Search filters

List of works by Françoise Gisou van der Goot

A 'molten-globule' membrane-insertion intermediate of the pore-forming domain of colicin A

scientific article published on 01 December 1991

A bacterial big-MAC attack

scientific article published in December 2004

A pore-forming toxin interacts with a GPI-anchored protein and causes vacuolation of the endoplasmic reticulum.

scientific article

A rivet model for channel formation by aerolysin-like pore-forming toxins

scientific article

A toxic palmitoylation of Cdc42 enhances NF-κB signaling and drives a severe autoinflammatory syndrome

scientific article published on 10 April 2020

About lipids and toxins

scientific article published on 28 August 2006

Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo.

scientific article

Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes.

scientific article

Aerolysin Induces G-protein Activation and Ca2+Release from Intracellular Stores in Human Granulocytes ⬇️

scientific article published on July 17, 1998

Aerolysin and related Aeromonas toxins

article

Aerolysin from Aeromonas hydrophila and related toxins

scientific article

Aerolysin--a paradigm for membrane insertion of beta-sheet protein toxins?

scientific article published in January 1998

Aerolysin--the ins and outs of a model channel-forming toxin.

scientific article

Akt Is S-Palmitoylated: A New Layer of Regulation for Akt

scientific article published on 15 February 2021

All in the family: the toxic activity of pore-forming colicins.

scientific article published on February 1994

Analysis of glycosyl phosphatidylinositol-anchored proteins by two-dimensional gel electrophoresis

Anthrax toxin receptor 2a controls mitotic spindle positioning

scientific article

Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes

article published in the Proceedings of the National Academy of Sciences of the United States of America

Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process

scientific article

Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake.

scientific article

Anthrax toxin: the long and winding road that leads to the kill

scientific article

Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts

scientific article

Bacterial invasion via lipid rafts.

scientific article

Bacterial pore-forming toxins: the (w)hole story?

scientific article

Bacterial subversion of lipid rafts.

scientific article published on February 2004

Binding of Lassa virus perturbs extracellular matrix-induced signal transduction via dystroglycan.

scientific article published on 04 April 2012

Biochemical membrane lipidomics during Drosophila development.

scientific article published on 20 December 2012

CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome ⬇️

scientific article

Calnexin controls the STAT3-mediated transcriptional response to EGF.

scientific article published on August 2013

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

scientific article

Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

scientific journal article

Close encounter of the third kind: the ER meets endosomes at fission sites

scientific article published on 01 December 2014

Clustering induces a lateral redistribution of alpha 2 beta 1 integrin from membrane rafts to caveolae and subsequent protein kinase C-dependent internalization.

scientific article

Conformational Changes in Aerolysin during the Transition from the Water-Soluble Protoxin to the Membrane Channel ⬇️

scientific article published on December 9, 1997

Conformational changes due to membrane binding and channel formation by staphylococcal alpha-toxin

scientific article published on 01 February 1997

Converging physiological roles of the anthrax toxin receptors

scientific article published on 12 August 2019

Conversion of a transmembrane to a water-soluble protein complex by a single point mutation

scientific article published on 01 October 2002

Cross-talk between caveolae and glycosylphosphatidylinositol-rich domains.

scientific article published on 13 June 2001

Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process.

scientific article

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone.

scientific article published on 25 January 2016

Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux.

scientific article

Determination of solute reflection coefficients in kidney brush-border membrane vesicles by light scattering: influence of the refractive index

scientific article published on 01 February 1989

Did Cholera Toxin Finally Get Caught? ⬇️

scientific article published on May 15, 2013

Differential dependence on N-glycosylation of anthrax toxin receptors CMG2 and TEM8

scientific article published on 17 March 2015

Differential sorting and fate of endocytosed GPI-anchored proteins

scientific article

Dimerization stabilizes the pore-forming toxin aerolysin in solution ⬇️

scientific article published on August 25, 1993

Diversity of raft-like domains in late endosomes

scientific article

Dual chaperone role of the C-terminal propeptide in folding and oligomerization of the pore-forming toxin aerolysin

scientific article (publication date: July 2011)

Dynamic Radiolabeling of S-Palmitoylated Proteins

scientific article published on 01 January 2019

Dynamics of GPI-anchored proteins on the surface of living cells.

scientific article published in March 2006

Dynamics of unfolded protein transport through an aerolysin pore.

scientific article published on 14 February 2011

Elastic membrane heterogeneity of living cells revealed by stiff nanoscale membrane domains

scientific article

Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors

scientific article

Eukaryotic cells and microbial pathogens: a familiar couple take centre stage

scientific article published on 01 January 2003

Evidence for permanent water channels in the basolateral membrane of an ADH-sensitive epithelium ⬇️

scientific article published on February 1, 1991

Exotoxin secretion: getting out to find the way in.

scientific article published in January 2008

Extending the aerolysin family: from bacteria to vertebrates

scientific article

Flow cytometry and sorting of amphibian bladder endocytic vesicles containing ADH-sensitive water channels

scientific article published on 01 June 1992

Functional interactions between anthrax toxin receptors and the WNT signalling protein LRP6.

scientific article

Getting the Opportunity to Fly on your own.

scientific article published in December 2009

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Harnessing the Membrane Translocation Properties of AB Toxins for Therapeutic Applications

scientific article published on 06 January 2021

Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20

scientific article published on 01 January 2020

Hijacking multivesicular bodies enables long-term and exosome-mediated long-distance action of anthrax toxin

scientific article

How many lives does CLIMP-63 have?

scientific article

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

scientific article

Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade.

scientific article

Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux

scientific article published on 19 December 2019

In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy.

