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List of works by Ronald A. Bush

A retinal neuronal developmental wave of retinoschisin expression begins in ganglion cells during layer formation

scientific article published in September 2004

Ames Waltzer deaf mice have reduced electroretinogram amplitudes and complex alternative splicing of Pcdh15 transcripts

scientific journal article

CNGB3-achromatopsia clinical trial with CNTF: diminished rod pathway responses with no evidence of improvement in cone function

scientific article

Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants

scholarly article

Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function

scholarly article

Identification and characterization of two mature isoforms of retinoschisin in murine retina

scientific article published on 10 August 2006

Intravitreal Ciliary Neurotrophic Factor Transiently Improves Cone-Mediated Function in a CNGB3-/- Mouse Model of Achromatopsia

scientific article

Loss of Retinoschisin (RS1) Cell Surface Protein in Maturing Mouse Rod Photoreceptors Elevates the Luminance Threshold for Light-Driven Translocation of Transducin But Not Arrestin ⬇️

scientific article published on September 19, 2012

NADPH Oxidase Contributes to Photoreceptor Degeneration in Constitutively Active RAC1 Mice

scientific article published on May 2016

Ocular and systemic safety of a recombinant AAV8 vector for X-linked retinoschisis gene therapy: GLP studies in rabbits and Rs1-KO mice

scientific article published on 16 March 2016

Organization and molecular interactions of retinoschisin in photoreceptors

scientific article published on January 2008

Photoreceptor pathology in the X-linked retinoschisis (XLRS) mouse results in delayed rod maturation and impaired light driven transducin translocation

scientific article

Preclinical Dose-Escalation Study of Intravitreal AAV-RS1 Gene Therapy in a Mouse Model of X-linked Retinoschisis: Dose-Dependent Expression and Improved Retinal Structure and Function

scientific article published on April 2016

Preclinical safety evaluation of a recombinant AAV8 vector for X-linked retinoschisis after intravitreal administration in rabbits

scientific article

Primate Retinal Signaling Pathways: Suppressing ON-Pathway Activity in Monkey With Glutamate Analogues Mimics Human CSNB1-NYX Genetic Night Blindness

scientific article

Probing potassium channel function in vivo by intracellular delivery of antibodies in a rat model of retinal neurodegeneration

scientific article

RS-1 Gene Delivery to an Adult Rs1h Knockout Mouse Model Restores ERG b-Wave with Reversal of the Electronegative Waveform of X-Linked Retinoschisis

scientific journal article

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism ⬇️

scientific article

Rearing Light Intensity Affects Inner Retinal Pathology in a Mouse Model of X-Linked Retinoschisis but Does Not Alter Gene Therapy Outcome

scientific article published on March 2017

Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery

article

Retinal Structure and Gene Therapy Outcome in Retinoschisin-Deficient Mice Assessed by Spectral-Domain Optical Coherence Tomography

scientific article published on July 2016

Retinoschisin is a peripheral membrane protein with affinity for anionic phospholipids and affected by divalent cations

scientific journal article

Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer

scientific article

Synaptic pathology in retinoschisis knockout (Rs1-/y) mouse retina and modification by rAAV-Rs1 gene delivery

scientific article published on August 2008

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

scientific article published on 24 June 2020

Transgenic expression of constitutively active RAC1 disrupts mouse rod morphogenesis

scientific article published on 25 April 2014

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