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List of works by Johannes H.A.M. Kaanders

"Combined 18F-FDG-PET/CT imaging in radiotherapy target delineation for head-and-neck cancer": in regard to Guido et al. (Int J Radiat Oncol Biol Phys 2009;73:759-763).

scientific article

111In-cetuximab-F(ab')2 SPECT and 18F-FDG PET for prediction and response monitoring of combined-modality treatment of human head and neck carcinomas in a mouse model

scientific article published on 31 December 2014

111In-cetuximab-F(ab')2 SPECT imaging for quantification of accessible epidermal growth factor receptors (EGFR) in HNSCC xenografts

scientific article published on 7 August 2013

18F-FDG PET early response evaluation of locally advanced non-small cell lung cancer treated with concomitant chemoradiotherapy

scientific article published on 17 July 2013

18F-FDG and 18F-FLT do not discriminate between reactive and metastatic lymph nodes in oral cancer.

scientific article published on 17 February 2009

18F-FDG-PET/CT-based treatment planning for definitive (chemo)radiotherapy in patients with head and neck squamous cell carcinoma improves regional control and survival

scientific article published on 19 August 2019

18F-FLT PET does not discriminate between reactive and metastatic lymph nodes in primary head and neck cancer patients.

scientific article published in May 2007

18F-FLT PET during radiotherapy or chemoradiotherapy in head and neck squamous cell carcinoma is an early predictor of outcome

scientific article

18F-FLT PET/CT for early response monitoring and dose escalation in oropharyngeal tumors

scientific article published on 19 May 2010

A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer

scientific article published on 02 July 2013

A meta-analysis on the surgical management of paraganglioma of the carotid body per Shamblin class

scientific article published on 15 April 2018

A practical approach to assess clinical planning tradeoffs in the design of individualized IMRT treatment plans

scientific article published on 11 November 2010

A retrospective analysis of the prognosis of prostate cancer patients with lymph node involvement on MR lymphography: who might be cured ⬇️

scientific article published on July 30, 2013

ARCON: a novel biology-based approach in radiotherapy

scientific article

ARCON: experience in 215 patients with advanced head-and-neck cancer.

scientific article published in March 2002

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

scientific article published on March 2008

Adenosquamous carcinoma of the head and neck: report of 20 cases and review of the literature ⬇️

scientific article published on July 10, 2013

Advances in cancer imaging require renewed radiotherapy dose and target volume concepts

scientific article published on 23 April 2020

An Endorectal Balloon Reduces Intrafraction Prostate Motion During Radiotherapy ⬇️

scientific article published on November 16, 2011

Anal wall sparing effect of an endorectal balloon in 3D conformal and intensity-modulated prostate radiotherapy

scientific article published on 10 June 2009

Arterial baroreflex and peripheral chemoreflex function after radiotherapy for laryngeal or pharyngeal cancer

scientific article

Author's response to letter to the editor "regarding JHAMKaanders et al. "Advances in cancer imaging require renewed radiotherapy dose and target volume concepts"

scientific article published on 05 June 2020

BOLD MRI response to hypercapnic hyperoxia in patients with meningiomas: correlation with Gadolinium-DTPA uptake rate

scientific article published in July 2004

Benefit of particle therapy in re-irradiation of head and neck patients. Results of a multicentric in silico ROCOCO trial

scientific article

Biological surrogate end-points in cancer trials: potential uses, benefits and pitfalls

scientific article

Bladder filling variation during radiation treatment of prostate cancer: can the use of a bladder ultrasound scanner and biofeedback optimize bladder filling?

scientific article published on 15 March 2006

Can FDG PET predict radiation treatment outcome in head and neck cancer? Results of a prospective study.

scientific article

Can FDG-PET assist in radiotherapy target volume definition of metastatic lymph nodes in head-and-neck cancer?

scientific article published on 11 March 2009

Cancer recurrence after total laryngectomy: Treatment options, survival, and complications

scientific article published on 01 May 2006

Carcinoma of the larynx: the Dutch national guideline for diagnostics, treatment, supportive care and rehabilitation

scientific article

Clinical aspects and treatment of primary tracheal malignancies.

scientific article published on July 2010

Clinical evidence on PET-CT for radiation therapy planning in head and neck tumours

scientific article published on 12 August 2010

Clinical studies of hypoxia modification in radiotherapy

scientific article published in July 2004

Colocalization of carbonic anhydrase 9 expression and cell proliferation in human head and neck squamous cell carcinoma.