scientific article published on 19 April 2013

Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction

scientific article

Intra-endosomal membrane traffic

scientific article published on September 2006

Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction

scientific article

Introduction: brief historical overview

scientific article published on 01 January 2014

Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure

scientific article published on 24 January 2007

Kicking Out Pathogens in Exosomes

scientific article published on June 2015

Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking

scientific article

Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis

scientific article published on 01 May 2020

Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging

scientific article

Local and substrate-specific S-palmitoylation determines subcellular localization of Gαo

scientific article published on 19 April 2022

Mammalian membrane trafficking as seen through the lens of bacterial toxins

scientific article published on 01 April 2020

Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin

scientific article

Mechanisms of pathogen entry through the endosomal compartments

scientific article (publication date: July 2006)

Mechanistic effects of protein palmitoylation and the cellular consequences thereof.

scientific article published on 15 February 2014

Membrane injury by pore-forming proteins.

scientific article published on 11 May 2009

Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway

scientific article

Membrane insertion: The strategies of toxins (review).

scientific article

Membrane interaction of TNF is not sufficient to trigger increase in membrane conductance in mammalian cells

scientific article published on 01 October 1999

Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins.

scholarly article

Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin

scientific article

Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism

scientific article

Movement of a Loop in Domain 3 of Aerolysin Is Required for Channel Formation†

scientific article published on 01 January 1998

Novel ubiquitin-dependent quality control in the endoplasmic reticulum.

scientific article published on 23 July 2009

Oiling the key hole.

scientific article

Oiling the wheels of the endocytic pathway

scientific article published on 01 July 2002

Palmitoylated calnexin is a key component of the ribosome-translocon complex

scientific article

Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum

scholarly article

Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion

scientific article published on 10 December 2018

Palmitoylation of membrane proteins (Review).

scientific article published on 10 December 2008

Palmitoylation, pathogens and their host

scientific article published on February 2013

Pathogenic pore-forming proteins: function and host response.

scientific article published on September 2012

Pathogens, toxins, and lipid rafts

article published in 2000

Physical and chemical characterization of the oligomerization state of the Aeromonas hydrophila lipase/acyltransferase

scientific article published on 01 November 1993

Plasma membrane microdomains act as concentration platforms to facilitate intoxication by aerolysin

scientific article

Plasticity of the transmembrane beta-barrel.

scientific article

Pore formation: an ancient yet complex form of attack.

scientific article published on 12 February 2008

Pore-forming toxins and cellular non-immune defenses (CNIDs).

scientific article published on 17 January 2007

Pore-forming toxins induce multiple cellular responses promoting survival.

scientific article published on 26 April 2011

Pore-forming toxins: ancient, but never really out of fashion

scientific article

Preliminary crystallographic analysis of two oligomerization-deficient mutants of the aerolysin toxin, H132D and H132N, in their proteolyzed forms

scientific article

Purification and Analysis of Authentic CLIP-170 and Recombinant Fragments

scientific article published in Journal of Biological Chemistry

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

scientific article

Receptors of anthrax toxin and cell entry.

scientific article

Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization

scientific article

Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin.

scientific article

Revealing Assembly of a Pore-Forming Complex Using Single-Cell Kinetic Analysis and Modeling.

scientific article published on April 2016

Role of acidic lipids in the translocation and channel activity of colicins A and N in Escherichia coli cells ⬇️

scientific article published on April 1, 1993

Sensitivity of polarized epithelial cells to the pore-forming toxin aerolysin.

scientific article

Separation of early steps in endocytic membrane transport ⬇️

scientific article published on December 1, 1997

Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy

scientific article published on 01 August 2009

Sliding doors: clathrin-coated pits or caveolae? ⬇️

scientific article published on May 1, 2003

Spectroscopic study of the activation and oligomerization of the channel-forming toxin aerolysin: identification of the site of proteolytic activation.

scientific article published in September 1992

Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family.

scientific article published on 24 October 2017

Structure and assembly of pore-forming proteins.

scientific article published on 19 February 2010

SwissPalm 2: Protein S-Palmitoylation Database

scientific article published on 01 January 2019

SwissPalm: Protein Palmitoylation database.

scientific article published on 16 July 2015

Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum.

scientific article published in April 2009

Targeting STING with covalent small-molecule inhibitors

scientific article published in Nature

The 2DX robot: A membrane protein 2D crystallization Swiss Army knife

article

The Ins and Outs of Anthrax Toxin

scientific article

The Pore-forming Toxin Proaerolysin Is Activated by Furin ⬇️

scientific article published in Journal of Biological Chemistry

The SwissLipids knowledgebase for lipid biology

scientific article published on 5 May 2015

The dark sides of capillary morphogenesis gene 2.

scientific article published on 6 December 2011

The glycan core of GPI-anchored proteins modulates aerolysin binding but is not sufficient: the polypeptide moiety is required for the toxin-receptor interaction.

scientific article published in February 2002

The lectin-like domain of tumor necrosis factor-α increases membrane conductance in microvascular endothelial cells and peritoneal macrophages

scientific article published on 01 October 1999

The molecular era of protein S-acylation: spotlight on structure, mechanisms, and dynamics

scientific article published on 12 July 2018

The role of the inflammasome in cellular responses to toxins and bacterial effectors

scientific article published on 06 September 2007

The tip of a molecular syringe

scientific article published on 01 September 1999

Toxoplasma: guess who's coming to dinner

scientific article published on 01 April 2006

Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6

scientific article published on 18 October 2016

What does S-palmitoylation do to membrane proteins?

scientific article published on 18 April 2013

When cells and microbes meet in Krakow

scientific article published on 25 February 2011

Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish

scientific article published on 03 July 2020

Paulina is supported by:

About Paulina

Help