List of works - Norihiko Ohbayashi

A Varp-Binding Protein, RACK1, Regulates Dendrite Outgrowth through Stabilization of Varp Protein in Mouse Melanocytes

scientific article published on 8 April 2016

ACAP3 regulates neurite outgrowth through its GAP activity specific to Arf6 in mouse hippocampal neurons.

scientific article published on 21 June 2016

Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis

scientific article published on 27 October 2015

An RNA biding protein, Y14 interacts with and modulates STAT3 activation

scientific article published on 27 May 2008

Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration.

scientific article published on 12 September 2017

Atmospheric scanning electron microscope system with an open sample chamber: configuration and applications

scientific article

C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia

scientific article

Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.

scientific article published on 12 January 2010

Correction: The GTPase Rab37 Participates in the Control of Insulin Exocytosis.

scientific article

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis

scientific journal article

Fgf18 is required for embryonic lung alveolar development

scientific journal article

Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2.

scientific article published on 3 April 2010

Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes

scientific journal article

Genome-wide investigation of the Rab binding activity of RUN domains: development of a novel tool that specifically traps GTP-Rab35.

scientific article published on 7 July 2011

Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

scientific article

LIF- and IL-6-induced acetylation of STAT3 at Lys-685 through PI3K/Akt activation

scientific article

Measurement of Rab35 activity with the GTP-Rab35 trapper RBD35.

scientific article

Melanoregulin regulates retrograde melanosome transport through interaction with the RILP·p150Glued complex in melanocytes ⬇️

scientific article published on January 24, 2012

Pathological functions of the small GTPase Arf6 in cancer progression: Tumor angiogenesis and metastasis

scientific article published on 24 February 2016

Phosphorylation of threonine-265 in Zipper-interacting protein kinase plays an important role in its activity and is induced by IL-6 family cytokines.

scientific article published on 9 November 2005

Physical and functional interactions between ZIP kinase and UbcH5

scientific article

Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation.

scientific article published on 19 April 2018

RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes

scientific journal article

Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP.

scientific article published on 4 February 2015

Rab32 subfamily small GTPases: pleiotropic Rabs in endosomal trafficking

scientific article

Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth

scientific article published on August 2014

Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes

scientific article published on 6 February 2015

Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis

scientific article published on 2 April 2014

Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP2-producing enzyme PIP5K1A

scientific article published on 25 August 2017

Regulation of mammalian tooth cusp patterning by ectodin

scientific journal article

Role of Rab family GTPases and their effectors in melanosomal logistics.

scientific article published on 09 February 2012

STAP-2 negatively regulates both canonical and noncanonical NF-kappaB activation induced by Epstein-Barr virus-derived latent membrane protein 1.

scientific article

STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells

scientific article published on 14 May 2007

Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase.

scientific article

Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.

scientific article

Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-beta signaling.

scientific article

Syntaxin-3 is required for melanosomal localization of Tyrp1 in melanocytes

scientific journal article

TBC1D24 regulates recycling of clathrin-independent cargo proteins mediated by tubular recycling endosomes

scientific article published on 28 May 2020

The GTPase Rab37 Participates in the Control of Insulin Exocytosis

scientific article

The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targetinG tag.

scientific article

The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction.

scientific article

The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses

scientific article published on September 2017

The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes.

scientific article published on 27 June 2012

The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes

scientific journal article

The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking

scientific journal article

The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing.

scientific article published on 21 April 2017

Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking

scientific article published in 2022

Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes

scientific journal article

List of works by Norihiko Ohbayashi

A Varp-Binding Protein, RACK1, Regulates Dendrite Outgrowth through Stabilization of Varp Protein in Mouse Melanocytes

ACAP3 regulates neurite outgrowth through its GAP activity specific to Arf6 in mouse hippocampal neurons.

Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis

An RNA biding protein, Y14 interacts with and modulates STAT3 activation

Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration.

Atmospheric scanning electron microscope system with an open sample chamber: configuration and applications

C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia

Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.

Correction: The GTPase Rab37 Participates in the Control of Insulin Exocytosis.

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis

Fgf18 is required for embryonic lung alveolar development

Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2.

Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes

Genome-wide investigation of the Rab binding activity of RUN domains: development of a novel tool that specifically traps GTP-Rab35.

Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

LIF- and IL-6-induced acetylation of STAT3 at Lys-685 through PI3K/Akt activation

Measurement of Rab35 activity with the GTP-Rab35 trapper RBD35.

Melanoregulin regulates retrograde melanosome transport through interaction with the RILP·p150Glued complex in melanocytes ⬇️

Pathological functions of the small GTPase Arf6 in cancer progression: Tumor angiogenesis and metastasis

Phosphorylation of threonine-265 in Zipper-interacting protein kinase plays an important role in its activity and is induced by IL-6 family cytokines.

Physical and functional interactions between ZIP kinase and UbcH5

Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation.

RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes

Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP.

Rab32 subfamily small GTPases: pleiotropic Rabs in endosomal trafficking

Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth

Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes

Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis

Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP2-producing enzyme PIP5K1A

Regulation of mammalian tooth cusp patterning by ectodin

Role of Rab family GTPases and their effectors in melanosomal logistics.

STAP-2 negatively regulates both canonical and noncanonical NF-kappaB activation induced by Epstein-Barr virus-derived latent membrane protein 1.

STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells

Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase.

Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.

Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-beta signaling.

Syntaxin-3 is required for melanosomal localization of Tyrp1 in melanocytes

TBC1D24 regulates recycling of clathrin-independent cargo proteins mediated by tubular recycling endosomes

The GTPase Rab37 Participates in the Control of Insulin Exocytosis

The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targetinG tag.

The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction.

The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses

The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes.

The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes

The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking

The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing.

Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking

Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes