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List of works by Barbara Kappes

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

scientific article published on 24 May 2018

Annotating the Plasmodium genome and the enigma of the shikimate pathway

scientific article published on February 2004

Artemisinin-(Iso)quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria

scientific article published on 08 August 2019

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

scientific article published in 2019

Assembly of the eukaryotic PLP-synthase complex from Plasmodium and activation of the Pdx1 enzyme

scientific article

Back Cover: Deeper Insight into the Six‐Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products (ChemistryOpen 3/2017).

scientific article

Deeper Insight into the Six-Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products.

scientific article published on 26 April 2017

Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase

scientific article published on 17 September 2010

Efficacy of Lefamulin Against Staphylococcus aureus-Induced Bacteremia in a Neutropenic and Immunocompetent Murine Model.

scientific article published on 4 October 2017

Export of Plasmodium falciparum calcium-dependent protein kinase 1 to the parasitophorous vacuole is dependent on three N-terminal membrane anchor motifs

scientific article (publication date: November 2004)

Expression, purification and biochemical characterization of recombinant Ca-dependent protein kinase 2 of the malaria parasite Plasmodium falciparum

scientific article

Flavogenomics--a genomic and structural view of flavin-dependent proteins

scientific article

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum.

scientific article published on 15 October 2012

Hexacyclinol, a new antiproliferative metabolite of Panus rudis HKI 0254.

scientific article

Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities

scientific article published on 29 July 2015

Hybrid integration of scalable mechanical and magnetophoretic focusing for magnetic flow cytometry.

scientific article published on 12 March 2018

Identification and characterization of novel small molecules as potent inhibitors of the plasmodial calcium-dependent protein kinase 1.

scientific article published in July 2009

Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

scientific article published in 2019

Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

scientific article published in 2019

Label-free, high-throughput detection of P. falciparum infection in sphered erythrocytes with digital holographic microscopy

scientific article published on 01 June 2018

Magnetic fingerprints of rolling cells for quantitative flow cytometry in whole blood

scientific article

Microtubule inhibitors as a potential treatment for malaria

scientific article published on August 2007

Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins

scientific article published in April 2010

New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids

scientific article published on 28 April 2015

PLP-dependent enzymes as potential drug targets for protozoan diseases

scientific article published on 24 July 2011

Quantification of human complement factor H binding to asexual malaria blood stages by an enzyme-linked immunosorbent assay.

scientific article published on 12 February 2018

Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1

scientific article (publication date: 2007)

SYBR® Green I-Based Fluorescence Assay to Assess Cell Viability of Malaria Parasites for Routine Use in Compound Screening

scientific article published in January 2017

Structural and thermodynamic insights into the assembly of the heteromeric pyridoxal phosphate synthase from Plasmodium falciparum

scientific article published on 20 September 2007

Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer

scientific article published on 19 October 2018

Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.

scientific article published in June 2017

Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents

scientific article published on 21 December 2017

Synthesis of artemisinin-derived di/tri-mers and dendrimers, investigation of their activity against P. falciparum and cytomegalovirus, and insights into their mechanisms of action.

scientific article published on 23 March 2018

Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities

scientific article published on 14 November 2018

The shikimate pathway in apicomplexan parasites: implications for drug development

scientific article published on June 2013

Two independent routes of de novo vitamin B6 biosynthesis: not that different after all.

scientific article

Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission

scientific article

Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights

scientific article

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis

scientific journal article

Vitamin and cofactor biosynthesis pathways in Plasmodium and other apicomplexan parasites

scientific article published on 2 February 2007

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