scientific article published in January 2005

Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines

scientific article

Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines

scientific article published in August 2005

Comparison of five segmentation tools for 18F-fluoro-deoxy-glucose-positron emission tomography-based target volume definition in head and neck cancer.

scientific article published in November 2007

Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy

scientific article published on 5 May 2010

Comparison of tumor volumes derived from glucose metabolic rate maps and SUV maps in dynamic 18F-FDG PET.

scientific article published on 15 May 2008

Compliance and efficiency before and after implementation of a clinical practice guideline for laryngeal carcinomas

scientific article published on 14 May 2006

Convex reformulation of biologically-based multi-criteria intensity-modulated radiation therapy optimization including fractionation effects

scientific article published on 21 October 2008

Correction of an image size difference between positron emission tomography (PET) and computed tomography (CT) improves image fusion of dedicated PET and CT.

scientific article published in June 2006

Correlation between tumor oxygenation and 18F-fluoromisonidazole PET data simulated based on microvessel images.

scientific article

Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts

scientific article published on 18 April 2008

Correlation of [18F]FMISO autoradiography and pimonidazole immunohistochemistry in human head and neck carcinoma xenografts

scientific article published on 20 November 2008

Correlation of segmented metabolic tumor volume with outcome--letter

scientific article published on 9 March 2010

Dasatinib Inhibits DNA Repair after Radiotherapy Specifically in pSFK-Expressing Tumor Areas in Head and Neck Xenograft Tumors.

scientific article published on August 2013

Decreased 3D observer variation with matched CT-MRI, for target delineation in Nasopharynx cancer

scientific article published on 15 March 2010

Degree of nephrotoxicity after intermediate- or high-dose cisplatin-based chemoradiotherapy in patients with locally advanced head and neck cancer

scientific article published on 28 November 2015

Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG O

scientific article published on 24 November 2017

Derivative-free generation and interpolation of convex Pareto optimal IMRT plans.

scientific article published on 23 November 2006

Differences in metabolism between adeno- and squamous cell non-small cell lung carcinomas: spatial distribution and prognostic value of GLUT1 and MCT4.

scientific article published on 6 December 2011

Distinct chromosomal aberrations in sinonasal mucosal melanoma as detected by comparative genomic hybridization

scientific article published on 01 February 2003

Dose-effect relationships for individual pelvic floor muscles and anorectal complaints after prostate radiotherapy

scientific article published on 02 December 2011

Dynamics of hypoxia, proliferation and apoptosis after irradiation in a murine tumor model

scientific article published in March 2006

Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers

scientific article published on February 2007

Early response monitoring with 18F-FDG PET and cetuximab-F(ab')2-SPECT after radiotherapy of human head and neck squamous cell carcinomas in a mouse model

scientific article published on 18 September 2014

Effect of breathing a hyperoxic hypercapnic gas mixture on the oxygenation of meningiomas; preliminary results

scientific article

Effect of hypoxia on the expression of αB-crystallin in head and neck squamous cell carcinoma

scientific article

Effect of routine follow-up after treatment for laryngeal cancer on life expectancy and mortality

scientific article published on 01 January 2007

Effectiveness and toxicity of hypofractionated high-dose intensity-modulated radiotherapy versus 2- and 3-dimensional radiotherapy in incurable head and neck cancer

scientific article published on 02 September 2015

Effects of breathing a hyperoxic hypercapnic gas mixture on blood oxygenation and vascularity of head-and-neck tumors as measured by magnetic resonance imaging

scientific article

Effects of hyperoxygenation on FDG-uptake in head-and-neck cancer

scientific article published on 3 July 2006

Efficacy and tolerance of salvage radiotherapy after radical prostatectomy, with emphasis on high-risk patients suited for adjuvant radiotherapy

scientific article published in December 2010

Employing the therapeutic operating characteristic (TOC) graph for individualised dose prescription ⬇️

scientific article published on March 7, 2013

Endorectal balloon reduces anorectal doses in post-prostatectomy intensity-modulated radiotherapy

scientific article published on 26 August 2011

Engineered microparticles delivering oxygen to enhance radiotherapy efficacy.

scientific article published on 7 December 2016

Epidermal growth factor receptor expression in laryngeal cancer predicts the effect of hypoxia modification as an additive to accelerated radiotherapy in a randomised controlled trial

scientific article published on 15 July 2013

Epidermal growth factor receptor imaging in human head and neck cancer xenografts

scientific article published on 06 August 2015

Erythropoietin receptor is not a surrogate marker for tumor hypoxia and does not correlate with survival in head and neck squamous cell carcinomas

scientific article published in August 2005

Erythropoietin to treat anaemia in patients with head and neck cancer

scientific article published in The Lancet

Evaluating adherence to the Dutch guideline for diagnosis, treatment and follow-up of laryngeal carcinomas

scientific article published in March 2005

Expression of E-cadherin and vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patients

scientific article published on 22 June 2011

Expression of EGFR under tumor hypoxia: identification of a subpopulation of tumor cells responsible for aggressiveness and treatment resistance.

scientific article

External beam radiotherapy with endocavitary boost for nasopharyngeal cancer: treatment results and late toxicity after extended follow-up

scientific article published on 16 March 2010

Gadopentetate dimeglumine and FDG uptake in liver metastases of colorectal carcinoma as determined with MR imaging and PET.

scientific article

Geographical distribution of lymph node metastases on MR lymphography in prostate cancer patients ⬇️

scientific article published on November 27, 2012

Glucose and glutamine metabolism in relation to mutational status in NSCLC histological subtypes

scientific article published on 30 October 2019

Glucose metabolism in NSCLC is histology-specific and diverges the prognostic potential of 18FDG-PET for adenocarcinoma and squamous cell carcinoma

scientific article published in October 2014

Hemoglobin level predicts outcome for vulvar cancer patients independent of GLUT-1 and CA-IX expression in tumor tissue

scientific article

High occurrence of aberrant lymph node spread on magnetic resonance lymphography in prostate cancer patients with a biochemical recurrence after radical prostatectomy

scientific article published on 02 June 2011

Histopathologic validation of 3'-deoxy-3'-18F-fluorothymidine PET in squamous cell carcinoma of the oral cavity

scientific article published on 15 April 2010

Human papillomavirus detection in fine needle aspiration cytology of lymph node metastasis of head and neck squamous cell cancer.

scientific article

Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia

scientific article published on 19 August 2009

Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer

scientific article published on 19 October 2005

Hypoxia, metabolism, and growth factor signaling in head and neck squamous cell carcinoma: correlation between primary and xenograft tumors

scientific article published on 06 November 2013

Hypoxic cell turnover in different solid tumor lines

scientific article

Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma.

scientific article published on 27 June 2014

Image Guided Brachytherapy for Cancer of the Nasal Vestibule: Local Control and Cosmesis

scientific article published on 17 November 2018

Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.

scientific article published on 14 August 2006

Imaging of epidermal growth factor receptor expression in head and neck cancer with SPECT/CT and 111In-labeled cetuximab-F(ab')2.

scientific article published on 17 October 2013

Impact of Time to Diagnosis and Treatment in Head and Neck Cancer: A Systematic Review

scientific article published on 25 February 2020

Impact of optimizing diagnostic workup and reducing the time to treatment in head and neck cancer

scientific article published on 07 July 2020

Implications of improved diagnostic imaging of small nodal metastases in head and neck cancer: Radiotherapy target volume transformation and dose de-escalation

scientific article published on 03 May 2018

Improving chemoradiation efficacy by PI3-K/AKT inhibition

scientific article

Individualized Dose Prescription for Hypofractionation in Advanced Non-Small-Cell Lung Cancer Radiotherapy: An in silico Trial

scientific article published on 13 January 2012

Individualized image-based lymph node irradiation for prostate cancer

scientific article published on 28 May 2013

Innovations in radiotherapy planning of head and neck cancers: role of PET.

scientific article published on 15 December 2009

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric in silico ROCOCO trial

scientific article published on 26 November 2018

Interaction of EGFR with the tumour microenvironment: implications for radiation treatment

scientific article published on 05 June 2013

Interim 18F-FDG PET/CT During Chemoradiation Therapy in the Management of Head and Neck Cancer Patients: A Systematic Review

scientific article published on 4 March 2017

Intratumoral Spatial Distribution of Hypoxia and Angiogenesis Assessed by 18F-FAZA and 125I-Gluco-RGD Autoradiography

article

Ipsilateral irradiation for oral and oropharyngeal carcinoma treated with primary surgery and postoperative radiotherapy

scientific article published on 25 February 2010

Is there a role for endorectal balloons in prostate radiotherapy? A systematic review

