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List of works by David Leigh

A 3D Interlocked Structure from a 2D Template: Structural Requirements for the Assembly of a Square-Planar Metal-Coordinated[2]Rotaxane

scientific article published on 01 July 2004

A Catalytic Palladium Active-Metal Template Pathway to [2]Rotaxanes

scientific article published on 01 January 2007

A Chemically-Driven Molecular Information Ratchet

scientific article published on 18 January 2008

A Chiral Cyclometalated Iridium Star of David [2]Catenane

scientific article published on 05 January 2021

A Rotaxane-Based Switchable Organocatalyst

scientific article published on 13 April 2012

A Simple General Ligand System for Assembling Octahedral Metal–Rotaxane Complexes

scientific article published on 01 February 2004

A Solomon link through an interwoven molecular grid

scientific article published on 8 May 2015

A Star of David catenane

scientific article published on 21 September 2014

A Switchable [2]Rotaxane Asymmetric Organocatalyst That Utilizes an Acyclic Chiral Secondary Amine

scientific article published on 24 March 2014

A Three-Compartment Chemically-Driven Molecular Information Ratchet

scientific article published on 08 May 2012

A complementary pair of enantioselective switchable organocatalysts

scientific article published on 23 August 2017

A generic basis for some simple light-operated mechanical molecular machines

scientific article published in October 2004

A mechanically interlocked molecular system programmed for the delivery of an anticancer drug

scientific article published on 25 February 2015

A metal-complex-tolerant CuAAC ‘click’ protocol exemplified through the preparation of homo- and mixed-metal-coordinated [2]rotaxanes

scientific article published on 01 November 2007

A molecular information ratchet

scientific article

A molecular machine mimicking the ribosome: a molecule that makes molecules

scientific article published on 28 May 2013

A quantum-mechanical description of macrocyclic ring rotation in benzylic amide

scientific article published in April 2001

A reversible synthetic rotary molecular motor

scientific article published in November 2004

A rotaxane mimic of the photoactive yellow protein chromophore environment: effects of hydrogen bonding and mechanical interlocking on a coumaric amide derivative

scientific article published on 01 May 2007

A scalable synthesis of 5,5′-dibromo-2,2′-bipyridine and its stepwise functionalization via Stille couplings

A simple and highly effective ligand system for the copper(I)-mediated assembly of rotaxanes

scientific article published on 14 October 2014

A single synthetic small molecule that generates force against a load

scientific article

A small molecule that walks non-directionally along a track without external intervention

scientific article

A switchable palladium-complexed molecular shuttle and its metastable positional isomers

scientific article published on 9 November 2007

A synthetic molecular pentafoil knot

scientific article

A synthetic small molecule that can walk down a track

scientific article published on 20 December 2009

A tape-reading molecular ratchet ⬇️

scholarly article published in 2022

AAAA-DDDD quadruple hydrogen-bond arrays featuring NH···N and CH···N hydrogen bonds

scientific article published on 25 June 2013

AAA−DDD Triple Hydrogen Bond Complexes

scientific article published on 01 October 2009

Active Template Synthesis of Rotaxanes and Molecular Shuttles with Switchable Dynamics by Four-Component PdII-Promoted Michael Additions

article

Active metal template synthesis of [2]catenanes

scientific article published in November 2009

Active metal template synthesis of rotaxanes, catenanes and molecular shuttles

scientific article published on 16 April 2009

Active template rotaxane synthesis through the Ni-catalyzed cross-coupling of alkylzinc reagents with redox-active esters

scientific article published on 19 June 2019

Active-Metal Template Synthesis of a Molecular Trefoil Knot

scientific article published on 14 September 2011

Adsorption of Fumaramide [2]Rotaxane and Its Components on a Solid Substrate: A Coverage-Dependent Study

scientific article published on 01 August 2006

Allosteric initiation and regulation of catalysis with a molecular knot

scientific article

An AAAA–DDDD quadruple hydrogen-bond array

scientific article published on 01 March 2011

An Allosterically Regulated Molecular Shuttle

scientific article published on 01 February 2006

An Unusual Nickel−Copper-Mediated Alkyne Homocoupling Reaction for the Active-Template Synthesis of [2]Rotaxanes

scientific article published on 01 May 2010

An artificial molecular machine that builds an asymmetric catalyst

scientific article published on 2 April 2018

An autonomous chemically fuelled small-molecule motor

scientific article (publication date: 8 June 2016)

