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List of works by Stephen G. Young

10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins

scientific article published on January 2006

7-Amino-actinomycin D as a cytochemical probe. I. Spectral properties

scientific article published on 01 November 1975

A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation

scientific article

A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase

scientific article published on 13 June 2018

A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.

scientific article

A gene-targeted mouse model for familial hypobetalipoproteinemia. Low levels of apolipoprotein B mRNA in association with a nonsense mutation in exon 26 of the apolipoprotein B gene

scientific journal article

A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine.

scientific article published on December 1995

A minimal ingroup advantage in emotion identification confidence

scientific article published on 28 December 2016

A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet.

scientific article published in August 1998

A mouse monoclonal antibody specific for mouse apoB48 and apoB100 produced by immunizing "apoB39-only" mice with mouse apoB48

scientific article published on 01 February 2006

A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice.

scientific article published in February 1996

A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

scientific article

A public gene trap resource for mouse functional genomics

scientific article published on June 2004

A qualitative investigation of the temporal patterning of the precompetitive anxiety response.

scientific article published in November 2002

A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.

scientific article

A truncated species of apolipoprotein B, B-83, associated with hypobetalipoproteinemia.

scientific article

Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency.

scientific article

Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice.

scientific article published on 8 October 2008

Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin

scientific article

Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation ⬇️

scientific article published on January 1, 2002

Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells

scientific article published on 01 May 2020

Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs

scientific article published on March 2013

Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity

scientific journal article

Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium

scientific journal article

An ELISA for quantifying GPIHBP1 autoantibodies and making a diagnosis of the GPIHBP1 autoantibody syndrome

scientific article published on 01 October 2018

An LPL-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1.

scientific article published on 5 August 2016

An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair.

scientific article

An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin

scientific article

An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria

scientific article

An analysis of the interaction between mouse apolipoprotein B100 and apolipoprotein(a)

scientific article published on 01 September 2000

An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum.

scientific article published in November 2017

An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner

scientific article published on 31 December 2018

Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

scientific article published on 31 March 2016

Apo B100-containing lipoproteins are secreted by the heart ⬇️

scientific article published on March 15, 1998

Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression

scientific journal article

Apolipoprotein B allotypes MB19(1) and MB19(2) in subjects with coronary artery disease and hypercholesterolemia

scientific article published on 01 January 1987

Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL.

scientific article

Apoprotein B-100 production is decreased in subjects heterozygous for truncations of apoprotein B

scientific article published on 01 January 1995

Are B-type lamins essential in all mammalian cells?

scientific article published in November 2011

Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells.

scientific article

Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria

scientific article

Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase

scientific article

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

scientific article published on 13 September 2018

Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake

scientific article published on 09 November 2023

Asymptomatic homozygous hypobetalipoproteinemia associated with apolipoprotein B45.2.

scientific article published on 01 May 1994

Balancing competing motives: adaptive trade-offs are necessary to satisfy disease avoidance and interpersonal affiliation goals.

scientific article published on 2 October 2014

Behavioural alterations in male mice lacking the gene for D-aspartate oxidase.

scientific article

Being "in" with the in-crowd: the effects of social exclusion and inclusion are enhanced by the perceived essentialism of ingroups and outgroups

scientific article published on 01 August 2010

Biochemistry and pathophysiology of intravascular and intracellular lipolysis

scientific article published on March 2013

Biventricular adaptation to volume overload in mice with aortic regurgitation.

scientific article

Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice

scientific article published on June 2008

Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER.

scientific article published on 16 February 2003

Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.

scientific article

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

scientific article

Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury.

scientific article published on 5 December 2001

Calcific aortic valve stenosis in old hypercholesterolemic mice

scientific article published on 30 October 2006

Carboxyl-terminal truncation of apolipoproteinB-100 inhibits lipoprotein(a) particle formation

scientific article published on 01 August 1994

Caution! Analyze transcripts from conditional knockout alleles

scientific article published on 18 December 2008

Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency.

scientific article published in August 1998

Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report

scientific article published on 11 August 2020

Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1

scientific article

Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase

scientific article

Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling

scientific article

Compensatory increase in hepatic lipogenesis in mice with conditional intestine-specific Mttp deficiency.

scientific article

Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium

scientific article (publication date: 2012)

Conformation of apolipoprotein B-100 in the low density lipoproteins of tangier disease. Identification of localized conformational response to triglyceride content.

