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List of works by Judith van Deutekom

A sensitive, reproducible and objective immunofluorescence analysis method of dystrophin in individual fibers in samples from patients with duchenne muscular dystrophy

scientific article published in 2014

Advances in Duchenne muscular dystrophy gene therapy ⬇️

scientific article published on October 1, 2003

Antisense oligonucleotide mediated exon skipping as a potential strategy for the treatment of a variety of inflammatory diseases such as rheumatoid arthritis

scientific article published on 01 April 2012

Antisense-induced exon skipping for duplications in Duchenne muscular dystrophy

scientific article

Antisense-induced multiexon skipping for Duchenne muscular dystrophy makes more sense

scientific article published on 16 December 2003

Antisense-mediated exon skipping to correct IL-12Rbeta1 deficiency in T cells

scientific article published on 3 March 2009

Assessment of the feasibility of exon 45-55 multiexon skipping for Duchenne muscular dystrophy

scientific article

Cell membrane integrity in myotonic dystrophy type 1: implications for therapy

scientific article

Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells.

scientific article

Design and analysis of effects of triplet repeat oligonucleotides in cell models for myotonic dystrophy

scientific article published on 19 March 2013

Development of antisense-mediated exon skipping as a treatment for duchenne muscular dystrophy

scientific article

Digital Droplet PCR for the Absolute Quantification of Exon Skipping Induced by Antisense Oligonucleotides in (Pre-)Clinical Development for Duchenne Muscular Dystrophy.

scientific article

Dose-dependent pharmacokinetic profiles of 2'-O-methyl phosphorothioate antisense oligonucleotidesin mdx mice

scientific article published on 2 May 2013

Entries in the Leiden Duchenne muscular dystrophy mutation database: an overview of mutation types and paradoxical cases that confirm the reading-frame rule

scientific article

Exon skipping for DMD.

scientific article published on 22 November 2012

Exonic sequences provide better targets for antisense oligonucleotides than splice site sequences in the modulation of Duchenne muscular dystrophy splicing

scientific article published on April 2010

Exploring the frontiers of therapeutic exon skipping for Duchenne muscular dystrophy by double targeting within one or multiple exons

scientific article published on 06 June 2006

FSHD associated DNA rearrangements are due to deletions of integral copies of a 3.2 kb tandemly repeated unit

scientific article (publication date: 1993)

Functional analysis of 114 exon-internal AONs for targeted DMD exon skipping: indication for steric hindrance of SR protein binding sites

scientific article

Gene expression profiling to monitor therapeutic and adverse effects of antisense therapies for Duchenne muscular dystrophy.

scientific article

Gene therapy: the 'pro-sense' approach to Duchenne muscular dystrophy

scientific article

Generation and Characterization of Transgenic Mice with the Full-length HumanDMDGene

scientific article published in Journal of Biological Chemistry

Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms

scientific article

Implications of maturation for viral gene delivery to skeletal muscle ⬇️

scientific article published on May 1, 1998

In vivo comparison of 2'-O-methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping

scientific article

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP).

scientific article published on 22 January 2013

Intracellular Distribution and Nuclear Activity of Antisense Oligonucleotides After Unassisted Uptake in Myoblasts and Differentiated Myotubes In Vitro.

scientific article

Large-scale gene expression analysis of human skeletal myoblast differentiation.

scientific article

Local dystrophin restoration with antisense oligonucleotide PRO051

scientific article published on 01 December 2007

Long-Term Efficacy, Safety, and Pharmacokinetics of Drisapersen in Duchenne Muscular Dystrophy: Results from an Open-Label Extension Study

scientific article

Long-term Exon Skipping Studies With 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in Dystrophic Mouse Models

scientific article

Peptide conjugation of 2'-O-methyl phosphorothioate antisense oligonucleotides enhances cardiac uptake and exon skipping in mdx mice

scientific article

Preclinical PK and PD studies on 2'-O-methyl-phosphorothioate RNA antisense oligonucleotides in the mdx mouse model

scientific article

Prednisolone Treatment Does Not Interfere with 2′-O-Methyl Phosphorothioate Antisense-Mediated Exon Skipping in Duchenne Muscular Dystrophy ⬇️

scientific article published on January 26, 2012

Report of a TREAT-NMD/World Duchenne Organisation Meeting on Dystrophin Quantification Methodology

scientific article published on 01 January 2019

Systemic administration of PRO051 in Duchenne's muscular dystrophy

scientific article

Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy

scientific article published in October 2002

Targeted exon skipping in transgenic hDMD mice: A model for direct preclinical screening of human-specific antisense oligonucleotides

scientific article

Targeting several CAG expansion diseases by a single antisense oligonucleotide

scientific article (publication date: 2011)

The Dynamics of Compound, Transcript, and Protein Effects After Treatment With 2OMePS Antisense Oligonucleotides in mdx Mice

scientific article published on 18 February 2014

The Pharmacokinetics of 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides: Experiences from Developing Exon Skipping Therapies for Duchenne Muscular Dystrophy

scientific article published on 20 August 2019

The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain.

scientific article

The therapeutic potential of antisense-mediated exon skipping

scientific article published on April 2008

Theoretic applicability of antisense-mediated exon skipping for Duchenne muscular dystrophy mutations

scientific article

Therapeutic antisense-induced exon skipping in cultured muscle cells from six different DMD patients.

scientific article

Use of capillary Western immunoassay (Wes) for quantification of dystrophin levels in skeletal muscle of healthy controls and individuals with Becker and Duchenne muscular dystrophy

scientific article published on 11 April 2018

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