List of works - Tao Yang

(1R,5S)-8-(2-Fluoro-4-nitrophenyl)-8-azabicyclo[3.2.1]octan-3-one ⬇️

scientific article published on November 12, 2011

3H-1,2,4-Dithiazol-3-one compounds as novel potential affordable antitubercular agents ⬇️

scientific article published on January 4, 2013

<i>N</i>-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms

scientific article published on 30 November 2020

A Novel Small Molecule, ZY354, Inhibits Dental Caries-Associated Oral Biofilms

scientific article published on 25 April 2019

A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3)

scientific article published on 01 November 2018

Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities

scientific article published on April 2014

Carrier-free nanoassemblies of a novel oxazolidinone compound FYL-67 display antimicrobial activity on methicillin-resistant Staphylococcus aureus ⬇️

scientific article published on November 19, 2012

Chemistry-based functional proteomics for drug target deconvolution

scientific article

Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms"

scientific article published on 27 January 2020

Design and synthesis of novel pyrimidine derivatives as potent antitubercular agents

scientific article published on 26 November 2018

Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors

scientific article published on 23 May 2016

Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis

scientific article published on 04 June 2018

Design, synthesis and discovery of 2(1H)-quinolone derivatives for the treatment of pulmonary fibrosis through inhibition of TGF-β/smad dependent and independent pathway

scientific article published on 06 April 2020

Design, synthesis and evaluation of novel molecules with a diphenyl ether nucleus as potential antitubercular agents ⬇️

scientific article published on December 9, 2011

Design, synthesis, and antibacterial evaluation of novel derivatives of NPS-2143 for the treatment of methicillin-resistant S. aureus (MRSA) infection

scientific article published on 02 April 2019

Dihydrofolate reductase inhibitors for use as antimicrobial agents

scientific article published on 01 April 2020

Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo

scientific article published on 20 February 2020

Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms

scientific article published on 08 November 2019

Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies

scientific article published on 27 July 2015

Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria

scientific article published on 03 July 2018

Discovery of napabucasin derivatives for the treatment of tuberculosis

scientific article published on 16 July 2019

Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a]quinoxaline-based scaffold

scientific article published on 02 May 2018

Discovery of novel bis-oxazolidinone compounds as potential potent and selective antitubercular agents.

scientific article published on 15 February 2014

Efficacy of the novel oxazolidinone compound FYL-67 for preventing biofilm formation by Staphylococcus aureus

scientific article published on 04 July 2014

Efficient discovery of novel antimicrobials through integration of synthesis and testing in crude ribosome extract

scientific article published on 01 May 2019

Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia

scientific article published on 15 April 2019

Improving the pharmacokinetics and tissue distribution of pyrinezolid by self-assembled polymeric micelles

scientific article published on 8 May 2017

Local Scaffold Diversity-Contributed Generator for Discovering Potential NLRP3 Inhibitors

scholarly article

Orlistat, a novel potent antitumor agent for ovarian cancer: proteomic analysis of ovarian cancer cells treated with Orlistat

scientific article published on 8 May 2012

Phosphoinositide 3-kinase δ/γ inhibition does not prevent concanavalin A-induced hepatitis

scientific article

Proteomics revisits the cancer metabolome

scientific article published on August 2011

Repurposed drug candidates for antituberculosis therapy

scientific article published on 25 February 2020

Repurposing Napabucasin as an Antimicrobial Agent against Oral Streptococcal Biofilms

scientific article published on 20 November 2020

SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines

scientific article published on 22 May 2018

Scaffold Hopping Toward Agomelatine: Novel 3, 4-Dihydroisoquinoline Compounds as Potential Antidepressant Agents

scientific article

Structure-activity relationship study of DEL-22379: ERK dimerization inhibitors with increased safety

scientific article published on 06 May 2020

Syntheses and Cell-Based Phenotypic Screen of Novel 7-Amino pyrido[2,3-d]pyrimidine-6-carbonitrile Derivatives as Potential Antiproliferative Agents ⬇️

scientific article published on February 24, 2012

Synthesis and biological evaluation of 2-(3-fluoro-4-nitro phenoxy)-n-phenylacetamide derivatives as novel potential affordable antitubercular agents.