scientific article published on 05 May 2010

Long-term outcome and morbidity after treatment with accelerated radiotherapy and weekly cisplatin for locally advanced head-and-neck cancer: results of a multidisciplinary late morbidity clinic

scientific article published on 20 November 2010

Low phosphorylated AKT expression in laryngeal cancer: indications for a higher metastatic risk

scientific article published on 23 July 2013

Magnetic Resonance Lymphography Findings in Patients With Biochemical Recurrence After Prostatectomy and the Relation With the Stephenson Nomogram ⬇️

scientific article published on April 18, 2012

Malignant tumors of the nasal cavity and paranasal sinuses: long-term outcome and morbidity with emphasis on hypothalamic-pituitary deficiency

scientific article published on 27 October 2008

Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4 ⬇️

scientific article

Microenvironmental transformations by VEGF- and EGF-receptor inhibition and potential implications for responsiveness to radiotherapy

scientific article published on 4 December 2006

Modelling and simulation of [18F]fluoromisonidazole dynamics based on histology-derived microvessel maps.

scientific article published on 8 March 2011

Modelling and simulation of the influence of acute and chronic hypoxia on [18F]fluoromisonidazole PET imaging.

scientific article published on 7 March 2012

Molecular PET imaging for biology-guided adaptive radiotherapy of head and neck cancer

scientific article published on 05 September 2013

Molecular aspects of tumour hypoxia

scientific article published on 27 March 2008

Multicenter validation of recursive partitioning analysis classification for patients with squamous cell head and neck carcinoma treated with surgery and postoperative radiotherapy

scientific article published on May 2007

No detectable hypoxia in malignant salivary gland tumors: preliminary results

scientific article published on 28 October 2008

Normalcy of food intake in patients with head and neck cancer supported by combined dietary counseling and swallowing therapy: A randomized clinical trial

scientific article published in December 2014

Nutritional status, food intake, and dysphagia in long-term survivors with head and neck cancer treated with chemoradiotherapy: a cross-sectional study.

scientific article published on 4 April 2013

Optimal Normal Tissue Sparing in Craniospinal Axis Irradiation Using IMRT With Daily Intrafractionally Modulated Junction(s) ⬇️

scientific article published on February 6, 2011

Ototoxicity in locally advanced head and neck cancer patients treated with induction chemotherapy followed by intermediate or high-dose cisplatin-based chemoradiotherapy

scientific article published on 07 December 2018

Outcome and prognostic factors in olfactory neuroblastoma: a rare cancer network study

scientific article published on 16 March 2010

Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck

scientific article

PET Imaging in Head and Neck Cancer Patients to Monitor Treatment Response: A Future Role for EGFR-Targeted Imaging

scientific article published on 30 April 2015

PET of EGFR with (64) Cu-cetuximab-F(ab')2 in mice with head and neck squamous cell carcinoma xenografts

scientific article published on 4 August 2015

PET of hypoxia with 89Zr-labeled cG250-F(ab')2 in head and neck tumors.

scientific article

PET-CT for radiotherapy treatment planning and response monitoring in solid tumors

scientific article published on 25 January 2011

PET-CT for response assessment and treatment adaptation in head and neck cancer

scientific article published on 10 March 2010

PET/CT: panacea, redundancy, or something in between?

scientific article published on January 2004

Pathology-based validation of FDG PET segmentation tools for volume assessment of lymph node metastases from head and neck cancer

scientific article

Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: in regard to Evans et al. (Int J Radiat Oncol Biol Phys 2007;69:1024-1031).

scientific article published in April 2008

Patterns of Recurrence in Electively Irradiated Lymph Node Regions After Definitive Accelerated Intensity Modulated Radiation Therapy for Head and Neck Squamous Cell Carcinoma

scientific article published on 13 December 2015

Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy

scientific article

Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.

scientific article published in December 2002

Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: an ASTRO-ESTRO consensus statement

scientific article published on 14 April 2020

Prevalence and clinical and psychological correlates of high fear of cancer recurrence in patients newly diagnosed with head and neck cancer

scientific article published on 07 June 2019

Prognostic Value of Head and Neck Tumor Proliferative Sphericity From 3’-Deoxy-3’-[18F] Fluorothymidine Positron Emission Tomography

Quality of life of patients with locally advanced head and neck cancer treated with induction chemotherapy followed by cisplatin-containing chemoradiotherapy in the Dutch CONDOR study: a randomized controlled trial.

