List of works - Eric Betzig

3D imaging of Sox2 enhancer clusters in embryonic stem cells

scientific article

3D live fluorescence imaging of cellular dynamics using Bessel beam plane illumination microscopy

scientific article

4D cell biology: big data image analytics and lattice light-sheet imaging reveal dynamics of clathrin-mediated endocytosis in stem cell-derived intestinal organoids.

scientific article published on 06 September 2018

A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells

scientific article

A localized Wnt signal orients asymmetric stem cell division in vitro

scientific article published on March 2013

A plasma membrane template for macropinocytic cups

scientific article

ADVANCED IMAGING. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics

scientific article

Actin depletion initiates events leading to granule secretion at the immunological synapse

scientific article published on May 2015

Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments

scientific article published on 23 January 2017

Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes

scientific article published on 26 September 2017

Adaptive optics via pupil segmentation for high-resolution imaging in biological tissues

scientific article

Advances in the speed and resolution of light microscopy

scientific article published on December 2008

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

scientific article

Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes

scientific article published on 24 April 2013

Characterization and adaptive optical correction of aberrations during in vivo imaging in the mouse cortex

scientific article published on 21 December 2011

Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner

scientific article

Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells

scientific article published on 01 January 2020

Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution.

scientific article published on 01 January 2019

Cytoskeletal Control of Antigen-Dependent T Cell Activation

Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation

scientific article

Cytoskeletal actin patterns shape mast cell activation

Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes

scientific article

Dynamic super-resolution structured illumination imaging in the living brain

scientific article

Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells

scientific article published on 14 November 2016

Excitation strategies for optical lattice microscopy

scientific article published in April 2005

Facile and general synthesis of photoactivatable xanthene dyes

scientific article published on 26 September 2011

Fast structural responses of gap junction membrane domains to AB5 toxins

scientific article

Flagellar membrane fusion and protein exchange in trypanosomes; a new form of cell-cell communication?

scientific article

Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse

scientific article published on 31 October 2016

High-density mapping of single-molecule trajectories with photoactivated localization microscopy

scientific article

High-density three-dimensional localization microscopy across large volumes

scientific article

High-speed, low-photodamage nonlinear imaging using passive pulse splitters

scientific article

Highly photostable, reversibly photoswitchable fluorescent protein with high contrast ratio for live-cell superresolution microscopy

scientific article

Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline

scientific article published on 28 October 2015

Imaging intracellular fluorescent proteins at nanometer resolution

scientific article (publication date: 15 September 2006)

Imaging live-cell dynamics and structure at the single-molecule level

scientific article published on May 2015

In vivo Brain Imaging with Adaptive Optical Microscope

Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure.

scientific article

Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution

scientific article

Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics

scientific article

Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy

scientific article

Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions

scientific article published on 31 December 2012

Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filaments

scientific article published on 5 March 2015

Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens

scientific article published on December 2012

Nonmuscle myosin II isoforms coassemble in living cells

scientific article

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

scientific article published in April 2018

Photoactivated Localization Microscopy (PALM) of Adhesion Complexes ⬇️

scientific article published on March 1, 2013

Photoactivated localization microscopy (PALM) of adhesion complexes

scientific article published on December 2008

Pupil-segmentation-based adaptive optical microscopy with full-pupil illumination

scientific article

Pupil-segmentation-based adaptive optics for microscopy

Quantitative semi-automated analysis of morphogenesis with single-cell resolution in complex embryos

scientific article

Rapid adaptive optical recovery of optimal resolution over large volumes

scientific article

Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination

scientific article

Real-time imaging of Huntingtin aggregates diverting target search and gene transcription

scientific article published on 3 August 2016

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

scientific article

Response to Comment on "Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics".

scientific article published on 28 April 2016

Self-organization of the Escherichia coli chemotaxis network imaged with super-resolution light microscopy

scientific article published on 16 June 2009

Self-organizing actin patterns shape membrane architecture but not cell mechanics

scientific article

Single Molecules, Cells, and Super-Resolution Optics (Nobel Lecture).

