine kinases

scientific article published on 19 November 2018

A tumor vessel-targeting fusion protein elicits a chemotherapeutic bystander effect in pancreatic ductal adenocarcinoma

scientific article published on March 2017

ADAM9 promotes lung cancer metastases to brain by a plasminogen activator-based pathway

scientific article

ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis

scientific article published on 01 March 2020

AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model

scientific article

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation

scientific article published on 12 January 2016

APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis

scientific article

APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis

ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway

scientific article

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.

scientific article

Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis

scientific article published on 15 April 2015

Aberrant expression of the c-erbB-2/neu protooncogene in ovarian cancer

scientific article published on January 10, 1992

Abstract LB-119: Single-cell live imaging of paclitaxel-resistant cancer cell generation

article by Na Niu et al published 15 July 2016 in Cancer Research

Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors

scientific article

Actin cytoskeleton remodeling drives epithelial-mesenchymal transition for hepatoma invasion and metastasis

scientific article published on 23 November 2017

Activation of Aurora A kinase increases YAP stability via blockage of autophagy

scientific article published on 03 June 2019

Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer

scientific article

Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells

scientific article

Activation of murine double minute 2 by Akt in mammary epithelium delays mammary involution and accelerates mammary tumorigenesis.

scientific article

Activation of p21(CIP1/WAF1) in mammary epithelium accelerates mammary tumorigenesis and promotes lung metastasis

scientific article

Activation of phagocytosis by immune checkpoint blockade

scientific article published on 30 July 2018

Adenoviral E1A targets Mdm4 to stabilize tumor suppressor p53

scientific article

Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation ⬇️

scientific article published on August 2, 2010

Adenovirus type 5 E1A sensitizes hepatocellular carcinoma cells to gemcitabine ⬇️

scientific article published on October 1, 2003

Advances in targeting IKK and IKK-related kinases for cancer therapy

scientific article published on September 2008

Advances in targeting human epidermal growth factor receptor-2 signaling for cancer therapy

scientific article published on November 2006

Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis

scientific article published in January 2002

Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3

scientific article

All roads lead to mTOR: integrating inflammation and tumor angiogenesis

scientific article published on 20 September 2007

An essential role of PRMT1-mediated EGFR methylation in EGFR activation by ribonuclease 5

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

scientific article published on August 2008

Analysis of Individual Signaling Complexes by mMAPS, a Flow-Proteometric System.

scientific article published on April 2016

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer.

scientific article published on 29 March 2018

Antitumor Agents. 282. 2′-(R)-O-Acetylglaucarubinone, a Quassinoid from Odyendyea gabonensis As a Potential Anti-Breast and Anti-Ovarian Cancer Agent ⬇️

scientific article published on September 24, 2010

Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1.

scientific article published on September 2006

Arginine methylation of EGFR: a new biomarker for predicting resistance to anti-EGFR treatment

scientific article published in December 2017

Argininosuccinate synthetase 1 (ASS1) is a common metabolic marker of chemosensitivity for targeted arginine- and glutamine-starvation therapy.

scientific article

Arrest-defective-1 protein (ARD1): tumor suppressor or oncoprotein?

scientific article

Assessing metastatic potential of breast cancer cells based on EGFR dynamics

scientific article published on 04 March 2019

Association between ductal fluid proteomic expression profiles and the presence of lymph node metastases in women with breast cancer

Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy

scientific article

Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2.

scientific article

Author Correction: A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis

scientific article published on 05 June 2020

Author Correction: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

scientific article published on 29 January 2020

Author Correction: PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

scientific article published on 08 October 2020

Automated electrorotation to reveal dielectric variations related to HER-2/neu overexpression in MCF-7 sublines.

scientific article published on February 2002

BAP1 links metabolic regulation of ferroptosis to tumour suppression

scientific article published on 10 September 2018

BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress

scientific article published on 06 August 2019

Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model

scientific article published on September 2005

Beyond NF-κB activation: nuclear functions of IκB kinase α

scientific article

Beyond anti-VEGF: dual-targeting antiangiogenic and antiproliferative therapy

scientific article published on 24 May 2013

BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment

scientific article

Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.

