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List of works by Markus Affolter

A HOX complex, a repressor element and a 50 bp sequence confer regional specificity to a DPP-responsive enhancer

scientific article published in July 2001

A bacterial type III secretion-based protein delivery tool for broad applications in cell biology

scientific article

A cellular process that includes asymmetric cytokinesis remodels the dorsal tracheal branches in Drosophila larvae

scientific article published in May 2015

A conserved activation element in BMP signaling during Drosophila development

scientific article published on 13 December 2009

A family of genes encoding zona pellucida (ZP) domain proteins is expressed in various epithelial tissues during Drosophila embryogenesis

scientific article published in July 2004

A genetic mosaic analysis with a repressible cell marker screen to identify genes involved in tracheal cell migration during Drosophila air sac morphogenesis

scientific article

A lexicon for homeodomain-DNA recognition

scientific article published in June 2008

A nanobody-based toolset to investigate the role of protein localization and dispersal in Drosophila

scientific article

A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo

scientific article

A simple molecular complex mediates widespread BMP-induced repression during Drosophila development.

scientific article published on August 2004

A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax

scholarly article

Absence of 11-keto reduction of cortisone and 11-ketotestosterone in the model organism zebrafish

scientific article published on 7 December 2016

Amnioserosa cell constriction but not epidermal actin cable tension autonomously drives dorsal closure

scientific article published on 17 October 2016

AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion

scientific article published on 7 May 2014

An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo

scientific article published in March 1995

Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated

scientific article published in July 1990

Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

scientific article published in 2021

Author Correction: Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

correction of a scholarly article

BMP morphogen gradients in flies

scientific article published on 24 November 2015

Balancing import and export in development.

scientific article

Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4.

scientific article published in October 1998

Blood flow changes coincide with cellular rearrangements during blood vessel pruning in zebrafish embryos

scientific article

Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex

scientific article published on 12 December 2018

Boundaries support specific long-distance interactions between enhancers and promoters in Drosophila Bithorax complex

Branching Morphogenesis: From Cells to Organs and Back ⬇️

scientific article published on October 1, 2012

Cdh5/VE-cadherin promotes endothelial cell interface elongation via cortical actin polymerization during angiogenic sprouting

scientific article published on 16 October 2014

Cell behaviors and dynamics during angiogenesis

scientific article

Cell biology. Cytonemes show their colors.

scientific article published in April 2011

Cell-cell interaction during Drosophila embryogenesis: novel mechanisms and molecules

scientific article

Cellular and molecular mechanisms involved in branching morphogenesis of the Drosophila tracheal system

scientific article

Cellular and molecular mechanisms underlying the formation of biological tubes.

scientific article published on January 2009

Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo.

scientific article

Confronting morphogen gradients: how important are they for growth?

scientific article published on 27 October 2009

Conserved regulation of the Caenorhabditis elegans labial/Hox1 gene ceh-13.

scientific article published in February 2002

Control of Dpp morphogen signalling by a secreted feedback regulator

scientific article published on 9 May 2010

Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient

scientific article published in April 2003

Correction: Blood Flow Changes Coincide with Cellular Rearrangements during Blood Vessel Pruning in Zebrafish Embryos

scientific article published on 30 January 2014

Correction: DARPins recognizing mTFP1 as novel reagents for and protein manipulations (doi:10.1242/bio.036749)

Curing and induction of the Fels 1 and Fels 2 prophages in the Ames mutagen tester strains of Salmonella typhimurium

scientific article published in August 1983

DARPins recognizing mTFP1 as novel reagents for and protein manipulations

scientific article published on 29 October 2018

DNA binding properties of the purified Antennapedia homeodomain

scientific article

DNA recognition by the brinker repressor--an extreme case of coupling between binding and folding

scientific article published on 7 July 2006

DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo.

