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List of works by Wolfgang Schamel

A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation

scientific article

A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum

scientific article

A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes

scientific article

Activation loop phosphorylation regulates B-Raf in vivo and transformation by B-Raf mutants

scientific article

Activation of the TCR complex by peptide-MHC and superantigens

scientific article published on January 2014

Activation of the TCR complex by small chemical compounds

scientific article published on January 2014

Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors

scientific article

Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling

scientific article

Antitumor activities of PSMA×CD3 diabodies by redirected T-cell lysis of prostate cancer cells

scientific article published on January 2013

Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency

scientific article published on 21 December 2011

B cell antigen receptor-induced activation of an IRAK4-dependent signaling pathway revealed by a MALT1-IRAK4 double knockout mouse model ⬇️

scientific article published on March 11, 2011

Biochemical differences in the alphabeta T cell receptor.CD3 surface complex between CD8+ and CD4+ human mature T lymphocytes

scientific article published on April 2004

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for analysis of multiprotein complexes from cellular lysates

scientific article published on 24 February 2011

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes

scientific article published on 25 July 2006

Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering

scientific article published on 22 October 2012

Clustering models

scientific article published on January 2008

Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

scientific article

Correction: Nck Binds to the T Cell Antigen Receptor Using Its SH3.1 and SH2 Domains in a Cooperative Manner, Promoting TCR Functioning

scientific article published in June 2016

Detection of phosphorylated T and B cell antigen receptor species by Phos-tag SDS- and Blue Native-PAGE.

scientific article

Detection of protein complex interactions via a Blue Native-PAGE retardation assay

scientific article

Differences in pairing and cluster formation of T cell receptor alpha- and beta-chains in T cell clones and fusion hybridomas

scientific article published in January 2005

Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies

scientific article published on 8 October 2007

Differential antibody binding to the surface alphabetaTCR.CD3 complex of CD4+ and CD8+ T lymphocytes is conserved in mammals and associated with differential glycosylation

scientific article published on 24 July 2008

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

scientific article

Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells

scientific article published in Scientific Reports

Enhanced B-cell activation mediated by TLR4 and BCR crosstalk

scientific article published in September 2008

Erratum for Maler et al., "Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages".

scientific article published on 26 September 2017

High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry

scientific article published on 05 June 2007

Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system

scientific article published on 28 July 2006

Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes

scientific article published on 8 September 2011

Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol

scientific article published on 23 May 2016

Initiation of TCR signaling: regulation within CD3 dimers

scientific article

Interaction of KLRG1 with E-cadherin: new functional and structural insights

scientific article

Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages

scientific article published on August 2017

Kidins220/ARMS associates with B-Raf and the TCR, promoting sustained Erk signaling in T cells

scientific article

Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation

scientific article

Meeting report: Signal transduction meets systems biology

scientific article published on 30 April 2012

Models of antigen receptor activation in the design of vaccines

scientific article published on January 2009

Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains

scientific article published on 20 December 2014

Nck Binds to the T Cell Antigen Receptor Using Its SH3.1 and SH2 Domains in a Cooperative Manner, Promoting TCR Functioning

scientific article published on 20 November 2015

Nck Recruitment to the TCR Required for ZAP70 Activation during Thymic Development ⬇️

scientific article published on December 24, 2012

Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation

scientific article published on 26 March 2014

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

scientific article

Organization of the resting TCR in nanoscale oligomers

scientific article

Permissive geometry model

scientific article published on January 2008

Pre-clustering of the B cell antigen receptor demonstrated by mathematically extended electron microscopy

scientific article published on 6 December 2013

Pre‐clustered TCR complexes ⬇️

scientific article published on 07 September 2010

Purification of the T cell antigen receptor and analysis by blue-native PAGE.

scientific article

Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-Colour IP-FCM as an Input for Kinetic Modelling of Signalling Networks ⬇️

scientific article published on July 29, 2011

Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

scientific article

Red Light-Regulated Reversible Nuclear Localization of Proteins in Mammalian Cells and Zebrafish

scientific article published on 24 March 2015

Response to Comment on "A Novel Thymoma-Associated Immunodeficiency with Increased Naive T Cells and Reduced CD247 Expression".

scientific article

SYK expression endows human ZAP70-deficient CD8 T cells with residual TCR signaling

scientific article published on 14 July 2015

Segregation models

scientific article published on January 2008

Selected signalling proteins recruited to the T-cell receptor-CD3 complex

scientific article published on 3 August 2017

Stoichiometry and intracellular fate of TRIM-containing TCR complexes

scientific article

Subproteomic analysis of metal-interacting proteins in human B cells

scientific article published on September 2005

Synthetic immune signaling ⬇️

scientific article published on February 10, 2012

T cell expansion is the limiting factor of virus control in mice with attenuated TCR signaling: implications for human immunodeficiency

scientific article published on 11 February 2015

T cell receptor engagement triggers its CD3epsilon and CD3zeta subunits to adopt a compact, locked conformation

scientific article

T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity

scientific article

Target-dependent T-cell activation by coligation with a PSMA x CD3 diabody induces lysis of prostate cancer cells

scientific article

The Allostery Model of TCR Regulation

scientific article published on January 2017

The CD3 conformational change in the γδ T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing

scientific article

The TCR binding site does move

scholarly article

The extracellular part of zeta is buried in the T cell antigen receptor complex

scientific article published on 31 December 2007

The short length of the extracellular domain of zeta is crucial for T cell antigen receptor function

scientific article published on 26 December 2007

The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells

scientific article published on 27 July 2015

Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes

scientific article published in December 2005

Two-dimensional Blue native/SDS gel electrophoresis of multi-protein complexes from whole cellular lysates: a proteomics approach

scientific article

Two-dimensional blue native polyacrylamide gel electrophoresis

scientific article

Visualization of TCR nanoclusters via immunogold labeling, freeze-etching, and surface replication

scientific article published on January 2013

γδ T-cell conference 2012: close encounters for the fifth time

scientific article published in December 2012

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