scientific article published on April 2008

Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2

scientific article

Biochemical fractionation of membrane receptors in the nucleus.

scientific article published in January 2015

Block-Cell-Printing for live single-cell printing

scientific article

Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.

scientific article

Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer

scientific article published on 01 February 2020

Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors

scientific article published on 18 January 2016

Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases

scientific article published on 01 May 2020

Breast cancer brain metastases

scientific article published on December 2007

Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR ⬇️

scientific article published on January 9, 2012

CARMA3 is crucial for EGFR-Induced activation of NF-κB and tumor progression

scientific article

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

scientific article

CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

scientific article published on 08 November 2019

CDK4/6 inhibitors in hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer: Are we at the finish line?

CHM-1 induces apoptosis via p38-mediated upregulation of DR5 expression in human ovarian cancer SKOV3 cells

scientific article published on 3 September 2011

COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport

scientific article

CXCR4 expression in early breast cancer and risk of distant recurrence

scientific article published on 25 November 2009

Cancer Cell Metabolism Bolsters Immunotherapy Resistance by Promoting an Immunosuppressive Tumor Microenvironment

scientific article published on 22 July 2020

Cancer-specific activation of the survivin promoter and its potential use in gene therapy

scientific article

Cancer-specific gene therapy.

scientific article

Cancer-targeted BikDD gene therapy elicits protective antitumor immunity against lung cancer

scientific article published on 31 January 2011

Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo

scientific article published on 15 November 2015

Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells.

scientific article published on 23 January 2013

Ceramide does not act as a general second messenger for ultraviolet-induced apoptosis

scientific article published in January 2002

Characterization of a novel tripartite nuclear localization sequence in the EGFR family

scientific article published on 5 February 2007

Chemosensitization of HER-2/neu-overexpressing human breast cancer cells to paclitaxel (Taxol) by adenovirus type 5 E1A ⬇️

scientific article published on August 18, 1997

Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-kappaB expression

scientific article published on 01 June 2007

Co-regulation of B-Myb expression by E2F1 and EGF receptor

scientific article

Conformational stability of a snake cardiotoxin

scientific article published on 01 October 1977

Controlled Extracellular Matrix Degradation in Breast Cancer Tumors Improves Therapy by Trastuzumab ⬇️

scientific article published on November 16, 2010

Corrigendum: Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors.

scientific article published in October 2016

Cross-reactivity of C219 Anti-p170mdr-1 Antibody With p185c-erbB2 in Breast Cancer Cells: Cautions on Evaluating p170mdr-1 ⬇️

scientific article published on October 15, 1997

Crossregulation of NF-kappaB by the APC/GSK-3beta/beta-catenin pathway

scientific article published on March 2004

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation

scientific article

Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis

scientific article

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification

scientific article

Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer

scientific article

Cytoplasmic expression of p21CIP1/WAF1 is correlated with IKKbeta overexpression in human breast cancers

scientific article published on 01 November 2006

De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells

scientific article

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.

scientific article published on 11 April 2010

Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancer

scientific article

Deglycosylation of PD-L1 by 2-deoxyglucose reverses PARP inhibitor-induced immunosuppression in triple-negative breast cancer

scientific article published on 01 September 2018

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

scientific article published on 26 March 2007

Delivery of DNA to tumor cells using cationic liposomes

scientific article published on 01 January 2004

Determinants of rapamycin sensitivity in breast cancer cells

scientific article published on February 2004

Deubiquitination and Stabilization of PD-L1 by CSN5.

scientific article published on 14 November 2016

Deubiquitylation and stabilization of PTEN by USP13

scientific article

Dicer Elicits Paclitaxel Chemosensitization and Suppresses Cancer Stemness in Breast Cancer by Repressing AXL.

