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List of works by Jan C. Oosterwijk

"It Is What It Is".

scientific article published on 16 February 2016

A DGGE system for comprehensive mutation screening ofBRCA1andBRCA2: application in a Dutch cancer clinic setting

article

A counselee-oriented perspective on risk communication in genetic counseling: Explaining the inaccuracy of the counseleesʼ risk perception shortly after BRCA1/2 test result disclosure

scientific article published on 01 September 2011

A method to assess the clinical significance of unclassified variants in the BRCA1 and BRCA2 genes based on cancer family history

scientific article published on 06 February 2009

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

scientific article

A simple method for co-segregation analysis to evaluate the pathogenicity of unclassified variants; BRCA1 and BRCA2 as an example

scientific article published on 29 June 2009

Accuracy of family history of cancer: clinical genetic implications

article published in 2000

Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families

scientific article published on 11 June 2019

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

scientific article published on 25 April 2015

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Autosomal recessive HEM/Greenberg skeletal dysplasia is caused by 3 beta-hydroxysterol delta 14-reductase deficiency due to mutations in the lamin B receptor gene

scientific article

BRCA1-associated breast cancers present differently from BRCA2-associated and familial cases: long-term follow-up of the Dutch MRISC Screening Study

scientific article

Benign familial infantile convulsions: a clinical study of seven Dutch families

scientific article published on 01 January 2002

Bias Correction Methods Explain Much of the Variation Seen in Breast Cancer Risks of BRCA1/2 Mutation Carriers

scientific article

Bias Explains Most of the Parent-of-Origin Effect on Breast Cancer Risk in BRCA1/2 Mutation Carriers

scientific article

Bone mineral density and fractures after risk-reducing salpingo-oophorectomy in women at increased risk for breast and ovarian cancer.

scientific article published on 18 December 2014

Breast Cancer Incidence After Risk-Reducing Salpingo-Oophorectomy in BRCA1 and BRCA2 Mutation Carriers

scientific article published on 25 September 2012

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations

scientific article published on 27 November 2013

Breast cancer screening in BRCA1 and BRCA2 mutation carriers after risk reducing salpingo-oophorectomy

scientific article published on 04 March 2011

Breast density as indicator for the use of mammography or MRI to screen women with familial risk for breast cancer (FaMRIsc): a multicentre randomized controlled trial

scientific article

CDC73-Related Disorders: Clinical Manifestations and Case Detection in Primary Hyperparathyroidism.

scientific article published on 12 October 2017

CHEK2-mutation in Dutch breast cancer families: expanding genetic testing for breast cancer

scientific article published in January 2015

Cholesterol profile in women with premature menopause after risk reducing salpingo-oophorectomy

scientific article published on 01 January 2019

Clinicopathologic characteristics and survival in BRCA1- and BRCA2-related adnexal cancer: are they different?

scientific article published in May 2012

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

scientific article

Cost-effectiveness of Breast Cancer Screening With Magnetic Resonance Imaging for Women at Familial Risk

scientific article published on 30 July 2020

Cost-effectiveness of screening women with familial risk for breast cancer with magnetic resonance imaging

scientific article published on 12 August 2013

Design of the BRISC study: a multicentre controlled clinical trial to optimize the communication of breast cancer risks in genetic counselling

scientific article

Differences in natural history between breast cancers in BRCA1 and BRCA2 mutation carriers and effects of MRI screening-MRISC, MARIBS, and Canadian studies combined

scientific article published on 28 June 2012

Do BRCA1/2 mutation carriers have an earlier onset of natural menopause?

scientific article published on 20 June 2016

Do Preferred Risk Formats Lead to Better Understanding? A Multicenter Controlled Trial on Communicating Familial Breast Cancer Risks Using Different Risk Formats

scientific article published on 19 February 2020

Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition

scientific article published in July 2004

Elevated Bone Turnover Markers after Risk-Reducing Salpingo-Oophorectomy in Women at Increased Risk for Breast and Ovarian Cancer

scientific article

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

scientific article

Exploring the short-term impact of DNA-testing in breast cancer patients: the counselees' perception matters, but the actual BRCA1/2 result does not.

scientific article published on 27 December 2011

Exposure to low-dose radiation and the risk of breast cancer among women with a familial or genetic predisposition: a meta-analysis

scientific article

Factors affecting sensitivity and specificity of screening mammography and MRI in women with an inherited risk for breast cancer

scientific article published on 22 June 2006

Functional categorization of BRCA1 variants of uncertain clinical significance in homologous recombination repair complementation assays

scientific article published on 16 June 2020

Genetic control of tumor development in malformation syndromes

scientific article published on 03 November 2020

Genetic counseling does not fulfill the counselees' need for certainty in hereditary breast/ovarian cancer families: an explorative assessment

scientific article published on 09 July 2012

Genetic testing and familial implications in breast-ovarian cancer families

scientific article published on 09 May 2014

Genotype-phenotype correlations for pancreatic cancer risk in Dutch melanoma families with pathogenic CDKN2A variants

scientific article published on 01 June 2020

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

scientific article published on 01 April 2019

Hereditary Breast-Ovarian Cancer Team of the University Medical Centre Groningen (UMCG) - a Report

scientific article

Hereditary breast cancer growth rates and its impact on screening policy

scientific article

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Inheritance of most X-linked traits is not dominant or recessive, just X-linked

scientific article

Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers

scientific article published on 16 September 2019

Inverse birth cohort effects in ovarian cancer: Increasing risk in BRCA1/2 mutation carriers and decreasing risk in the general population.

