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List of works by Eline van der Burg

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors

scientific article

BRCA1-associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling

scientific article published on 04 July 2018

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

scientific article published on 25 July 2016

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer

scientific article published in Nature Communications

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

scientific article

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors

scientific article

In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer

scientific article published on 13 January 2020

Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma

scientific article published on 26 June 2017

MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling

scientific article published in 2022

Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice

scientific article

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer

scientific article published on 5 July 2016

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma

scientific article published on 10 August 2016

Prophylactic window therapy with the clinical poly(ADP-ribose) polymerase inhibitor olaparib delays BRCA1-deficient mammary tumour formation in mice

scientific article published on 9 December 2016

Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers

correction of a scholarly article

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin

scientific article published on 23 August 2019

Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

scientific article

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan

scientific article

Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

scientific article

TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development

scientific article published on 26 December 2019

Truncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct Mechanisms

scientific article published on 14 February 2020

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers

scientific article published in August 2022

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