scientific article published on 23 May 2016

Different restriction enzyme-generated sticky DNA ends can be joinedin vitro ⬇️

scientific article published on February 24, 1984

Differential expression of the neu oncogene in mouse liver and pancreatic cell lines

scientific article published on July 15, 1992

Digital Receptor Occupancy Assay in Quantifying On- and Off-Target Binding Affinities of Therapeutic Antibodies ⬇️

scientific article published on 19 February 2020

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

scientific article published on 22 March 2019

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

scientific article published on August 2008

Downregulation of microRNA miR-520h by E1A contributes to anticancer activity

scientific article

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

scientific article

Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase

scientific article

Dysregulation of cellular signaling by HER2/neu in breast cancer

scientific article (publication date: October 2003)

Dysregulation of microRNAs in cancer

scientific article published on 17 October 2012

E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation

scientific article

E1A-Mediated Inhibition of HSPA5 Suppresses Cell Migration and Invasion in Triple-Negative Breast Cancer

E1A-mediated inhibition of HSPA5 suppresses cell migration and invasion in triple-negative breast cancer

article by Hsin-An Chen et al published March 2015 in Annals of Surgical Oncology

EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape

scientific article published on 12 January 2016

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

scientific article published on 20 December 2018

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. ⬇️

scientific article published on May 2013

EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization.

scientific article

EGFR-SGLT1 interaction does not respond to EGFR modulators, but inhibition of SGLT1 sensitizes prostate cancer cells to EGFR tyrosine kinase inhibitors

scientific article published on 14 June 2013

ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.

scientific article

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

scientific article published on 20 January 2008

EZH2 Regulates Neuronal Differentiation of Mesenchymal Stem Cells through PIP5K1C-dependent Calcium Signaling ⬇️

scientific article published on January 7, 2011

EZH2 expression correlates with locoregional recurrence after radiation in inflammatory breast cancer.

scientific article published on 23 July 2014

EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling

scientific article

EZH2: a pivotal regulator in controlling cell differentiation ⬇️

scientific article published on October 10, 2012

Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells

scientific article

Emerging molecular targets in esophageal cancers

scientific article published on January 2007

Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth

scientific article

Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor

scientific article

Endostatin-cytosine deaminase fusion protein suppresses tumor growth by targeting neovascular endothelial cells

scientific article published on January 2006

Endothelial p130cas confers resistance to anti-angiogenesis therapy

scientific article published on 01 January 2022

Enhanced paclitaxel cytotoxicity and prolonged animal survival rate by a nonviral-mediated systemic delivery of E1A gene in orthotopic xenograft human breast cancer

scientific article

Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells

scientific article published in October 2002

Enhancement of Bik antitumor effect by Bik mutants

scientific article published on November 2003

Enhancer of Zeste Homolog 2 and Histone Deacetylase 9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes

scientific article published on 2 June 2016

Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer

scientific article published on 10 March 2022

Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression

scientific article published on October 2007

Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer

scientific article

Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1

scientific article

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.

scientific article published in February 2018

ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells

scientific article

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

scientific article published in July 2005

Erratum to: E1A-Mediated Inhibition of HSPA5 Suppresses Cell Migration and Invasion in Triple-Negative Breast Cancer

scientific article published on 3 February 2017

Erratum: Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells

scientific article published on 22 December 2016

Erratum: The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer

scientific article published on 01 October 2020

Erythropoietin Stimulates Tumor Growth via EphB4.

scientific article published on 14 October 2015

Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.

scientific article published on 27 April 2018

Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis

scientific article published on 24 May 2013

Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth

scientific article published on 29 June 2018

Expanding the arsenal: metformin for the treatment of triple-negative breast cancer?

scientific article

Exploiting induced vulnerability to overcome PARPi resistance and clonal heterogeneity in BRCA mutant triple-negative inflammatory breast cancer

scientific article published on 15 January 2022

Expression and Clinical Significance of Protein Kinase RNA-Like Endoplasmic Reticulum Kinase and Phosphorylated Eukaryotic Initiation Factor 2α in Pancreatic Ductal Adenocarcinoma

scientific article published on 01 March 2019

Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer

scientific article published on 02 July 2018

Expression of PEA3 and lack of correlation between PEA3 and HER-2/neu expression in breast cancer

scientific article published on 03 June 2006

Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

scientific article

Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix.

