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List of works by Rebecca J. Nagy

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

scientific article published on 26 March 2019

Abstract 449: Use of comprehensive cell-free circuating tumor DNA (cfDNA) analysis to identify genomic biomarkers in newly diagnosed advanced non-small cell lung cancer (NSCLC) patients

scholarly article

Abstract LB-118: Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation

scholarly article

Acquired Resistance to Poly (ADP-ribose) Polymerase Inhibitor Olaparib in BRCA2-Associated Prostate Cancer Resulting From Biallelic BRCA2 Reversion Mutations Restores Both Germline and Somatic Loss-of-Function Mutations

scientific article published on 14 February 2018

Alterations in PTEN and ESR1 promote clinical resistance to alpelisib plus aromatase inhibitors

scientific article published on 23 March 2020

Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non-Small Cell Lung Cancer

scientific article published on 02 August 2018

An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer.

scientific article

Anaplastic lymphoma kinase mutation (ALK F1174C) in small cell carcinoma of the prostate and molecular response to alectinib.

scientific article published on 20 March 2018

BRAF Mutations Classes I, II, and III in NSCLC Patients Included in the SLLIP Trial: The Need for a New Pre-Clinical Treatment Rationale

scientific article published on 17 September 2019

Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer

scientific article published on September 2016

Blood-based next-generation sequencing analysis of neuroendocrine neoplasms

scientific article published on 12 May 2020

Cell-Free DNA Profiling to Discover Mechanisms of Exceptional Response to Cabozantinib Plus Panitumumab in a Patient With Treatment Refractory Metastatic Colorectal Cancer

scientific article published on 28 August 2018

Cell-Free DNA and Circulating Tumor Cells: Comprehensive Liquid Biopsy Analysis in Advanced Breast Cancer.

scientific article published on 27 November 2017

Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA.

scientific article published on 8 March 2018

Circulating Tumor DNA Alterations in Advanced Urothelial Carcinoma and Association with Clinical Outcomes: A Pilot Study

scientific article published on 09 March 2019

Circulating Tumor DNA Profiling of Advanced Biliary Tract Cancers

scholarly article

Circulating Tumor DNA Sequencing Analysis of Gastroesophageal Adenocarcinoma

scientific article published on 19 August 2019

Circulating tumor DNA alterations in patients with metastatic castration-resistant prostate cancer

scientific article published on 08 January 2019

Clonal Evolution and the Role of Serial Liquid Biopsies in a Case of Small-Cell Lung Cancer-Transformed EGFR Mutant Non-Small-Cell Lung Cancer

scientific article published on 07 November 2017

Combined blockade of activating mutations and ER results in synthetic lethality of ER+/HER2 mutant breast cancer

scientific article published on 12 October 2018

Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer

scientific article published on 11 November 2019

Correction: An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer

scientific article published on 01 February 2019

Correction: PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors

scientific article published on 01 February 2019

Costs of Diagnostic Assessment for Lung Cancer: A Medicare Claims Analysis

scientific article

Discrimination of Germline EGFR T790M Mutations in Plasma Cell-Free DNA Allows Study of Prevalence Across 31,414 Cancer Patients.

scientific article published on 25 September 2017

EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer

scientific article published on 21 November 2018

Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer

scientific article published on 05 December 2019

Emergence of a RET V804M Gatekeeper Mutation During Treatment With Vandetanib in RET-Rearranged NSCLC

scientific article published on 01 November 2018

Feasibility of circulating tumor DNA testing in hepatocellular carcinoma

scientific article published on 01 August 2019

Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma.

scientific article published on 4 October 2017

Genomic Profiling for KRAS, NRAS, BRAF, Microsatellite Instability, and Mismatch Repair Deficiency Among Patients With Metastatic Colon Cancer

scientific article published on 06 December 2019

Genomic landscape of cell-free DNA in patients with colorectal cancer.

scientific article

Heterogeneity and Coexistence of T790M and T790 Wild-Type Resistant Subclones Drive Mixed Response to Third-Generation Epidermal Growth Factor Receptor Inhibitors in Lung Cancer

scientific article published on 16 July 2018

Identification of Incidental Germline Mutations in Patients With Advanced Solid Tumors Who Underwent Cell-Free Circulating Tumor DNA Sequencing

scientific article published on 19 October 2018

Identification of osimertinib-resistant EGFR L792 mutations by cfDNA sequencing: oncogenic activity assessment and prevalence in large cfDNA cohort

scientific article published on 11 October 2019

Identification of somatically acquired BRCA1/2 mutations by cfDNA analysis in patients with metastatic breast cancer

scientific article published on 22 June 2020

Landscape of Acquired Resistance to Osimertinib in EGFR-Mutant NSCLC and Clinical Validation of Combined EGFR and RET Inhibition with Osimertinib and BLU-667 for Acquired RET Fusion

scientific article published on 26 September 2018

MA16.08 Clinical Utility of Detecting ROS1 Genetic Alterations in Plasma

scholarly article

MA26.03 Activity of Osimertinib and the Selective RET Inhibitor BLU-667 in an EGFR-Mutant Patient with Acquired RET Rearrangement

scholarly article

MET Alterations are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer

scientific article published on 21 February 2020

Molecular Analysis of Plasma From Patients With ROS1-Positive NSCLC

scientific article published on 18 January 2019

Molecular landscape of BRAF-mutant NSCLC reveals an association between clonality and driver mutations and identifies targetable non-V600 driver mutations

scientific article published on 12 June 2020

O.02: Plasma Next Generation Sequencing of Over 5,000 Advanced Non-Small Cell Lung Cancer Patients With Clinical Correlations

scientific article

P1.03-31 BRAF Mutations: Classes I, II and III in NSCLC Patients Included in the SLLIP Trial, Targeted Treatment According to Class ⬇️

scholarly article

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors

scientific article published on 28 December 2017

Plasma HER2 (ERBB2) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal Cancer

scientific article published on 26 February 2019

Plasma T790M Result Alters Treatment Options in a Previously T790 Wild-Type EGFR-Mutant Lung Cancer

scientific article

Polyclonal RB1 mutations and acquired resistance to CDK 4/6 inhibitors in patients with metastatic breast cancer.

scientific article

Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer

scientific article published on 01 July 2018

Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine

scientific article published on 14 June 2018

Resistance to TRK inhibition mediated by convergent MAPK pathway activation

scientific article published on 12 August 2019

Safety and Efficacy of T-DM1 Plus Neratinib in Patients With Metastatic HER2-Positive Breast Cancer: NSABP Foundation Trial FB-10

scientific article published on 23 August 2019

Targeted therapies for targeted populations: Anti-EGFR treatment for EGFR amplified gastroesophageal adenocarcinoma

scientific article published on 15 February 2018

The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 21,807 Advanced Cancer Patients

scientific article published on 18 May 2018

Therapeutic outcomes in non-small cell lung cancer with BRAF mutations: a single institution, retrospective cohort study

scientific article published on 01 June 2019

Treatment with Next-Generation ALK Inhibitors Fuels Plasma ALK Mutation Diversity

scientific article published on 29 July 2019

Use of Low-Frequency Driver Mutations Detected by Cell-Free Circulating Tumor DNA to Guide Targeted Therapy in Non–Small-Cell Lung Cancer: A Multicenter Case Series

scholarly article

Validation of a Plasma-Based Comprehensive Cancer Genotyping Assay Utilizing Orthogonal Tissue- and Plasma-Based Methodologies

scientific article published on 24 April 2018

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