List of works - Gary P. Anderson

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

article

After asthma: redefining airways diseases.

scientific article published on 11 September 2017

Serum amyloid a is a biomarker of acute exacerbations of chronic obstructive pulmonary disease

scientific article

Severe asthma in adults: what are the important questions?

scientific article

GM-CSF Biology

scientific article

Serum amyloid A opposes lipoxin A₄ to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

scientific article published on 3 January 2012

Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo.

scientific article

Distinct macrophage subpopulations characterize acute infection and chronic inflammatory lung disease

scientific article published on 11 June 2012

Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice

scientific article published on 15 July 2008

Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response

scientific article published in September 2002

Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells.

scientific article published on September 2004

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

scientific article

A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD.

scientific article published on 5 September 2007

Neutralizing Granulocyte/Macrophage Colony–Stimulating Factor Inhibits Cigarette Smoke–induced Lung Inflammation

scientific article published in July 2010

Epidermal growth factor receptor signaling to Erk1/2 and STATs control the intensity of the epithelial inflammatory responses to rhinovirus infection.

scientific article

Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4

scientific article published on November 14, 2003

Effect of short-term cigarette smoke exposure on body weight, appetite and brain neuropeptide Y in mice

scientific article

Acquired somatic mutations in the molecular pathogenesis of COPD.

scientific article

Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.

scientific article

Cigarette smoke exposure reprograms the hypothalamic neuropeptide Y axis to promote weight loss.

scientific article published on 10 March 2006

Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.

scientific article

Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System.

scientific article published on 27 May 2015

COPD and squamous cell lung cancer: aberrant inflammation and immunity is the common link.

scientific article published on 25 May 2015

Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6.

scientific article published on 30 December 2009

The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?

scientific article published on September 2003

Long-term cigarette smoke exposure increases uncoupling protein expression but reduces energy intake

scientific article published on 26 June 2008

Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity

scientific journal article

Serum amyloid A promotes lung neutrophilia by increasing IL-17A levels in the mucosa and γδ T cells.

scientific article published on July 2013

Functional relevance of the IL-23-IL-17 axis in lungs in vivo

scientific article published on 01 December 2006

Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice.

scientific article published on 28 May 2010

Carbonylation caused by cigarette smoke extract is associated with defective macrophage immunity.

scientific article

Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.

scientific article published on 4 February 2011

Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice

scientific article

Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation.

scientific article

Detrimental metabolic effects of combining long-term cigarette smoke exposure and high-fat diet in mice

scientific article published on 16 October 2007

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice.

scientific article

Characterization of pathogenic human monoclonal autoantibodies against GM-CSF.

scientific article published on 25 April 2013

Unaltered TNF-alpha production by macrophages and monocytes in diet-induced obesity in the rat.

scientific article

SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling

scientific article

S100A8 chemotactic protein is abundantly increased, but only a minor contributor to LPS-induced, steroid resistant neutrophilic lung inflammation in vivo

scientific article published in January 2005

DNA vector augments inflammation in epithelial cells via EGFR-dependent regulation of TLR4 and TLR2.

scientific article

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice

scientific article published on 20 January 2012

Regulation of hypothalamic NPY by diet and smoking.

scientific article published on 17 January 2007

Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways.

scientific article published on 21 July 2013

Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease).

scientific article

Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.

scientific article published on 2 July 2016

IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo--effects of anti-inflammatory pharmacotherapy

scientific article published on 24 December 2008

Oseltamivir treatment of mice before or after mild influenza infection reduced cellular and cytokine inflammation in the lung

scientific article published on March 31, 2011

Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.

scientific article

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.

scientific article published on 10 February 2014

List of works by Gary P. Anderson

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

After asthma: redefining airways diseases.

Serum amyloid a is a biomarker of acute exacerbations of chronic obstructive pulmonary disease

Severe asthma in adults: what are the important questions?

GM-CSF Biology

Serum amyloid A opposes lipoxin A₄ to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo.

Distinct macrophage subpopulations characterize acute infection and chronic inflammatory lung disease

Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice

Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response

Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells.

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD.

Neutralizing Granulocyte/Macrophage Colony–Stimulating Factor Inhibits Cigarette Smoke–induced Lung Inflammation

Epidermal growth factor receptor signaling to Erk1/2 and STATs control the intensity of the epithelial inflammatory responses to rhinovirus infection.

Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4

Effect of short-term cigarette smoke exposure on body weight, appetite and brain neuropeptide Y in mice

Acquired somatic mutations in the molecular pathogenesis of COPD.

Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.

Cigarette smoke exposure reprograms the hypothalamic neuropeptide Y axis to promote weight loss.

Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.

Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System.

COPD and squamous cell lung cancer: aberrant inflammation and immunity is the common link.

Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6.

The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?

Long-term cigarette smoke exposure increases uncoupling protein expression but reduces energy intake

Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity

Serum amyloid A promotes lung neutrophilia by increasing IL-17A levels in the mucosa and γδ T cells.

Functional relevance of the IL-23-IL-17 axis in lungs in vivo

Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice.

Carbonylation caused by cigarette smoke extract is associated with defective macrophage immunity.

Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.

Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice

Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation.

Detrimental metabolic effects of combining long-term cigarette smoke exposure and high-fat diet in mice

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice.

Characterization of pathogenic human monoclonal autoantibodies against GM-CSF.

Unaltered TNF-alpha production by macrophages and monocytes in diet-induced obesity in the rat.

SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling

S100A8 chemotactic protein is abundantly increased, but only a minor contributor to LPS-induced, steroid resistant neutrophilic lung inflammation in vivo

DNA vector augments inflammation in epithelial cells via EGFR-dependent regulation of TLR4 and TLR2.

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice

Regulation of hypothalamic NPY by diet and smoking.

Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways.

Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease).

Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.

IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo--effects of anti-inflammatory pharmacotherapy

Oseltamivir treatment of mice before or after mild influenza infection reduced cellular and cytokine inflammation in the lung

Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.