scientific article published on 02 September 2013

Expression profile of tyrosine kinases in breast cancer.

scientific article published in February 2002

External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator

scientific article

Extracellular PKM2 induces cancer proliferation by activating the EGFR signaling pathway

scientific article published on 15 February 2016

FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer

scientific article

FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization

scientific article published on 12 September 2011

Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells

scientific article

Functional roles of the human ribonuclease A superfamily in RNA metabolism and membrane receptor biology

scientific article published on 25 March 2019

Further evidence for expression and function of the VEGF-C/VEGFR-3 axis in cancer cells.

scientific article published in June 2008

GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.

scientific article published on 02 August 2016

Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.

scientific article published on 22 May 2014

Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues

scientific article

Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation

scientific article published on 02 October 2018

Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy

scientific article published on 21 January 2009

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.

scientific article published on 30 August 2016

H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism

scientific article published on 08 April 2019

HER family kinase domain mutations promote tumor progression and can predict response to treatment in human breast cancer ⬇️

scientific article published on 11 November 2014

HER-2/Neu signaling and therapeutic approaches in breast cancer.

scientific article

HER-2/neu Oncogene Characterization in Head and Neck Squamous Cell Carcinoma ⬇️

scientific article published on November 1, 1995

HER-2/neu-targeting gene therapy-a review ⬇️

scientific article published on June 14, 1995

HER2/neu in the management of invasive breast cancer

scientific article

HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis.

scientific article published on 18 December 2017

Hepatitis B virus X protein induces IKKα nuclear translocation via Akt-dependent phosphorylation to promote the motility of hepatocarcinoma cells

scientific article published on April 2012

Hepatoma cell-intrinsic TLR9 activation induces immune escape through PD-L1 upregulation in hepatocellular carcinoma

scientific article published on 17 May 2020

Her2 Neu overexpression counteracts the growth effects of C-myc in breast-cancer cells ⬇️

scientific article published on 01 April 1994

Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells

scientific article published in August 2002

High RPS3A expression correlates with low tumor immune cell infiltration and unfavorable prognosis in hepatocellular carcinoma patients

scientific article published on 01 September 2020

High speed digital protein interaction analysis using microfluidic single molecule detection system

scientific article published on 24 May 2010

Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties

scientific article published on 6 June 2014

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

scientific article published on 13 May 2021

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

scientific article

IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.

scientific article published on November 2008

IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression

scientific article published on 22 December 2011

IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

scientific article published on 15 July 2019

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

scientific article

Improved peak detection and quantification of mass spectrometry data acquired from surface-enhanced laser desorption and ionization by denoising spectra with the undecimated discrete wavelet transform

scientific article

Induction of Akt activity by chemotherapy confers acquired resistance

scientific article published on March 2009

Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8+ T Cells and Histone Acetyltransferases

scientific article published on 21 February 2017

Inhibition of ATR downregulates PD-L1 and sensitizes tumor cells to T cell-mediated killing

scientific article published on 01 July 2018

Inhibition of CDK2 reduces EZH2 phosphorylation and reactivates ERα expression in high-grade serous ovarian carcinoma

scientific article published on 01 April 2020

Inhibition of Nuclear Factor-κB Activity Is Involved in E1A-mediated Sensitization of Radiation-induced Apoptosis ⬇️

scientific article published on December 26, 1997

Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis

scientific article published on 10 August 2016

Inhibition of c-MET upregulates PD-L1 expression in lung adenocarcinoma

scientific article published on 01 February 2020

Inhibition of cancer cell growth by BRCA2.

