List of works - Valery V. Fokin

"On water": unique reactivity of organic compounds in aqueous suspension

scientific article

A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a Desorption/Ionization on Silicon (DIOS) platform

scientific article published in July 2004

A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry

scientific article published in August 2003

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

scientific article (publication date: 15 July 2002)

A very large diversity space of synthetically accessible compounds for use with drug design programs

scientific article published in January 2005

Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection

scientific article

Arylation of rhodium(II) azavinyl carbenes with boronic acids

scientific article published on 28 August 2012

Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition

scientific article published in March 2003

Catalytic Asymmetric C–H Insertions of Rhodium(II) Azavinyl Carbenes ⬇️

scientific article published on June 20, 2011

Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes

scientific article

Catalytic asymmetric transannulation of NH-1,2,3-triazoles with olefins

scientific article

Centrally acting oximes in reactivation of tabun-phosphoramidated AChE.

scientific article

Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia

scientific article

Click and Pick: Identification of Sialoside Analogues for Siglec‐Based Cell Targeting ⬇️

scientific article published on October 4, 2012

Click imaging of biochemical processes in living systems.

scientific article published in December 2007

Copper(I)-catalyzed cycloaddition of bismuth(III) acetylides with organic azides: synthesis of stable triazole anion equivalents

scientific article

Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes

scientific article

Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates

scientific article

Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides

scientific article

Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching

scientific article

Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas

scientific article

Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

scholarly article by Peng Wu et al published 26 July 2004 in Angewandte Chemie International Edition

Efficient synthesis of 1-sulfonyl-1,2,3-triazoles

scientific article

Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity

scientific article published on 07 October 2013

From BACE1 inhibitor to multifunctionality of tryptoline and tryptamine triazole derivatives for Alzheimer's disease

scientific article published on 10 July 2012

Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template

scientific article

Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach ⬇️

scientific article published on January 2009

Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification

scientific article

Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries

scientific article published on 22 June 2009

Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase

scientific article published on 20 April 2010

Iterative in situ click chemistry creates antibody-like protein-capture agents

scientific article published on January 2009

Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report

scientific article

Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates ⬇️

scientific article published on September 4, 2012

Mechanistic studies on the Cu-catalyzed three-component reactions of sulfonyl azides, 1-alkynes and amines, alcohols, or water: dichotomy via a common pathway

scientific article published on 17 June 2008

Multivalent, bifunctional dendrimers prepared by click chemistry

scientific article published on 4 November 2005

NH-1,2,3-Triazole-based Inhibitors of the VIM-2 Metallo-β-Lactamase: Synthesis and Structure-Activity Studies

scientific article published on July 2010

Neuritogenic activity of bi-functional bis-tryptoline triazole

scientific article published on 23 December 2016

New Structural Scaffolds for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases ⬇️

scientific article published on April 4, 2011

Novel VEGFR-2 kinase inhibitors identified by the back-to-front approach

scientific article

On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7.

scientific article

One-pot copper(I)-catalyzed synthesis of 3,5-disubstituted isoxazoles

scientific article published in September 2005

Organic synthesis "on water".

scientific article published on February 2009

Oxime-assisted Acetylcholinesterase Catalytic Scavengers of Organophosphates That Resist Aging ⬇️

scientific article published on July 5, 2011

Polytriazoles as copper(I)-stabilizing ligands in catalysis

scientific article

Preparation of 1,5-Disubstituted 1,2,3-Triazoles via Ruthenium-catalyzed Azide Alkyne Cycloaddition

scientific article

Quantitative Structure–Price Relationship (QS$R) Modeling and the Development of Economically Feasible Drug Discovery Projects

scientific article published on 28 February 2019

REGIOSELECTIVE SYNTHESIS OF EITHER 1H- OR 2H-1,2,3- TRIAZOLES VIA MICHAEL ADDITION TO α,ß-UNSATURATED KETONES.

scientific article

Rapid Diversity‐Oriented Synthesis in Microtiter Plates for In Situ Screening of HIV Protease Inhibitors ⬇️

scientific article published on November 7, 2003

Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization

scientific article

Reactivity of N-(1,2,4-triazolyl)-substituted 1,2,3-triazoles

scientific article published on 18 August 2011

Refinement of Structural Leads for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases ⬇️

scientific article published on February 16, 2012

Regioselective Synthesis of Fluorosulfonyl 1,2,3-Triazoles from Bromovinylsulfonyl Fluoride

scientific article published on 15 June 2018

Rhodium(II)-Catalyzed Asymmetric Sulfur(VI) Reduction of Diazo Sulfonylamidines ⬇️

scientific article published on January 27, 2012

Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles

scientific article

Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles

scientific article published on 15 October 2008

Ring expansion and rearrangements of rhodium(II) azavinyl carbenes

scientific article published on 19 November 2012

Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism

scientific article

Ruthenium-catalyzed cycloaddition of alkynes and organic azides

scientific article

Ruthenium-catalyzed cycloadditions of 1-haloalkynes with nitrile oxides and organic azides: synthesis of 4-haloisoxazoles and 5-halotriazoles

scientific article published on 24 July 2014

Selectivity optimization of substituted 1,2,3-triazoles as α7 nicotinic acetylcholine receptor agonists

scientific article published in May 2015

Stereoselective 1,3-insertions of rhodium(II) azavinyl carbenes

scientific article published on 17 December 2013

SuFEx-based synthesis of polysulfates

scientific article published on 5 August 2014

Sulfonyl‐1,2,3‐Triazoles: Convenient Synthones for Heterocyclic Compounds ⬇️

scientific article published on December 17, 2012

Sulfuryl Fluoride Mediated Conversion of Aldehydes to Nitriles

scientific article published on 15 January 2019

Synthesis and Reactivity of Sulfamoyl Azides and 1-Sulfamoyl-1,2,3-triazoles ⬇️

scientific article published on August 3, 2011

Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia

scientific article published on July 2009

Synthesis and reactivity of rhodium(II) N-triflyl azavinyl carbenes

scientific article

Synthesis of 7-aza-5-deazapurine analogues via copper(I)-catalyzed hydroamination of alkynes and 1-iodoalkynes

