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List of works by Elena Cattaneo

A DNA transposon-based approach to functional screening in neural stem cells.

scientific article published on 3 August 2010

A gene network regulating lysosomal biogenesis and function

scientific article

A microRNA-based gene dysregulation pathway in Huntington's disease

scientific article

A short term analysis of the behaviour of conditionally immortalized neuronal progenitors and primary neuroepithelial cells implanted into the fetal rat brain.

scientific article published on December 1994

A transgenic minipig model of Huntington's Disease

scientific article published in January 2013

Aberrant A2A receptor function in peripheral blood cells in Huntington's disease

scientific article published on 4 September 2003

Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin

scientific article published on May 2001

Activated estrogen receptor mediates growth arrest and differentiation of a neuroblastoma cell line

scientific article

Activation of the JAK/STAT pathway leads to proliferation of ST14A central nervous system progenitor cells

scientific article published on September 1996

Adaptation of NS cells growth and differentiation to high-throughput screening-compatible plates

scientific article

Adrenal ganglioneuroma with multifocal retroperitoneal extension: a challenging diagnosis

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

scientific article published in May 2012

An optimized experimental strategy for efficient conversion of embryonic stem (ES)-derived mouse neural stem (NS) cells into a nearly homogeneous mature neuronal population

scientific article

Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease

scientific article published on 23 December 2008

Apoptosome inactivation rescues proneural and neural cells from neurodegeneration.

scientific article published in November 2004

Auditory hallucinations in a 15-year-old boy: an unusual presentation of hypothyroidism ⬇️

scientific article published on July 14, 2009

Basal ganglia precursors found in aggregates following embryonic transplantation adopt a striatal phenotype in heterotopic locations ⬇️

scientific article published on August 1, 1998

Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models

scientific article published on 19 July 2013

Biological abnormalities of peripheral A(2A) receptors in a large representation of polyglutamine disorders and Huntington's disease stages

scientific article

Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347.

scientific article published on 10 May 2008

Brain cytochromes P-450 are responsive to phenobarbital and tricyclic amines

scientific article

Brain-derived neurotrophic factor in neurodegenerative diseases

scientific article

Brain-derived neurotrophic factor in patients with Huntington's disease

scientific article

CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice

scientific article

Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease

scientific article published on 21 December 2007

Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons

scientific article published on 27 August 2002

Changes in beta amyloid precursor protein secretion associated with the proliferative status of CNS derived progenitor cells

scientific article published on July 1996

Characterization of a p75(NTR) apoptotic signaling pathway using a novel cellular model

scientific article

Characterization, developmental expression and evolutionary features of the huntingtin gene in the amphioxus Branchiostoma floridae.

scientific article

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

scientific article

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

scientific article

Cholesterol dysfunction in neurodegenerative diseases: is Huntington's disease in the list?

scientific article published on 25 October 2006

Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice

scientific article published on 20 November 2015

Chromatin dysfunction in Huntington's disease

scientific article

Ciliary neurotrophic factor may activate mature astrocytes via binding with the leukemia inhibitory factor receptor

scientific article published in February 2001

Ciliary neurotrophic factor overexpression in neural progenitor cells (ST14A) increases proliferation, metabolic activity, and resistance to stress during differentiation

scientific article published on January 2003

Ciliary neurotrophic factor overexpression in neural progenitor cells (ST14A) increases proliferation, metabolic activity, and resistance to stress during differentiation

article published in 2004

Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain

scientific article published on September 2003

Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain

scientific article published on January 2005

Controlling neural stem cell division within the adult subventricular zone: an APPealing job.

scientific article

Corrigendum to “Whole body cholesterol metabolism is impaired in Huntington's disease” [Neurosci. Lett. 494 (2011) 245–249]

scholarly article published in Neuroscience Letters

Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions.

scientific article published on 8 December 2007

Cortical-Striatal Dysfunction in Huntington's Disease

Depletion of wild-type huntingtin in mouse models of neurologic diseases

scientific article published in October 2003

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

scientific article published in January 2013

Differentiating embryonic stem-derived neural stem cells show a maturation-dependent pattern of voltage-gated sodium current expression and graded action potentials

scientific article published on 20 July 2007

Differentiation of human telencephalic progenitor cells into MSNs by inducible expression of Gsx2 and Ebf1.