scientific article published on March 2002

Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis

scientific article

Interaction between the Adhesion Receptor, CD44, and the Oncogene Product, p185 , Promotes Human Ovarian Tumor Cell Activation ⬇️

scientific article published on October 31, 1997

Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer

scientific article

Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin

scientific article published on October 2008

Intracaecal Orthotopic Colorectal Cancer Xenograft Mouse Model

scientific article published in June 2017

Involvement of cdc2-mediated phosphorylation in the cell cycle-dependent regulation of p185neu ⬇️

scientific article published on November 27, 1997

JAK2-binding long noncoding RNA promotes breast cancer brain metastasis

scientific article published on 13 November 2017

JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis.

scientific article published on 08 January 2016

JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression

scientific article published on 23 January 2017

Juxtacrine signaling inhibits antitumor immunity by upregulating PD-L1 expression.

scientific article

KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.

scientific article

KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta

scientific article published on October 2009

KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

scientific article

Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion

scientific article (publication date: August 2007)

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

scientific article published on 23 September 2012

Lapatinib-mediated cyclooxygenase-2 expression via epidermal growth factor receptor/HuR interaction enhances the aggressiveness of triple-negative breast cancer cells

scientific article published on 25 January 2013

Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFa-induced apoptosis

scientific article published in Journal of Biological Chemistry

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition

scientific article published on 10 January 2019

Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer ⬇️

scientific article published on April 8, 2012

Long noncoding RNA MALAT1 suppresses breast cancer metastasis

scientific article published on 22 October 2018

Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast.

scientific article published on December 2003

Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers

scientific article published on September 2008

Lymphotoxin-β Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer.

scientific article published on 14 February 2017

MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation

scientific article

MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer

scientific article

MEASUREMENT of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS).

scientific article published on October 2010

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1

scientific article published on 31 January 2019

MRNIP condensates promote DNA double-strand break sensing and end resection

scientific article published on 12 May 2022

Mechanisms Controlling PD-L1 Expression in Cancer

scientific article published on 24 October 2019

Mechanisms of deregulated her2/neu expression in breast-cancer cell-lines ⬇️

scientific article published on March 1, 1994

Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer

scientific article

Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death

scientific article published on May 2007

Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.

scientific article

Metastasis regulation by PPARD expression in cancer cells.

scientific article published on 12 January 2017

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

scientific article published on 17 December 2020

Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer

scientific article

MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis.

scientific article

Microfluidic three-dimensional hydrodynamic flow focusing for the rapid protein concentration analysis

scientific article

Mitosis-specific Negative Regulation of Epidermal Growth Factor Receptor, Triggered by a Decrease in Ligand Binding and Dimerization, Can Be Overcome by Overexpression of Receptor ⬇️

scientific article published on July 25, 1997

Modeling familial cancer with induced pluripotent stem cells

scientific article

Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.

scientific article

Molecular mechanisms in Barrett's metaplasia and its progression.

scientific article published in April 2007

Molecular predictors of response to trastuzumab and lapatinib in breast cancer.

scientific article published on 22 December 2009

Molecular profile of advanced-stage transitional cell carcinoma of the ovary ⬇️

scientific article published on July 1, 1997

Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma

scientific article published on 24 February 2017

Mutant LKB1 Confers Enhanced Radiosensitization in Combination with Trametinib in KRAS-Mutant Non-Small Cell Lung Cancer

scientific article published on 01 August 2018

Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

scientific article published on 10 May 2007

Myocyte Enhancer Factor-2 Interacting Transcriptional Repressor (MITR) Is a Switch That Promotes Osteogenesis and Inhibits Adipogenesis of Mesenchymal Stem Cells by Inactivating Peroxisome Proliferator-activated Receptor γ-2 ⬇️

scientific article published on January 19, 2011

Nanoparticle Delivery of miR-34a Eradicates Long-term-cultured Breast Cancer Stem Cells via Targeting C22ORF28 Directly

scientific article published on 17 October 2017

New Approaches on Cancer Immunotherapy

scientific article published on 15 October 2019

Non-canonical signaling mode of the epidermal growth factor receptor family

scientific article

Novel approaches for chemosensitization of breast cancer cells: the E1A story

scientific article published on January 2007

Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.

scientific article published on January 2005

Novel targets of Akt, p21(Cipl/WAF1), and MDM2.