scientific article published in July 1997

Development and Application of Functionalized Protein Binders in Multicellular Organisms

scientific article published on 19 March 2016

Development. Legs, eyes, or wings--selectors and signals make the difference

scientific article published in May 2001

Developmental role of zebrafish protease-activated receptor 1 (PAR1) in the cardio-vascular system

scientific article

Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker

scientific article

Distamycin-induced inhibition of homeodomain-DNA complexes.

scientific article published on January 1992

Distinct and redundant functions of Esama and VE-cadherin during vascular morphogenesis

scientific article

Distinct cellular mechanisms of blood vessel fusion in the zebrafish embryo

scientific article published on 10 November 2011

Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila

scientific article published in December 2005

Downstream-of-FGFR is a fibroblast growth factor-specific scaffolding protein and recruits Corkscrew upon receptor activation

scientific article published on May 2004

Dpp from the anterior stripe of cells is crucial for the growth of the Drosophila wing disc

scientific article published on 4 July 2017

Dpp signaling activity requires Pentagone to scale with tissue size in the growing Drosophila wing imaginal disc

scientific article

Dpp signaling directs cell motility and invasiveness during epithelial morphogenesis

scientific article published on 11 March 2010

Dpp spreading is required for medial but not for lateral wing disc growth

scientific article published on 9 November 2015

Dpp/BMP signaling in flies: from molecules to biology

scientific article published on 09 May 2014

Drosophila gastrulation: identification of a missing link

scientific article published on June 2004

Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels

scientific article

Effects of the protein kinase inhibitor PKC412 on gene expression and link to physiological effects in zebrafish Danio rerio eleuthero-embryos

scientific article published on 27 October 2010

Endothelial cell division in angiogenic sprouts of differing cellular architecture

scientific article

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

scientific article published in Nature Communications

Endothelial cell self-fusion during vascular pruning

scientific article (publication date: April 2015)

Enhancer blocking and transvection at the Drosophila apterous locus

scientific article

Epithelial tube morphogenesis during Drosophila tracheal development requires Piopio, a luminal ZP protein.

scientific article published on 14 September 2003

Establishment of a Developmental Compartment Requires Interactions between Three Synergistic Cis-regulatory Modules

scientific article (publication date: October 2015)

Expression of the blistered/DSRF gene is controlled by different morphogens during Drosophila trachea and wing development

scientific article published on August 2000

Fibroblast growth factor signaling affects vascular outgrowth and is required for the maintenance of blood vessel integrity

scientific article published on 4 September 2014

Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance.

scientific article published on March 2017

Fluorescent fusion protein knockout mediated by anti-GFP nanobody

scientific article published on 11 December 2011

Formation of the long range Dpp morphogen gradient

scientific article

Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization

scientific article published in January 2015

From cells to organs: new insight into organ morphogenesis

scientific article published in October 2009

GBF1 (Gartenzwerg)-dependent secretion is required for Drosophila tubulogenesis

scientific article published on January 2012

Genetic control of branching morphogenesis during Drosophila tracheal development.

scientific article

Genetic control of cell intercalation during tracheal morphogenesis in Drosophila

scientific article published in December 2004

Genomic organization of the genes coding for the six main histones of the chicken: complete sequence of the H5 gene.

scientific article published on November 1983

Homeodomain proteins

scientific article

Homeodomain proteins and the regulation of gene expression.

scientific article published on June 1990

Homeodomain proteins in development and therapy.

scientific article published on January 1994

Homeodomain proteins: an update

scientific article

Homeodomain-DNA recognition

scientific article published on July 1994

Hox proteins meet more partners

scientific article published on 01 August 1998

Hyped-up for Hox in Hyderabad. Workshop on upstream and downstream of Hox genes

scientific article published on July 2006

IV. Tools and methods for studying cell migration and cell rearrangement in tissue and organ development

scientific article published on 12 March 2014

In memoriam--Walter J. Gehring

scientific article published on 30 May 2015

In vivo analysis of the helix-turn-helix motif of the fushi tarazu homeo domain of Drosophila melanogaster

