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List of works by Yan Huang

A large, single-center, real-world study of clinicopathological characteristics and treatment in advanced ALK-positive non-small-cell lung cancer

scientific article

A multicenter, retrospective epidemiologic survey of the clinical features and management of bone metastatic disease in China

scientific article published on 25 April 2016

A randomized, controlled, multicenter clinical trial comparing pemetrexed/cisplatin and gemcitabine/cisplatin as first-line treatment for advanced nonsquamous non-small cell lung cancer ⬇️

scientific article published on October 1, 2012

A retrospective analysis of the clinicopathological and molecular characteristics of pulmonary blastoma

scientific article

Advanced Lung Cancer Inflammation Index, a New Prognostic Score, Predicts Outcome in Patients With Small-Cell Lung Cancer

scientific article published on 26 March 2015

An investigation of symptom burden and quality of life in Chinese chemo-naïve advanced lung cancer patients by using the Instrument-Cloud QOL System

scientific article published on 7 February 2014

Anti-epidermal growth factor receptor monoclonal antibody plus palliative chemotherapy as a first-line treatment for recurrent or metastatic nasopharyngeal carcinoma

scientific article published on 19 January 2020

Autoimmune Diseases and Lung Cancer: A Mendelian Randomization Study

scientific article published on 01 August 2019

CT-Based Radiomics to Differentiate Pelvic Rhabdomyosarcoma From Yolk Sac Tumors in Children

scientific article published on 24 November 2020

Camrelizumab (SHR-1210) alone or in combination with gemcitabine plus cisplatin for nasopharyngeal carcinoma: results from two single-arm, phase 1 trials

scientific article published on 10 September 2018

Cause-specific death assessment of patients with stage I small-cell lung cancer: a competing risk analysis

scientific article published on 26 June 2019

Changes of bone resorption marker (NTX) in chemotherapy plus zoledronic acid versus chemotherapy alone for nasopharyngeal cancer patients with bone metastases ⬇️

scientific article published on January 20, 2011

Chemotherapy Near the End of Life for Chinese Patients with Solid Malignancies

scientific article

Clinical analysis of 50 Eastern Asian patients with primary pulmonary large-cell neuroendocrine carcinoma

scientific article published on 26 May 2015

Clinical pharmacokinetics and drug exposure-toxicity correlation study of docetaxel based chemotherapy in Chinese head and neck cancer patients

scientific article published on 01 March 2020

Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment ⬇️

scientific article published on 03 July 2013

Co-expression of PD-1 and PD-L1 predicts poor outcome in nasopharyngeal carcinoma

scientific article

Combinatorial assessment of ctDNA release and mutational burden predicts anti-PD(L)1 therapy outcome in nonsmall-cell lung cancer

scientific article published on 01 January 2020

Comparison of First-Line Treatments for Patients With Extensive-Stage Small Cell Lung Cancer: A Systematic Review and Network Meta-analysis

scientific article published on 01 October 2020

Comparison of the Prognostic Value of Systemic Inflammation Response Markers in Small Cell Lung Cancer Patients.

scientific article

Concomitant Genetic Alterations With Response to Treatment and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With EGFR-Mutant Advanced Non-Small Cell Lung Cancer

scientific article published on 29 March 2018

Correction to: Pharmacokinetic and Pharmacodynamic Analyses of 5-Fluorouracil in East-Asian Patients with Nasopharyngeal Carcinoma

scientific article published on 26 December 2017

Development and validation of a nomogram for predicting the survival of patients with non-metastatic nasopharyngeal carcinoma after curative treatment

scientific article

Dual blockade of EGFR and VEGFR pathways: Results from a pilot study evaluating apatinib plus gefitinib as a first-line treatment for advanced EGFR-mutant non-small cell lung cancer

scientific article published on 04 June 2020

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

scientific article

EGFR T790M relative mutation purity predicts osimertinib treatment efficacy in non-small cell lung cancer patients

scientific article published on 17 February 2020

EGFR mutation genotypes affect efficacy and resistance mechanisms of osimertinib in T790M-positive NSCLC patients