scientific article

Conservation of the low density lipoprotein receptor-binding domain of apoprotein B. Demonstration by a new monoclonal antibody, MB47

scientific article published on 01 March 1986

Construction of two near-kilobase resolution restriction maps of the 5’ regulatory region of the human apolipoprotein B gene by quantitative DNA fiber mapping (QDFM) ⬇️

scientific article published on January 1, 1997

Cultured macrophages transfer surplus cholesterol into adjacent cells in the absence of serum or high-density lipoproteins

scientific article published on 30 April 2020

D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice

scientific journal article

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

scientific article published on 5 October 2011

Deficiency of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Leads to Progressive Loss of Photoreceptor Function

scientific article published on May 2016

Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

scientific article

Defining the importance of phosphatidylserine synthase 2 in mice

scientific journal article

Delayed postoperative cardiac tamponade mimicking severe tricuspid valve stenosis

scientific article published on 01 June 1984

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

scientific article

Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome

scientific article published on 01 September 2018

Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects

scientific article

Do lamin B1 and lamin B2 have redundant functions?

scientific article

Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene

scientific journal article

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

scientific journal article

Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis.

scientific article

Eliminating atherogenesis in mice by switching off hepatic lipoprotein secretion

scientific article published in March 2003

Eliminating the synthesis of mature lamin A reduces disease phenotypes in mice carrying a Hutchinson-Gilford progeria syndrome allele.

scientific article

Evidence that the low frequency antigen Orriss is part of the MN blood group system

scientific article

Exercise testing: an update.

scientific article published on May 1983

Expression of carboxyl-terminally truncated forms of human apolipoprotein B in rat hepatoma cells. Evidence that the length of apolipoprotein B has a major effect on the buoyant density of the secreted lipoproteins.

scientific article published on February 1991

Expression of human apolipoprotein B100 in transgenic mice. Editing of human apolipoprotein B100 mRNA

scientific article published on 01 November 1993

Extra Rabs unsnarl a lipid traffic jam

scientific article published on 01 July 2002

Facial redness, expression, and masculinity influence perceptions of anger and health.

scientific article published on 29 December 2016

Familial defective apolipoprotein B-100: enhanced binding of monoclonal antibody MB47 to abnormal low density lipoproteins.

scientific article

Familial hypobetalipoproteinemia associated with a mutant species of apolipoprotein B (B-46)

scientific article

Familial hypobetalipoproteinemia.

scientific article

Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells.

scientific article published on July 2006

Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration ⬇️

scientific article published on May 6, 2013

Feedback Regulation of Cholesterol Uptake by the LXR–IDOL–LDLR Axis ⬇️

scientific article published on August 30, 2012

Fibroblasts lacking nuclear lamins do not have nuclear blebs or protrusions but nevertheless have frequent nuclear membrane ruptures

article published in the Proceedings of the National Academy of Sciences of the United States of America

Four new mutations in the apolipoprotein B gene causing hypobetalipoproteinemia, including two different frameshift mutations that yield truncated apolipoprotein B proteins of identical length

scientific article published on 01 March 1993

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria ⬇️

scientific article published on September 14, 2010

GPIHBP1 and Plasma Triglyceride Metabolism

scientific article published on 14 May 2016

GPIHBP1 and lipolysis: an update

scientific article

GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia.

scientific article published on 13 June 2017

GPIHBP1 autoantibody syndrome during interferon β1a treatment

scientific article published on 24 October 2018

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.

scientific article published on 6 June 2019

GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.

scientific article published on 11 November 2014

GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins

scientific article published on 14 October 2008

GPIHBP1, an endothelial cell transporter for lipoprotein lipase ⬇️

scientific article published on August 15, 2011

Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation

scientific article

Generation of transgenic mice from yeast artificial chromosome DNA that has been modified by gene targeting.

scientific article

Genetic analyses of the role of RCE1 in RAS membrane association and transformation.

scientific article published on January 2008

Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function.

scientific article

Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.

scientific article

Genetics and molecular biology

scientific article published on 01 April 1999

Glycosylphosphatidylinositol‐anchored high‐density lipoprotein‐binding protein 1 and the intravascular processing of triglyceride‐rich lipoproteins ⬇️

scientific article published on November 1, 2012

HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells.

scholarly article

HIV-protease inhibitors block the enzymatic activity of purified Ste24p.

scientific article published on 17 July 2008

Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance.

scientific article

Hematologic effects of inactivating the Ras processing enzyme Rce1.

scientific article published on 14 November 2002

Heterogeneity in the properties of mutant secreted lymphocyte antigen 6/urokinase receptor-related protein 1 (SLURP1) in Mal de Meleda

scientific journal article

Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice

scientific journal article

High-resolution imaging and quantification of plasma membrane cholesterol by NanoSIMS.

scientific article published on 6 February 2017

High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis.

scientific article

Highly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase.

scientific article published on 02 September 2009

Human CYP7A1 deficiency: progress and enigmas

scientific article

Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine.

