List of works by Nicholas R. Cozzarelli

11 Escherichia coli DNA gyrase

scientific article published on 01 January 1983

13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation

scientific article

A Sign Inversion Mechanism for Enzymatic Supercoiling of DNA ⬇️

scientific article published on November 30, 1979

A Topological Treatment of Recombination and Topoisomerases ⬇️

scientific article published on 01 January 1984

A genetic selection for supercoiling mutants of Escherichia coli reveals proteins implicated in chromosome structure

scientific article

A minute circular DNA from Escherichia coli 15 ⬇️

scientific article

A topoisomerase from Escherichia coli related to DNA gyrase ⬇️

scientific article published on December 1, 1979

Accumulation of Toxic Concentrations of Methylglyoxal by Wild-Type Escherichia coli K-12 ⬇️

scientific article published on August 1, 1974

Addition of oligonucleotides to the 5′-terminus of DNA by T4 RNA ligase ⬇️

scientific article published on March 1, 1979

Alteration of Escherichia coli topoisomerase IV conformation upon enzyme binding to positively supercoiled DNA.

scientific article

Alteration of Escherichia coli topoisomerase IV to novobiocin resistance

scientific article

An open access option for PNAS.

scientific article

An open letter to Elias Zerhouni

scientific article published on 01 March 2005

Analysis of amplified DNAs from drug-resistant Leishmania by orthogonal-field-alternation gel electrophoresis. The effect of size and topology on mobility

scientific article published in February 1989

Analysis of strand exchange and DNA binding of enhancer-independent Gin recombinase mutants.

scientific article published on March 1993

Analysis of the mechanism of DNA recombination using tangles

scientific article published on August 1995

Analysis of topoisomerase function in bacterial replication fork movement: use of DNA microarrays

scientific article

Bacteriophage T4 RNA ligase. Reaction intermediates and interaction of substrates ⬇️

scientific article published on March 10, 1977

Bacteriophage T4-Directed DNA Synthesis in Toluene-Treated Cells ⬇️

scientific article published on December 1, 1973

Biochemical topology: applications to DNA recombination and replication

scientific article

Biographies of newly elected Academy members

scientific article published on 3 November 2003

Bypass of heterology during strand transfer by Saccharomyces cerevisiae Rad51 protein

scientific article published on December 2001

C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis

scientific article

Catenation and knotting of duplex DNA by type 1 topoisomerases: a mechanistic parallel with type 2 topoisomerases

scientific article

Catenation of DNA rings by topoisomerases. Mechanism of control by spermidine ⬇️

scientific article published on March 10, 1982

Changes in network topology during the replication of kinetoplast DNA

scientific article

Characterization of simian virus 40 T-antigen double hexamers bound to a replication fork. The active form of the helicase

scientific article

Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases

scientific article

Chromosomal Location of the Structural Gene for Glycerol Kinase in Escherichia coli ⬇️

scientific article

Comparison of recombination in vitro and in E. coli cells: measure of the effective concentration of DNA in vivo.

scientific article

Conformational and thermodynamic properties of supercoiled DNA

scientific article published on 01 October 1992

Conformational and thermodynamic properties of supercoiled DNA.

scientific article published on January 1994

Contrasting enzymatic activities of topoisomerase IV and DNA gyrase from Escherichia coli

scientific article published in December 1996

Contributions of supercoiling to Tn3 resolvase and phage Mu Gin site-specific recombination

scientific article published in February 1996

DNA Gyrase and the Supercoiling of DNA ⬇️

scientific article published on February 29, 1980

DNA gyrase subunit stoichiometry and the covalent attachment of subunit A to DNA during DNA cleavage ⬇️

scientific article published on September 11, 1980

DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli

scientific article

DNA overwinds when stretched

scientific article

Description of the topological entanglement of DNA catenanes and knots by a powerful method involving strand passage and recombination

scientific article

Determination of the absolute handedness of knots and catenanes of DNA

scientific article published in Nature

Directed assembly of DNA molecules via simultaneous ligation and digestion

scientific article

Disentangling DNA during replication: a tale of two strands

scientific article

Duplex DNA knots produced by Escherichia coli topoisomerase I. Structure and requirements for formation.

scientific article

Editor'S note.

scientific article

Editorial expression of concern

scientific article published on September 2003

Energy coupling in DNA gyrase and the mechanism of action of novobiocin ⬇️

scientific article published on October 1, 1978

Enzymatic synthesis of deoxyribonucleic acid. XXXII. Replication of duplex deoxyribonucleic acid by polymerase at a single strand break

scientific article published on 01 January 1970

Enzymic synthesis of DNA. 33. Hydrolysis of a 5'-triphosphate-terminated polynucleotide in the active center of DNA polymerase

scientific article published on 01 November 1969

Equilibrium distributions of topological states in circular DNA: interplay of supercoiling and knotting

scientific article published on November 1999

Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth ⬇️

scientific article published on November 1, 1979

Escherichia coli type-1 topoisomerases: identification, mechanism, and role in recombination

scientific article published on 01 January 1983

Further genetic and enzymological characterization of the three Bacillus subtilis deoxyribonucleic acid polymerases

scientific article published on 01 November 1973

Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli

scientific article

Geometric arrangements of Tn3 resolvase sites

scientific article

Giant proteins that move DNA: bullies of the genomic playground.

