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List of works by Leigh Zerboni

Aberrant infection and persistence of varicella-zoster virus in human dorsal root ganglia in vivo in the absence of glycoprotein I.

scholarly article

Age-associated differences in infection of human skin in the SCID mouse model of varicella-zoster virus pathogenesis

scientific article published on 21 March 2018

Analysis of the functions of glycoproteins E and I and their promoters during VZV replication in vitro and in skin and T-cell xenografts in the SCID mouse model of VZV pathogenesis

scientific article published on January 2010

Analysis of varicella zoster virus attenuation by evaluation of chimeric parent Oka/vaccine Oka recombinant viruses in skin xenografts in the SCIDhu mouse model

scientific article

Anti-glycoprotein H antibody impairs the pathogenicity of varicella-zoster virus in skin xenografts in the SCID mouse model

scientific article

Apparent expression of varicella-zoster virus proteins in latency resulting from reactivity of murine and rabbit antibodies with human blood group a determinants in sensory neurons

scientific article published on 19 October 2011

Autophagic flux without a block differentiates varicella-zoster virus infection from herpes simplex virus infection

scientific article

Cellular and viral factors regulate the varicella-zoster virus gE promoter during viral replication

scientific article

Construction of varicella-zoster virus recombinants from parent Oka cosmids and demonstration that ORF65 protein is dispensable for infection of human skin and T cells in the SCID-hu mouse model

scientific article

Current In Vivo Models of Varicella-Zoster Virus Neurotropism

scientific article published on 31 May 2019

Deletion of the first cysteine-rich region of the varicella-zoster virus glycoprotein E ectodomain abolishes the gE and gI interaction and differentially affects cell-cell spread and viral entry

scientific article published on 22 October 2008

Development of recombinant varicella-zoster viruses expressing luciferase fusion proteins for live in vivo imaging in human skin and dorsal root ganglia xenografts

scientific article published on 24 September 2008

Differential requirement for cell fusion and virion formation in the pathogenesis of varicella-zoster virus infection in skin and T cells

scientific article published on December 2004

Differentiation of varicella-zoster virus ORF47 protein kinase and IE62 protein binding domains and their contributions to replication in human skin xenografts in the SCID-hu mouse

scientific article

Entrapment of Viral Capsids in Nuclear PML Cages Is an Intrinsic Antiviral Host Defense against Varicella-Zoster Virus ⬇️

scientific article published on February 3, 2011

Expression of varicella-zoster virus immediate-early regulatory protein IE63 in neurons of latently infected human sensory ganglia

scientific article

Functions of Varicella-zoster virus ORF23 capsid protein in viral replication and the pathogenesis of skin infection

scientific article

Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivo

scientific article

Functions of the ORF9-to-ORF12 gene cluster in varicella-zoster virus replication and in the pathogenesis of skin infection

scientific article published on 09 April 2008

Functions of the unique N-terminal region of glycoprotein E in the pathogenesis of varicella-zoster virus infection

scientific article

Herpes Simplex Virus 1 Tropism for Human Sensory Ganglion Neurons in the Severe Combined Immunodeficiency Mouse Model of Neuropathogenesis ⬇️

scientific article published on December 26, 2012

Identification of a Hydrophobic Domain in Varicella-Zoster Virus ORF61 Necessary for ORF61 Self-Interaction, Viral Replication, and Skin Pathogenesis ⬇️

scientific article published on January 23, 2013

Investigation of varicella-zoster virus neurotropism and neurovirulence using SCID mouse-human DRG xenografts

scientific article published on 08 December 2011

Mechanisms of varicella-zoster virus neuropathogenesis in human dorsal root ganglia

scientific article published on 6 February 2008

Molecular mechanisms of varicella zoster virus pathogenesis

scientific article

Mutagenesis of varicella-zoster virus glycoprotein B: putative fusion loop residues are essential for viral replication, and the furin cleavage motif contributes to pathogenesis in skin tissue in vivo

scientific article

Mutational Analysis of Open Reading Frames 62 and 71, Encoding the Varicella-Zoster Virus Immediate-Early Transactivating Protein, IE62, and Effects on Replication In Vitro and in Skin Xenografts in the SCID-hu Mouse In Vivo ⬇️

scientific article published on May 1, 2003

Neuronal Subtype and Satellite Cell Tropism Are Determinants of Varicella-Zoster Virus Virulence in Human Dorsal Root Ganglia Xenografts In Vivo

scientific article published on 19 June 2015

ORF66 protein kinase function is required for T-cell tropism of varicella-zoster virus in vivo

scientific article

Promoter sequences of varicella-zoster virus glycoprotein I targeted by cellular transactivating factors Sp1 and USF determine virulence in skin and T cells in SCIDhu mice in vivo

scientific article

Role of the varicella-zoster virus gene product encoded by open reading frame 35 in viral replication in vitro and in differentiated human skin and T cells in vivo

scientific article

Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis ⬇️

scientific article published on December 21, 2011

T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection

scientific article

The C-terminus of varicella-zoster virus glycoprotein M contains trafficking motifs that mediate skin virulence in the SCID-human model of VZV pathogenesis

The immediate-early 63 protein of Varicella-Zoster virus: analysis of functional domains required for replication in vitro and for T-cell and skin tropism in the SCIDhu model in vivo.

scientific article published on February 2004

The latency-associated transcript locus of herpes simplex virus 1 is a virulence determinant in human skin

scientific article published on 28 December 2020

VZV: pathogenesis and the disease consequences of primary infection ⬇️

scientific article published on February 25, 2011

Varicella-zoster virus T cell tropism and the pathogenesis of skin infection

scientific article

Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis

scientific article

Varicella-zoster virus infection of human dorsal root ganglia in vivo.

scientific article

Varicella-zoster virus infection of human neural cells in vivo.

scholarly article

Varicella-zoster virus open reading frame 10 is a virulence determinant in skin cells but not in T cells in vivo

scientific article

Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alpha

scientific article

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