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List of works by Dick J Richel

5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer.

scientific article

A phase I/II, non-randomized, feasibility/safety and efficacy study of the combination of everolimus, cetuximab and capecitabine in patients with advanced pancreatic cancer.

scientific article published on 25 February 2012

A phase Ib study of everolimus combined with metformin for patients with advanced cancer

scientific article published on 15 June 2017

Activation of the canonical beta-catenin pathway by histamine

scientific article published on 16 October 2003

Altered dihydropyrimidine dehydrogenase activity associated with mild toxicity in patients treated with 5-fluorouracil containing chemotherapy

scientific article published in June 2008

Angiogenesis inhibitor DC101 delays growth of intracerebral glioblastoma but induces morbidity when combined with irradiation.

scientific article

Antithrombotic therapy and cancer

scientific article (publication date: May 2004)

Bowel perforation after radiotherapy in a patient receiving sorafenib.

scientific article published in May 2008

Cardiotoxicity of cytotoxic drugs

scientific article

Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin

scientific article (publication date: 17 May 2007)

Coagulation factors VIIa and Xa inhibit apoptosis and anoikis

scientific article published on January 2004

Dabigatran potentiates gemcitabine-induced growth inhibition of pancreatic cancer in mice

scientific article published on 6 February 2017

Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung

scientific article

Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer

scientific article

Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement

scientific article published on July 2009

Esophageal carcinoma: surgery, radiotherapy, and chemotherapy.

scientific article published on July 2002

FVIIa:TF induces cell survival via G12/G13-dependent Jak/STAT activation and BclXL production

scientific article published on 11 March 2004

Farnesyl protein transferase inhibition interferes with activation of MAP kinase family members in human peripheral blood monocytes

scientific article published on December 2002

Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.

scientific article published on 15 February 2012

High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.

scientific article published on July 2003

Intensive care admission of cancer patients: a comparative analysis

scientific article published on 18 April 2015

LPS signal transduction: the picture is becoming more complex

scientific article published in January 2004

Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial

scientific article published on 8 June 2015

Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients

scientific article published in November 2011

Neoadjuvant chemoradiotherapy has a potential role in pancreatic carcinoma ⬇️

scientific article published on January 1, 2011

Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies ⬇️

scientific article published on August 2, 2011

Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development

scientific article

Predicting early failure after adjuvant chemotherapy in high-risk breast cancer patients with extensive lymph node involvement

scientific article published in July 2004

Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.

scientific article published on April 2006

Preoperative chemoradiotherapy in locally advanced gastric cancer, a phase I/II feasibility and efficacy study

scientific article published on 22 May 2014

Prophylactic plasma levels of the low molecular weight heparin nadroparin does not affect colon cancer tumor development in mouse liver

scientific article published on 15 April 2009

Prostanoids and prostanoid receptors in signal transduction

scientific article (publication date: July 2004)

Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity

scientific article published on 25 May 2006

Quality of life versus prolongation of life in patients treated with chemotherapy in advanced colorectal cancer: A review of randomized controlled clinical trials

scientific article

Randomized Trial of the Effect of the Low Molecular Weight Heparin Nadroparin on Survival in Patients With Cancer ⬇️

scientific article published on April 18, 2011

Symptomatic venous thromboembolism in cancer patients treated with chemotherapy: an underestimated phenomenon

scientific article published in January 2004

Targeting Wnt signaling in colon cancer stem cells

scientific article published on 15 December 2010

The developing cancer stem-cell model: clinical challenges and opportunities

scientific article published on February 2012

The effect of low molecular weight heparin on survival in patients with advanced malignancy

scientific article published on 7 February 2005

Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways

scientific article published in January 2004

Tumour control by whole brain irradiation of anti-VEGF-treated mice bearing intracerebral glioma.

scientific article

Understanding palliative cancer chemotherapy: about shared decisions and shared trajectories

scientific article

VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation

scientific article

Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals

scientific article published on July 2007

Vascular endothelial growth factor in the circulation in cancer patients may not be a relevant biomarker

scientific article

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

scientific article (publication date: May 2010)

[The treatment of hepatocellular carcinoma. New developments].

scientific article published in April 2009

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