List of works - J.J. Patten

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

scientific article published in February 2021

A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential

scientific article published on 4 January 2024

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

scientific article published on 19 November 2020

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

scientific article published on 01 January 2021

Adipocytes are susceptible to Ebola Virus infection

scientific article published on 27 May 2022

Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis

scholarly article published in October 2024

Anti-SARS-CoV-2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID-19 therapy

scientific article published in January 2023

Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19

scientific article published in October 2022

Design of universal Ebola virus vaccine candidates via immunofocusing

scientific article published on 13 February 2024

Ebola Virus Infection of Liver Cells: Effect of Interferon Gamma on Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line

preprint

Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo

scientific article published on 20 April 2021

Identification of filovirus entry inhibitors targeting the endosomal receptor NPC1 binding site

scientific article published on 08 March 2021

Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

scientific article published on 16 September 2022

Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation

scientific article published on 23 December 2022

Inhibition of HECT E3 ligases as potential therapy for COVID-19

scientific article

Ligand-based design of peptide entry inhibitors targeting the endosomal receptor binding site of filoviruses

scientific article published in October 2022

Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer

scientific article published on 30 September 2021

N-Substituted Pyrrole-Based Heterocycles as Broad-Spectrum Filoviral Entry Inhibitors

scholarly article published on 6 August 2024

Network medicine framework for identifying drug-repurposing opportunities for COVID-19

scientific article published on 11 May 2021

List of works by J.J. Patten

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

Adipocytes are susceptible to Ebola Virus infection

Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis

Anti-SARS-CoV-2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID-19 therapy

Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19

Design of universal Ebola virus vaccine candidates via immunofocusing

Ebola Virus Infection of Liver Cells: Effect of Interferon Gamma on Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line

Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo

Identification of filovirus entry inhibitors targeting the endosomal receptor NPC1 binding site

Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation

Inhibition of HECT E3 ligases as potential therapy for COVID-19

Ligand-based design of peptide entry inhibitors targeting the endosomal receptor binding site of filoviruses

Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer

N-Substituted Pyrrole-Based Heterocycles as Broad-Spectrum Filoviral Entry Inhibitors

Network medicine framework for identifying drug-repurposing opportunities for COVID-19