scientific article published on August 2006

Gin-mediated DNA inversion: product structure and the mechanism of strand exchange

scientific article published on February 1988

Gin-mediated recombination of catenated and knotted DNA substrates: implications for the mechanism of interaction between cis-acting sites

scientific article published in July 1989

Growth Stasis by Accumulated l -α-Glycerophosphate in Escherichia coli ⬇️

scientific article

Hda inactivation of DnaA is the predominant mechanism preventing hyperinitiation of Escherichia coli DNA replication

scientific article

Hyperinitiation of DNA replication in Escherichia coli leads to replication fork collapse and inviability

scientific article published on January 2004

Identification of oligonucleotide sequences that direct the movement of the Escherichia coli FtsK translocase

scientific article

Identification of the FtsK sequence-recognition domain

scientific article published on 15 October 2006

Independence of replisomes in Escherichia coli chromosomal replication

scientific article

Inhibition of a DNA Polymerase from Bacillus subtilis by Hydroxyphenylazopyrimidines ⬇️

scientific article published on January 1, 1973

Interaction between DNA gyrase and its cleavage site on DNA ⬇️

scientific article published on March 10, 1980

Introduction to "From the Academy".

scientific article

Isolation and characterization of the Tn3 resolvase synaptic intermediate

scientific article published on June 1988

Knot what we thought before: the twisted story of replication

scientific article

Liberalization of PNAS copyright policy: noncommercial use freely allowed

scholarly article

Linear ordering and dynamic segregation of the bacterial chromosome

scholarly article

Lower open access fees and institutional partnerships

scientific article

Making back issues of PNAS online free

scientific article

Making research accessible: National Institutes of Health (NIH) public access and PNAS open access policies

scholarly article

Mechanism of Tn3 resolvase recombination in vivo ⬇️

scientific article published on February 5, 1991

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme ⬇️

scientific article published on November 1, 1977

Mechanism of inhibition of Bacillus subtilis DNA polymerase 3 by the arylhydrazinopyrimidine antimicrobial agents

scientific article published on August 1974

Mechanism of strand passage by Escherichia coli topoisomerase I. The role of the required nick in catenation and knotting of duplex DNA.

scientific article

Mechanism of topology simplification by type II DNA topoisomerases

scholarly article

Mechanisms of separation of the complementary strands of DNA during replication

scientific article

Mechanochemical analysis of DNA gyrase using rotor bead tracking

scientific article

Monte Carlo analysis of the conformation of DNA catenanes.

scientific article published in August 1993

Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque

scientific article published on 4 March 2007

National Academy of Sciences endorses National Institutes of Health plan for enhanced access to research information

scholarly article

PNAS Early Edition

scientific article

PNAS Profiles: How do Academy members get started in science?

scientific article

PNAS at volume 100.

scholarly article

PNAS gives free online access to developing countries

scientific article

PNAS goes weekly in the new year

scholarly article

PNAS policy on publication of sensitive material in the life sciences

scholarly article

PNAS publishes daily online

scientific article

Packing defects as selectivity switches for drug-based protein inhibitors

scholarly article

Polynucleotide cellulose as a substrate for a polynucleotide ligase induced by phage T4 ⬇️

scientific article published on 01 August 1967

Positive torsional strain causes the formation of a four-way junction at replication forks

scientific article published on 30 October 2000

Power to the people: PubMed Central

scientific article

Prediction of Saccharomyces cerevisiae replication origins

scientific article

Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements.

scientific article

Probability of DNA knotting and the effective diameter of the DNA double helix

scientific article

Processive recombination by the phage Mu Gin system: implications for the mechanisms of DNA strand exchange, DNA site alignment, and enhancer action

scientific article published on July 1990

Processive recombination by wild-type gin and an enhancer-independent mutant. Insight into the mechanisms of recombination selectivity and strand exchange

scientific article published in October 1994

Purification and characterization of DNA polymerase III from Bacillus subtilis.

scientific article published in March 1976

Purification of the Gin recombination protein of Escherichia coli phage Mu and its host factor.