scientific article published on 30 January 2017

Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.

scientific article

Do amniotic fluid-derived stem cells differentiate into neurons in vitro?

scientific article published in March 2008

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

scientific article published in November 2000

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

scientific article published in October 2005

Dysfunction of wild-type huntingtin in Huntington disease

scientific article (publication date: February 2003)

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

scientific article (publication date: 26 November 2003)

EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs

scientific article published on 4 February 2013

Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice

scientific article published on 29 November 2016

Early and transient alteration of adenosine A2A receptor signaling in a mouse model of Huntington disease

scientific article

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

scientific article published in August 2002

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

scientific article published on 21 November 2014

Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain

scientific article published in November 1998

Emerging roles for cholesterol in Huntington's disease ⬇️

scientific article published on July 19, 2011

ErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1beta1-induced migration

scientific journal article

Erratum to “Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain”

scholarly article published in Neuroscience

Erratum to: Preservation of positional identity in fetus-derived neural stem (NS) cells from different mouse central nervous system compartments

scientific article published on 01 August 2016

Erratum: Neural stem cell systems: physiological players or in vitro entities?

scholarly article published in Nature Reviews Neuroscience

Evaluating test statistics to select interesting genes in microarray experiments

scientific article published on September 2002

Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model

scientific article

Executive dysfunction and avoidant personality trait in myotonic dystrophy type 1 (DM-1) and in proximal myotonic myopathy (PROMM/DM-2).

scientific article

Expressed Alu repeats as a novel, reliable tool for normalization of real-time quantitative RT-PCR data

scientific article

Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain

scientific article

Expression of the JAK and STAT superfamilies in human meningiomas

scientific article published in September 1999

Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes

scientific article

Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop

scientific article

Freshly dissociated fetal neural stem/progenitor cells do not turn into blood

scientific article published in February 2003

From target identification to drug screening assays for neurodegenerative diseases

G-Force PD: a global initiative in coordinating stem cell-based dopamine treatments for Parkinson's disease

scientific article published on 24 September 2015

Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation

scientific article published in July 2003

Gene therapy of experimental brain tumors using neural progenitor cells

scientific article published in April 2000

Gene therapy using neural stem cells

scientific article published on January 2002

Generation and characterization of embryonic striatal conditionally immortalized ST14A cells ⬇️

scientific article published on July 15, 1998

Genome-Wide Definition of Promoter and Enhancer Usage during Neural Induction of Human Embryonic Stem Cells.

scientific article published on 15 May 2015

Growth hormone regulation of growth hormone-releasing hormone gene expression

article

HTLV-II infection in Italian drug abusers

scientific article published in September 1990

High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.

scientific article

Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease

scientific article

Human cytomegalovirus pUL10 interacts with leukocytes and impairs TCR-mediated T-cell activation

scientific article published on 19 May 2016

Human pluripotent stem cell differentiation into authentic striatal projection neurons

scientific article published in August 2013

Huntingtin gene CAG repeat size affects autism risk: Family-based and case-control association study

scientific article published on 11 July 2020

Huntingtin gene evolution in Chordata and its peculiar features in the ascidian Ciona genus

scientific article published on 8 November 2006

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

scientific article (publication date: September 2003)

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

scientific article published on 5 March 2001

Huntington's disease

scientific article published in January 2014

IL-4 gene transfer for the treatment of experimental gliomas

scientific article published on January 1998

Identifying and manipulating neuronal stem cells

scientific article published on August 1991

In vitro and in vivo models of Huntington's disease show alterations in the endocannabinoid system

scientific journal article

In vitro characterization of embryionic ST14A-cells

scientific article published on November 2008

In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice

scientific article published on 15 November 2012

Induced pluripotent stem cell lines from Huntington's disease mice undergo neuronal differentiation while showing alterations in the lysosomal pathway

scientific article published on 28 December 2011

Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease

scientific article

Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells

scientific article

Introduction

Investigating DNA methylation dynamics and safety of human embryonic stem cell differentiation toward striatal neurons

scientific article

Italy's stem-cell challenge gaining momentum

scientific article published in Nature

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

scientific article

Limited efficacy of the HSV-TK/GCV system for gene therapy of malignant gliomas and perspectives for the combined transduction of the interleukin-4 gene

scientific article

Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture

scientific article

Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators

scientific article

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

scientific article (publication date: 20 July 2001)