An ion-pair template for rotaxane formation and its exploitation in an orthogonal interaction anion-switchable molecular shuttle.

scientific article

Artificial Molecular Machines

scientific article

Artificial molecular motors

scientific article

Artificial switchable catalysts

scientific article published on 12 May 2015

Asymmetric Catalysis with a Mechanically Point-Chiral Rotaxane

scientific article published on 2 February 2016

Benzylic Imine Catenates: Readily Accessible Octahedral Analogues of the Sauvage Catenates

scientific article published on 17 April 2001

Beyond switches: ratcheting a particle energetically uphill with a compartmentalized molecular machine

scientific article published in March 2006

Bimodal dynamics of mechanically constrained hydrogen bonds revealed by vibrational photon echoes

article

Braiding a molecular knot with eight crossings.

scientific article

Cadiot–Chodkiewicz Active Template Synthesis of Rotaxanes and Switchable Molecular Shuttles with Weak Intercomponent Interactions ⬇️

scientific article published on 01 January 2008

Catalytic "active-metal" template synthesis of [2]rotaxanes, [3]rotaxanes, and molecular shuttles, and some observations on the mechanism of the cu(i)-catalyzed azide-alkyne 1,3-cycloaddition.

scientific article

Catalytic "click" rotaxanes: a substoichiometric metal-template pathway to mechanically interlocked architectures

scientific article published in February 2006

Catenanes: fifty years of molecular links

scientific article published on 07 May 2015

Chemoselective Formation of Successive Triazole Linkages in One Pot:  “Click−Click” Chemistry

scientific article published on 01 September 2006

Chiroptical Switching in a Bistable Molecular Shuttle

scientific article published on 01 November 2003

Comment on “Coordination-Driven Self-Assembly of a Molecular Knot Comprising Sixteen Crossings”

scientific article published on 27 August 2018

Complexation-Induced Translational Isomerism: Shuttling through Stepwise Competitive Binding

scientific article published on 01 December 2005

Conformational Flexibility of a Rotaxane Thread Probed by Electronic Spectroscopy in Helium Nanodroplets

scientific article published on 01 September 2009

Controlled Hydrogen-Bond Breaking in a Rotaxane by Discrete Solvation

scientific article published on 01 May 2010

Coordination Chemistry of a Molecular Pentafoil Knot

scientific article published on 20 February 2019

Coumaric amide rotaxanes: effects of hydrogen bonding and mechanical interlocking on the photochemistry and photophysics

article

Design, Synthesis, and Operation of Small Molecules That Walk along Tracks

scientific article published on 27 October 2010

Diels-Alder active-template synthesis of rotaxanes and metal-ion-switchable molecular shuttles

scientific article published in April 2010

Dissipative Catalysis with a Molecular Machine.

scientific article published on 20 May 2019

Dynamic Control of Chiral Space Through Local Symmetry Breaking in a Rotaxane Organocatalyst

scientific article published on 10 September 2019

Effects of knot tightness at the molecular level

scientific article

Efficient assembly of threaded molecular machines for sequence-specific synthesis

scientific article published on 7 April 2014

Electrochemically switchable hydrogen-bonded molecular shuttles

scientific article published in July 2003

En Route to a Molecular Sheaf: Active Metal Template Synthesis of a [3]Rotaxane with Two Axles Threaded through One Ring

scientific article published on 18 July 2011

Enhanced Hydrogen Bonding Induced by Optical Excitation: Unexpected Subnanosecond Photoinduced Dynamics in a Peptide-Based [2]Rotaxane

article

Entropy-Driven Translational Isomerism: A Tristable Molecular Shuttle

scientific article published on 01 January 2003

Enzyme-Mediated Directional Transport of a Small-Molecule Walker With Chemically Identical Feet.