scientific article published in June 1992

In vivo analysis reveals a highly stereotypic morphogenetic pathway of vascular anastomosis

scientific article published in June 2013

In vivo imaging reveals different cellular functions for FGF and Dpp signaling in tracheal branching morphogenesis

scientific article

Isolation and sequence-specific DNA binding of the Antennapedia homeodomain

scientific article

It takes guts to make a single lumen

scientific article published on 01 August 2007

Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction

scientific article published in Nature Communications

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

scientific article published on 10 November 2017

Mapping the molecular steps of secretory-lysosome-driven tracheal tube fusion

scientific article published in June 2016

Markus Affolter. Interview

scientific article published in February 2006

Microsomal triacylglycerol transfer protein (MTP) is required to expand tracheal lumen in Drosophila in a cell-autonomous manner

scientific article published on 6 November 2012

Modeling new conceptual interpretations of development

scientific article published in October 2011

Molecular and biochemical characterization of the aaNAT1 (Dat) locus in Drosophila melanogaster: differential expression of two gene products

scientific article published in July 1998

Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis

scientific article published in November 1994

Mutagenic response of Ames strains cured of their inducible Fels 1 and Fels 2 prophages

scientific article published in February 1983

Myosin II is not required for Drosophila tracheal branch elongation and cell intercalation.

scientific article published on August 2017

NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein

scientific article

Nuclear interpretation of Dpp signaling in Drosophila

scientific article

Pentagone: patrolling BMP morphogen signaling

scientific article published in July 2011

Polychaetoid/ZO-1 is required for cell specification and rearrangement during Drosophila tracheal morphogenesis

scientific article published in June 2006

Protein binders and their applications in developmental biology

scientific article

Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry.

scientific article

Protein knockouts in living eukaryotes using deGradFP and green fluorescent protein fusion targets

scientific article published on 24 September 2013

Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution

scientific article

Purification, cloning, and characterization of a second arylalkylamine N-acetyltransferase from Drosophila melanogaster

scientific article published on 01 November 2000

Raeppli: a whole-tissue labeling tool for live imaging of Drosophila development

scientific article published on 11 December 2013

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

scientific article (publication date: 29 July 1994)

Recognition of distinct target sites by a unique Labial/Extradenticle/Homothorax complex

scientific article published in April 2005

Reflections on the use of protein binders to study protein function in developmental biology

scientific article published on 02 July 2019

Regional repression of a Drosophila POU box gene in the endoderm involves inductive interactions between germ layers.

scientific article published in April 1993

Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

scientific article published on 28 July 2020

Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex.

scientific article published in November 1999

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway

scientific journal article

Regulation of cell migration during tracheal development in Drosophila melanogaster

scientific article

Regulation of histone and beta A-globin gene expression during differentiation of chicken erythroid cells

scientific article published on October 1987

Remodelling epithelial tubes through cell rearrangements: from cells to molecules

scientific article

Renal tubule development in Drosophila: a closer look at the cellular level

scientific article

Schnurri interacts with Mad in a Dpp-dependent manner

scientific article published in May 2000

Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1.

scientific article published in June 1995

Schnurri mediates Dpp-dependent repression of brinker transcription

scientific article published in October 2000

Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix-turn-helix motif

scientific article published on December 1988

Seeing is Believing, or How GFP Changed My Approach to Science

scientific article

Segmental homologies in the coding and 3' non-coding sequences of rat liver cytochrome P-450e and P-450b cDNAs and cytochrome P-450e-like genes

scientific article published in January 1984

Self-renewal in the fly kidney

scientific article published in September 2007

Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1

scientific article

Signal-induced repression: the exception or the rule in developmental signaling?

scientific article published on July 2008

Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila

scientific article

Signaling to Cytoskeletal Dynamics during Chemotaxis

scientific article

Similarities between the homeodomain and the Hin recombinase DNA-binding domain

scientific article published on 01 March 1991

Spalt major controls the development of the notum and of wing hinge primordia of the Drosophila melanogaster wing imaginal disc.