scientific article

Synthesis and evaluation of amide side-chain modified Agomelatine analogues as potential antidepressant-like agents

scientific article published on 5 March 2014

TAK1 inhibition by natural cyclopeptide RA-V promotes apoptosis and inhibits protective autophagy in Kras-dependent non-small-cell lung carcinoma cells

scholarly article published in 2018

The in vivo and in vitro phase I metabolism of FYL-67, a novel oxazolidinone antibacterial drug, studied by LC-MS/MS.

scientific article published on 16 October 2015

List of works by Tao Yang

(1R*,5S*)-8-(2-Fluoro-4-nitrophenyl)-8-azabicyclo[3.2.1]octan-3-one ⬇️

3H-1,2,4-Dithiazol-3-one compounds as novel potential affordable antitubercular agents ⬇️

<i>N</i>-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms

A Novel Small Molecule, ZY354, Inhibits Dental Caries-Associated Oral Biofilms

A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3)

Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities

Carrier-free nanoassemblies of a novel oxazolidinone compound FYL-67 display antimicrobial activity on methicillin-resistant Staphylococcus aureus ⬇️

Chemistry-based functional proteomics for drug target deconvolution

Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms"

Design and synthesis of novel pyrimidine derivatives as potent antitubercular agents

Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors

Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis

Design, synthesis and discovery of 2(1H)-quinolone derivatives for the treatment of pulmonary fibrosis through inhibition of TGF-β/smad dependent and independent pathway

Design, synthesis and evaluation of novel molecules with a diphenyl ether nucleus as potential antitubercular agents ⬇️

Design, synthesis, and antibacterial evaluation of novel derivatives of NPS-2143 for the treatment of methicillin-resistant S. aureus (MRSA) infection

Dihydrofolate reductase inhibitors for use as antimicrobial agents

Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo

Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms

Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies

Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria

Discovery of napabucasin derivatives for the treatment of tuberculosis

Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a]quinoxaline-based scaffold

Discovery of novel bis-oxazolidinone compounds as potential potent and selective antitubercular agents.

Efficacy of the novel oxazolidinone compound FYL-67 for preventing biofilm formation by Staphylococcus aureus

Efficient discovery of novel antimicrobials through integration of synthesis and testing in crude ribosome extract

Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia

Improving the pharmacokinetics and tissue distribution of pyrinezolid by self-assembled polymeric micelles

Local Scaffold Diversity-Contributed Generator for Discovering Potential NLRP3 Inhibitors

Orlistat, a novel potent antitumor agent for ovarian cancer: proteomic analysis of ovarian cancer cells treated with Orlistat

Phosphoinositide 3-kinase δ/γ inhibition does not prevent concanavalin A-induced hepatitis

Proteomics revisits the cancer metabolome

Repurposed drug candidates for antituberculosis therapy

Repurposing Napabucasin as an Antimicrobial Agent against Oral Streptococcal Biofilms

SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines

Scaffold Hopping Toward Agomelatine: Novel 3, 4-Dihydroisoquinoline Compounds as Potential Antidepressant Agents

Structure-activity relationship study of DEL-22379: ERK dimerization inhibitors with increased safety

Syntheses and Cell-Based Phenotypic Screen of Novel 7-Amino pyrido[2,3-d]pyrimidine-6-carbonitrile Derivatives as Potential Antiproliferative Agents ⬇️

Synthesis and biological evaluation of 2-(3-fluoro-4-nitro phenoxy)-n-phenylacetamide derivatives as novel potential affordable antitubercular agents.

Synthesis and evaluation of amide side-chain modified Agomelatine analogues as potential antidepressant-like agents

TAK1 inhibition by natural cyclopeptide RA-V promotes apoptosis and inhibits protective autophagy in Kras-dependent non-small-cell lung carcinoma cells

The in vivo and in vitro phase I metabolism of FYL-67, a novel oxazolidinone antibacterial drug, studied by LC-MS/MS.

(1R,5S)-8-(2-Fluoro-4-nitrophenyl)-8-azabicyclo[3.2.1]octan-3-one ⬇️