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List of works by Pietro De Camilli

A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism

scientific article

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

scientific article

A lentiviral system for efficient knockdown of proteins in neuronal cultures [version 1; referees: 2 approved].

scientific article

A liquid phase of synapsin and lipid vesicles

scientific article published in Science

A multiple hypothesis based method for particle tracking and its extension for cell segmentation

scientific article published on January 2013

A novel multiple hypothesis based particle tracking method for clathrin mediated endocytosis analysis using fluorescence microscopy

scientific article

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

scientific article published on March 2009

A programmable DNA-origami platform for studying lipid transfer between bilayers

scientific article published on 18 July 2019

A putative role for intramolecular regulatory mechanisms in the adaptor function of amphiphysin in endocytosis

scientific article

A role for talin in presynaptic function

scientific article

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

scientific article

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

scientific article

A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis

scientific article

ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma

scientific article

Absence of Sac2/INPP5F enhances the phenotype of a Parkinson's disease mutation of synaptojanin 1

scientific article published on 18 May 2020

All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding

scientific article

Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle

scientific article published on August 2002

Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse

scientific article

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

scientific article

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

scientific article

Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding

scientific article published on 7 August 2008

Assembly of Endocytosis-Associated Proteins on Liposomes

scientific article published on January 1, 2003

BAR, F-BAR (EFC) and ENTH/ANTH domains in the regulation of membrane-cytosol interfaces and membrane curvature

scientific article published on 28 July 2006

BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments

scientific article

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

scientific article published in Nature

CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors

scientific article

Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport.

scientific article published on 8 December 2017

Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations ⬇️

scientific article published on January 7, 2013

Cell biology of the presynaptic terminal

scientific article published on January 2003

Cell- and stimulus-dependent heterogeneity of synaptic vesicle endocytic recycling mechanisms revealed by studies of dynamin 1-null neurons

scientific article

Climate change and the integrity of science

scientific article

Competition for talin results in trans-dominant inhibition of integrin activation

scientific article

Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin

scientific article

Contacts between the endoplasmic reticulum and other membranes in neurons

scientific article

Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains

scientific article (publication date: August 2003)

Control of plasma membrane lipid homeostasis by the extended synaptotagmins

scientific article published on 11 April 2016

Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits

scientific article

Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system

scientific article

Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice

scientific article

Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout mice

scientific article

Detection and manipulation of phosphoinositides

scientific article published on 13 December 2014

Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain

scientific article

Does clathrin pull the fission trigger? ⬇️

scientific article published on April 18, 2003

Dynamic instability of clathrin assembly provides proofreading control for endocytosis

scientific article published on 26 August 2019

Dynamic interaction of amphiphysin with N-WASP regulates actin assembly

scientific article

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

scientific article published on 05 March 2014

Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling

scientific article published on 17 March 2014

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes

scientific article

Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts

scientific article

Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins

scientific article

Dynamin at actin tails ⬇️

scientific article published on January 8, 2002

Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity

scientific article

Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts

scientific article published on 30 July 2013

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors

scientific article published on 17 September 2013

Dynamin, a membrane-remodelling GTPase ⬇️

scientific article published on January 11, 2012

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

scientific article published on 03 June 2022

Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice

scientific journal article

Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice

scientific journal article

Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production

scientific article

Endoplasmic Reticulum-Plasma Membrane Contact Sites

scientific article published on 23 February 2017

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P.

scientific article published on July 2016

Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling ⬇️

scientific article published on November 26, 2012

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits

scientific article

Erratum: Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

scientific article published in Nature

Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis

scientific article published on 19 January 2009

Essential function of dynamin in the invasive properties and actin architecture of v-Src induced podosomes/invadosomes

scientific article (publication date: 2013)

GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission

scientific article

INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts

scientific article

Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells

scientific article

Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking

scientific article

Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL ⬇️

scientific article published on February 28, 2012

InsP3-mediated intracellular calcium signalling is altered by expression of synaptojanin-1.

scientific article published on September 2004

JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton

scientific article published on 10 January 2022

Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy

scientific article published on 28 November 2016

Light-activated protein interaction with high spatial subcellular confinement

scientific article published on 20 February 2018

Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion

scientific journal article

Loss of Dynamin 2 GTPase function results in microcytic anaemia

scientific article published on 3 May 2017

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques

scientific article published on 29 June 2015

Mechanisms of membrane deformation

scientific article

Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers

scientific article published on 31 October 2017

Membrane fission by dynamin: what we know and what we need to know

scientific article

Membrane trafficking: dual-key strategy

scientific article

Molecular mechanisms in membrane traffic at the neuronal synapse: role of protein-lipid interactions.