scientific article

Nuclear EGFR is required for cisplatin resistance and DNA repair

scientific article published on 8 March 2009

Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes

scientific article

Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

scientific article published on July 2009

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family ⬇️

scientific article published on April 20, 2012

Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway

scientific article published on June 2005

Nuclear receptor tyrosine kinase transport and functions in cancer

scientific article published on 13 June 2020

Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells

scientific article

Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors

scientific article published on 27 October 2009

Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis

scientific journal article

Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1.

scientific article published on August 2006

On Mammary Gland Growth Factors: Roles in Normal Development and in Cancer ⬇️

scientific article published on August 1, 2012

Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation

scientific article published on 6 October 2016

Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression

scientific article published on 03 June 2019

Overexpression of both p185c-erbB2 and p170mdr-1 renders breast cancer cells highly resistant to taxol ⬇️

scientific article published on April 23, 1998

Overexpression of the c-erbB-2/neu-encoded p185 protein in primary lung cancer

scientific article published on January 1, 1992

Oxygen sensor boosts growth factor signaling

scientific article published in March 2009

P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells.

scientific article published on June 2004

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression.

scientific article published on 6 February 2017

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

scientific article published on 14 September 2020

POMC maintains tumor-initiating properties of tumor tissue-derived long-term-cultured breast cancer stem cells

scientific article published on 18 February 2017

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

scientific article published on 16 November 2015

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

scientific article

PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease

scientific article published on 11 February 2019

Palmitoylation stabilizes PD-L1 to promote breast tumor growth

scientific article published on 04 December 2018

Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression ⬇️

scientific article

Pharmacological suppression of B7-H4 glycosylation restores antitumor immunity in immune-cold breast cancers

scientific article published on 16 September 2020

Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation

scientific article

Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB

scientific article published on April 2007

Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers.

scientific article

Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

scientific article published in January 2018

Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis.

scientific article published in May 2002

Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients.

scientific article published on June 2004

Physiological regulation of Akt activity and stability.

scientific article

Pneumatically Actuated Soft Micromold Device for Fabricating Collagen and Matrigel Microparticles

scientific article published on 27 June 2017

Posttranslational Modifications of PD-L1 and Their Applications in Cancer Therapy

scientific article published on 01 November 2018

Potential natural products that target the SARS-CoV-2 spike protein identified by structure-based virtual screening, isothermal titration calorimetry and lentivirus particles pseudotyped (Vpp) infection assay

scientific article published on 16 September 2021

Powering Tumor Metastasis with Recycled Fuel

scientific article published in September 2016

Proapoptotic and antitumor activities of adenovirus-mediated p202 gene transfer

scientific article published in October 2002

Prostate-specific antitumor activity by probasin promoter-directed p202 expression.

scientific article

Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases

scientific article

Quality control and peak finding for proteomics data collected from nipple aspirate fluid by surface-enhanced laser desorption and ionization

scientific article

RAC1 activation mediates Twist1-induced cancer cell migration

scientific article

RASAL2: wrestling in the combat of Ras activation

scientific article published on 01 September 2013

RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus

scientific article

RTRB-10TYROSINE KINASE RECEPTOR TIE2 REGULATES DNA REPAIR THROUGH THE PROTO-ONCOGENE ABL1 IN BRAIN TUMOR STEM CELLS.

scientific article

Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer

scientific article

Rapamycin regulates the phosphorylation of rictor

scientific article published on 8 August 2007

Rapid detection of two-protein interaction with a single fluorophore by using a microfluidic device

scientific article

Rational combination of immunotherapy for triple negative breast cancer treatment

scientific article published in October 2017

Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis ⬇️

scientific article published on April 9, 1998

Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation

scientific article

Regulation of breast cancer metastasis by atypical chemokine receptors

scientific article published on 21 April 2009

Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling

scientific article

Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis

scientific article published in October 2003

Regulation of therapeutic resistance in cancers by receptor tyrosine kinases

scientific article published on 15 March 2016

Regulation of tumor angiogenesis by EZH2.