scientific article

Identification and molecular analysis of two apoB gene mutations causing low plasma cholesterol levels

scientific article published on 01 October 1995

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure

scientific article published on 15 February 2018

Inactivating Icmt ameliorates K-RAS-induced myeloproliferative disease.

scientific article published on 23 May 2008

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin

scientific article

Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis

scientific article published on 01 October 1995

Increased progerin expression associated with unusual LMNA mutations causes severe progeroid syndromes.

scientific article

Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24

scientific article

Intravenous Injection of Apolipoprotein A-V Reconstituted High-Density Lipoprotein Decreases Hypertriglyceridemia in apoav −/− Mice and Requires Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein–Binding Protein 1 ⬇️

scientific article published on October 21, 2010

Investigating the purpose of prelamin A processing ⬇️

scientific article published on January 1, 2011

Is red the colour of danger? Testing an implicit red-danger association.

scientific article published on 4 March 2014

Isoprenylcysteine carboxyl methyltransferase deficiency in mice

scientific article

JCL Roundtable: Hypertriglyceridemia due to defects in lipoprotein lipase function

scientific article

Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.

scientific article

LINCing lamin B2 to neuronal migration: growing evidence for cell-specific roles of B-type lamins.

scientific article

LMNA missense mutations causing familial partial lipodystrophy do not lead to an accumulation of prelamin A.

scientific article published in September 2016

Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development.

scientific article published on 13 April 2016

Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation

scientific article

Lamin B1 is required for mouse development and nuclear integrity

scientific article

Limitations of electrocardiographic scoring systems for estimation of left ventricular function

scientific article published on 01 June 1983

Limited accumulation of damaged proteins in l-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice.

scientific article

Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a.

scientific article published on May 2011

Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis

scientific article published on 03 December 2018

Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling

scientific article

Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice ⬇️

scientific article published on October 15, 1998

Lipoprotein size and atherosclerosis susceptibility in Apoe(-/-) and Ldlr(-/-) mice.

scientific article

Long runs of adenines and human mutations

scientific article published on 01 February 1998

Low plasma cholesterol levels caused by a short deletion in the apolipoprotein B gene.

scientific article published in July 1988

Lowering plasma cholesterol by raising LDL receptors--revisited.

scientific article published on March 2012

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

scientific article

Macrophages release plasma membrane-derived particles rich in accessible cholesterol

scientific article published on 20 August 2018

Manipulating large insert clones for transgenesis

scientific article published on 01 January 2003

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.

scientific article published on 15 August 2016

Mere social categorization modulates identification of facial expressions of emotion.

scientific article

Metabolic adaptations to dietary fat malabsorption in chylomicron-deficient mice.

scientific article published on October 1999

Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells

scientific article

Modification of the apolipoprotein B gene in HepG2 cells by gene targeting ⬇️

scientific article published on July 1, 1992

Modulation of LMNA splicing as a strategy to treat prelamin A diseases.

scientific article published on 21 March 2016

Molecular Basis of the Interaction between Plasma Platelet-activating Factor Acetylhydrolase and Low Density Lipoprotein

scientific article published on 01 March 1999

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL.

scientific article published on 15 November 2016

Monoclonal antibody detects Ag polymorphism of apolipoprotein B

scientific article published on 01 June 1986

Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum.

scientific article

Mouse models of the laminopathies.

scientific article

Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain

scientific article

Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a)

scientific article

Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding.

scientific article published on 5 May 2017

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia

scientific article

Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1

scientific article

N-myristoyltransferase 1 is essential in early mouse development

scientific journal article

NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes

NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes

scientific article published on 15 September 2018

NanoSIMS imaging: an approach for visualizing and quantifying lipids in cells and tissues

scientific article published on 28 October 2016

Never let them see you cry: self-presentation as a moderator of the relationship between exclusion and self-esteem

scientific article published on 16 July 2013

New Lmna knock-in mice provide a molecular mechanism for the 'segmental aging' in Hutchinson-Gilford progeria syndrome

scientific article

New wrinkles in lipoprotein lipase biology.

scientific article

Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases

scientific journal article

Nuclear lamins and neurobiology

scientific article

Nuclear lamins in the brain - new insights into function and regulation.

scientific article published on 14 October 2012

On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy.

scientific article

Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins. Evidence that hepatic lipase acts as a ligand for lipoprotein uptake.

scientific article

Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL

scientific article published on 01 November 1995

PCSK9 function and physiology.

scientific article published on July 2008

Parallel expression of the MB19 genetic polymorphism in apoprotein B-100 and apoprotein B-48. Evidence that both apoproteins are products of the same gene

scientific article published on 01 March 1986

Perception and motivation in face recognition: a critical review of theories of the Cross-Race Effect

scientific article (publication date: May 2012)

