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List of works by Remo Perozzo

2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections ⬇️

scientific article published on September 18, 2010

A high yield optimized method for the production of acylated ACPs enabling the analysis of enzymes involved in P. falciparum fatty acid biosynthesis

scientific article published on 6 October 2016

Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics

scientific article

Anthecularin: A Novel Sesquiterpene Lactone from Anthemis auriculata with Antiprotozoal Activity

scientific article published in October 2007

Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots

scientific article

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica

scientific article published on 14 October 2014

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

scientific article

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

scientific article published on 25 February 2008

ChemInform Abstract: Anthecularin (I): A Novel Sesquiterpene Lactone from Anthemis auriculata with Antiprotozoal Activity

scientific article published on 31 January 2008

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

scientific article published on 11 June 2015

Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation

scientific article

Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI)

scientific article

Expression, purification and biochemical characterization of recombinant Ca-dependent protein kinase 2 of the malaria parasite Plasmodium falciparum

scientific article

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum.

scientific article published on 15 October 2012

Generation of Stilbene Antimicrobials against Multiresistant Strains of Staphylococcus aureus through Biotransformation by the Enzymatic Secretome of Botrytis cinerea

scientific article published on 24 July 2020

High-level expression and purification of human thymidine kinase 1: quaternary structure, stability, and kinetics

scientific article published on 30 January 2006

In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA.

scientific article published on 5 January 2016

Inhibiting activities of the secondary metabolites of Phlomis brunneogaleata against parasitic protozoa and plasmodial enoyl-ACP Reductase, a crucial enzyme in fatty acid biosynthesis

scientific article published on August 2004

Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata.

scientific article

Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids

scientific article

Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli

scientific article published on 22 August 2007

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

scientific article

Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism

scientific article

Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities

Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology

scientific article published on 27 June 2016

Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6

scientific article published on 25 May 2020

Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target

scientific article published on 19 June 2013

Purine metabolite and energy charge analysis of Trypanosoma brucei cells in different growth phases using an optimized ion-pair RP-HPLC/UV for the quantification of adenine and guanine pools

scientific article published on 19 March 2014

RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α

scientific article published on 12 August 2020

RNA pentaloop structures as effective targets of regulators belonging to the RsmA/CsrA protein family

scientific article

Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates.

scientific article published on 8 February 2006

Single-molecule pulling simulations can discern active from inactive enzyme inhibitors

scientific article published on June 2010

Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase

scientific article published on 12 April 2002

Structure-based drug design and in vitro testing reveal new inhibitors of enoyl-acyl carrier protein reductases

scientific article published on 02 June 2019

Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives

scientific article published on 20 October 2007

Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities

scientific article

Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity

scientific article

Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo

scientific article

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.

scientific article

Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data

scientific article (publication date: 6 June 2003)

Temperature-Dependent NMR and CD Spectra ofβ-Peptides: On the Thermal Stability ofβ-Peptide Helices - Is the Folding Process ofβ-Peptides Non-cooperative?

The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum.

scientific article published on June 2005

The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery.

scientific article published on January 2012

Thermodynamics of protein-ligand interactions: history, presence, and future aspects

scientific article published in February 2004

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