scientific article published on 17 March 2009

Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells

scientific article published on 9 November 2017

Specificity of FGF signaling in cell migration in Drosophila

scientific article published in November 2001

Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour

scientific article published on 10 November 2018

Structural basis of BMP signaling inhibition by Noggin, a novel twelve-membered cystine knot protein.

scientific article published in January 2003

Structural basis of BMP signalling inhibition by the cystine knot protein Noggin

scientific article

Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling

scientific article

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation

scientific article (publication date: September 2007)

The Drosophila Extradenticle and Homothorax selector proteins control branchless/FGF expression in mesodermal bridge-cells

scientific article

The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development

scientific article published in April 1994

The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered.

scientific article

The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer

scientific article published on 2 April 2015

The Drosophila protein Dof is specifically required for FGF signaling

scientific article published in October 1998

The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development

scientific article

The cramped gene of Drosophila is a member of the Polycomb-group, and interacts with mus209, the gene encoding Proliferating Cell Nuclear Antigen.

scientific article published in September 1997

The evolution of cichlid fish egg-spots is linked with a cis-regulatory change

scientific article

The hypothalamic neuropeptide oxytocin is required for formation of the neurovascular interface of the pituitary

scientific article

The interaction with DNA of wild-type and mutant fushi tarazu homeodomains

scientific article

The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis.

scientific article

The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system.

scientific article published in May 1996

The role of apoptosis in shaping the tracheal system in the Drosophila embryo

scientific article published on 6 December 2009

The structure of the homeodomain and its functional implications

scientific article published on October 1990

The tip cell concept 10 years after: new players tune in for a common theme

scientific article published on 16 February 2013

The transcription factors KNIRPS and KNIRPS RELATED control cell migration and branch morphogenesis during Drosophila tracheal development.

scientific article published in December 1998

The zebrafish common cardinal veins develop by a novel mechanism: lumen ensheathment.

scientific article published on 22 May 2013

Tip-cell migration controls stalk-cell intercalation during Drosophila tracheal tube elongation

scientific article published in November 2008

Tissue remodelling through branching morphogenesis

scientific article published on December 2009

Tracheal branching morphogenesis in Drosophila: new insights into cell behaviour and organ architecture

scientific article published on 14 May 2008

Tracheal development in Drosophila melanogaster as a model system for studying the development of a branched organ

scientific article published in April 2002

Transcription unit of the chicken histone H5 gene and mapping of H5 pre-mRNA sequences

scientific article published in September 1986

Tube or not tube: remodeling epithelial tissues by branching morphogenesis

scientific article

Tubulogenesis: Src42A Goes to Great Lengths in Tube Elongation ⬇️

scientific article published on June 5, 2012

Tugging organs into place

scientific article published in November 2013

Using Nanobodies to Study Protein Function in Developing Organisms

scientific article published on 12 February 2019

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

scientific article

Vascular morphogenesis in the zebrafish embryo

scientific article

Walter Jakob Gehring (1939–2014).

scientific article published in July 2014

Walter Jakob Gehring: A master of developmental biology

scientific article

Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling

scientific article published in Nature Communications

Zona pellucida domain proteins remodel the apical compartment for localized cell shape changes.

scientific article published in January 2010

[Gene expression and its consequences in genetic diseases]

scientific article

[The diversity of hepatic p-450 cytochromes: their role in chemical carcinogenesis]

scientific article published in September 1985

cDNA clones for liver cytochrome P-450s from individual aroclor-treated rats: constitutive expression of a new P-450 gene related to phenobarbital-inducible forms

scientific article

deGradFP: A System to Knockdown GFP-Tagged Proteins.

scientific article

eIF4A goes beyond translation

scientific article published in December 2006

gammaCOP is required for apical protein secretion and epithelial morphogenesis in Drosophila melanogaster

scientific article (publication date: 2008)

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