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List of works by Sabine Werner

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

scientific article published on September 2017

A Glutathione-Nrf2-Thioredoxin Cross-Talk Ensures Keratinocyte Survival and Efficient Wound Repair

scientific article published on 25 January 2016

A miR-34a-SIRT6 axis in the squamous cell differentiation network

scientific article published on 16 July 2013

A modeling approach to study the effect of cell polarization on keratinocyte migration

scientific article published on 11 February 2015

A naturally occurring secreted form of fibroblast growth factor (FGF) receptor 1 binds basic FGF in preference over acidic FGF ⬇️

scientific article published on August 15, 1992

A novel Nrf2-miR-29-desmocollin-2 axis regulates desmosome function in keratinocytes

scientific article published on 6 October 2014

A novel enhancer of the wound healing process: the fibroblast growth factor-binding protein

scientific article

A novel regulator of telomerase. S100A8 mediates differentiation-dependent and calcium-induced inhibition of telomerase activity in the human epidermal keratinocyte line HaCaT.

scientific article published on 29 December 2006

A novel type of glutathione peroxidase: expression and regulation during wound repair ⬇️

scientific article published on September 1, 1997

A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming

scientific article published on 09 March 2020

A role for endogenous glucocorticoids in wound repair

scientific article

ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells

scientific article

Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models

scientific article

Accelerated wound closure in mice deficient for interleukin-10.

scientific article published on January 2007

Accumulation and activation of epidermal γδ T cells in a mouse model of chronic dermatitis is not required for the inflammatory phenotype

scientific article published on 6 July 2015

Activated Nrf2 impairs liver regeneration in mice by activation of genes involved in cell-cycle control and apoptosis

scientific article published on 18 June 2014

Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease

scientific article

Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans

scientific article published on 16 March 2005

Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice

scientific article published on 06 February 2014

Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice

scientific article

Active caspase-1 is a regulator of unconventional protein secretion

scientific article

Activin A: a novel player and inflammatory marker in inflammatory bowel disease?

scientific article published on 01 October 1997

Activin a inhibits antigen-induced allergy in murine epicutaneous sensitization

scientific article published on 22 August 2013

Activin a promotes the TGF-beta-induced conversion of CD4+CD25- T cells into Foxp3+ induced regulatory T cells

scientific article

Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes

scientific article

Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response

scientific article published on 6 December 2011

Activin promotes skin carcinogenesis by attraction and reprogramming of macrophages.

scientific article published on 08 December 2016

Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds

scientific article published on 25 May 2020

Activin: an important regulator of wound repair, fibrosis, and neuroprotection

scientific article

Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin

scientific article published on 15 September 2004

Aldara activates TLR7-independent immune defence

scientific article

Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero

scientific article published on December 2012

An important role of lymphatic vessel activation in limiting acute inflammation

scientific article

Antagonism of interferon signaling by fibroblast growth factors promotes viral replication

scientific article published on 27 July 2020

Attenuation of allergic contact dermatitis through the endocannabinoid system

scientific article

Autocrine and Paracrine Regulation of Keratinocyte Proliferation through a Novel Nrf2-IL-36γ Pathway

scientific article published on 25 April 2016

Basic fibroblast growth factor is a neurotropic factor in GT1 gonadotropin-releasing hormone neuronal cell lines ⬇️

scientific article published on September 1, 1995

Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion

scientific article

Betacellulin regulates hair follicle development and hair cycle induction and enhances angiogenesis in wounded skin

scientific article published on 25 October 2007

Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology

scientific article published on 13 June 2008

CAR takes care of the injured liver

scientific article published on 4 April 2016

Cancer as an overhealing wound: an old hypothesis revisited

scientific article published on 16 July 2008

Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation.

scientific article

Cell-specific Activation of the Nrf2 Antioxidant Pathway Increases Mucosal Inflammation in Acute but Not in Chronic Colitis

scientific article published on 28 September 2016

Cell-specific overactivation of nuclear erythroid 2 p45-related factor 2-mediated gene expression in myeloid cells decreases hepatic ischemia/reperfusion injury

scientific article published on 26 April 2016

Chemical and Biological Investigations ofβ-Oligoarginines

scientific article (publication date: 2004)

Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice

scientific article

Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin

scientific article

Corrigendum to “Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo” [Free Radic. Biol. Med. 38:1458–1470; 2005]

scholarly article published in Free Radical Biology and Medicine

Creatine kinase and creatine transporter in normal, wounded, and diseased skin

scientific article (publication date: March 2002)

Cyclic tetraureas with variable flexibility--synthesis, crystal structures and properties

scientific article

Cyclic triureas--synthesis, crystal structures and properties

scientific article published on 14 February 2008

Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities ⬇️

scientific article published on January 1, 1992

Dr. Josef Steiner Cancer Research Prize 2003 to EJCB Board Member María Blasco

scientific article

Dual role of the antioxidant enzyme peroxiredoxin 6 in skin carcinogenesis

scientific article published on 10 April 2013

Dynamics and Localization of Activin A Expression in Rat Gastric Ulcers ⬇️

scientific article published on March 1, 2003

Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo

scientific article published on 28 September 2006

Enantiopure sulforaphane analogues with various substituents at the sulfinyl sulfur: asymmetric synthesis and biological activities

scientific article published on August 2009

Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy

scientific article published on 26 February 2013

Endostatin down-regulates soluble guanylate cyclase (sGC) in endothelial cells in vivo: influence of endostatin on vascular endothelial growth factor (VEGF) signaling

scientific article published in September 2005

Epigen Transgenic Mice Develop Enlarged Sebaceous Glands

Expression and potential function of beta-amyloid precursor proteins during cutaneous wound repair

scientific article

Expression of different p63 variants in healing skin wounds suggests a role of p63 in reepithelialization and muscle repair

scientific article published on January 2005

FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin

scientific article published on 19 September 2012

FGF receptors 1 and 2 control chemically induced injury and compound detoxification in regenerating livers of mice

scientific article

Fibroblast growth factor 22 and its potential role during skin development and repair

scientific journal article

Fibroblast growth factor receptor 1-IIIb is dispensable for skin morphogenesis and wound healing

scientific article published in February 2004

Fibroblast growth factor receptor signalling is crucial for liver homeostasis and regeneration

scientific article published in July 2003

Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis

scientific article

Fibroblast growth factors and neuroprotection

scientific article

Fibroblast growth factors in epithelial repair and cytoprotection

scientific article

Fibroblast growth factors: key players in epithelial morphogenesis, repair and cytoprotection

scientific article published on October 2003

Fibroblast growth factors: key players in regeneration and tissue repair

scientific article published in November 2017

Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation

scientific journal article

Fructose protects murine hepatocytes from tumor necrosis factor-induced apoptosis by modulating JNK signaling

scientific article published on 15 November 2011

Genetic activation of Nrf2 reduces cutaneous symptoms in a murine model of Netherton syndrome

scientific article published on 26 May 2020

HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers

scientific article published on 20 March 2018

Hepatitis B virus induces expression of antioxidant response element-regulated genes by activation of Nrf2.

scientific article published on 18 October 2010

Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo

scientific article published in June 2005

Humidity-regulated CLCA2 protects the epidermis from hyperosmotic stress.

scientific article

Id2 suppression of p15 counters TGF-beta-mediated growth inhibition of melanoma cells

scientific article published on 24 April 2009

Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening

scientific article

Identification of novel AP-1 target genes in fibroblasts regulated during cutaneous wound healing.

scientific article

Immunological detection of O-GlcNAc

scientific article published in January 2002

Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance

scientific journal article

In memorian. Peter Hans Hofschneider (1929-2004).

