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List of works by John J Tentler

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.

scientific article published on October 2015

Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development.

scientific article

Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer

scientific article (publication date: 2014)

Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.

scientific article published on 05 October 2010

Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models.

scientific article published on 17 September 2013

Patient-derived tumour xenografts as models for oncology drug development

scientific article

The Insulin-like Growth Factor I Receptor/Insulin Receptor Tyrosine Kinase Inhibitor PQIP Exhibits Enhanced Antitumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models ⬇️

scientific article published on October 13, 2010

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