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List of works by Francis V. Chisari

A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen

scholarly article

A virocidal amphipathic -helical peptide that inhibits hepatitis C virus infection in vitro

scientific article (publication date: 26 February 2008)

An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection

scientific article (publication date: 2011)

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

scientific article

Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection

scientific article

Automated generation and evaluation of specific MHC binding predictive tools: ARB matrix applications.

scientific article published on 3 May 2005

Autophagy proteins promote hepatitis C virus replication

scientific article published in November 2009

Behçet's disease

scientific article published on 01 January 1982

Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes.

scientific article

Bortezomib inhibits hepatitis B virus replication in transgenic mice

scientific article published on 30 November 2009

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

scientific article published on 6 December 2007

CD40 activation rescues antiviral CD8⁺ T cells from PD-1-mediated exhaustion.

scientific article

CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection

scientific article

Cellular Determinants of Hepatitis C Virus Assembly, Maturation, Degradation, and Secretion

scientific article (publication date: March 2008)

Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site

scientific article published on August 2001

Characterization of the peptide-binding specificity of the chimpanzee class I alleles A 0301 and A 0401 using a combinatorial peptide library

scientific article

Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs

scientific article

Cytokine-induced viral purging--role in viral pathogenesis.

scientific article

Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures

scientific article

Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope.

scientific article

DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes.

scientific article published in August 1997

Degenerate immunogenicity of an HLA-A2-restricted hepatitis B virus nucleocapsid cytotoxic T-lymphocyte epitope that is also presented by HLA-B51.

scientific article published on April 2001

Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes

scientific article

Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules

scientific article

Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection

scientific article (publication date: 19 November 2001)

Differential Biophysical Properties of Infectious Intracellular and Secreted Hepatitis C Virus Particles

scientific article (publication date: November 2006)

Differential CD4(+) and CD8(+) T-cell responsiveness in hepatitis C virus infection

scientific article

Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen

article

Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis

scientific article published in September 1996

Distinct H-2-linked regulation of T-cell responses to the pre-S and S regions of the same hepatitis B surface antigen polypeptide allows circumvention of nonresponsiveness to the S region

scientific article published on December 1985

Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells

scholarly article

Dynamics of hepatitis B virus clearance in chimpanzees

scholarly article

Elevations of Hepatic Quinone Reductase, Glutathione, and α- and μ-Class GlutathioneS-Transferase Isoforms in Mice with Chronic Hepatitis: A Compensatory Response to Injury

scientific article published on 01 July 1996

Enhanced immunogenicity of the pre-S region of hepatitis B surface antigen.

scientific article published on June 1985

Evaluation of monoclonality of cell lines from sequential dilution assays

scientific article published in December 1987

Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees

scholarly article

Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice

scientific article

Genomic analysis of the host response to hepatitis B virus infection

scientific article

Glycylprolyl-diaminopeptidase in human leukocytes: selective occurrence in T lymphocytes and influence on the total serum enzyme activity

scientific article published on 01 June 1984

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors

scientific article published on 3 April 2010

Hepatic preneoplasia in hepatitis B virus transgenic mice

scientific article

Hepatitis B small surface antigen particles are octahedral

scientific article

Hepatitis B virus immunopathology

scientific article published on January 1995

Hepatitis B virus structure and biology

scientific article published on May 1989

Hepatitis B virus transgenic mice: insights into the virus and the disease

scientific article published on October 1995

Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress

scientific article published in August 2012

Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus

scientific article (publication date: 8 April 2008)

Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

scientific article (publication date: 15 February 2005)

Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation

scientific article

Hepatitis C virus core and E2 protein expression in transgenic mice

scientific article published on March 1997

Host-virus interactions in hepatitis B virus infection.

scientific article published on 14 July 2015

Human leukocyte antigen class I-independent pathways may contribute to hepatitis B virus-induced liver disease after liver transplantation

scientific article published in September 1993

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

scientific article (publication date: March 2010)

Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro

scientific article published on 23 October 2013

Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection

scientific article

Immune effectors required for hepatitis B virus clearance

scientific article

Immune pathogenesis of hepatocellular carcinoma.

scientific article

Immune tolerance split between hepatitis B virus precore and core proteins

scientific article

Immunobiology and pathogenesis of viral hepatitis

scientific article published on January 2006

Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections

scientific article

Immunopathology of hepatitis C.

scientific article published on January 1997

Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

scientific article published on 16 April 2015

Impact of the Autophagy Machinery on Hepatitis C Virus Infection

scientific article published on August 4, 2011

In Vivo Study of the HC-TN Strain of Hepatitis C Virus Recovered from a Patient with Fulminant Hepatitis: RNA Transcripts of a Molecular Clone (pHC-TN) Are Infectious in Chimpanzees but Not in Huh7.5 Cells

scientific article (publication date: July 2007)

In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides

article

Induction in vitro of a primary human antiviral cytotoxic T cell response

scientific article published in February 1995

Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice

scientific article

Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms

scientific article

Inhibition of hepatitis B virus replication by interferon requires proteasome activity

scientific article

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I

scientific article

Interference of hepatitis C virus RNA replication by short interfering RNAs

scientific article (publication date: 18 February 2003)