scientific article published on 01 June 2020

Education and lung cancer: a Mendelian randomization study

scientific article published on 01 June 2019

Effects of an oral allosteric AKT inhibitor (MK-2206) on human nasopharyngeal cancer in vitro and in vivo

scientific article

Efficacy and Tolerability of Erlotinib 100 mg/d vs. Gefitinib 250 mg/d in EGFR-Mutated Advanced Non-small Cell Lung Cancer (E100VG250): An Open-Label, Randomized, Phase 2 Study

scientific article published on 10 November 2020

Efficacy of Addition of Antiangiogenic Agents to Taxanes-Containing Chemotherapy in Advanced Nonsmall-Cell Lung Cancer: A Meta-Analysis and Systemic Review

scientific article (publication date: August 2015)

Efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors for Chinese patients with squamous cell carcinoma of lung harboring EGFR mutation

scientific article published on October 2013

Efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in nasopharyngeal carcinoma in vitro and in vivo

scientific article published on 03 May 2018

Erlotinib plus capecitabine as first-line treatment for older Chinese patients with advanced adenocarcinoma of the lung (C-TONG0807): an open-label, single arm, multicenter phase II study

scientific article

Erratum: Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer

scientific article

Establishment and application of a predictive model for gefitinib-induced severe rash based on pharmacometabolomic profiling and polymorphisms of transporters in non-small cell lung cancer

scientific article published on 19 November 2020

Expression of RRM1 and its association with resistancy to gemcitabine-based chemotherapy in advanced nasopharyngeal carcinoma ⬇️

scientific article published on 06 June 2012

Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer

scientific article published on 29 January 2016

Fosaprepitant versus aprepitant in the prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based chemotherapy: a multicenter, randomized, double-blind, double-simulated, positive-controlled phase III trial

scientific article published on 01 March 2020

Gemcitabine plus cisplatin versus fluorouracil plus cisplatin in recurrent or metastatic nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial.

scientific article

Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-based Subtypes

scientific article published on 29 August 2017

Hepatitis B virus reactivation in cancer patients with positive Hepatitis B surface antigen undergoing PD-1 inhibition

scientific article published on 21 November 2019

Immune-checkpoint inhibitor plus chemotherapy versus conventional chemotherapy for first-line treatment in advanced non-small cell lung carcinoma: a systematic review and meta-analysis

scientific article published on 22 December 2018

Immune-related pneumonitis associated with immune checkpoint inhibitors in lung cancer: a network meta-analysis

scientific article published on 01 August 2020

Impact of gefitinib in early stage treatment on circulating cytokines and lymphocytes for patients with advanced non-small cell lung cancer

scientific article published on 21 February 2017

Impact of prior cancer on outcomes in nasopharyngeal carcinoma

scientific article published on 01 July 2019

Inhibiting eEF-2 kinase-mediated autophagy enhanced the cytocidal effect of AKT inhibitor on human nasopharyngeal carcinoma

scholarly article by Yuan-Yuan Zhao et al published 2018 in Drug Design, Development and Therapy

Intratumor heterogeneity comparison among different subtypes of non-small-cell lung cancer through multi-region tissue and matched ctDNA sequencing

scholarly article by Yaxiong Zhang et al published 9 January 2019 in Molecular Cancer

Lactate dehydrogenase and creatine kinase as poor prognostic factors in lung cancer: A retrospective observational study

scientific article

Low Prognostic Nutritional Index Correlates with Worse Survival in Patients with Advanced NSCLC following EGFR-TKIs

scientific article published on 19 January 2016

Mendelian randomization study showed no causality between metformin use and lung cancer risk

scientific article published on 19 October 2019

Modification of the tumor response threshold in patients of advanced non-small cell lung cancer treated with chemotherapy plus targeted agents: a pooled study from five clinical trials in one institution

scientific article published on 01 June 2019

Multi-targeted antiangiogenic tyrosine kinase inhibitors in advanced non-small cell lung cancer: meta-analyses of 20 randomized controlled trials and subgroup analyses

scientific article

Multi-targeted tyrosine kinase inhibitors as third-line regimen in advanced non-small cell lung cancer: a network meta-analysis

scientific article published on 01 September 2019

Multiple oncogenic mutations related to targeted therapy in nasopharyngeal carcinoma

scientific article

National survey of the medical treatment status for non-small cell lung cancer (NSCLC) in China

scientific article

Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations

scientific article published in 2014

Neurokinin-1 Receptor Antagonist-Based Triple Regimens in Preventing Chemotherapy-Induced Nausea and Vomiting: A Network Meta-Analysis

scientific article published on 30 October 2016

Nomogram to Predict Cause-Specific Mortality in Patients With Surgically Resected Stage I Non-Small-Cell Lung Cancer: A Competing Risk Analysis.