scientific article published on 26 November 2015

Keratosis Follicularis Spinulosa Decalvans is caused by mutations in MBTPS2 ⬇️

scientific article published on October 1, 2010

MRI versus mammography for breast cancer screening in women with familial risk (FaMRIsc): a multicentre, randomised, controlled trial

scientific article published on 17 June 2019

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

scientific article published on 19 June 2019

Model of care for women at increased risk of breast and ovarian cancer

scientific article published on 09 November 2011

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Multiple tumors due to mosaic genome-wide paternal uniparental disomy

scientific article published on 18 March 2019

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

No increased susceptibility to breast cancer from combined CHEK2 1100delC genotype and the HLA class III region risk factors

scientific article published on 01 August 2005

Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (Type VIIC) and common polymorphisms in the ADAMTS2 gene

scientific article

One risk fits all?

scientific article published on 01 August 2007

Online decision support for persons having a genetic predisposition to cancer and their partners during reproductive decision-making

scientific article published on 21 December 2018

Opening the psychological black box in genetic counseling. The psychological impact of DNA testing is predicted by the counselees' perception, the medical impact by the pathogenic or uninformative BRCA1/2-result

scientific article

Optimal age to start preventive measures in women withBRCA1/2mutations or high familial breast cancer risk

scientific article published on 13 February 2013

Ovarian cancer in BRCA1/2 mutation carriers: The impact of mutation position and family history on the cancer risk

scientific article published on 9 July 2015

Ovarian stimulation for IVF and risk of primary breast cancer in BRCA1/2 mutation carriers

scientific article published on 01 May 2018

Penetrance of breast cancer, ovarian cancer and contralateral breast cancer in BRCA1 and BRCA2 families: high cancer incidence at older age.

scientific article published on 4 March 2010

Predictability of BRCA1/2 mutation status in patients with ovarian cancer: How to select women for genetic testing in middle-income countries.

scientific article published on 4 June 2017

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition

scientific article published on 4 January 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

scientific article

Proven non-carriers in BRCA families have an earlier age of onset of breast cancer.

scientific article published on 13 March 2013

Rare variants in XRCC2 as breast cancer susceptibility alleles

scientific article published on October 2012

Relevance and efficacy of breast cancer screening in BRCA1 and BRCA2 mutation carriers above 60 years: a national cohort study

scientific article published on 20 May 2014

Reproductive decision-making in the context of hereditary cancer: the effects of an online decision aid on informed decision-making

scientific article published on 02 September 2020

Risk-reducing mastectomy in BRCA1/2 mutation carriers: factors influencing uptake and timing

scientific article published in November 2013

Serum AMH levels in healthy women from BRCA1/2 mutated families: are they reduced?

scientific article published on 5 October 2016

Should women with a BRCA1/2 mutation aged 60 and older be offered intensified breast cancer screening? - A cost-effectiveness analysis

scientific article published on 12 March 2019

Stopping ovarian cancer screening in BRCA1/2 mutation carriers: effects on risk management decisions & outcome of risk-reducing salpingo-oophorectomy specimens

scientific article

Support of the 'fallopian tube hypothesis' in a prospective series of risk-reducing salpingo-oophorectomy specimens.

scientific article published on 21 August 2012

Survival benefit in women with BRCA1 mutation or familial risk in the MRI screening study (MRISC).

scientific article published on 17 April 2015

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study

scientific article

The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium

scientific article published on 10 May 2017

The BRCA1/2 Parent-of-Origin Effect on Breast Cancer Risk-Response

scientific article published on 01 February 2017

The Dutch founder mutation SDHD.D92Y shows a reduced penetrance for the development of paragangliomas in a large multigenerational family

scientific article

The HLA class III subregion is responsible for an increased breast cancer risk

scientific article published on 22 July 2003

The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With or Mutations

The association between cancer family history and ovarian cancer risk in BRCA1/2 mutation carriers: can it be explained by the mutation position?

scientific article published on 26 February 2018

The counselees' self-reported request for psychological help in genetic counseling for hereditary breast/ovarian cancer: not only psychopathology matters

article by Joël Vos et al published 27 June 2012 in Psycho-Oncology

The decision evaluation scales

scientific article published on 01 June 2005

The development of an online decision aid to support persons having a genetic predisposition to cancer and their partners during reproductive decision-making: a usability and pilot study.

scientific article published in January 2019

The effectiveness of a graphical presentation in addition to a frequency format in the context of familial breast cancer risk communication: a multicenter controlled trial

scientific article

The validation of a simulation model incorporating radiation risk for mammography breast cancer screening in women with a hereditary-increased breast cancer risk

scientific article published on 26 November 2009

Time to stop ovarian cancer screening in BRCA1/2 mutation carriers?

scientific article published in February 2009

Variation in mutation spectrum partly explains regional differences in the breast cancer risk of female BRCA mutation carriers in the Netherlands

scientific article

[Genetic testing in patients with cancer; new developments]

scientific article published on 20 May 2019

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