Interferon modulation of cellular microRNAs as an antiviral mechanism

scientific article (publication date: 18 October 2007)

Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids

scientific article published in July 2005

Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.

scientific article

Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice.

scientific article

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

scientific article published in January 1996

Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis

scientific article (publication date: June 2011)

Lambda interferon inhibits hepatitis B and C virus replication

scientific article

Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver

scientific article published on 12 February 2014

MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

scientific article published on April 2004

Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis

scientific article

Minisatellite rearrangements are increased in liver tumours induced by transplacental aflatoxin B1 treatment of hepatitis B virus transgenic mice, but not in spontaneously arising tumours

scientific article published in April 1997

Modulation of the in vivo immune response by human plasma very low-density lipoproteins

scientific article published in June 1980

Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

scientific article published on December 1989

Native hepatitis B virions and capsids visualized by electron cryomicroscopy

scientific article

Natural killer T cell activation inhibits hepatitis B virus replication in vivo.

scientific article

Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice.

scientific article

Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte.

scientific article

Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

scientific article

Ocular reticulum cell sarcoma. Presentation as retinal detachment with demonstration of monoclonal immunoglobulin light chains on the vitreous cells.

scientific article published in August 1981

Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.

scientific article published in July 2005

Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence.

scientific article

Pathogenesis of hepatitis B virus infection

scientific article

Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease.

scientific article published in March 2006

Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host

scientific article

Pioneers of pathogenesis: past and present

scientific article published on July 23, 2011

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection.

scientific article

Platelets mediate cytotoxic T lymphocyte-induced liver damage

scientific article

Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.

scientific article

Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes

scientific article

Previously Infected Chimpanzees Are Not Consistently Protected against Reinfection or Persistent Infection after Reexposure to the Identical Hepatitis C Virus Strain

scientific article

Production of Infectious Hepatitis C Virus by Well-Differentiated, Growth-Arrested Human Hepatoma-Derived Cells

scientific article

Production of two distinct and independent hepatic immunoregulatory molecules by the perfused rat liver

scientific article published in September 1985

Protein transfer of preformed MHC-peptide complexes sensitizes target cells to T cell cytolysis

scientific article published on October 1994

Recognition of a novel naturally processed, A2 restricted, HCV-NS4 epitope triggers IFN-gamma release in absence of detectable cytopathicity

scientific article published on December 1998

Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines.

scientific article

Replication of a hepatitis C virus replicon clone in mouse cells

scientific article (publication date: 28 October 2006)

Response of Monkeys to Immunization with Cholera Toxoid, Toxin, and Vaccine: Reversion of Cholera Toxoid

scientific article published on May 1, 1972

Retroviral-mediated transfer and expression of hepatitis B e antigen in human primary skin fibroblasts and Epstein-Barr virus-transformed B lymphocytes

scientific article published on January 1989

Robust hepatitis C virus infection in vitro

scientific article

Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus

scientific article published on November 2006

Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes

scientific article

Self-assembling peptide nanotubes with antiviral activity against hepatitis C virus

scientific article

Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity

scientific article

Sigma-1 receptor regulates early steps of viral RNA replication at the onset of hepatitis C virus infection

scientific article published on 27 March 2013

Signal transduction pathways that inhibit hepatitis B virus replication

scholarly article

Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver

scientific article published on 25 April 2014

Stealth and cunning: hepatitis B and hepatitis C viruses

scientific article

Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mice

scientific article published in March 1995

The autophagy machinery is required to initiate hepatitis C virus replication

scientific article (publication date: 18 August 2009)

The cellular immune response to nucleocapsid antigens in hepatitis B virus infection

scientific article published on January 1990

The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response.

scientific article published in October 1996

The immunopathogenesis of chronic HBV induced liver disease

scientific article

The size of the viral inoculum contributes to the outcome of hepatitis B virus infection

scientific article published on 22 July 2009

To kill or to cure: options in host defense against viral infection.

scientific article published on August 1996

Toll-like receptor signaling inhibits hepatitis B virus replication in vivo.

scientific article

Transcriptional and posttranscriptional control of hepatitis B virus gene expression

scientific article

Transmission of Type B Viral Hepatitis to Chimpanzees

scientific article published on June 1, 1973

Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture

scientific article

Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection

scientific article

Unscrambling hepatitis C virus-host interactions

scientific article published in August 2005

Use of immunoglobulin light chain analysis to detect bone marrow involvement in B-cell neoplasms

article

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

scientific article

Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

scientific article

Viral cross talk: intracellular inactivation of the hepatitis B virus during an unrelated viral infection of the liver

scientific article published on May 1996

Viral immunology: challenges associated with the progression from bench to clinic

scientific article published on 01 December 2002

Viral mutations, TCR antagonism and escape from the immune response.

scientific article published on August 1995

Virion-independent transfer of replication-competent hepatitis C virus RNA between permissive cells

scientific article

Virology. Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA".

scientific article