scientific article published on August 2017

Experimental and theoretical study of the adsorption of fumaramide [2]rotaxane on Au(111) and Ag(111) surfaces

scientific article published in December 2005

Exploring the Activation Modes of a Rotaxane-Based Switchable Organocatalyst

scientific article published on 21 October 2014

Extremely Strong and Readily Accessible AAA−DDD Triple Hydrogen Bond Complexes

scientific article published on 01 January 2007

From catenanes to mechanically-linked polymers

From reactants to products via simple hydrogen-bonding networks: Information transmission in chemical reactions

scientific article

Genesis of the Nanomachines: The 2016 Nobel Prize in Chemistry

scientific article published on 20 October 2016

Getting harder: cobalt(III)-template synthesis of catenanes and rotaxanes

scientific article published in March 2009

Gold(I)-Template Catenane and Rotaxane Synthesis

scientific article published on 01 January 2008

Goldberg Active Template Synthesis of a [2]Rotaxane Ligand for Asymmetric Transition-Metal Catalysis

scientific article published on 16 June 2015

Half-rotation in a [2]catenane via interconvertible Pd(ii) coordination modes

scientific article published on 13 September 2005

Half-rotation in a kinetically locked [2]catenane induced by transition metal ion substitution

scientific article published on 09 May 2012

Hybrid organic–inorganic rotaxanes and molecular shuttles

scientific article published in Nature

Hydrogen bond-assembled fullerene molecular shuttle

scientific article published in March 2003

IR Spectroscopy on Jet-Cooled Isolated Two-Station Rotaxanes

scientific article published on 27 April 2011

Improved dynamics and positional bias with a second generation palladium(II)-complexed molecular shuttle

scientific article published on 5 March 2010

In trap fragmentation and optical characterization of rotaxanes

scientific article

Induction of motion in a synthetic molecular machine: effect of tuning the driving force

scientific article published on 5 April 2013

Information storage using supramolecular surface patterns

scientific article published in Science

Interlocked molecules: Linking rings without templates

scientific article published on 18 July 2010

Intermolecular aglycon transfer of ethyl 1-thiorhamnopyranosides under Koenigs—Knorr and Helferich glycosylation conditions

scientific article published on 01 October 1995

Knotting a molecular strand can invert macroscopic effects of chirality

scientific article published on 03 August 2020

Lanthanide Template Synthesis of Trefoil Knots of Single Handedness

scientific article published on 04 August 2015

Lanthanide Template Synthesis of a Molecular Trefoil Knot

scientific article published on 10 September 2014

Lighting up nanomachines

scientific article published in Nature

Light‐Driven Transport of a Molecular Walker in Either Direction along a Molecular Track ⬇️

scientific article published on January 3, 2011

Macroscopic transport by synthetic molecular machines.

scientific article published on 28 August 2005

Mechanically Linked Polycarbonate

scientific article published on 01 February 2003

Molecular Knots

scientific article published on 6 May 2017

Molecular Trefoil Knot from a Trimeric Circular Helicate

scientific article published on 20 March 2018

Molecular machines with bio-inspired mechanisms

scientific article published on 26 February 2018

Multistate photo-induced relaxation and photoisomerization ability of fumaramide threads: a computational and experimental study

scientific article

Nitrone [2]rotaxanes: simultaneous chemical protection and electrochemical activation of a functional group

scientific article published in July 2010

One Template, Multiple Rings: Controlled Iterative Addition of Macrocycles onto a Single Binding Site Rotaxane Thread

article

One-dimensional random walk of a synthetic small molecule toward a thermodynamic sink

scientific article

Operation mechanism of a molecular machine revealed using time-resolved vibrational spectroscopy

scientific article published in June 2010

Patterning through Controlled Submolecular Motion: Rotaxane-Based Switches and Logic Gates that Function in Solution and Polymer Films

article

Pentameric Circular Iron(II) Double Helicates and a Molecular Pentafoil Knot

scientific article published on 21 May 2012

Phosphorus-Based Functional Groups as Hydrogen Bonding Templates for Rotaxane Formation

scientific article published on 19 July 2011

Photoisomerization of a rotaxane hydrogen bonding template: light-induced acceleration of a large amplitude rotational motion

scholarly article

Pick-up, transport and release of a molecular cargo using a small-molecule robotic arm

scientific article (publication date: 21 December 2015)