scientific article

Purification of the Tn3 transposase and analysis of its binding to DNA ⬇️

scientific article published on May 25, 1981

Quantitative Analysis of the Contributions of Enzyme and DNA to the Structure of Integrative Recombinants ⬇️

scientific article published on 01 January 1984

Recombination of knotted substrates by Tn3 resolvase

scientific article

Recombination site selection by Tn3 resolvase: topological tests of a tracking mechanism

scientific article published in January 1985

Redesign of PNAS: New Covers for the Journal

scientific article published in January 1999

Redesign of PNAS: getting ready for the millennium

scientific article published on October 1999

Replication of viral DNA in SPO1-infected Bacillus subtilis. I. Replicative intermediates

scientific article

Responsible authorship of papers in PNAS

scholarly article

Results of a PNAS author survey on an open access option for publication

scholarly article

Retracted: The bacterial condensin MukBEF compacts DNA into a repetitive, stable structure

retracted paper

Retraction

scientific article published on 01 March 2005

Revisiting the independence of the publicly and privately funded drafts of the human genome

scholarly article

Roles of topoisomerase IV and DNA gyrase in DNA unlinking during replication in Escherichia coli ⬇️

scientific article published on November 15, 1995

Roles of topoisomerases in maintaining steady-state DNA supercoiling in Escherichia coli

scientific article published on 01 March 2000

SV40 large T antigen hexamer structure: domain organization and DNA-induced conformational changes

scientific article

Second Pyridine Nucleotide-Independent l -α-Glycerophosphate Dehydrogenase in Escherichia coli K-12 ⬇️

scientific article published on November 1969

Sequence-directed DNA export guides chromosome translocation during sporulation in Bacillus subtilis.

scientific article

Sequence-directed DNA translocation by purified FtsK.

scientific article

Simplification of DNA Topology Below Equilibrium Values by Type II Topoisomerases ⬇️

scientific article published on August 1, 1997

Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae

scientific article

Statement on scientific publication and security.

scientific article

Statement on the consideration of biodefence and biosecurity

scientific article published in Nature

Structural and functional properties of Escherichia coli DNA polymerase

scientific article published on 01 January 1968

Structural transitions and elasticity from torque measurements on DNA.

scientific article published on July 2003

Structure and Activities of Escherichia coli DNA Gyrase ⬇️

scientific article published on January 1, 1979

Structure of plectonemically supercoiled DNA.

scientific article published in June 1990

Structure of reaction intermediates formed during Saccharomyces cerevisiae Rad51-catalyzed strand transfer.

scientific article published on 29 July 2002

Supplementary Material Can Now Appear Online

scientific article published in October 1998

The Saccharomyces cerevisiae Smc2/4 condensin compacts DNA into (+) chiral structures without net supercoiling

scientific article

The Sep1 strand exchange protein from Saccharomyces cerevisiae promotes a paranemic joint between homologous DNA molecules.

scientific article

The absence of supercoiling in kinetoplast DNA minicircles.

scientific article published on February 1993

The binding of gyrase to DNA: analysis by retention by nitrocellulose filters

scientific article published on November 1982

The effect of ionic conditions on DNA helical repeat, effective diameter and free energy of supercoiling

scientific article published on April 1997

The effect of ionic conditions on the conformations of supercoiled DNA. I. Sedimentation analysis

scientific article

The effect of ionic conditions on the conformations of supercoiled DNA. II. Equilibrium catenation

scientific article published in March 1997

The helical repeat of double-stranded DNA varies as a function of catenation and supercoiling

scientific article published in August 1988

The helical repeat of underwound DNA in solution ⬇️

scientific article published on July 25, 1988

The intrinsic ATPase of DNA gyrase ⬇️

scientific article published on July 10, 1980

The mechanism of inhibition of topoisomerase IV by quinolone antibacterials

scientific article published in October 1998

The mechanism of type IA topoisomerases

scientific article

The stereostructure of knots and catenanes produced by phage lambda integrative recombination: implications for mechanism and DNA structure

scientific article published in August 1985

The structure and function of DNA supercoiling and catenanes

scientific article

The topological mechanism of phage lambda integrase

scientific article published on June 1999

The topology of the kinetoplast DNA network

scientific article published in January 1995

The two functional domains of gamma delta resolvase act on the same recombination site: implications for the mechanism of strand exchange

scientific article

Topoisomerase IV is a target of quinolones in Escherichia coli

scientific article

Topoisomerase IV, not gyrase, decatenates products of site-specific recombination in Escherichia coli

scientific article

Topoisomerase action on short DNA duplexes reveals requirements for gate and transfer DNA segments

scientific article

Topological challenges to DNA replication: conformations at the fork

scientific article

Topological domain structure of the Escherichia coli chromosome

scientific article published on July 2004

UPSIDE: Uniform principle for sharing integral data and materials expeditiously

scholarly article

Uncensored exchange of scientific results

scholarly article

Unfettered access to published results

scientific article published on 10 July 2001

Webcasting is not publication

scientific article published in July 2003

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