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List of works by Hugo Van Aken

"You Live Life Going Forwards and Understand It Looking Backwards!" The Sixtieth Anniversary of the World Federation of Societies of Anaesthesiologists: 60 Years of Cooperation Between the International Anesthesia Research Society and the World Fede

scientific article published in October 2015

'Kids save lives': why schoolchildren should train in cardiopulmonary resuscitation

scientific article published on June 2015

6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice.

scientific article

A better understanding of ambulance personnel's attitude towards real-time resuscitation feedback

scientific article

A tribute to Dr. Paul A. J. Janssen: entrepreneur extraordinaire, innovative scientist, and significant contributor to anesthesiology

scientific article

A-type and B-type natriuretic peptides in cardiac surgical procedures

scientific article published in January 2004

Acute uremia but not renal inflammation attenuates aseptic acute lung injury: a critical role for uremic neutrophils

scientific article published on 11 October 2006

Affinity of carbon monoxide to hemoglobin increases at low oxygen fractions

scientific article published on 01 July 2002

Age- and procedure-specific differences of epidural analgesia in children--a database analysis

scientific article published on 19 January 2015

Amniotic air insufflation during minimally invasive fetoscopic fetal cardiac interventions is safe for the fetal brain in sheep

scientific article published on 01 September 2004

Are subspecialties and fellowship programs in German Anesthesia required?

scientific article published in July 2016

Arginine vasopressin compromises gut mucosal microcirculation in septic rats

scientific article

Arteriovenous carboxyhemoglobin difference in critical illness: fiction or fact?

scientific article published on 01 December 2002

Assessing analgesia in single and repeated administrations of propacetamol for postoperative pain: comparison with morphine after dental surgery

scientific article published in January 2004

Bradykinin-induced pulmonary vasoconstriction is time and inducible nitric oxide synthase dependent in a peritonitis sepsis model

scientific article

Bupivacaine inhibits thromboxane A2-induced vasoconstriction in rat thoracic aorta.

scientific article

Cardiopulmonary bypass during cardiac surgery modulates systemic inflammation by affecting different steps of the leukocyte recruitment cascade

scientific article

Cardiopulmonary resuscitation guidance improves medical students' adherence to guidelines in simulated cardiac arrest: a randomised cross-over study

scientific article

Cerebral response to norepinephrine compared with fluid resuscitation in ovine traumatic brain injury and systemic inflammation

scientific article published in October 2006

Cerebral vascular and metabolic response to sustained systemic inflammation in ovine traumatic brain injury

scientific article published in December 2004

Chemokine homeostasis vs. chemokine presentation during severe acute lung injury: the other side of the Duffy antigen receptor for chemokines

scientific article published on 08 January 2010

Chest compression quality management and return of spontaneous circulation: a matched-pair registry study

scientific article published on 30 March 2012

Congratulations from the IARS!

scientific article published on 01 October 2011

Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot study

scientific article published on 10 August 2009

Continuous thoracic epidural anesthesia improves gut mucosal microcirculation in rats with sepsis

scientific article published in November 2007

Continuous versus bolus infusion of terlipressin in ovine endotoxemia

scientific article published in November 2007

Continuously infused glipizide reverses the hyperdynamic circulation in ovine endotoxemia

scientific article published in June 2007

Cost containment in obstetric analgesia

scientific article published in January 2002

Dear levosimendan, the right ventricle will thank you!

scientific article published on 01 March 2007

Delayed onset of malignant hyperthermia in desflurane anesthesia

scientific article

Differential Effects of Selective and Nonselective Potassium Channel Inhibitors in Ovine Endotoxemic Shock (Macrocirculation) and in a Rat Model of Septic Shock (Microcirculation).

scientific article published on 2 February 2018

Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response

scientific article

Dobutamine reverses the vasopressin-associated impairment in cardiac index and systemic oxygen supply in ovine endotoxemia

scientific article published on January 2006

Does general anesthesia have a clinical impact on intraocular pressure in children?

scientific article

Dopexamine reverses the vasopressin-associated impairment in tissue oxygen supply but decreases systemic blood pressure in ovine endotoxemia

scientific article

Early multiple organ failure after recurrent endotoxemia in the presence of vasoconstrictor-masked hypovolemia

scientific article published in March 2003

Early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (The ELAIN-Trial): study protocol for a randomized controlled trial

scientific article published on 18 March 2016

Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial

scientific article published on 22 May 2016

Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial

scientific article

Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis

scientific article published on 01 January 2002

Effect of waxy maize-derived hydroxyethyl starch 130/0.4 on renal function in surgical patients

scientific article published on February 2013

Effects and limitations of an AED with audiovisual feedback for cardiopulmonary resuscitation

scientific article published on 01 October 2011

Effects of balanced crystalloid vs. 0.9% saline-based vs. balanced 6% tetrastarch infusion on renal function and tubular integrity in ovine endotoxemic shock

scientific article published on April 2011

Effects of combined arginine vasopressin and levosimendan on organ function in ovine septic shock.

scientific article published on October 2010

Effects of inhaled aerosolized iloprost and inhaled NO on pulmonary circulation and edema formation in ovine lung injury

scientific article published in July 2008

Effects of thoracic epidural anesthesia on hemodynamics and global oxygen transport in ovine endotoxemia

scientific article published in December 2006

Effects of titrated arginine vasopressin on hemodynamic variables and oxygen transport in healthy and endotoxemic sheep

scientific article published on May 2003

Effects of two different dosing regimens of terlipressin on organ functions in ovine endotoxemia

scientific article

Efficacy of intravenous paracetamol compared to dipyrone and parecoxib for postoperative pain management after minor-to-intermediate surgery: a randomised, double-blind trial ⬇️

scientific article published on February 1, 2011

Employing dobutamine as a useful agent to reverse the terlipressin-linked impairments in cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep

scientific article published in January 2008

Epidural anaesthesia and analgesia in mayor surgery.

scientific article published in August 2002

Epidural analgesia in sepsis: too early to judge a new concept

scientific article published on 24 September 2004

Erratum to: 'Early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (The ELAIN-Trial): study protocol for a randomized controlled trial'.

scientific article published on 23 May 2016

FGF23 signaling impairs neutrophil recruitment and host defense during CKD.

scientific article

Fetal plasma concentrations after intraamniotic sufentanil in chronically instrumented pregnant sheep

scientific article published in June 2003

Fluid resuscitation in the 21st century: don't try to run before you are able to walk

scientific article published on 17 July 2014

Fluid therapy in critical illness: a special focus on indication, the use of hydroxyethyl starch and its different raw materials

scientific article published on June 2013

Future challenges for anaesthesia departments. Introduction

scientific article published on September 2002

Glibenclamide dose response in patients with septic shock: effects on norepinephrine requirements, cardiopulmonary performance, and global oxygen transport

scientific article published on 01 November 2007

Guidelines on non-anaesthesiologist administration of propofol for gastrointestinal endoscopy ⬇️

scientific article published on August 1, 2011

Heat shock protein 72 and apoptosis indicate cardiac decompensation during early multiple organ failure in sheep

scientific article published on 24 February 2004

Helsinki Declaration on patient safety in anaesthesiology: Putting words into practice – Experience in Germany ⬇️

scientific article published on June 1, 2011

Hemodynamic effects of exogenous adrenomedullin in healthy and endotoxemic sheep

scientific article published in August 2002

Hemodynamic effects of thoracic epidural analgesia in ovine hyperdynamic endotoxemia

scientific article published in July 2007

Hemodynamic effects of titrated norepinephrine in healthy versus endotoxemic sheep

scientific article published in January 2007

Hemostasis and hemodilution: a quantitative mathematical guide for clinical practice

scientific article published in April 2003

Hepatitis after sevoflurane exposure in an infant suffering from primary hyperoxaluria type 1.

scientific article

High-molecular Hydroxyethyl Starch: Is More Data Still Needed?

scientific article published on 01 July 2015

Hydroxyethyl Starches

scientific article (publication date: July 2009)

IL-4 enhances hypoxia induced HIF-1alpha protein levels in human transformed intestinal cells

scientific article published on 3 November 2006

Impact of human albumin infusion on organ function in orthotopic liver transplantation--a retrospective matched-pair analysis

scientific article published on 05 December 2014

Impact of terlipressin on hepatosplanchnic perfusion: "only the dose makes a thing not a poison" (paracelsus).

scientific article published in April 2007

In response to "A multimodal postoperative rehabilitation program in critically ill diabetic patients"

scientific article published on 01 July 2002

Incidence of spinal haematoma after epidural puncture: analysis from the German network for safety in regional anaesthesia

scientific article

Inflammatory response and extracorporeal circulation

scientific article published on 27 March 2015

Infusion therapy in anaesthesia and intensive care: let's stop talking about 'wet' and 'dry'!

scientific article published in June 2009

Inhaled nitric oxide reduces lung edema during fluid resuscitation in ovine acute lung injury

scientific article published on 24 May 2003

Inhibitors of CXC chemokine receptor type 4: putative therapeutic approaches in inflammatory diseases

scientific article

Intensive care medicine: a multidisciplinary approach!

