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List of works by Christopher J. Wheeler

A Simple Three-dimensional Hydrogel Platform Enables Ex Vivo Cell Culture of Patient and PDX Tumors for Assaying Their Response to Clinically Relevant Therapies

scientific article published on 12 February 2019

A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma

scientific article published on 10 March 2020

ATIM-18. A PHASE I TRIAL OF VACCINATION WITH AUTOLOGOUS DENDRITIC CELLS PULSED WITH LYSATE DERIVED FROM AN ALLOGENEIC GLIOBLASTOMA STEMLIKE CELL LINE FOR PATIENTS WITH NEWLY DIAGNOSED OR RECURRENT GLIOBLASTOMA

Abnormal CD8 T cells induce and track Alzheimer’s-like neurodegeneration

scientific article published on 26 February 2021

Age‐related resident memory CD8 T cells link amyloid to NFTs and neurodegeneration in mice and are modulated in AD and MCI blood

scientific article published in December 2020

Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration

scientific article published on 16 July 2024

Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration

scientific article published on 22 January 2024

CD103 Deficiency Promotes Autism (ASD) and Attention-Deficit Hyperactivity Disorder (ADHD) Behavioral Spectra and Reduces Age-Related Cognitive Decline

scientific article published in 2020

COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications

scientific article published on 01 January 2020

Cellular immunity in the treatment of brain tumors

scientific article published in January 2004

Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity

scientific article published on February 2004

Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination

scientific article published in August 2004

Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy

scientific article

DCVax-Brain and DC vaccines in the treatment of GBM

scientific article published on 01 April 2009

Dendritic cell vaccines and immunity in glioma patients

scientific article

Dendritic cell vaccines and obstacles to beneficial immunity in glioma patients

scientific article

Dendritic cell vaccines to combat glioblastoma

scientific article published in April 2010

Emergency room visits by pediatric fracture patients treated with cast immobilization

scientific article published on April 2010

Exploitation of adaptive evolution in glioma treatment

scientific article published on March 2013

Functional recreation of age-related CD8 T cells in young mice identifies drivers of aging- and human-specific tissue pathology

scientific article published on 07 September 2020

Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-1

scientific article published in June 2023

HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells

scientific article published on July 2004

Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis

scientific article

IMCT-12A PHASE 1 TRIAL OF VACCINATION WITH AUTOLOGOUS DENDRITIC CELLS PULSED WITH LYSATE DERIVED FROM AN ALLOGENEIC GLIOBLASTOMA STEM-LIKE CELL LINE FOR PATIENTS WITH NEWLY DIAGNOSED OR RECURRENT GLIOBLASTOMA.

scientific article

In situ adenoviral interleukin 12 gene transfer confers potent and long-lasting cytotoxic immunity in glioma

scientific article published in January 2002

Intratumoral T cell subset ratios and Fas ligand expression on brain tumor endothelium

scientific article

Intrinsically de-sialylated CD103(+) CD8 T cells mediate beneficial anti-glioma immune responses

scientific article

MMR Vaccination: A Potential Strategy to Reduce Severity and Mortality of COVID-19 Illness

scientific article published on 23 October 2020

Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant glioma

scientific article published on July 2003

Neuroscience20 (BRAIN20, SPINE20, and MENTAL20) Health Initiative: A Global Consortium Addressing the Human and Economic Burden of Brain, Spine, and Mental Disorders Through Neurotech Innovations and Policies

scientific article published in 2021

Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma

scientific article published on 31 July 2012

T cells enhance stem-like properties and conditional malignancy in gliomas

scientific article

T-Lymphocyte Deficiency Exacerbates Behavioral Deficits in the 6-OHDA Unilateral Lesion Rat Model for Parkinson's Disease

scientific article

Thymic CD8+ T Cell Production Strongly Influences Tumor Antigen Recognition and Age-Dependent Glioma Mortality

scientific article published on November 1, 2003

Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression

scientific article

Transcriptomic profiling of human peritumoral neocortex tissues revealed genes possibly involved in tumor-induced epilepsy

scientific article

Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients

scientific article

Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma

scientific article published in July 2004

Vaccines for glioblastoma and high-grade glioma

scientific article published on June 1, 2011

hHSS1: a novel secreted factor and suppressor of glioma growth located at chromosome 19q13.33

scientific article published on July 31, 2010