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List of works by Wim H J Kruit

Adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation after resection of primary tumor > 1.5 mm in patients with stage II melanoma: results of the EORTC 18961 randomized phase III trial

scientific article

Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial

scientific article

Analysis of surrogate gene expression markers in peripheral blood of melanoma patients to predict treatment outcome of adjuvant pegylated interferon alpha 2b (EORTC 18991 side study).

scientific article published on 27 April 2013

Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon

scientific article

Changes of ferritin and CRP levels in melanoma patients treated with adjuvant interferon-α (EORTC 18952) and prognostic value on treatment outcome

scientific article published on 01 August 2011

Circulating melanoma cells and distant metastasis-free survival in stage III melanoma patients with or without adjuvant interferon treatment (EORTC 18991 side study).

scientific article published on 28 September 2009

Dacarbazine, cisplatin, and interferon-alfa-2b with or without interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organisation for Research and Treatment of Cancer Melanoma Group

scientific article published in September 2005

Dutch Melanoma Treatment Registry: Quality assurance in the care of patients with metastatic melanoma in the Netherlands.

scientific article published on 25 December 2016

Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032).

scientific article

IL-12: a promising adjuvant for cancer vaccination

scientific article published on 12 February 2003

Interferon-alpha in oncology patients: fewer psychiatric side effects than anticipated

scientific article published on 01 January 2008

Interferon-alpha influences tryptophan metabolism without inducing psychiatric side effects

scientific article published on 17 September 2007

Long-term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma

scientific article published on 24 September 2012

MAGE-A3 immunotherapeutic as adjuvant therapy for patients with resected, MAGE-A3-positive, stage III melanoma (DERMA): a double-blind, randomised, placebo-controlled, phase 3 trial

scientific article published on 13 June 2018

Macrocytosis as a potential parameter associated with survival after tyrosine kinase inhibitor treatment.

scientific article published on 31 January 2016

Neuropsychiatric side effects of interferon-alfa therapy

scientific article published in February 2003

Neurotoxic and neuroprotective metabolites of kynurenine in patients with renal cell carcinoma treated with interferon-alpha: course and relationship with psychiatric status

scientific article

Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy

scientific article published on 26 October 2008

Pegylated interferon-alpha2b treatment in melanoma patients: influence on amino acids, 5-hydroxyindolacetic acid and pteridine plasma concentrations

scientific article published in July 2004

Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma

scientific article published in November 2005

Phase III trial comparing adjuvant treatment with pegylated interferon Alfa-2b versus observation: prognostic significance of autoantibodies--EORTC 18991.

scientific article

Pimasertib-associated ophthalmological adverse events

scientific article published on 16 January 2018

Platelet MAO activity during treatment with pegylated interferon-alfa in melanoma patients

scientific article published on 18 November 2004

Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial

scientific article published in October 2005

Predictive Gene Signature in MAGE-A3 Antigen-Specific Cancer Immunotherapy ⬇️

scientific article published on May 28, 2013

Pretreatment levels of peripheral neutrophils and leukocytes as independent predictors of overall survival in patients with American Joint Committee on Cancer Stage IV Melanoma: results of the EORTC 18951 Biochemotherapy Trial

scientific article published on 01 April 2007

Real-world healthcare costs of ipilimumab in patients with advanced cutaneous melanoma in The Netherlands

scientific article published on 01 July 2018

Real-world use, safety, and survival of ipilimumab in metastatic cutaneous melanoma in The Netherlands.

scientific article published on 13 April 2018

Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses.

scientific article

Revision of the national guideline 'Melanoma'

scientific article published on 01 January 2013

Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma

scientific article

Serum amino acids, biopterin and neopterin during long-term immunotherapy with interferon-alpha in high-risk melanoma patients

scientific article published in July 2003

Serum concentrations of pegylated interferon alpha-2b in patients with resected stage III melanoma receiving adjuvant pegylated interferon alpha-2b in a randomized phase III trial (EORTC 18991).

scientific article

Side effects of interferon-alpha therapy

scientific article

Stage-specific disease recurrence and survival in localized and regionally advanced cutaneous melanoma

scientific article published on 05 February 2019

Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant

scientific article

Thalidomide in solid tumours: the resurrection of an old drug

scientific article published in November 2004

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

scientific article published on 01 May 2006

Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991.

scientific article published on 5 November 2011

Vemurafenib in BRAF-mutant metastatic melanoma patients in real-world clinical practice: prognostic factors associated with clinical outcomes

scientific article published on 01 August 2018

[Improved compliance with the 'Melanoma' treatment guideline]

scientific article published on 01 January 2010

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