scientific article published on 11 December 2017

Radiolabeled cetuximab: dose optimization for epidermal growth factor receptor imaging in a head-and-neck squamous cell carcinoma model

scientific article published in December 2010

Radiotherapy in the treatment of extracranial hemangiopericytoma/solitary fibrous tumor: Study from the Rare Cancer Network

scientific article published on 02 December 2019

Radiotherapy in the treatment of mucosal melanoma of the upper aerodigestive tract: analysis of 74 cases. A Rare Cancer Network study

scientific article published on 2 May 2006

Randomized controlled trial to identify the optimal radiotherapy scheme for palliative treatment of incurable head and neck squamous cell carcinoma

scientific article published on 14 May 2020

Reduced late rectal mucosal changes after prostate three-dimensional conformal radiotherapy with endorectal balloon as observed in repeated endoscopy

scientific article published in March 2007

Reduction of Treatment Volume and Radiation Doses to Surrounding Tissues With Intraprostatic Gold Markers in Prostate Cancer Radiotherapy ⬇️

scientific article published on 08 September 2011

Regarding Davis et al.: Assessment of (18)F PET signals for automatic target volume definition in radiotherapy treatment planning

scientific article published on 10 January 2007

Reirradiation of head and neck cancer: Long-term disease control and toxicity.

scientific article published on 6 March 2017

Reprint of: Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: An ASTRO-ESTRO consensus statement

scientific article published on 27 July 2020

Screening for local and regional cancer recurrence in patients curatively treated for laryngeal cancer: Definition of a high-risk group and estimation of the lead time

scientific article published on 01 May 2007

Semiautomatic methods for segmentation of the proliferative tumour volume on sequential FLT PET/CT images in head and neck carcinomas and their relation to clinical outcome.

scientific article published on 18 December 2013

Set-up improvement in head and neck radiotherapy using a 3D off-line EPID-based correction protocol and a customised head and neck support

scientific article published in August 2003

Spatial relationship of phosphorylated epidermal growth factor receptor and activated AKT in head and neck squamous cell carcinoma.

scientific article

Surgery, radiotherapy or a combined modality for jugulotympanic paraganglioma of Fisch class C and D

scientific article published on 26 September 2018

Systematic analysis of 18F-FDG PET and metabolism, proliferation and hypoxia markers for classification of head and neck tumors

scientific article

Targeted Intervention to Improve the Quality of Head and Neck Radiation Therapy Treatment Planning in the Netherlands: Short and Long-Term Impact

scientific article published on 12 July 2019

Targeting hypoxia, HIF-1, and tumor glucose metabolism to improve radiotherapy efficacy.

scientific article published on October 2012

The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer

scientific article published on June 2009

The prognostic role of comorbidity in salivary gland carcinoma

scientific article published in October 2008

The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON

scientific article published on 26 May 2006

The role of hypofractionation radiotherapy for diffuse intrinsic brainstem glioma in children: a pilot study

scientific article

Time patterns of recurrence and second primary tumors in a large cohort of patients treated for oral cavity cancer

scientific article published on 10 August 2019

Tumor control of cervical lymph node metastases of unknown primary origin: the impact of the radiotherapy target volume

scientific article published on 25 February 2020

Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers

scientific article

Tumor microenvironment in head and neck squamous cell carcinomas: predictive value and clinical relevance of hypoxic markers. A review

scientific article published on June 2007

Tumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor model

scientific article

Tumor to cervical spinal cord standardized uptake ratio (SUR) improves the reproducibility of 18F-FDG-PET based tumor segmentation in head and neck squamous cell carcinoma in a multicenter setting

scientific article published on 10 July 2018

Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas

scientific article published on 06 August 2007

Undertreatment of tracheal carcinoma: multidisciplinary audit of epidemiologic data.

scientific article

Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma

scientific article

Value of routine follow-up for patients cured of laryngeal carcinoma

scientific article published on 01 September 2004

Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinomas

scientific article published in September 2002

What is the role of radiotherapy in the treatment of mucosal melanoma of the head and neck?

scientific article published on 05 September 2007

αB-crystallin expression is correlated with phospho-ERK1/2 expression in human breast cancer.

scientific article published on October 2013

αB-crystallin stimulates VEGF secretion and tumor cell migration and correlates with enhanced distant metastasis in head and neck squamous cell carcinoma

scientific article

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