Probing the Dynamics of the Imine-Based Pentafoil Knot and Pentameric Circular Helicate Assembly

article published in 2019

Probing the structure of a rotaxane with two-dimensional infrared spectroscopy

scientific article

Pyridyl-Acyl Hydrazone Rotaxanes and Molecular Shuttles.

scientific article

Rare and Diverse Binding Modes Introduced through Mechanical Bonding

scientific article published on 01 July 2005

Real-Time Fluctuations in Single-Molecule Rotaxane Experiments Reveal an Intermediate Weak Binding State during Shuttling

scientific article published on 08 January 2021

Reducing Molecular Shuttling to a Single Dimension

scientific article published in January 2000

Remarkable Positional Discrimination in Bistable Light- and Heat-Switchable Hydrogen-Bonded Molecular Shuttles

scientific article published on 01 May 2003

Rise of the Molecular Machines

scientific article published on 27 July 2015

Rotary and linear molecular motors driven by pulses of a chemical fuel.

scientific article published in October 2017

Rotaxane building blocks bearing blocked isocyanate stoppers: polyrotaxanes through post-assembly chain extension

scientific article published in July 2003

Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide

scientific article published on 01 January 2009

Rotaxanes of cyclic peptides

scientific article published in February 2006

Second generation specific-enzyme-activated rotaxane propeptides

scientific article

Securing a Supramolecular Architecture by Tying a Stopper Knot

scientific article published on 27 May 2018

Selecting reactions and reactants using a switchable rotaxane organocatalyst with two different active sites

scientific article

Selecting topology and connectivity through metal-directed macrocyclization reactions: a square planar palladium [2]catenate and two noninterlocked isomers.

scientific article

Self-Sorting Assembly of Molecular Trefoil Knots of Single Handedness

scientific article published on 07 August 2019

Self-assembly of a layered two-dimensional molecularly woven fabric

scientific article published on 16 December 2020

Self-organization of nano-lines and dots triggered by a local mechanical stimulus

scientific article

Self-organization of rotaxane thin films into spatially correlated nanostructures: morphological and structural aspects

scientific article published in January 2006

Sequence isomerism in [3]rotaxanes

scientific article published in April 2010

Sequence-Specific β-Peptide Synthesis by a Rotaxane-Based Molecular Machine

scientific article published on 19 July 2017

Sequence-specific peptide synthesis by an artificial small-molecule machine

scientific article

Shaping of a Conformationally Flexible Molecular Structure for Spectroscopy

scientific article published on 01 January 2008

Shuttling through Anion Recognition

article by Claire M. Keaveney & David Leigh published 27 February 2004 in Angewandte Chemie International Edition

Shuttling through reversible covalent chemistry

scientific article published on 23 September 2004

Single-Step Enantioselective Synthesis of Mechanically Planar Chiral [2]Rotaxanes Using a Chiral Leaving Group Strategy

scientific article published on 01 May 2020

Solid-State Fingerprints of Molecular Threading Detected by Inelastic Neutron Scattering

scientific article published on 01 December 2002

Solid-state optical properties of the methyl-exopyridine–anthracene rotaxane

Spontaneous Assembly of Rotaxanes from a Primary Amine, Crown Ether and Electrophile

scientific article published on 03 May 2018

Stereodivergent synthesis with a programmable molecular machine

scientific article published in September 2017

Stereoselective Synthesis of Molecular Square and Granny Knots

scientific article published in 2019

Stereoselective synthesis of a composite knot with nine crossings

scientific article published on 10 September 2018

Stiff, and Sticky in the Right Places: Binding Interactions in Isolated Mechanically Interlocked Molecules Probed by Mid-Infrared Spectroscopy

scientific article published on 01 February 2009

Stiff, and Sticky in the Right Places: The Dramatic Influence of Preorganizing Guest Binding Sites on the Hydrogen Bond-Directed Assembly of Rotaxanes

scientific article published on 01 June 2001

Strategies and tactics for the metal-directed synthesis of rotaxanes, knots, catenanes, and higher order links

scientific article published on 16 September 2011

Strong and Selective Anion Binding within the Central Cavity of Molecular Knots and Links

scientific article published on 13 July 2015

Successive Translocation of the Rings in a [3]Rotaxane

scientific article published on 29 March 2016

Summing Up Ligand Binding Interactions

scientific article published on 01 December 2003

Surface Enhanced Second Harmonic Generation from Macrocycle, Catenane, and Rotaxane Thin Films: Experiments and Theory

scientific article published on 01 April 2006

Surface enhanced SHG from macrocycle, catenane and rotaxane thin films: experiments and theory

