List of works - Margaret Buckingham

A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis

scientific article

A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

scientific article

An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart

scientific article published on 02 October 2008

An enhancer directs differential expression of the linked Mrf4 and Myf5 myogenic regulatory genes in the mouse.

scientific article published in May 2004

An interview with Margaret Buckingham: President of the French Society of Developmental Biology. [Interviewed by Eva Amsen].

scientific article published in February 2011

Analysis of Mlc-lacZ Met mutants highlights the essential function of Met for migratory precursors of hypaxial muscles and reveals a role for Met in the development of hyoid arch-derived facial muscles

scientific journal article

Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus.

scientific article published in August 2003

Beta catenin-independent activation of MyoD in presomitic mesoderm requires PKC and depends on Pax3 transcriptional activity

scientific article published on 09 January 2007

Building the mammalian heart from two sources of myocardial cells

scientific article (publication date: November 2005)

Characterization of Pax3-expressing cells from adult blood vessels

scientific article published on 8 December 2011

Conotruncal defects associated with anomalous pulmonary venous connections.

scientific article published on 25 February 2009

Conserved functions of Pax3/7 during evolution

Developmental mechanisms, patterning and evolution.

scientific article published in July 2010

Direct isolation of satellite cells for skeletal muscle regeneration

scientific article published in September 2005

Distinct and dynamic myogenic populations in the vertebrate embryo.

scientific article published on 15 September 2009

Divergent functions of murine Pax3 and Pax7 in limb muscle development

scientific journal article

Fine-tuning the onset of myogenesis by homeobox proteins that interact with the Myf5 limb enhancer

scientific article published on 4 November 2015

Gene regulatory networks and cell lineages that underlie the formation of skeletal muscle

scientific article

Gene regulatory networks and transcriptional mechanisms that control myogenesis

scientific article

How the community effect orchestrates muscle differentiation

scientific article

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo

scientific journal article

Interactions with John Gurdon--muscle as a mesodermal read-out and the community effect

scientific article published in July 2014

Lack of In Vivo Functional Compensation Between Pax Family Groups II and III in Rodents

scientific article published on 21 April 2011

Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart

scientific article published on 03 May 2006

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing

scientific article published in August 2012

Lying low but ready for action: the quiescent muscle satellite cell

scientific article

Margaret Buckingham: studying the choreography of cardiogenesis. Interviewed by Ruth Williams

scientific article published in March 2012

Megarole for microRNA in muscle disease ⬇️

scientific article published on November 3, 2010

Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice

scientific article

Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules

scientific article published in July 2012

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.

scholarly article

Myocardial cell lineages in the mammalian embryo: The second heart field

Myogenic progenitor cells and skeletal myogenesis in vertebrates

scientific article published on 22 August 2006

Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survival and myogenic potential

scientific article published on 13 October 2006

Non conservation of function for the evolutionarily conserved prdm1 protein in the control of the slow twitch myogenic program in the mouse embryo.

scientific article published on 20 April 2012

Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb

scientific article

PAX3 and PAX7 as upstream regulators of myogenesis

scientific article published on 27 September 2015

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.

scientific article

Pax3( GFP ) , a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin

scientific article published on 12 July 2012

Pitx2 and Pitx3 transcription factors: two key regulators of the redox state in adult skeletal muscle stem cells and muscle regeneration

scientific article published in October 2014

Progressive developmental restriction, acquisition of left-right identity and cell growth behavior during lobe formation in mouse liver development

scientific article published on 18 February 2016

Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis

scientific article published in May 2014

Resolving cell lineage contributions to the ventricular conduction system with a Cx40-GFP allele: a dual contribution of the first and second heart fields

scientific article

Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis

scientific article

Six proteins regulate the activation of Myf5 expression in embryonic mouse limbs

scientific journal article

Skeletal Muscle Differentiation of Embryonic Mesoangioblasts Requires Pax3 Activity

scientific article published on 01 January 2009

Skeletal muscle progenitor cells and the role of Pax genes

scientific article published on 13 June 2007

Skeletal muscle stem cells

scientific article published on 30 July 2008

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

scientific journal article

The early epaxial enhancer is essential for the initial expression of the skeletal muscle determination gene Myf5 but not for subsequent, multiple phases of somitic myogenesis.

scientific article

The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo

scientific journal article

The formation of skeletal muscle: from somite to limb

scientific article

The formation of the embryonic mouse heart: heart fields and myocardial cell lineages.