Peroxidasin-mediated bromine enrichment of basement membranes

scientific article published on 22 June 2020

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

scientific article

Phenotypic analysis of seizure-prone mice lacking L-isoaspartate (D-aspartate) O-methyltransferase.

scientific article published on July 1999

Phospholipid homeostasis in phosphatidylserine synthase-2-deficient mice

scientific article published on 31 March 2006

Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases

scientific article

Predicting Avian Influenza Co-Infection with H5N1 and H9N2 in Northern Egypt.

scientific article published on 06 September 2016

Pregnancy in a young woman with Buerger's disease. A case report

scientific article published on 01 October 1983

Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness

scientific article published on 04 October 2018

Prelamin A farnesylation and progeroid syndromes

scientific article

Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver

scientific journal article

Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated.

scientific article published on October 2008

Pure anti-Doa stimulated by pregnancy

scientific article published on 01 January 1994

Quality of professional players' poker hands is perceived accurately from arm motions.

scientific article

RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs

scientific article published on 13 February 2017

Rce1 deficiency accelerates the development of K-RAS-induced myeloproliferative disease

scientific article published on 14 September 2006

Reading-frame restoration by transcriptional slippage at long stretches of adenine residues in mammalian cells.

scientific article

Reading-frame restoration with an apolipoprotein B gene frameshift mutation.

scientific article published on December 1992

Recent progress in understanding apolipoprotein B.

scientific article

Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2.

scientific article

Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice.

scientific article published on 15 December 2011

Red enhances the processing of facial expressions of anger.

scientific article published on 6 May 2013

Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.

scientific article published on 30 January 2012

Relative contributions of apolipoprotein(a) and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice

scientific article published on 01 November 1995

Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia

scientific article published on 05 September 2019

Response to Gerlic et al.

scientific article published in March 2014

Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques

scientific article published on 21 February 2011

SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion

scientific article

SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression

scientific article published on 18 December 2015

Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases.

scientific article published on 28 October 2011

Sideroblastic Anaemia and Leukaemia in Multiple Myeloma ⬇️

scientific article published on October 1, 1978

Social exclusion and female mating behavior: rejected women show strategic enhancement of short-term mating interest.

scientific article published on 22 August 2012

Social inclusion facilitates risky mating behavior in men

scientific article published on 25 April 2011

Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs

scientific article

Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues

scientific article

Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques.

scientific article

Sterol Regulatory Element Binding Protein 1a Regulates Hepatic Fatty Acid Partitioning by Activating Acetyl Coenzyme A Carboxylase 2

Stimulus Threat and Exposure Context Modulate the Effect of Mere Exposure on Approach Behaviors

scientific article

Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis

scientific article published on 17 December 2018

Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells

scientific journal article

Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice

scientific journal article

Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate ⬇️

scientific article published on May 15, 2003

Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.

scientific article

Targeting protein prenylation in progeria

scientific article

The ABCs of cholesterol efflux

scientific article published on 01 August 1999

The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules

scientific article published on 01 December 2000

The DNA sequences required for apolipoprotein B expression in the heart are distinct from those required for expression in the intestine.

scientific article published on April 1999

The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries

scientific article published on 10 April 2014

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse

scientific article

The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice

scientific article

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain.

scientific article published on 3 January 2016

The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding.

scientific article published on 8 December 2016

The arrestin domain-containing 3 protein regulates body mass and energy expenditure

scientific article

The categorization-individuation model: an integrative account of the other-race recognition deficit.

scientific article

The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma

scientific article published on 11 September 2008

The knockout mouse project

scientific article

The neural basis of contextual influences on face categorization

scientific article

The posttranslational processing of prelamin A and disease.

scientific article

Transgene insertion on mouse chromosome 6 impairs function of the uterine cervix and causes failure of parturition.

scientific article published on 20 July 2005

Transgenic mice expressing both human apolipoprotein B and human CETP have a lipoprotein cholesterol distribution similar to that of normolipidemic humans

scientific article published on 01 May 1995

Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

scientific article

Treatment with a farnesyltransferase inhibitor improves survival in mice with a Hutchinson-Gilford progeria syndrome mutation.

scientific article

Two new monoclonal antibody-based enzyme-linked assays of apolipoprotein B

scientific article published on 01 August 1986

Understanding the Roles of Nuclear A- and B-type Lamins in Brain Development ⬇️

scientific article published on March 13, 2012

Using genetically engineered mice to understand apolipoprotein-B deficiency syndromes in humans.

scientific article

Using genetically modified mice to study apolipoprotein B.

scientific article published on January 1996

Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.

scientific article

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