scientific article published on 01 May 2011

Intra-amniotic multimodal fetal echocardiography in sheep: a novel imaging approach during fetoscopic interventions and for assessment of high-risk pregnancies in which conventional imaging methods fail

scientific article published on 01 June 2002

Intravascular volume therapy with colloids in cardiac surgery

scientific article published on 14 August 2010

Is Anesthesia Dangerous? ⬇️

scientific article published on July 8, 2011

Is vasopressin increasing or decreasing mortality in patients with septic shock?

scientific article published in April 2008

Is vasopressin really superior to norepinephrine in reversing milrinone-induced vasodilation?

scientific article published on 30 August 2006

Kappa-opioid receptor antagonism improves recovery from myocardial stunning in chronically instrumented dogs

scientific article published in October 2006

Kids save lives--Training school children in cardiopulmonary resuscitation worldwide is now endorsed by the World Health Organization (WHO).

scientific article published on 21 July 2015

Kids save lives: a six-year longitudinal study of schoolchildren learning cardiopulmonary resuscitation: Who should do the teaching and will the effects last?

scientific article

Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study

scientific article published on 23 December 2010

Lidocaine reduces neutrophil recruitment by abolishing chemokine-induced arrest and transendothelial migration in septic patients

scientific article published on 29 November 2013

Long-term Effects of Remote Ischemic Preconditioning on Kidney Function in High-risk Cardiac Surgery Patients: Follow-up Results from the RenalRIP Trial

scientific article

Management of pulmonary hypertension: physiological and pharmacological considerations for anesthesiologists

scientific article

Management of right ventricular dysfunction in the perioperative setting

scientific article published on August 2014

Methylprednisolone reverses vasopressin hyporesponsiveness in ovine endotoxemia

scientific article published in March 2007

More attention to respiration: a simple but effective approach to reduce postoperative mortality?

scientific article published in March 2015

Naloxone improves splanchnic perfusion in conscious dogs through effects on the central nervous system

scientific article published on 01 February 2002

Nasotracheal intubation: a simple and effective technique to reduce nasopharyngeal trauma and tube contamination

scientific article published in November 2002

Nicotinamide increases systemic vascular resistance in ovine endotoxemia ⬇️

scientific article published on May 1, 2003

Our own blood is still the best thing to have in our veins

scientific article published on 01 October 2008

Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients

scientific article published on September 2002

Patient blood management--the new frontier

scientific article published on March 2013

Patient safety in anaesthesiology

scientific article published in June 2011

Perioperative Thromboseprophylaxe - Thrombozytenaggregationshemmer - Bedeutung für die Anästhesie

Perioperative mortality in Europe: intensive care saves lives ⬇️

scientific article published on December 12, 2012

Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled trial.

scientific article

Postoperative Akutschmerztherapie - Schwere Komplikationen durch Regionalanalgesieverfahren - Symptome, Diagnose und Therapie

scientific article published on 01 January 2007

Postoperative analgesia after knee surgery: a comparison of three different concentrations of ropivacaine for continuous femoral nerve blockade

scientific article published in July 2007

Prevention and treatment of major blood loss

scientific article published in September 2007

Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial

scientific article published on 21 January 2017

Provision of physiological data and reference values in awake and anaesthetized female sheep aged 6-12 months

scientific article

Rap1a activation by CalDAG‐GEFI and p38 MAPK is involved in E‐selectin‐dependent slow leukocyte rolling ⬇️

scientific article published on June 7, 2011

Re-evaluating currently available data and suggestions for planning randomised controlled studies regarding the use of hydroxyethyl starch in critically ill patients - a multidisciplinary statement

scientific article (publication date: 26 July 2013)

Recombinant factor VIIa and factor VIII treatment for acquired factor VIII deficiency: a case of repeated thrombotic endotracheal occlusion in a mechanically ventilated patient ⬇️

scientific article published on March 9, 2011

Regional anaesthesia and antithrombotic agents: recommendations of the European Society of Anaesthesiology.

scientific article published on December 2010

Relevance of non-albumin colloids in intensive care medicine

scientific article

Remote ischemic preconditioning and outcome: shall we all have an intermittent tourniquet?

scientific article

Renal effects of saline-based 10% pentastarch versus 6% tetrastarch infusion in ovine endotoxemic shock

scientific article published in April 2010

Reversible cardiac sympathectomy by high thoracic epidural anesthesia improves regional left ventricular function in patients undergoing coronary artery bypass grafting: a randomized trial

scientific article published in December 2003

Role of adenosine triphosphate-sensitive potassium channel inhibition in shock states: physiology and clinical implications

scientific article published on October 2007

Role of arginine vasopressin and terlipressin as first-line vasopressor agents in fulminant ovine septic shock

scientific article published on 10 April 2009

Role of atrial natriuretic peptide in pulmonary permeability and vasoregulation in ovine sepsis

scientific article published on 01 December 2004

Role of selective V1a receptor agonism in ovine septic shock.

scientific article published in January 2011

Role of selective V2-receptor-antagonism in septic shock: a randomized, controlled, experimental study

scientific article published on 5 November 2010

Role of vasopressinergic V1 receptor agonists in the treatment of perioperative catecholamine-refractory arterial hypotension.

scientific article published on June 2008

Schoolchildren as lifesavers in Europe - training in cardiopulmonary resuscitation for children

scientific article

Short-term administration of ethanol does not affect functional recovery from myocardial stunning in awake dogs

scientific article published in March 2003

Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep

scientific article published in November 2006

Short-term effects of phenylephrine on systemic and regional hemodynamics in patients with septic shock: a crossover pilot study.

scientific article published in April 2008

Single-lung ventilation for pulmonary lobe resection in a newborn

scientific article

Sleep disturbances after posterior scoliosis surgery with an intraoperative wake-up test using remifentanil

scientific article published in October 2008

Somatostatin infusion increases intestinal ischemia and does not improve vasoconstrictor response to norepinephrine in ovine endotoxemia

scientific article

Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation

scientific article published on 12 December 2013

T cells modulate neutrophil-dependent acute renal failure during endotoxemia: critical role for CD28.

scientific article published on 2 February 2005

Temporary right heart support with percutaneous jugular access

scientific article published in February 2006

Terlipressin dose response in healthy and endotoxemic sheep: impact on cardiopulmonary performance and global oxygen transport

scientific article published on 30 November 2002

Terlipressin for haemodynamic support in septic patients: a double-edged sword?

scientific article published in October 2002

Terlipressin for haemodynamic support in septic shock: less may be more

scientific article published on 10 July 2006

The European Working Time Directive: effect on education and clinical care

scientific article published on December 2007

The New World Health Organization Recommendations on Perioperative Administration of Oxygen to Prevent Surgical Site Infections: A Dangerous Reductionist Approach?

scientific article published on 4 July 2017

The addition of voice prompts to audiovisual feedback and debriefing does not modify CPR quality or outcomes in out of hospital cardiac arrest – A prospective, randomized trial ⬇️

scientific article published on December 13, 2010

The anaesthetist makes a difference: the bottom line matters! ⬇️

scientific article published on April 1, 2011

The effect of high thoracic epidural anesthesia on systolic and diastolic left ventricular function in patients with coronary artery disease

scientific article published in June 2005

The effects of S+-ketamine and racemic ketamine on uterine blood flow in chronically instrumented pregnant sheep

scientific article published in February 2004

The quality of epidural anesthesia is crucial in the assessment of perioperative outcome

scientific article published in July 2003

The use of concomitant antiplatelet drugs during neuraxial anethesia is contraindicated in Germany

scientific article published in November 2003

Therapeutic administration of thoracic epidural anesthesia reduces cardiopulmonary deterioration in ovine pulmonary embolism

scientific article published in November 2007

Thoracic epidural anesthesia: more than just anesthesia/analgesia

scientific article published in September 2003

Training children in cardiopulmonary resuscitation worldwide

scientific article published on 01 June 2015

Urinary TIMP-2 and IGFBP7 as early biomarkers of acute kidney injury and renal recovery following cardiac surgery

scientific article

Urinary hyaluronic acid as an early predictor of acute kidney injury after cardiac surgery

scientific article published on 01 August 2014

Validation of cell-cycle arrest biomarkers for acute kidney injury after pediatric cardiac surgery

scientific article

Xenon improves recovery from myocardial stunning in chronically instrumented dogs

scientific article

[Anesthesiologists teach teachers, teachers train students, students are lifesavers!]

scientific article published on 01 July 2014

[Definitions and recommendations are called for]

scientific article published on 01 March 2008

[More than just a "PEEP-Show"]

scientific article published on 01 July 2007

[Multimodal treatment concepts on the rise]

scientific article published on 20 January 2010

[Muscle relaxants. New findings in a timeless theme]

scientific article published on 13 May 2009

[Neurologic intensive medicine: How can secondary brain injuries be prevented?]

scientific article published on 28 October 2008

[Patient safety -- mission for the future: Anesthesia -- but sure!]

scientific article published on 01 July 2014

[Postoperative acute pain therapy--from acute pain service to acute pain program]

scientific article published on 01 January 2007

[Regional anesthesia for postoperative pain control]

scientific article published on 01 January 2007

[The cardiac risk patient: introduction and epidemiology]

scientific article published on 01 May 2006

[Ultrasound in anesthesia and intensive care - indispensable in the care of critically ill patients]

scientific article published on 11 March 2011

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