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List of works by Cor Breukel

A 10-Mb paracentric inversion of chromosome arm 2p inactivatesMSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North-American kindred

scientific article published on 01 September 2002

A Restricted Role for FcγR in the Regulation of Adaptive Immunity.

scientific article published on 9 March 2018

A dystrophic Duchenne mouse model for testing human antisense oligonucleotides

scientific article published on 21 February 2018

A new conditional Apc-mutant mouse model for colorectal cancer

scientific article published on 22 February 2010

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis

scientific article published on 3 July 2009

APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression

scientific article published on 16 August 2006

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

scientific article published on 11 November 2002

Axin2-mTurquoise2: A novel reporter mouse model for the detection of canonical Wnt signalling.

scientific article published on 5 September 2017

CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses

scholarly article

FcγR interaction is not required for effective anti-PD-L1 immunotherapy but can add additional benefit depending on the tumor model

scientific article published on 12 November 2018

FcγRI expression on macrophages is required for antibody-mediated tumor protection by cytomegalovirus-based vaccines

scientific article published on 29 June 2018

FcγRIIb on myeloid cells rather than on B cells protects from collagen-induced arthritis

scientific article published on 19 May 2014

First FHM3 mouse model shows spontaneous cortical spreading depolarizations

scientific article published on 27 December 2019

Focal and generalized seizure activity after local hippocampal or cortical ablation of NaV 1.1 channels in mice

scientific article published on 19 March 2020

High FcγR Expression on Intratumoral Macrophages Enhances Tumor-Targeting Antibody Therapy

scientific article published on 05 November 2018

Highly B lymphocyte-specific tamoxifen inducible transgene expression of CreER T2 by using the LC-1 locus BAC vector.

scientific article published in November 2009

Immunogenicity of rat-neu+ mouse mammary tumours determines the T cell-dependent therapeutic efficacy of anti-neu monoclonal antibody treatment

scientific article published on 03 March 2020

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP).

scientific article published on 22 January 2013

Involvement of Fcα/μ Receptor in IgM Anti-Platelet, but Not Anti-Red Blood Cell Autoantibody Pathogenicity in Mice

scientific article

Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene

scientific article

TSSV: a tool for characterization of complex allelic variants in pure and mixed genomes.

scientific article

The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.

scientific article published in June 2002

The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility ⬇️

scientific article published on August 1, 2011

The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation

scientific article

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