scientific article published in December 2004

Increased keratinocyte proliferation by JUN-dependent expression of PTN and SDF-1 in fibroblasts

scientific article

Injury-activated glial cells promote wound healing of the adult skin in mice

scientific article published on 16 January 2018

Integrated multi-omics reveals cellular and molecular interactions governing the invasive niche of basal cell carcinoma

scientific article published in 2022

Interaction of the NRF2 and p63 transcription factors promotes keratinocyte proliferation in the epidermis

scientific article published on 01 April 2021

Interleukin-1, inflammasomes and the skin

scientific article published on September 2010

Kdm6b and Pmepa1 as Targets of Bioelectrically and Behaviorally Induced Activin A Signaling

scientific article published on 28 July 2015

Keratinocyte Growth Factor: A Unique Player in Epithelial Repair Processes ⬇️

scientific article published on 01 June 1998

Keratinocyte growth factor: effects on keratinocytes and mechanisms of action

scientific article

Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair

scientific article

Keratinocyte-fibroblast interactions in wound healing

scientific article published on May 2007

Knockdown and knockout of β1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling

scientific article published on 21 May 2014

Laminin α5 in the keratinocyte basement membrane is required for epidermal-dermal intercommunication

scientific article published on 24 May 2016

Langerhans cells are strongly reduced in the skin of transgenic mice overexpressing follistatin in the epidermis

scientific article published in August 2005

Large induction of keratinocyte growth factor expression in the dermis during wound healing ⬇️

scientific article published on August 1, 1992

Large-Scale Quantitative Proteomics Identifies the Ubiquitin Ligase Nedd4-1 as an Essential Regulator of Liver Regeneration

scientific article published on 30 August 2017

Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury

scientific article

Long-Term Imaging of Wound Angiogenesis with Large Scale Optoacoustic Microscopy

scientific article published on 02 May 2021

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

scientific article

Low levels of glutathione are sufficient for survival of keratinocytes after UV irradiation and for healing of mouse skin wounds

scientific article published on 4 June 2016

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes

scientific article

Mast cells are dispensable for normal and activin-promoted wound healing and skin carcinogenesis

scientific article published on 13 November 2013

Mast cells are dispensable in a genetic mouse model of chronic dermatitis

scientific article

Matrix Metalloproteinases (MMPs) and Their Physiological Inhibitors (TIMPs) Are Differentially Expressed during Excisional Skin Wound Repair ⬇️

scientific article published on July 10, 1998

MicroRNA therapy for infected wounds

scientific article published on 01 October 2018

Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth

scientific journal article

Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression ⬇️

scientific article published on October 1, 1997

Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes

scientific article published on 12 December 2019

NF-κB/RelA and Nrf2 cooperate to maintain hepatocyte integrity and to prevent development of hepatocellular adenoma

scientific article published on 5 September 2015

NRF2 and microRNAs: new but awaited relations

scientific article published on 03 August 2015

Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing

scientific article

Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis

scientific article

Nrf2 is highly expressed in neutrophils, but myeloid cell-derived Nrf2 is dispensable for wound healing in mice

scientific article published on 26 October 2017

Nrf2 links epidermal barrier function with antioxidant defense

scientific article

Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound

scientific article

Nrf2--A regulator of keratinocyte redox signaling

scientific article published on 22 April 2015

Nrf2-Mediated Expansion of Pilosebaceous Cells Accelerates Cutaneous Wound Healing

scientific article published on 26 December 2018

Nrf3 promotes UV-induced keratinocyte apoptosis through suppression of cell adhesion

scientific article published on 27 February 2018

Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals

scholarly article by Sabine Werner & Eberhard Nies published 2018 in Journal of Occupational Medicine and Toxicology

On-chip analysis of respiratory viruses from nasopharyngeal samples

scientific article

Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression

scientific article

Overactivation of the nuclear factor (erythroid-derived 2)-like 2-antioxidant response element pathway in hepatocytes decreases hepatic ischemia/reperfusion injury in mice

scientific article

Overexpression of mIGF-1 in keratinocytes improves wound healing and accelerates hair follicle formation and cycling in mice

scientific article published on 02 October 2008

Oxidative stress in normal and impaired wound repair

scientific article published on 19 June 2008

Peroxiredoxin 6 in skin carcinogenesis

scientific article published on 21 May 2014

Peroxiredoxin 6 is a potent cytoprotective enzyme in the epidermis

scientific article

Peroxiredoxin 6 is required for blood vessel integrity in wounded skin

scientific article

Pivotal role for alpha1-antichymotrypsin in skin repair

scientific article published on 21 June 2011

Potentiation of fibroblast growth factor activity by synthetic heparin oligosaccharide glycodendrimers