Switchable Dual Binding Mode Molecular Shuttle

scientific article published on 01 November 2006

Switching between Anion-Binding Catalysis and Aminocatalysis with a Rotaxane Dual-Function Catalyst.

scientific article

Switching “On” and “Off” the Expression of Chirality in Peptide Rotaxanes

scientific article published on 01 March 2002

Synthesis and solid state structure of a hydrazone-disulfide macrocycle and its dynamic covalent ring-opening under acidic and basic conditions

scientific article published on 20 August 2010

Synthesis, Structure, and Dynamic Properties of Hybrid Organic−Inorganic Rotaxanes

article

Synthetic Molecular Motors and Mechanical Machines

scientific article (publication date: 2007)

Synthetic molecular walkers

scientific article

Template synthesis of molecular knots

scientific article published on 13 August 2012

Tetrameric cyclic double helicates as a scaffold for a molecular Solomon link

scientific article published on 6 May 2013

The Mechanism of Formation of Amide-Based Interlocked Compounds: Prediction of a New Rotaxane-Forming Motif

scientific article published on 01 October 2004

The application of CuAAC 'click' chemistry to catenane and rotaxane synthesis

scientific article

The effect of guest inclusion on the crystal packing of p-tert-butylcalix[4]arenes

scientific article

The effect of mechanical interlocking on crystal packing: predictions and testing

scientific article published in January 2002

The facile conversion of T-2 toxin and neosolaniol into anguidine

The regioselective tert-butyldimenthylsilylation of the 6′-hydroxyl group of lactose derivatives via their dibutylstannylene acetals

article

The self-sorting behavior of circular helicates and molecular knots and links

scientific article published on 4 June 2014

Three state redox-active molecular shuttle that switches in solution and on a surface

scientific article published on 6 February 2008

Time-resolved vibrational spectroscopy of a molecular shuttle

scientific article published on 28 October 2011

Toward Metal Complexes That Can Directionally Walk Along Tracks: Controlled Stepping of a Molecular Biped with a Palladium(II) Foot

scientific article published on 22 January 2014

Transient two-dimensional vibrational spectroscopy of an operating molecular machine.

scientific article published on 20 December 2017

Transmembrane Ion Channels Formed by a Star of David [2]Catenane and a Molecular Pentafoil Knot

scientific article published on 21 October 2020

Triply Threaded [4]Rotaxanes

scientific article published on 13 September 2016

Two Axles Threaded Using a Single Template Site: Active Metal Template Macrobicyclic [3]Rotaxanes

scientific article published on 01 January 2010

Two-Dimensional Vibrational Spectroscopy of Rotaxane-Based Molecular Machines

article

Tying a Molecular Overhand Knot of Single Handedness and Asymmetric Catalysis with the Corresponding Pseudo-D3-Symmetric Trefoil Knot

scientific article published on 26 September 2016

Tying different knots in a molecular strand

scientific article published on 26 August 2020

Unidirectional rotation in a mechanically interlocked molecular rotor

scientific article published in Nature

Unorthodox rate enhancement in the Mannich reaction of para-substituted phenols containing electron-withdrawing groups

Walking molecules

scientific article published on 17 March 2011

Water lubricates hydrogen-bonded molecular machines

scientific article

Weak functional group interactions revealed through metal-free active template rotaxane synthesis

scientific article published on 06 February 2020

White light emission from C60 molecules confined in molecular cage materials

article by Bruce Hamilton et al published July 1993 in Advanced Materials

[2]Rotaxane Formation by Transition State Stabilization

scientific article published on 16 June 2017

[2]Rotaxanes through Palladium Active-Template Oxidative Heck Cross-Couplings

scientific article published on 18 September 2007

“Magic Rod” Rotaxanes:  The Hydrogen Bond-Directed Synthesis of Molecular Shuttles under Thermodynamic Control

scientific article published on 01 May 2003

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