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List of works by Tao Yang

A TrkB Small Molecule Partial Agonist Rescues TrkB Phosphorylation Deficits and Improves Respiratory Function in a Mouse Model of Rett Syndrome ⬇️

scientific article published on February 1, 2012

A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity‐dependent synaptic and microglial transcriptomic changes in a late‐stage Alzheimer's mouse model

scientific article published on 23 May 2024

A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease

scientific article

A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth

scientific article published on 19 June 2016

A small-molecule TrkB ligand restores hippocampal synaptic plasticity and object location memory in Rett syndrome mice

scientific article published on July 2017

Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants

scientific article

Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic stroke

scientific article published on 24 April 2012

Downregulation of the LAR protein tyrosine phosphatase receptor is associated with increased dentate gyrus neurogenesis and an increased number of granule cell layer neurons

scientific article published on 20 February 2006

Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

scientific article published on 15 April 2019

Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts.

scientific article published on 10 January 2018

Identification of an ectodomain within the LAR protein tyrosine phosphatase receptor that binds homophilically and activates signalling pathways promoting neurite outgrowth

scientific article published in November 2005

LAR protein tyrosine phosphatase receptor associates with TrkB and modulates neurotrophic signaling pathways

scientific article published in November 2006

Leukocyte Antigen-Related Protein Tyrosine Phosphatase Receptor: A Small Ectodomain Isoform Functions as a Homophilic Ligand and Promotes Neurite Outgrowth ⬇️

scientific article published on April 15, 2003

Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment

scientific article published on 20 May 2019

Oral Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Improves Erectile Function in a Mouse Model of Cavernous Nerve Injury

scientific article published on 24 November 2020

P3‐212: A SMALL MOLECULE TRKB/TRKC NEUROTROPHIN RECEPTOR CO‐ACTIVATOR PREVENTS SYNAPTIC IMPAIRMENT IN AN AD MOUSE MODEL ⬇️

scholarly article

Partial Activation of TrkB Receptors Corrects Interneuronal Calcium Channel Dysfunction and Reduces Epileptogenic Activity in Neocortex following Injury

scientific article published on 03 June 2020

Partial TrkB receptor activation suppresses cortical epileptogenesis through actions on parvalbumin interneurons

scientific article published on 2 February 2018

Protein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase function

scientific article

Restoration of motor learning in a mouse model of Rett syndrome following long-term treatment with a novel small-molecule activator of TrkB

scientific article published on 27 November 2020

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

scientific article

Small molecule approaches for promoting neurogenesis

scientific article

Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies

scientific article published on 23 November 2020

Small molecule neurotrophin receptor ligands: novel strategies for targeting Alzheimer's disease mechanisms

scientific article

Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model.

scientific article published on 29 March 2013

Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice

scientific article

Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment

scientific article

Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death.

scientific article published in May 2006

Small-molecule modulation of the p75 neurotrophin receptor inhibits a wide range of tau molecular pathologies and their sequelae in P301S tauopathy mice

scientific article published on 05 September 2020

The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo

scientific article published on August 2009

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