List of works - Oliver Kayser

1H NMR based metabolite profiling with special focus on tropane alkaloids in Duboisia species

A new approach for targeting to Cryptosporidium parvum using mucoadhesive nanosuspensions: research and applications

scientific article published on 01 February 2001

Amphotericin B.

scientific article

An endophytic fungus Phyllosticta capitalensis harboring uncultivable endosymbiotic bacterium Herbaspirillum sp. produces lactam-fused 4-pyrones

Anti-cancer and antibacterial trioxacarcins with high anti-malaria activity from a marine Streptomycete and their absolute stereochemistry

scientific article published in December 2004

Antibacterial Activity of Rhodomyrtus tomentosa (Aiton) Hassk. Leaf Extract against Clinical Isolates of Streptococcus pyogenes

scientific article

Antibacterial Azaphilones from an Endophytic Fungus, Colletotrichum sp. BS4. ⬇️

scientific article published on 24 February 2016

Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme

scientific article

Antibacterial activity of simple coumarins: structural requirements for biological activity.

scientific article published in March 1999

Antileishmanial activities of aphidicolin and its semisynthetic derivatives

scientific article published on January 2001

Antileishmanial activity of hydrolyzable tannins and their modulatory effects on nitric oxide and tumour necrosis factor-alpha release in macrophages in vitro.

scientific article

Antileishmanial activity of piceatannol isolated from Euphorbia lagascae seeds.

scientific article published in April 2008

Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae).

scientific article published in April 2003

Antileishmanial structure-activity relationships of synthetic phospholipids: in vitro and in vivo activities of selected derivatives

scientific article

Antimicrobial, antitumor and antileishmania screening of medicinal plants from Guinea-Bissau

scientific article published on 01 July 1999

Antiparasitic activity of marine pyridoacridone alkaloids related to the ascididemins

scientific article published on 01 June 2003

Aurones interfere with Leishmania major mitochondrial fumarate reductase

scientific article published in July 2002

Biocontrol potential of endophytes harbored in Radula marginata (liverwort) from the New Zealand ecosystem

scientific article published on 7 August 2014

Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4.

scientific article published on 5 June 2006

Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast

scientific article published on 12 October 2020

Characterization of nebulized buparvaquone nanosuspensions--effect of nebulization technology

scientific article

Combinatorial biosynthesis of medicinal plant secondary metabolites

scientific article published on 22 August 2006

Conformational sampling for large-scale virtual screening: accuracy versus ensemble size.

scientific article

Cytotoxicity studies of Dynasan 114 solid lipid nanoparticles (SLN) on RAW 264.7 macrophages-impact of phagocytosis on viability and cytokine production

scientific article published on July 2004

Delivery of amphotericin B nanosuspensions to the brain and determination of activity against Balamuthia mandrillaris amebas

scientific article

Delivery strategies for antiparasitics.

scientific article

Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using 1H NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis

scientific article

Elucidation of structure-function relationship of THCA and CBDA synthase from Cannabis sativaL

scientific article published on 24 July 2018

Endophytes are hidden producers of maytansine in Putterlickia roots

scientific article

Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid

scientific article published on 17 July 2015

Enhancement of antimicrobial activity of tannins and related compounds by immune modulatory effects.

scientific article

Evaluation of in vitro activity of aurones and related compounds against Cryptosporidium parvum

scientific article published in November 2001

Evaluation of in vitro and in vivo activity of benzindazole-4,9-quinones against Cryptosporidium parvum

scientific article published on December 2002

Evaluation of the antimicrobial potency of tannins and related compounds using the microdilution broth method

scientific article published on 01 June 1999

Formulation of amphotericin B as nanosuspension for oral administration

scientific article

Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis

scientific article published on 26 April 2007

Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania major-infected macrophage-like RAW 264.7 cells treated with gallic acid

scientific article published in October 2004

HPLC detection of miltefosine using an evaporative light scattering detector.

scientific article published in May 2006

HPLC-photodiode array detection analysis of curcuminoids in Curcuma species indigenous to Indonesia

scientific article

Heavy metal contamination of nanosuspensions produced by high-pressure homogenisation

scientific article published on 01 March 2000

Heterologous expression of pentalenene synthase (PSS) from Streptomyces UC5319 in Xanthophyllomyces dendrorhous.

scientific article published on 4 July 2012

Identification of lignans and related compounds in Anthriscus sylvestris by LC-ESI-MS/MS and LC-SPE-NMR.

scientific article

Immunomodulatory principles of Pelargonium sidoides

scientific article

In Vivo Validation of In Silico Predicted Metabolic Engineering Strategies in Yeast: Disruption of α-Ketoglutarate Dehydrogenase and Expression of ATP-Citrate Lyase for Terpenoid Production

scientific article published on 23 December 2015

In silico profiling of Escherichia coli and Saccharomyces cerevisiae as terpenoid factories.

scientific article published on 23 September 2013

In vitro activity of aurones against Plasmodium falciparum strains K1 and NF54.

scientific article published in November 2001

In vitro leishmanicidal activity of aurones

scientific article published on May 1999

In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones

scientific article published on 01 September 2000

In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones.

scientific article published in December 2000

In vitro leishmanicidal activity of naturally occurring chalcones

scientific article

In vitro regeneration of wild chervil (Anthriscus sylvestris L.).

scientific article published on 25 October 2011

Inhibition of mutagenesis of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) by coumarins and furanocoumarins, chromanones and furanochromanones.

scientific article published in November 1995

Leishmanicidal activity of aurones

scientific article published on 01 December 1998

Leishmanicidal and antiplasmodial activity of constituents of Smirnowia iranica

scientific article

Lignans from cell suspension cultures of Phyllanthus niruri, an Indonesian medicinal plant.

scientific article published in January 2006

Lipase degradation of Dynasan 114 and 116 solid lipid nanoparticles (SLN)--effect of surfactants, storage time and crystallinity

scientific article published in April 2002

Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption

scientific article published in May 2004

Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate

scientific article published in August 2002

Metabolic stereoselectivity of cytochrome P450 3A4 towards deoxypodophyllotoxin: In silico predictions and experimental validation

scientific article published on 19 September 2007

Molecular cloning and characterization of a broad substrate terpenoid oxidoreductase from Artemisia annua

scientific article

Monitoring Metabolite Profiles of Cannabis sativa L. Trichomes during Flowering Period Using 1H NMR-Based Metabolomics and Real-Time PCR.

scientific article

Nanosuspensions as a new approach for the formulation for the poorly soluble drug tarazepide

scientific article published on 01 March 2000

Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future.

scientific article

Nanosuspensions for the formulation of aphidicolin to improve drug targeting effects against leishmania infected macrophages.

scientific article published in March 2000

Nanosuspensions of poorly soluble drugs--reproducibility of small scale production.

scientific article published in March 2000

Natural products - modifying metabolite pathways in plants

scientific article published on 17 September 2013

Natural products as antiparasitic drugs.

scientific article

Natural products – learning chemistry from plants

scientific article published on March 2014

New ideas for new drug entities

scientific article published on 01 June 2003

New trichothecenes isolated from Holarrhena floribunda.

scientific article published in January 2000

Novel insights into plant-endophyte communication: maytansine as an example.

scientific article published on 14 December 2016

Ozone pretreatment of process waste water generated in course of fluoroquinolone production

scientific article published on 12 July 2017

Perspectives and limits of engineering the isoprenoid metabolism in heterologous hosts.

scientific article published on 11 August 2009

Petunia hybrida PDR2 is involved in herbivore defense by controlling steroidal contents in trichomes

scientific article published on 15 September 2016

Pharmacological profile of extracts of Pelargonium sidoides and their constituents.

scientific article published in January 2003

Pneumocystis carinii synthesizes four ubiquinone homologs: inhibition by atovaquone and bupravaquone but not by stigmatellin

scientific article published in January 2001

Potential antibiotic and anti-infective effects of rhodomyrtone from Rhodomyrtus tomentosa (Aiton) Hassk. on Streptococcus pyogenes as revealed by proteomics

scientific article published on 25 March 2011

Preliminary evidence for a mitochondrion in Cryptosporidium parvum: phylogenetic and therapeutic implications

scientific article published on 01 September 1999

Proanthocyanidins and related compounds: antileishmanial activity and modulatory effects on nitric oxide and tumor necrosis factor-alpha-release in the murine macrophage-like cell line RAW 264.7.

scientific article

Production and characterisation of mucoadhesive nanosuspensions for the formulation of bupravaquone

scientific article

Production of justicidin B, a cytotoxic arylnaphthalene lignan from genetically transformed root cultures of Linum leonii

scientific article published on July 2006

Production of Δ9-tetrahydrocannabinolic acid from cannabigerolic acid by whole cells of Pichia (Komagataella) pastoris expressing Δ9-tetrahydrocannabinolic acid synthase from Cannabis sativa L.