scientific article

Regulation of ubiquitination-mediated protein degradation by survival kinases in cancer

scientific article

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

scientific article published on 18 July 2019

Repression of neu-induced clonogenicity by dimethylsulfoxide correlates with decreased levels of neu-encoded cell-surface p185 and changes in phosphotyrosine content of endogenous proteins ⬇️

scientific article published on January 15, 1993

Retracted: Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

retracted article

Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma

scientific article published on 05 October 2020

Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis.

scientific article published in September 2002

Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity

scientific article

SLFN11 inhibits hepatocellular carcinoma tumorigenesis and metastasis by targeting RPS4X via mTOR pathway

scientific article published on 25 March 2020

STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis

scientific article published on January 2004

STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.

scientific article

Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis

scientific article published on 22 March 2016

Selective activation of ceruloplasmin promoter in ovarian tumors: potential use for gene therapy

scientific article published on March 2004

Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells

scientific article published on 15 November 2015

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death

scientific article published on 11 December 2019

Severe Hepatitis Promotes Hepatocellular Carcinoma Recurrence via NF-κB Pathway-Mediated Epithelial-Mesenchymal Transition after Resection

scientific article published on 11 December 2015

Signaling-mediated regulation of MicroRNA processing

scientific article

Significant differences in nipple aspirate fluid protein expression between healthy women and those with breast cancer demonstrated by time-of-flight mass spectrometry

scientific article

Single oral dose acute and subacute toxicity of a c-MET tyrosine kinase inhibitor and CDK 4/6 inhibitor combination drug therapy

scientific article published in January 2018

Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation

scientific article published on 01 November 2020

Strategies to target HER2/neu overexpression for cancer therapy

scientific article

Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

scientific article published in November 2017

Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug

scientific article published on 01 August 2020

Suppressed autophosphorylation and tyrosine kinase-activity in revertant cell-lines expressing rat Neu oncogene ⬇️

scientific article published on September 1, 1994

Suppression of pancreatic tumor progression by systemic delivery of a pancreatic-cancer-specific promoter driven Bik mutant

scientific article published on 13 June 2005

Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma

scientific article published on 01 October 2018

Survival of cancer cells is maintained by EGFR independent of its kinase activity

scientific article

Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells

scientific article published on 16 June 2016

Synergism of PARP inhibitor fluzoparib (HS10160) and MET inhibitor HS10241 in breast and ovarian cancer cells

scientific article published on 01 March 2019

Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells

scientific article published in February 2006

Systemic gene therapy in human xenograft tumor models by liposomal delivery of the E1A gene.

scientific article published in November 2002

Systemic tumor suppression by the proapoptotic gene bik

scientific article (publication date: 2002)

TIE2 associates with caveolae and regulates caveolin-1 to promote their nuclear translocation

scientific article

TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1.

scientific article published on April 2016

TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase.

scientific article

TNFalpha induces HIF-1alpha expression through activation of IKKbeta

scientific article published on 17 September 2009

TRIM24 links a non-canonical histone signature to breast cancer

scientific article

TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer

scientific article published on 03 October 2020

Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling

scientific article published on 25 September 2019

Tannic acid suppresses SARS-CoV-2 as a dual inhibitor of the viral main protease and the cellular TMPRSS2 protease

scientific article published on 01 December 2020

Targeted BikDD expression kills androgen-dependent and castration-resistant prostate cancer cells.

scientific article

Targeted expression of BikDD combined with metronomic doxorubicin induces synergistic antitumor effect through Bax activation in hepatocellular carcinoma

scientific article

Targeted expression of BikDD eliminates breast cancer with virtually no toxicity in noninvasive imaging models.

scientific article

Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models

scientific article published on 01 July 2007

Targeted expression of miR-34a using the T-VISA system suppresses breast cancer cell growth and invasion

scientific article

Targeted hepatocellular carcinoma proapoptotic BikDD gene therapy ⬇️

scientific article published on December 13, 2010

Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model

scientific article

Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer

scientific article published on 01 December 2018

Targeting glycosylated PD-1 induces potent anti-tumor immunity

scientific article published on 10 March 2020

Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells

scientific article published in October 2004

Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression

scientific article published on 29 August 2020

Targeting the IKKβ/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer.