scientific article

Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates

scientific article

The allylic azide rearrangement: achieving selectivity

scientific article published in October 2005

Transannulation of 1-Sulfonyl-1,2,3-triazoles with Heterocumulenes ⬇️

scientific article published on March 15, 2013

Transition-metal-free catalytic synthesis of 1,5-diaryl-1,2,3-triazoles

scientific article

Triazolyl tryptoline derivatives as β-secretase inhibitors

scientific article published on 22 September 2010

Ultrasound-promoted copper-catalyzed azide-alkyne cycloaddition

scientific article

List of works by Valery V. Fokin

"On water": unique reactivity of organic compounds in aqueous suspension

A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a Desorption/Ionization on Silicon (DIOS) platform

A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

A very large diversity space of synthetically accessible compounds for use with drug design programs

Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection

Arylation of rhodium(II) azavinyl carbenes with boronic acids

Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition

Catalytic Asymmetric C–H Insertions of Rhodium(II) Azavinyl Carbenes ⬇️

Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes

Catalytic asymmetric transannulation of NH-1,2,3-triazoles with olefins

Centrally acting oximes in reactivation of tabun-phosphoramidated AChE.

Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia

Click and Pick: Identification of Sialoside Analogues for Siglec‐Based Cell Targeting ⬇️

Click imaging of biochemical processes in living systems.

Copper(I)-catalyzed cycloaddition of bismuth(III) acetylides with organic azides: synthesis of stable triazole anion equivalents

Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes

Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates

Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides

Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching

Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas

Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

Efficient synthesis of 1-sulfonyl-1,2,3-triazoles

Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity

From BACE1 inhibitor to multifunctionality of tryptoline and tryptamine triazole derivatives for Alzheimer's disease

Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template

Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach ⬇️

Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification

Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries

Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase

Iterative in situ click chemistry creates antibody-like protein-capture agents

Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report

Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates ⬇️

Mechanistic studies on the Cu-catalyzed three-component reactions of sulfonyl azides, 1-alkynes and amines, alcohols, or water: dichotomy via a common pathway

Multivalent, bifunctional dendrimers prepared by click chemistry

NH-1,2,3-Triazole-based Inhibitors of the VIM-2 Metallo-β-Lactamase: Synthesis and Structure-Activity Studies

Neuritogenic activity of bi-functional bis-tryptoline triazole

New Structural Scaffolds for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases ⬇️

Novel VEGFR-2 kinase inhibitors identified by the back-to-front approach

On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7.

One-pot copper(I)-catalyzed synthesis of 3,5-disubstituted isoxazoles

Organic synthesis "on water".

Oxime-assisted Acetylcholinesterase Catalytic Scavengers of Organophosphates That Resist Aging ⬇️

Polytriazoles as copper(I)-stabilizing ligands in catalysis

Preparation of 1,5-Disubstituted 1,2,3-Triazoles via Ruthenium-catalyzed Azide Alkyne Cycloaddition

Quantitative Structure–Price Relationship (QS$R) Modeling and the Development of Economically Feasible Drug Discovery Projects

REGIOSELECTIVE SYNTHESIS OF EITHER 1H- OR 2H-1,2,3- TRIAZOLES VIA MICHAEL ADDITION TO α,ß-UNSATURATED KETONES.

Rapid Diversity‐Oriented Synthesis in Microtiter Plates for In Situ Screening of HIV Protease Inhibitors ⬇️

Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization

Reactivity of N-(1,2,4-triazolyl)-substituted 1,2,3-triazoles

Refinement of Structural Leads for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases ⬇️

Regioselective Synthesis of Fluorosulfonyl 1,2,3-Triazoles from Bromovinylsulfonyl Fluoride

Rhodium(II)-Catalyzed Asymmetric Sulfur(VI) Reduction of Diazo Sulfonylamidines ⬇️

Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles

Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles

Ring expansion and rearrangements of rhodium(II) azavinyl carbenes

Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism

Ruthenium-catalyzed cycloaddition of alkynes and organic azides

Ruthenium-catalyzed cycloadditions of 1-haloalkynes with nitrile oxides and organic azides: synthesis of 4-haloisoxazoles and 5-halotriazoles

Selectivity optimization of substituted 1,2,3-triazoles as α7 nicotinic acetylcholine receptor agonists

Stereoselective 1,3-insertions of rhodium(II) azavinyl carbenes

SuFEx-based synthesis of polysulfates

Sulfonyl‐1,2,3‐Triazoles: Convenient Synthones for Heterocyclic Compounds ⬇️

Sulfuryl Fluoride Mediated Conversion of Aldehydes to Nitriles

Synthesis and Reactivity of Sulfamoyl Azides and 1-Sulfamoyl-1,2,3-triazoles ⬇️

Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia

Synthesis and reactivity of rhodium(II) N-triflyl azavinyl carbenes

Synthesis of 7-aza-5-deazapurine analogues via copper(I)-catalyzed hydroamination of alkynes and 1-iodoalkynes

Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates

The allylic azide rearrangement: achieving selectivity

Transannulation of 1-Sulfonyl-1,2,3-triazoles with Heterocumulenes ⬇️

Transition-metal-free catalytic synthesis of 1,5-diaryl-1,2,3-triazoles

Triazolyl tryptoline derivatives as β-secretase inhibitors

Ultrasound-promoted copper-catalyzed azide-alkyne cycloaddition