scientific article published on August 2007

Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk

scientific journal article

Reactive oxygen species and their detoxification in healing skin wounds

scientific article published on September 2006

Reduced Expression of PDGF and PDGF Receptors During Impaired Wound Healing ⬇️

scientific article published on 01 August 1997

Regulation of NF-kappaB activity and keratinocyte differentiation by the RIP4 protein: implications for cutaneous wound repair

scientific article

Regulation of liver regeneration by growth factors and cytokines

scientific article

Regulatory T cells are required for normal and activin-promoted wound repair in mice

scientific article published on 19 February 2018

Roles of activin in tissue repair, fibrosis, and inflammatory disease

scientific article

Src is activated by the nuclear receptor peroxisome proliferator-activated receptor β/δ in ultraviolet radiation-induced skin cancer

scientific article published on January 2014

Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity

scientific article published on 16 September 2014

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation ⬇️

scientific article published on July 1, 1993

Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population

scientific article

Targeting metabolism to treat psoriasis

scientific article published on 01 May 2018

The NLRP1 Inflammasome Pathway Is Silenced in Cutaneous Squamous Cell Carcinoma

scientific article published on 07 February 2019

The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis

scientific article

The activin binding proteins follistatin and follistatin-related protein are differentially regulated in vitro and during cutaneous wound repair ⬇️

scientific article published on December 1, 2001

The bright and the dark sides of activin in wound healing and cancer

scientific article published on 18 September 2012

The chemokine receptor CCR1 is strongly up-regulated after skin injury but dispensable for wound healing

scientific article published in March 2004

The commensal skin microbiota triggers type I IFN-dependent innate repair responses in injured skin

scientific article published on 13 July 2020

The cytoprotective Nrf2 transcription factor controls insulin receptor signaling in the regenerating liver

scientific article published on 18 January 2008

The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation

scientific article

The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair

scientific article (publication date: 11 August 2005)

The healing skin wound: a novel site of action of the chemokine C10.

scientific article

The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain ⬇️

scientific article published on September 1, 1991

The mechanical fingerprint of murine excisional wounds

scientific article published on 11 October 2017

The role of chronic inflammation in cutaneous fibrosis: fibroblast growth factor receptor deficiency in keratinocytes as an example

scientific article published on December 2011

The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development

scientific article published on 15 February 2007

The roles of activin in cytoprotection and tissue repair

scientific article

The roles of receptor tyrosine kinases and their ligands in the wound repair process

scientific article published on 08 October 2012

Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues ⬇️

scientific article published on October 1, 1997

Transcriptional control of wound repair

scientific article published on January 2007

Transcriptional regulation of wound inflammation

scientific article published on 17 February 2014

Transgenic mice expressing dominant-negative activin receptor IB in forebrain neurons reveal novel functions of activin at glutamatergic synapses

scientific article published on 2 August 2006

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation

scientific article published on 7 April 2004

Tussilagonone Ameliorates Psoriatic Features in Keratinocytes and Imiquimod-Induced Psoriasis-Like Lesions in Mice via NRF2 Activation

scientific article published on 23 December 2019

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse ⬇️

scientific article published on January 1, 1992

Unexpected down-regulation of the hIK1 Ca2+-activated K+ channel by its opener 1-ethyl-2-benzimidazolinone in HaCaT keratinocytes. Inverse effects on cell growth and proliferation

scientific article (publication date: 31 January 2003)

Upregulation and activation of the Nrf-1 transcription factor in the lesioned hippocampus

scientific article

Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation

scientific article published on 12 April 2022

Wound healing studies in transgenic and knockout mice. A review

scientific article

Wound-healing studies in transgenic and knockout mice

scientific article published in October 2004

c-Met is essential for wound healing in the skin

scientific article

cDNA cloning and expression of the gene encoding murine stromelysin-2 (MMP-10) ⬇️

scientific article published on November 20, 1997

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