Loss of normal huntingtin function: new developments in Huntington's disease research

scientific article

Members of the JAK/STAT proteins are expressed and regulated during development in the mammalian forebrain

scientific article published in November 1998

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis

scientific article

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

scientific article published on 20 August 2003

Modeling Huntington's disease in cells, flies, and mice

scientific article

Modeling brain pathologies using neural stem cells

scientific article published in January 2002

Modifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma

scientific article published on 7 May 2015

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease ⬇️

scientific article published on July 1, 2010

Molecular and functional definition of the developing human striatum

scientific article published on 10 November 2014

Molecular classification of breast carcinomas using tissue microarrays

scientific article

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

scientific article

Mutant huntingtin goes straight to the heart

scientific article

NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease

scientific article published on 10 July 2012

Neural stem and progenitor cells: choosing the right Shc.

scientific article published on January 2004

Neural stem cell systems: diversities and properties after transplantation in animal models of diseases

scientific article published on April 2006

Neural stem cell systems: physiological players or in vitro entities?

scientific article published on 28 January 2010

Neural stem cells engrafted in the adult brain fuse with endogenous neurons

scientific article published on 20 November 2012

Neural stem cells: a pharmacological tool for brain diseases?

scientific article

Neural-specific inactivation of ShcA functions results in anatomical disorganization of subventricular zone neural stem cell niche in the adult brain

scientific article published on 10 March 2010

Neurologic Diseases

Neuropotent self-renewing neural stem (NS) cells derived from mouse induced pluripotent stem (iPS) cells

article

Neuroprotection and brain cholesterol biosynthesis in Huntington's disease

scientific article published on 31 August 2010

New ISSCR guidelines underscore major principles for responsible translational stem cell research

scientific article published on December 2008

Niche-independent symmetrical self-renewal of a mammalian tissue stem cell

scientific article

No evidence of association between BDNF gene variants and age-at-onset of Huntington's disease

scientific article published on 14 August 2006

Non-virally mediated gene transfer into human central nervous system precursor cells.

scientific article

Normal huntingtin function: an alternative approach to Huntington's disease

scientific article

Novel and immortalization-based protocols for the generation of neural CNS stem cell lines for gene therapy approaches

scientific article

Novel neural stem cell systems

Opinion: neural stem cell therapy for neurological diseases: dreams and reality

scientific article

Patients Beware: Commercialized Stem Cell Treatments on the Web

scientific article published on 17 June 2010

Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease

scientific article published on June 2011

Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation

scientific article

Phylogenetic comparison of huntingtin homologues reveals the appearance of a primitive polyQ in sea urchin

scientific article published on 28 November 2007

Pitfalls in the detection of cholesterol in Huntington's disease models

scientific article

Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease.

scientific article published on 4 September 2008

Prediction of adherence to antiretroviral therapy: can patients' gender play some role? An Italian pilot study

scientific article published in May 2008

Preservation of positional identity in fetus-derived neural stem (NS) cells from different mouse central nervous system compartments.

scientific article published on 28 October 2010

Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease

scientific article published on August 2005

Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease.

