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List of works by

A Chromatin Reader That Acts As a Key to Lock in and Coordinate Recruitment of Transcription Factors and a Novel Polycomb Complex to Bivalent Chromatin Thus Driving Formation of Germinal Centers and B-Cell Lymphomas ⬇️

scholarly article

Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth

scientific article published on 22 December 2008

An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas ⬇️

scientific article published on 20 October 2022

Author Correction: ChromaFold predicts the 3D contact map from single-cell chromatin accessibility ⬇️

scientific article published on 15 January 2025

BAP1 Loss Results in EZH2-Dependent Transformation in Myelodysplastic Syndromes ⬇️

scholarly article

ChromaFold predicts the 3D contact map from single-cell chromatin accessibility ⬇️

scientific article published in November 2024

Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer.

scientific article

Corrigendum to “Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer” [Steroids 76 (2011) 381–392] ⬇️

scientific article published in December 2023

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL

scientific article published on 23 April 2019

EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models ⬇️

scientific article published in February 2025

EZH2 Enables the Proliferation of Germinal Center B Cells and DLBCL through a Rb-E2F1 Positive Feedback Loop Involving Repression of CDKN1A ⬇️

scholarly article

EZH2 Gain-of-Function Mutations Generate a Lymphoma-Permissive Immune Niche ⬇️

scholarly article

EZH2 and BCL6 Cooperate To Create The Germinal Center B-Cell Phenotype and Induce Lymphomas Through Formation and Repression Of Bivalent Chromatin Domains ⬇️

scholarly article

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis

scientific journal article

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop

scientific article published on 12 October 2017

EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation

scientific article published on May 2013

Enhancer of zeste homolog 2 (EZH2) inhibitors.

scientific article published on 23 February 2018

Epigenetic Mechanisms in Leukemias and Lymphomas

scientific article published on 03 February 2020

Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells

scientific article published on 26 June 2018

Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma.

scientific article published on June 2017

Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia

scientific article

Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms

scientific article published on 10 February 2022

Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture ⬇️

scientific article published on 9 December 2020

IL10 Receptor a Is a Novel Therapeutic Target That Is Epigenetically Disregulated in Low Grade Lymphomas with Plasmacytic Differentiation. ⬇️

scholarly article

Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes

Loss of BAP1 function leads to EZH2-dependent transformation

scientific article published on 5 October 2015

Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment ⬇️

scientific article published on 3 April 2024

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition

scientific article published on 31 January 2019

Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region

scientific article published on 13 September 2016

Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response

scientific article published on 01 May 2020

Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer

scientific article published in March 2011

Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy

scientific article published on 17 December 2013

Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3

scientific article

Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma

scientific article published on 2 August 2016

Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status".

scientific article published in June 2016

Retraction Note: Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy ⬇️

scientific article published on 2 November 2023

Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation

scientific article published on 11 January 2021

Synergistic antitumor effect of combined EZH2 and DOT1L inhibition in B-cell lymphoma ⬇️

scientific article published on 26 February 2025

TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

scientific article published on 02 July 2020

TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis

scientific article published on 01 October 2018

TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways

scientific article published on 13 October 2007

Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.

scientific article

Transactivation of ErbB-2 induced by tumor necrosis factor alpha promotes NF-kappaB activation and breast cancer cell proliferation.

scientific article published on 18 September 2009

Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma

scientific article published on 01 May 2022

p42/p44 MAPK-mediated Stat3Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth

scientific article

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