scientific article published on 28 October 2017

Olanzapine-Based Triple Regimens Versus Neurokinin-1 Receptor Antagonist-Based Triple Regimens in Preventing Chemotherapy-Induced Nausea and Vomiting Associated with Highly Emetogenic Chemotherapy: A Network Meta-Analysis.

scientific article published on 12 January 2018

Open-label, single-arm phase II study of pemetrexed in the treatment of patients with recurrent or metastatic nasopharyngeal carcinoma who have had prior platinum-based chemotherapy ⬇️

scientific article published on August 19, 2012

Optimal prophylaxis of chemotherapy-induced nausea and vomiting for moderately emetogenic chemotherapy: a meta-analysis

scientific article published on 18 July 2018

Optimal tumor shrinkage predicts long-term outcome in advanced nonsmall cell lung cancer (NSCLC) treated with target therapy: Result from 3 clinical trials of advanced NSCLC by 1 institution

scientific article published on August 2016

Optimized selection of three major EGFR-TKIs in advanced EGFR-positive non-small cell lung cancer: a network meta-analysis

scientific article

PD-L1 is remarkably over-expressed in EBV-associated pulmonary lymphoepithelioma-like carcinoma and related to poor disease-free survival

scientific article published on 24 August 2015

PI3K-AKT-mTOR pathway alterations in advanced NSCLC patients after progression on EGFR-TKI and clinical response to EGFR-TKI plus everolimus combination therapy

scientific article published on 01 August 2020

Pemetrexed/carboplatin plus gefitinib as a first-line treatment for EGFR-mutant advanced nonsmall cell lung cancer: a Bayesian network meta-analysis

scientific article published on 30 December 2019

Personalized Estimate of Chemotherapy-Induced Nausea and Vomiting: Development and External Validation of a Nomogram in Cancer Patients Receiving Highly/Moderately Emetogenic Chemotherapy.

scientific article

Pharmacokinetic and Pharmacodynamic Analyses of 5-Fluorouracil in East-Asian Patients with Nasopharyngeal Carcinoma

scientific article published in October 2016

Phase I dose-escalation study of aflibercept plus docetaxel in nasopharyngeal carcinoma and other solid tumors

scientific article published on December 2014

Phase I/II dose-finding study of nanoparticle albumin-bound paclitaxel (nab®-Paclitaxel) plus Cisplatin as Treatment for Metastatic Nasopharyngeal Carcinoma

scientific article

Polymorphisms of NF-κB pathway genes influence adverse drug reactions of gefitinib in NSCLC patients

scientific article published on 30 October 2019

Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin’s lymphoma

scholarly article

Predictive Value of Intratumoral Microvascular Density in Patients with Advanced Non-small Cell Lung Cancer Receiving Chemotherapy Plus Bevacizumab ⬇️

scientific article published on January 1, 2012

Pretreatment Albumin/Globulin Ratio Predicts the Prognosis for Small-Cell Lung Cancer

scientific article published on March 2016

Prevalence of Burnout and Career Satisfaction Among Oncologists in China: A National Survey

scientific article published on 19 December 2018

Prognostic significance of the combined score of endothelial expression of nucleolin and CD31 in surgically resected non-small cell lung cancer

scientific article

Prognostic significance of thymidylate synthase in postoperative non-small cell lung cancer patients

scientific article

Prognostic value of serum high-density lipoprotein cholesterol elevation in nonsmall cell lung cancer patients receiving radical surgery

scientific article published on 05 June 2020

Publisher Correction: Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC.

scientific article

QoL analyses from INFORM study, a phase III study of gefitinib versus placebo as maintenance therapy in advanced NSCLC.

scientific article published on 3 July 2015

Ratio of C-Reactive Protein/Albumin is An Inflammatory Prognostic Score for Predicting Overall Survival of Patients with Small-cell Lung Cancer

scientific article published on 18 June 2015

Retraction Note: p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells

scientific article published in 2023

Risk of second primary malignancy after non-small cell lung cancer: a competing risk nomogram based on the SEER database

scientific article published on 01 September 2019

Risk of treatment-related deaths with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a meta-analysis of 41 randomized controlled trials

scientific article

SPARC expression and prognostic value in non-small cell lung cancer ⬇️

scientific article published on October 10, 2012

Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC).

scientific article

Serum proteomic study on EGFR-TKIs target treatment for patients with NSCLC.

scientific article

Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC.

scientific article

Suicide among cancer patients: adolescents and young adult (AYA) versus all-age patients

scientific article published on 01 November 2019

The ACTIVE study protocol: apatinib or placebo plus gefitinib as first-line treatment for patients with EGFR-mutant advanced non-small cell lung cancer (CTONG1706)

scientific article published on 07 November 2019

The Difference of Clinical Characteristics Between Patients With Exon 19 Deletion and Those With L858R Mutation in Nonsmall Cell Lung Cancer

scientific article

The Dissociation of Gefitinib Trough Concentration and Clinical Outcome in NSCLC Patients with EGFR Sensitive Mutations.

scientific article published on 31 July 2015

The Efficacy and Toxicity of Lobaplatin-contained Chemotherapy in Extensive-stage Small-cell Lung Cancer

scientific article published on 05 June 2018

The Efficacy of Combining EGFR Monoclonal Antibody With Chemotherapy for Patients With Advanced Nonsmall Cell Lung Cancer: A Meta-Analysis From 9 Randomized Controlled Trials

scientific article

The comparison of EGFR-TKI failure modes and subsequent management between exon 19 deletion and exon 21 L858R mutation in advanced non-small-cell lung cancer

scientific article published on 2 July 2017

The correlations of tumor mutational burden among single-region tissue, multi-region tissues and blood in non-small cell lung cancer

scientific article published on 03 April 2019

The efficacy and toxicity of afatinib in advanced EGFR-positive non-small-cell lung cancer patients after failure of first-generation tyrosine kinase inhibitors: a systematic review and meta-analysis

scientific article

The efficacy of combining antiangiogenic agents with chemotherapy for patients with advanced non-small cell lung cancer who failed first-line chemotherapy: a systematic review and meta-analysis

scientific article published on 2 June 2015

The efficacy of first-line chemotherapy in recurrent or metastatic nasopharyngeal carcinoma: a systematic review and meta-analysis

scientific article published on 01 June 2018

The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma

scientific article published on 25 February 2016

The good pain management (GPM) ward program in China and its impact on Chinese cancer patients: the SYSUCC experience

scientific article

The impact of both platinum-based chemotherapy and EGFR-TKIs on overall survival of patients with advanced non-small cell lung cancer ⬇️

scientific article published on 02 July 2013

The impact of tumor size change after target therapy on survival: analysis of patients enrolled onto three clinical trials of advanced NSCLC from one institution ⬇️

scientific article published on November 15, 2012

The perception gap of chemotherapy-induced adverse events between doctors and cancer patients: an observational study in China

scientific article published on 29 July 2020

The prognostic nutritional index (PNI) predicts overall survival of small-cell lung cancer patients

scientific article published on 20 December 2014

Therapeutic Efficacy Comparison of 5 Major EGFR-TKIs in Advanced EGFR-positive Non-Small-cell Lung Cancer: A Network Meta-analysis Based on Head-to-Head Trials

scientific article published on 27 October 2016

Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation

scientific article

Upregulation of PD-L1 by EML4-ALK fusion protein mediates the immune escape in ALK positive NSCLC: Implication for optional anti-PD-1/PD-L1 immune therapy for ALK-TKIs sensitive and resistant NSCLC patients

scientific article published on 21 December 2015

p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells.

scientific article published on 7 June 2018

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