scientific article

Production of α-cuprenene in Xanthophyllomyces dendrorhous: a step closer to a potent terpene biofactory

scientific article

Quantitative and qualitative investigation of Duboisia myoporoides R.BR.

scientific article

Rhodomyrtone: a new candidate as natural antibacterial drug from Rhodomyrtus tomentosa

scientific article published on 19 March 2009

Seasonal variations in the deoxypodophyllotoxin content and yield of Anthriscus sylvestris L. (Hoffm.) grown in the field and under controlled conditions

scientific article published on 18 July 2011

Solid lipid nanoparticles for parenteral drug delivery.

scientific article published on May 2004

Stable biocompatible adjuvants--a new type of adjuvant based on solid lipid nanoparticles: a study on cytotoxicity, compatibility and efficacy in chicken.

scientific article published on July 2002

Structure-cytotoxicity relationships of a series of natural and semi-synthetic simple coumarins as assessed in two human tumour cell lines

scientific article published on March 1997

Tannins and related compounds: killing of amastigotes of Leishmania donovani and release of nitric oxide and tumour necrosis factor alpha in macrophages in vitro.

scientific article

Taxomyces andreanae: a presumed paclitaxel producer demystified?

scientific article

The Phytochemical and Biological Investigation of Jatropha pelargoniifolia Root Native to the Kingdom of Saudi Arabia

scientific article published on 28 July 2018

The impact of nanobiotechnology on the development of new drug delivery systems.

scientific article

The molecular cloning of dihydroartemisinic aldehyde reductase and its implication in artemisinin biosynthesis in Artemisia annua

scientific article published on 19 May 2010

The phytochemical profile and identification of main phenolic compounds from the leaf exudate of Aloe secundiflora by high-performance liquid chromatography-mass spectroscopy

scientific article

The role of plasma proteins in brain targeting: species dependent protein adsorption patterns on brain-specific lipid drug conjugate (LDC) nanoparticles.

scientific article

Traditional use of ethnomedicinal native plants in the Kingdom of Saudi Arabia

article

Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production

article

Ubiquinone synthesis and its regulation in Pneumocystis carinii

scientific article published on 01 November 2006

[Chemotherapy of leishmaniasis and human trypanosomiasis: status and new developments]

scientific article published on 01 July 1999

List of works by Oliver Kayser

1H NMR based metabolite profiling with special focus on tropane alkaloids in Duboisia species

A new approach for targeting to Cryptosporidium parvum using mucoadhesive nanosuspensions: research and applications

Amphotericin B.

An endophytic fungus Phyllosticta capitalensis harboring uncultivable endosymbiotic bacterium Herbaspirillum sp. produces lactam-fused 4-pyrones

Anti-cancer and antibacterial trioxacarcins with high anti-malaria activity from a marine Streptomycete and their absolute stereochemistry

Antibacterial Activity of Rhodomyrtus tomentosa (Aiton) Hassk. Leaf Extract against Clinical Isolates of Streptococcus pyogenes

Antibacterial Azaphilones from an Endophytic Fungus, Colletotrichum sp. BS4. ⬇️

Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme

Antibacterial activity of simple coumarins: structural requirements for biological activity.

Antileishmanial activities of aphidicolin and its semisynthetic derivatives

Antileishmanial activity of hydrolyzable tannins and their modulatory effects on nitric oxide and tumour necrosis factor-alpha release in macrophages in vitro.

Antileishmanial activity of piceatannol isolated from Euphorbia lagascae seeds.

Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae).

Antileishmanial structure-activity relationships of synthetic phospholipids: in vitro and in vivo activities of selected derivatives

Antimicrobial, antitumor and antileishmania screening of medicinal plants from Guinea-Bissau

Antiparasitic activity of marine pyridoacridone alkaloids related to the ascididemins

Aurones interfere with Leishmania major mitochondrial fumarate reductase

Biocontrol potential of endophytes harbored in Radula marginata (liverwort) from the New Zealand ecosystem

Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4.

Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast

Characterization of nebulized buparvaquone nanosuspensions--effect of nebulization technology

Combinatorial biosynthesis of medicinal plant secondary metabolites

Conformational sampling for large-scale virtual screening: accuracy versus ensemble size.

