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List of works by Gerald Crabtree

Chemically induced proximity in biology and medicine.

scientific article published in March 2018

Chromatin regulators mediate anthracycline sensitivity in breast cancer

scientific article published on 07 November 2019

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.

scientific article published on 11 December 2017

LSH mediates gene repression through macroH2A deposition

scientific article published on 06 November 2020

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics

scientific article

Our Fragile Intellect

article by Gerald Crabtree

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

scientific article

Rapid and reversible epigenome editing by endogenous chromatin regulators

scientific article published on 15 September 2017

Rapid chromatin repression by Aire provides precise control of immune tolerance

scientific article published on 15 January 2018

Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma

scientific article

Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin

scientific article published on 12 December 2016

TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin

scientific article published on 27 February 2017

mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution

scientific article published on 11 June 2021