scientific article published on January 2004

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

scientific article

Mutations in phosphoinositide metabolizing enzymes and human disease

scientific article

Neurotransmission and the synaptic vesicle cycle ⬇️

scientific article published on September 1, 2002

Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells

scientific article published on 11 November 2020

Optogenetic control of phosphoinositide metabolism

scientific article

Overlapping role of dynamin isoforms in synaptic vesicle endocytosis

scientific journal article

PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins

scientific article

PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling

scientific article (publication date: 25 July 2013)

Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons

scientific article

Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles

scientific journal article

Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain

scientific article

Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion

scientific article

Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles

scientific article

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain

scientific journal article

Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry

scientific article published on 15 June 2003

Phosphoinositides in cell regulation and membrane dynamics

scientific article (publication date: 12 October 2006)

Plasticity of PI4KIIIα interactions at the plasma membrane

scientific journal article

Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: insights from vesicle recycling in nerve terminals

scholarly article

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity ⬇️

scientific article published on December 10, 2012

Rare deleterious mutations of the gene EFR3A in autism spectrum disorders.

scientific article

Recognition of the F&H; motif by the Lowe syndrome protein OCRL

scientific article

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

scientific article (publication date: 7 November 2002)

Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission ⬇️

scientific article published on November 17, 2011

Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling ⬇️

scientific article published on November 9, 2011

Reduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition

scientific article (publication date: 28 August 2012)

Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses

scientific article published on 30 January 2012

Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis

scientific journal article

Regulation of postsynaptic AMPA responses by synaptojanin 1

scientific article

Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses

scientific article

Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases

scientific article

Rhabdomyolysis and paraneoplastic stiff-man syndrome with amphiphysin autoimmunity

scientific article published in February 2004

Role of dynamin, synaptojanin, and endophilin in podocyte foot processes

scientific article

SHIP164 is a chorein motif lipid transfer protein that controls endosome-Golgi membrane traffic

scientific article published on 02 May 2022

SMP-domain proteins at membrane contact sites: Structure and function

scientific article published on 10 December 2015

Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway

scientific article

Selective high-level expression of epsin 3 in gastric parietal cells, where it is localized at endocytic sites of apical canaliculi

scientific journal article

Selective saturation of slow endocytosis at a giant glutamatergic central synapse lacking dynamin 1

scholarly article

Single-molecule force spectroscopy of protein-membrane interactions

scientific article published on 30 October 2017

Spotlight on a neuronal enzyme

scientific article published in Nature

Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex

scientific article

Structural basis of membrane invagination by F-BAR domains

scientific article

Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

scientific article

Supported native plasma membranes as platforms for the reconstitution and visualization of endocytic membrane budding

scientific article published in January 2012

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane ⬇️

scientific article published on February 27, 2012

Synaptic Vesicle Clusters at Synapses: A Distinct Liquid Phase?

scientific article published on March 2017

Synaptic vesicle endocytosis

scientific article published on September 2012

Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome

scientific journal article

TTP specifically regulates the internalization of the transferrin receptor

scientific article

Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons

scientific article published on August 1999

The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton

scientific article

The ENTH domain

scientific article (publication date: 20 February 2002)

The Extended-Synaptotagmins

scientific article published on 28 March 2017

The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures

scientific article published on 19 July 2013

The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin

scientific article

The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells

scientific article

The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals

scientific journal article

The inositol 5-phosphatase INPP5K participates in the fine control of ER organization

scientific article published on 07 August 2018

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

scientific article

The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins

scientific article

The stimulatory action of amphiphysin on dynamin function is dependent on lipid bilayer curvature

scientific article published on 19 August 2004

The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway

scientific article

The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts

scientific article

The zebrafish nrc mutant reveals a role for the polyphosphoinositide phosphatase synaptojanin 1 in cone photoreceptor ribbon anchoring.

scientific article published in October 2004

Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum-plasma membrane contact sites

scientific article published on 18 March 2015

Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering

scientific article published on 22 July 2015

Tuba, a GEF for CDC42, links dynamin to actin regulatory proteins

scientific article

Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton ⬇️

scientific article (publication date: 5 December 2003)

Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling

scientific article published on July 2009

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1

scientific article

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages

scientific article

Type I phosphotidylinosotol 4-phosphate 5-kinase γ regulates osteoclasts in a bifunctional manner

scientific article

Upregulation of Parkin in endophilin mutant mice

scientific article

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

scientific article published on 09 August 2018

Yeast protein translocation complex: Isolation of two genes SEB1 and SEB2 encoding proteins homologous to the Sec61β subunit

article

Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P2 and Membrane Scission ⬇️

scientific article published on February 16, 2012

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