Cytotoxicity studies of Dynasan 114 solid lipid nanoparticles (SLN) on RAW 264.7 macrophages-impact of phagocytosis on viability and cytokine production

Delivery of amphotericin B nanosuspensions to the brain and determination of activity against Balamuthia mandrillaris amebas

Delivery strategies for antiparasitics.

Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using 1H NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis

Elucidation of structure-function relationship of THCA and CBDA synthase from Cannabis sativaL

Endophytes are hidden producers of maytansine in Putterlickia roots

Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid

Enhancement of antimicrobial activity of tannins and related compounds by immune modulatory effects.

Evaluation of in vitro activity of aurones and related compounds against Cryptosporidium parvum

Evaluation of in vitro and in vivo activity of benzindazole-4,9-quinones against Cryptosporidium parvum

Evaluation of the antimicrobial potency of tannins and related compounds using the microdilution broth method

Formulation of amphotericin B as nanosuspension for oral administration

Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis

Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania major-infected macrophage-like RAW 264.7 cells treated with gallic acid

HPLC detection of miltefosine using an evaporative light scattering detector.

HPLC-photodiode array detection analysis of curcuminoids in Curcuma species indigenous to Indonesia

Heavy metal contamination of nanosuspensions produced by high-pressure homogenisation

Heterologous expression of pentalenene synthase (PSS) from Streptomyces UC5319 in Xanthophyllomyces dendrorhous.

Identification of lignans and related compounds in Anthriscus sylvestris by LC-ESI-MS/MS and LC-SPE-NMR.

Immunomodulatory principles of Pelargonium sidoides

In Vivo Validation of In Silico Predicted Metabolic Engineering Strategies in Yeast: Disruption of α-Ketoglutarate Dehydrogenase and Expression of ATP-Citrate Lyase for Terpenoid Production

In silico profiling of Escherichia coli and Saccharomyces cerevisiae as terpenoid factories.

In vitro activity of aurones against Plasmodium falciparum strains K1 and NF54.

In vitro leishmanicidal activity of aurones

In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones

In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones.

In vitro leishmanicidal activity of naturally occurring chalcones

In vitro regeneration of wild chervil (Anthriscus sylvestris L.).

Inhibition of mutagenesis of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) by coumarins and furanocoumarins, chromanones and furanochromanones.

Leishmanicidal activity of aurones

Leishmanicidal and antiplasmodial activity of constituents of Smirnowia iranica

Lignans from cell suspension cultures of Phyllanthus niruri, an Indonesian medicinal plant.

Lipase degradation of Dynasan 114 and 116 solid lipid nanoparticles (SLN)--effect of surfactants, storage time and crystallinity

Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption

Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate

Metabolic stereoselectivity of cytochrome P450 3A4 towards deoxypodophyllotoxin: In silico predictions and experimental validation

Molecular cloning and characterization of a broad substrate terpenoid oxidoreductase from Artemisia annua

Monitoring Metabolite Profiles of Cannabis sativa L. Trichomes during Flowering Period Using 1H NMR-Based Metabolomics and Real-Time PCR.

Nanosuspensions as a new approach for the formulation for the poorly soluble drug tarazepide

Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future.

Nanosuspensions for the formulation of aphidicolin to improve drug targeting effects against leishmania infected macrophages.

Nanosuspensions of poorly soluble drugs--reproducibility of small scale production.

Natural products - modifying metabolite pathways in plants

Natural products as antiparasitic drugs.

Natural products – learning chemistry from plants

New ideas for new drug entities

New trichothecenes isolated from Holarrhena floribunda.

Novel insights into plant-endophyte communication: maytansine as an example.

Ozone pretreatment of process waste water generated in course of fluoroquinolone production

Perspectives and limits of engineering the isoprenoid metabolism in heterologous hosts.

Petunia hybrida PDR2 is involved in herbivore defense by controlling steroidal contents in trichomes

Pharmacological profile of extracts of Pelargonium sidoides and their constituents.

Pneumocystis carinii synthesizes four ubiquinone homologs: inhibition by atovaquone and bupravaquone but not by stigmatellin

Potential antibiotic and anti-infective effects of rhodomyrtone from Rhodomyrtus tomentosa (Aiton) Hassk. on Streptococcus pyogenes as revealed by proteomics

Preliminary evidence for a mitochondrion in Cryptosporidium parvum: phylogenetic and therapeutic implications

Proanthocyanidins and related compounds: antileishmanial activity and modulatory effects on nitric oxide and tumor necrosis factor-alpha-release in the murine macrophage-like cell line RAW 264.7.