scientific article published in February 2010

The regulatory mechanisms that underlie inappropriate transcription of the myogenic determination gene Myf5 in the central nervous system.

scientific article published on 7 December 2008

The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions

scientific article published on January 2007

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

scientific article

Tissue Differentiation: A Personal Account of Research on Myogenesis and Cardiogenesis

scientific article

Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo

scientific article

What does the concept of the stem cell niche really mean today?

scientific article

[The mouse as a model for heart morphogenesis in mammals: the origin of myocytes and studies with cardiac explants]

scientific article published on 01 January 2003

[The mouse as a model of heart morphogenesis in mammals: origin and lineage of myocytes].

scientific article published in January 2003

microRNAs gain magnitude in muscle.

scientific article published in November 2009

List of works by Margaret Buckingham

A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis

A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart

An enhancer directs differential expression of the linked Mrf4 and Myf5 myogenic regulatory genes in the mouse.

An interview with Margaret Buckingham: President of the French Society of Developmental Biology. [Interviewed by Eva Amsen].

Analysis of Mlc-lacZ Met mutants highlights the essential function of Met for migratory precursors of hypaxial muscles and reveals a role for Met in the development of hyoid arch-derived facial muscles

Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus.

Beta catenin-independent activation of MyoD in presomitic mesoderm requires PKC and depends on Pax3 transcriptional activity

Building the mammalian heart from two sources of myocardial cells

Characterization of Pax3-expressing cells from adult blood vessels

Conotruncal defects associated with anomalous pulmonary venous connections.

Conserved functions of Pax3/7 during evolution

Developmental mechanisms, patterning and evolution.

Direct isolation of satellite cells for skeletal muscle regeneration

Distinct and dynamic myogenic populations in the vertebrate embryo.

Divergent functions of murine Pax3 and Pax7 in limb muscle development

Fine-tuning the onset of myogenesis by homeobox proteins that interact with the Myf5 limb enhancer

Gene regulatory networks and cell lineages that underlie the formation of skeletal muscle

Gene regulatory networks and transcriptional mechanisms that control myogenesis

How the community effect orchestrates muscle differentiation

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo

Interactions with John Gurdon--muscle as a mesodermal read-out and the community effect

Lack of In Vivo Functional Compensation Between Pax Family Groups II and III in Rodents

Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing

Lying low but ready for action: the quiescent muscle satellite cell

Margaret Buckingham: studying the choreography of cardiogenesis. Interviewed by Ruth Williams

Megarole for microRNA in muscle disease ⬇️

Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice

Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.

Myocardial cell lineages in the mammalian embryo: The second heart field

Myogenic progenitor cells and skeletal myogenesis in vertebrates

Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survival and myogenic potential

Non conservation of function for the evolutionarily conserved prdm1 protein in the control of the slow twitch myogenic program in the mouse embryo.

Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb

PAX3 and PAX7 as upstream regulators of myogenesis

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.

Pax3( GFP ) , a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin

Pitx2 and Pitx3 transcription factors: two key regulators of the redox state in adult skeletal muscle stem cells and muscle regeneration

Progressive developmental restriction, acquisition of left-right identity and cell growth behavior during lobe formation in mouse liver development

Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis

Resolving cell lineage contributions to the ventricular conduction system with a Cx40-GFP allele: a dual contribution of the first and second heart fields

Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis

Six proteins regulate the activation of Myf5 expression in embryonic mouse limbs

Skeletal Muscle Differentiation of Embryonic Mesoangioblasts Requires Pax3 Activity

Skeletal muscle progenitor cells and the role of Pax genes

Skeletal muscle stem cells

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

The early epaxial enhancer is essential for the initial expression of the skeletal muscle determination gene Myf5 but not for subsequent, multiple phases of somitic myogenesis.

The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo

The formation of skeletal muscle: from somite to limb

The formation of the embryonic mouse heart: heart fields and myocardial cell lineages.

The regulatory mechanisms that underlie inappropriate transcription of the myogenic determination gene Myf5 in the central nervous system.

The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

Tissue Differentiation: A Personal Account of Research on Myogenesis and Cardiogenesis

Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo

What does the concept of the stem cell niche really mean today?

[The mouse as a model for heart morphogenesis in mammals: the origin of myocytes and studies with cardiac explants]

[The mouse as a model of heart morphogenesis in mammals: origin and lineage of myocytes].

microRNAs gain magnitude in muscle.