scientific article published on 23 July 2012

Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.

scientific article published on January 2011

The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells

scientific article published on 01 September 2018

The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1

scientific article published on 27 November 2020

The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines

scientific article published on 20 May 2010

The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells.

scientific article published on April 2004

The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer

scientific article

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

scientific journal article

The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors

scientific article published on 20 February 2017

The NH(2)-terminal and conserved region 2 domains of adenovirus E1A mediate two distinct mechanisms of tumor suppression

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

scientific article published on 08 November 2012

The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

scientific article

The VEGF-C/Flt-4 Axis Promotes Invasion and Metastasis of Cancer Cells

The VEGF-C/Flt-4 Axis Promotes Invasion and Metastasis of Cancer Cells

The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells

scientific article

The ZNF304-integrin axis protects against anoikis in cancer

scientific journal article

The adenoviral E1A induces p21WAF1/CIP1 expression in cancer cells

scientific article published in June 2003

The anti-tumor activity of E1A and its implications in cancer therapy

scientific article published on 07 February 2014

The crosstalk of mTOR/S6K1 and Hedgehog pathways

scientific article

The erbB2 gene as a cancer therapeutic target and the tumor- and metastasis-suppressing function of E1A

scientific article published on June 1, 1998

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

scientific article published on 08 April 2020

The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosis

scientific article published on 03 July 2020

The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin

scientific article published on 26 October 2020

The microfocus assay system (mfas) - a simple quantitative assay to identify inhibitory drugs targeted against specific oncogenes ⬇️

scientific article published on 01 January 1994

The potential role of YAP in Axl-mediated resistance to EGFR tyrosine kinase inhibitors

scientific article published on 01 December 2019

The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer

scientific article published on 2 December 2016

The role of PRMT1 in EGFR methylation and signaling in MDA-MB-468 triple-negative breast cancer cells

scientific article published on 22 June 2017

The role of amino functions in recombinant human tumor necrosis factor in expression of biological activity ⬇️

scientific article published on 01 January 1992

The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells

scientific article

The roles of EZH2 in cell lineage commitment ⬇️

scientific article published on April 21, 2011

The sequence of the Drosophila melanogaster gene for yolk protein 1 ⬇️

scientific article published on December 11, 1981

The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer

scientific article published on 01 August 2020

The status of tyrosyl residues in a Formosan cobra cardiotoxin ⬇️

scientific article published on August 21, 1978

The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.

scientific article

The suppression of colon cancer cell growth in nude mice by targeting beta-catenin/TCF pathway

scientific article published on November 2002

The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus

scientific article

Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells

scientific article published on 25 September 2019

Tid1, CHIP and ErbB2 interactions and their prognostic implications for breast cancer patients ⬇️

scientific article published on June 27, 2011

Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response

scientific article

Tyrosine phosphorylation controls PCNA function through protein stability

scientific article

Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin

scientific article

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

scientific article published on November 2004

Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway

scientific article published on May 2004

Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression

scientific article published on 02 May 2016

Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis

scientific article

YY1 and HDAC9c transcriptionally regulate p38-mediated mesenchymal stem cell differentiation into osteoblasts

scientific article published in March 2018

ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer ⬇️

scientific article published in April 2018

beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer

scientific article

beta-catenin nuclear localization is associated with grade in ovarian serous carcinoma

scientific article published on 01 March 2003

lncRNA directs cooperative epigenetic regulation downstream of chemokine signals

scientific article

mMAPS: a flow-proteometric technique to analyze protein-protein interactions in individual signaling complexes

scientific article

miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion

scientific article

miR326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression

scientific article published on 9 September 2014

miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin

scientific article

p53 acetylation is crucial for its transcription-independent proapoptotic functions

scientific article

p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.

scientific article

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