scientific article

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

scientific article published in August 2005

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor

scientific article

Proteasome activator enhances survival of Huntington's disease neuronal model cells

scientific article published on 28 February 2007

Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death

scientific article

REST controls self-renewal and tumorigenic competence of human glioblastoma cells

scientific article

Radial glia and neural specification

article published in 2007

Regulation of stem cell therapies under attack in Europe: for whom the bell tolls

scientific article published on 3 May 2013

Repressor element-1 silencing transcription factor (REST) is present in human control and Huntington's disease neurones

scientific article published in December 2014

Rescue of gene expression by modified REST decoy oligonucleotides in a cellular model of Huntington's disease

scientific article

Retroviral-mediated transfer of the galactocerebrosidase gene in neural progenitor cells

scientific article published on December 1998

Role of brain-derived neurotrophic factor in Huntington's disease

scientific article published on 9 February 2007

Ruvalcaba syndrome: a case report

scientific article published in September 1984

SAR and QSAR study on 2-aminothiazole derivatives, modulators of transcriptional repression in Huntington's disease

scientific article

ST14A cells have properties of a medium-size spiny neuron.

scientific article

STAT signalling in the mature and aging brain

scientific article published in July 2000

SUMO modification of Huntingtin and Huntington's disease pathology

scientific article

Science and politics. An interview with Elena Cattaneo, Director of the Centre for Stem Cell Research at the University of Milano, Italy. Interview by Marta Paterlini

scientific article published on 03 December 2010

Science under politics. An Italian nightmare

scientific article

Selective in vitro blockade of neuroepithelial cells proliferation by methylazoxymethanol, a molecule capable of inducing long lasting functional impairments

scientific article published on 01 August 1995

Selective inhibitors of death in mutant huntingtin cells

scientific article published on 31 December 2006

Setting the conditions for efficient, robust and reproducible generation of functionally active neurons from adult subventricular zone-derived neural stem cells

scientific article

Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington's disease mutation in peripheral lymphocytes.

scientific article published on 6 May 2007

Sex-specific effects of the Huntington gene on normal neurodevelopment

scientific article published in January 2017

Shc signaling in differentiating neural progenitor cells

scientific article

Shc3 affects human high-grade astrocytomas survival

scientific article

Signalling from tyrosine kinases in the developing neurons and glia of the mammalian brain

scientific article

Signalling through the JAK-STAT pathway in the developing brain

scientific article

Stamina therapies: Let the record stand

scientific article published in Nature

Stem Cells for neurodegenerative diseases: Hopes and reality

Stem cells: Taking a stand against pseudoscience

scientific article published in Nature

Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice

scientific article published on 22 September 2020

Survival, integration, and differentiation of neural stem cell lines after transplantation to the adult rat striatum

scientific article published on June 1997

Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease

scientific article

Systematic chromosomal analysis of cultured mouse neural stem cell lines

scientific article published on 12 March 2011

Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells

scientific article

The Huntington's Paradox

scientific article published in July 2016

The enigma of Huntington's disease.

scientific article published in December 2002

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities

scientific article published on 01 January 2022

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

scientific article

The function of the neuronal proteins Shc and huntingtin in stem cells and neurons: pharmacologic exploitation for human brain diseases

scientific article

The neurotoxicity of mutant proteins 20 years after the discovery of the first mutant gene involved in neurodegeneration. Foreword.

scientific article published in May 2012

The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease

scientific article published on 17 February 2010

Therapeutic potential of neural stem cells: greater in people's perception than in their brains?

scientific article

Time to change the single-centre approach to management of patients with tuberculosis: a novel network platform with automatic data import and data sharing

scientific article published in January 2018

Transplantation of prodrug-converting neural progenitor cells for brain tumor therapy

scientific article published on May 2003

Turning REST/NRSF dysfunction in Huntington's disease into a pharmaceutical target

scientific article published on January 2009

Whole body cholesterol metabolism is impaired in Huntington's disease.

scientific article published on 22 March 2011

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

scientific article

Wnt-5a expression in the rat neuronal progenitor cell line ST14A.

scientific article published on 20 April 2004

Wnt5a is a transcriptional target of Dlx homeogenes and promotes differentiation of interneuron progenitors in vitro and in vivo.

scientific article

c-fos induction by estrogen in specific rat brain areas

scientific article published on March 1990

iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF.

scientific article published in January 2013

mSEL-1L (Suppressor/enhancer Lin12-like) protein levels influence murine neural stem cell self-renewal and lineage commitment

scientific article published on 31 March 2011

p66(ShcA) adaptor molecule accelerates ES cell neural induction

scientific article

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