List of works - Khalid Matrougui

A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus

scientific article published on 04 June 2012

Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration

scientific article

Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse

scientific article published on 31 May 2015

CD4+CD25+Foxp3 regulatory T cells and vascular dysfunction in hypertension

scientific article published on October 2013

Calcium Signaling Is Dispensable for Receptor Regulation of Endothelial Barrier Function

scientific article published on 13 September 2016

Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice.

scientific article published on 17 February 2012

Chronic inhibition of epidermal growth factor receptor tyrosine kinase and extracellular signal-regulated kinases 1 and 2 (ERK1/2) augments vascular response to limb ischemia in type 2 diabetic mice.

scientific article published on 7 November 2011

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

scientific article published on March 2014

Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase

scientific article

Differential role for stromal interacting molecule 1 in the regulation of vascular function

scientific article published on 27 June 2014

Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice

scientific article published on 04 March 2008

Emerging role of G protein-coupled receptors in microvascular myogenic tone.

scientific article published on 24 May 2012

Endoplasmic Reticulum Stress and Microvascular Endothelial Dysfunction in Diabetes

scientific article

Endoplasmic reticulum stress is involved in cardiac damage and vascular endothelial dysfunction in hypertensive mice.

scientific article published on 26 April 2012

Enhanced NF-κB activity impairs vascular function through PARP-1-, SP-1-, and COX-2-dependent mechanisms in type 2 diabetes.

scientific article

Enhanced p22phox expression impairs vascular function through p38 and ERK1/2 MAP kinase-dependent mechanisms in type 2 diabetic mice.

scientific article published on 31 January 2014

Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.

scientific article published on 28 July 2016

High-fat diet induces lung remodeling in ApoE-deficient mice: an association with an increase in circulatory and lung inflammatory factors

scientific article published on 14 September 2009

Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurements

scientific article

Interleukin-10 Released by CD4 + CD25 + Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice ⬇️

scientific article published on November 1, 2011

Involvement of tumor necrosis factor-alpha in natriuretic response to systemic infusion of nitric oxide synthase inhibitor in anesthetized mice

scientific article

Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia

scientific article

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction

scientific article

Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels

scientific article

Mechanisms of myogenic tone of coronary arteriole: Role of down stream signaling of the EGFR tyrosine kinase ⬇️

scientific article published on November 8, 2010

Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose

scientific article published on 2 May 2008

Modified multipotent stromal cells with epidermal growth factor restore vasculogenesis and blood flow in ischemic hind-limb of type II diabetic mice

scientific article

Natural regulatory T cells control coronary arteriolar endothelial dysfunction in hypertensive mice

scientific article

Nuclear factor kappa B inhibition improves conductance artery function in type 2 diabetic mice

scientific article published on January 2015

Opposing roles of PARP-1 in MMP-9 and TIMP-2 expression and mast cell degranulation in dyslipidemic dilated cardiomyopathy

scientific article

Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury.

scientific article

Orai3 is an estrogen receptor α-regulated Ca²⁺ channel that promotes tumorigenesis

scientific article

Poly(ADP-ribose) polymerase 1 inhibition improves coronary arteriole function in type 2 diabetes mellitus.

scientific article published on 26 March 2012

Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress

scientific article

Protective effects of garlic and silymarin on NDEA-induced rats hepatotoxicity

scientific article published on 11 August 2009

Role of ACE/AT2R complex in the control of mesenteric resistance artery contraction induced by ACE/AT1R complex activation in response to Ang I

scientific article published on 13 December 2007

Role of advanced glycation end products with oxidative stress in resistance artery dysfunction in type 2 diabetic mice

scientific article published on 15 May 2008

Role of elevated EGFR phosphorylation in the induction of structural remodelling and altered mechanical properties of resistance artery from type 2 diabetic mice

scientific article

STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion

scientific article published on 21 March 2013

STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry

scientific article

Sodium nitrite therapy rescues ischemia-induced neovascularization and blood flow recovery in hypertension.

scientific article

Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia

scientific article

Survivin is not only a death encounter but also a survival protein for invading tumor cells

scientific article

Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content

scientific article published on 5 January 2009

Vasodilator responses to acetylcholine are not mediated by the activation of soluble guanylate cyclase or TRPV4 channels in the rat.

scientific article

List of works by Khalid Matrougui

A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus

Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration

Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse

CD4+CD25+Foxp3 regulatory T cells and vascular dysfunction in hypertension

Calcium Signaling Is Dispensable for Receptor Regulation of Endothelial Barrier Function

Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice.

Chronic inhibition of epidermal growth factor receptor tyrosine kinase and extracellular signal-regulated kinases 1 and 2 (ERK1/2) augments vascular response to limb ischemia in type 2 diabetic mice.

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase

Differential role for stromal interacting molecule 1 in the regulation of vascular function

Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice

Emerging role of G protein-coupled receptors in microvascular myogenic tone.

Endoplasmic Reticulum Stress and Microvascular Endothelial Dysfunction in Diabetes

Endoplasmic reticulum stress is involved in cardiac damage and vascular endothelial dysfunction in hypertensive mice.

Enhanced NF-κB activity impairs vascular function through PARP-1-, SP-1-, and COX-2-dependent mechanisms in type 2 diabetes.

Enhanced p22phox expression impairs vascular function through p38 and ERK1/2 MAP kinase-dependent mechanisms in type 2 diabetic mice.

Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.

High-fat diet induces lung remodeling in ApoE-deficient mice: an association with an increase in circulatory and lung inflammatory factors

Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurements

Interleukin-10 Released by CD4 + CD25 + Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice ⬇️

Involvement of tumor necrosis factor-alpha in natriuretic response to systemic infusion of nitric oxide synthase inhibitor in anesthetized mice

Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction

Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels

Mechanisms of myogenic tone of coronary arteriole: Role of down stream signaling of the EGFR tyrosine kinase ⬇️

Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose

Modified multipotent stromal cells with epidermal growth factor restore vasculogenesis and blood flow in ischemic hind-limb of type II diabetic mice

Natural regulatory T cells control coronary arteriolar endothelial dysfunction in hypertensive mice

Nuclear factor kappa B inhibition improves conductance artery function in type 2 diabetic mice

Opposing roles of PARP-1 in MMP-9 and TIMP-2 expression and mast cell degranulation in dyslipidemic dilated cardiomyopathy

Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury.

Orai3 is an estrogen receptor α-regulated Ca²⁺ channel that promotes tumorigenesis

Poly(ADP-ribose) polymerase 1 inhibition improves coronary arteriole function in type 2 diabetes mellitus.

Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress

Protective effects of garlic and silymarin on NDEA-induced rats hepatotoxicity

Role of ACE/AT2R complex in the control of mesenteric resistance artery contraction induced by ACE/AT1R complex activation in response to Ang I

Role of advanced glycation end products with oxidative stress in resistance artery dysfunction in type 2 diabetic mice

Role of elevated EGFR phosphorylation in the induction of structural remodelling and altered mechanical properties of resistance artery from type 2 diabetic mice

STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion

STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry

Sodium nitrite therapy rescues ischemia-induced neovascularization and blood flow recovery in hypertension.

Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia

Survivin is not only a death encounter but also a survival protein for invading tumor cells

Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content

Vasodilator responses to acetylcholine are not mediated by the activation of soluble guanylate cyclase or TRPV4 channels in the rat.