scientific article published on 18 June 2015

Single-molecule discrimination of discrete perisynaptic and distributed sites of actin filament assembly within dendritic spines

scientific article

Single-molecule dynamics of enhanceosome assembly in embryonic stem cells

scientific article

Subnuclear segregation of genes and core promoter factors in myogenesis

scientific article published on 28 February 2011

Three-dimensional tracking of plus-tips by lattice light-sheet microscopy permits the quantification of microtubule growth trajectories within the mitotic apparatus

scientific article

Triggering a cell shape change by exploiting preexisting actomyosin contractions

scientific article

V-1 regulates capping protein activity in vivo

scientific article published on 10 October 2016

Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen

scientific article

Visualizing dynamic microvillar search and stabilization during ligand detection by T cells.

scientific article

Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules

scientific article

List of works by Eric Betzig

3D imaging of Sox2 enhancer clusters in embryonic stem cells

3D live fluorescence imaging of cellular dynamics using Bessel beam plane illumination microscopy

4D cell biology: big data image analytics and lattice light-sheet imaging reveal dynamics of clathrin-mediated endocytosis in stem cell-derived intestinal organoids.

A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells

A localized Wnt signal orients asymmetric stem cell division in vitro

A plasma membrane template for macropinocytic cups

ADVANCED IMAGING. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics

Actin depletion initiates events leading to granule secretion at the immunological synapse

Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments

Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes

Adaptive optics via pupil segmentation for high-resolution imaging in biological tissues

Advances in the speed and resolution of light microscopy

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes

Characterization and adaptive optical correction of aberrations during in vivo imaging in the mouse cortex

Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner

Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells

Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution.

Cytoskeletal Control of Antigen-Dependent T Cell Activation

Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation

Cytoskeletal actin patterns shape mast cell activation

Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes

Dynamic super-resolution structured illumination imaging in the living brain

Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells

Excitation strategies for optical lattice microscopy

Facile and general synthesis of photoactivatable xanthene dyes

Fast structural responses of gap junction membrane domains to AB5 toxins

Flagellar membrane fusion and protein exchange in trypanosomes; a new form of cell-cell communication?

Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse

High-density mapping of single-molecule trajectories with photoactivated localization microscopy

High-density three-dimensional localization microscopy across large volumes

High-speed, low-photodamage nonlinear imaging using passive pulse splitters

Highly photostable, reversibly photoswitchable fluorescent protein with high contrast ratio for live-cell superresolution microscopy

Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline

Imaging intracellular fluorescent proteins at nanometer resolution

Imaging live-cell dynamics and structure at the single-molecule level

In vivo Brain Imaging with Adaptive Optical Microscope

Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure.

Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution

Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics

Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy

Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions

Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filaments

Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens

Nonmuscle myosin II isoforms coassemble in living cells

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

Photoactivated Localization Microscopy (PALM) of Adhesion Complexes ⬇️

Photoactivated localization microscopy (PALM) of adhesion complexes

Pupil-segmentation-based adaptive optical microscopy with full-pupil illumination

Pupil-segmentation-based adaptive optics for microscopy

Quantitative semi-automated analysis of morphogenesis with single-cell resolution in complex embryos

Rapid adaptive optical recovery of optimal resolution over large volumes

Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination

Real-time imaging of Huntingtin aggregates diverting target search and gene transcription

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

Response to Comment on "Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics".

Self-organization of the Escherichia coli chemotaxis network imaged with super-resolution light microscopy

Self-organizing actin patterns shape membrane architecture but not cell mechanics

Single Molecules, Cells, and Super-Resolution Optics (Nobel Lecture).

Single-molecule discrimination of discrete perisynaptic and distributed sites of actin filament assembly within dendritic spines

Single-molecule dynamics of enhanceosome assembly in embryonic stem cells

Subnuclear segregation of genes and core promoter factors in myogenesis

Three-dimensional tracking of plus-tips by lattice light-sheet microscopy permits the quantification of microtubule growth trajectories within the mitotic apparatus

Triggering a cell shape change by exploiting preexisting actomyosin contractions

V-1 regulates capping protein activity in vivo

Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen

Visualizing dynamic microvillar search and stabilization during ligand detection by T cells.

Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules