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List of works by Wilfred F A den Dunnen

A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus.

scientific article published on January 2012

Anti-angiogenic therapy in pediatric brain tumors: an effective strategy?

scientific article published on 10 October 2013

Axonal inclusions in spinocerebellar ataxia type 3.

scientific article

Blood RNA biomarkers in prodromal PARK4 and rapid eye movement sleep behavior disorder show role of complexin 1 loss for risk of Parkinson's disease.

scientific article

Brain pathology of spinocerebellar ataxias

scientific article

Commentary on Special Issue: CNS Diseases and the Immune System ⬇️

scientific article published on June 12, 2013

Consistent affection of the central somatosensory system in spinocerebellar ataxia type 2 and type 3 and its significance for clinical symptoms and rehabilitative therapy

scientific article published on 2 October 2006

Desmoplastic infantile ganglioglioma with a malignant course.

scientific article

Difference in CXCR4 expression between sporadic and VHL-related hemangioblastoma

scientific article published on 26 February 2016

Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23.

scientific article published on 12 July 2015

Enhanced microglial pro-inflammatory response to lipopolysaccharide correlates with brain infiltration and blood-brain barrier dysregulation in a mouse model of telomere shortening.

scientific article published on 3 August 2015

EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion

scientific article

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

scientific article published on 30 June 2016

Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines

scientific article published on 23 October 2015

Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific.

scientific article published on 12 September 2016

Genotype-phenotype correlations in spastic paraplegia type 7: a study in a large Dutch cohort

scientific article published on 10 September 2012

Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma

scientific article published on 23 March 2015

Hierarchical Distribution of the Tau Cytoskeletal Pathology in the Thalamus of Alzheimer's Disease Patients.

scientific article

Huntington's disease (HD): degeneration of select nuclei, widespread occurrence of neuronal nuclear and axonal inclusions in the brainstem

scientific article

Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis

scientific article

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

scientific article published in March 2018

Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain

scientific article

Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: a report from EOR

scientific article

Kinome profiling in pediatric brain tumors as a new approach for target discovery

scientific article

MBRS-36. IDENTIFICATION OF TWO PROTEIN-SIGNALING STATES DELINEATING TRANSCRIPTIONALLY HETEROGENEOUS HUMAN MEDULLOBLASTOMA.

scientific article published on 22 June 2018

MEDU-07. THE DEVELOPMENTAL STAGE OF THE MEDULLOBLASTOMA CELL-OF-ORIGIN IS MAINTAINED IN CANCER AND RESTRICTS HEDGEHOG PATHWAY USAGE AND DRUG SENSITIVITY

scientific article published on 23 April 2019

MGMT-STP27 methylation status as predictive marker for response to PCV in anaplastic Oligodendrogliomas and Oligoastrocytomas. A report from EORTC study 26951.

scientific article published on 15 August 2013

Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.

scientific article published on 29 August 2013

Multiple VEGF family members are simultaneously expressed in ovarian cancer: a proposed model for bevacizumab resistance.

scientific article published on January 2012

Neonatal loss of motor function in human spina bifida aperta

scientific article published on 01 August 2004

Neurofibromatosis type 1 associated low grade gliomas: A comparison with sporadic low grade gliomas

scientific article

Neuropathological Diagnostic Considerations in Hyperkinetic Movement Disorders ⬇️

scientific article published on February 14, 2013

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease

scientific article published on 27 July 2015

Novel insights into vascularization patterns and angiogenic factors in glioblastoma subclasses

scientific article published on 15 September 2016

Optimizing targeted cancer therapy: towards clinical application of systems biology approaches

scientific article published on May 2012

Overexpression of cystathionine γ-lyase suppresses detrimental effects of spinocerebellar ataxia type 3.

scientific article

Pathogenesis of cerebral malformations in human fetuses with meningomyelocele

scientific article published on March 2008

Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology

scientific article published on 20 July 2015

Recruitment of bone marrow derived cells during anti-angiogenic therapy in GBM: the potential of combination strategies

scientific article

Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9

scientific article

Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons

scientific article published on 31 May 2016

Subclassification of newly diagnosed glioblastomas through an immunohistochemical approach.

scientific article

TGF-β Antibody Uptake in Recurrent High-Grade Glioma Imaged with 89Zr-Fresolimumab PET.

scientific article

TRAIL-receptor expression is an independent prognostic factor for survival in patients with a primary glioblastoma multiforme

scientific article published on 17 March 2006

The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice

scientific article

The brainstem pathologies of Parkinson's disease and dementia with Lewy bodies.

scientific article

Therapy-Resistant Complex Regional Pain Syndrome Type I: To Amputate or Not? ⬇️

scientific article published on October 5, 2011

Tumor vessel biology in pediatric intracranial ependymoma

scientific article published on April 2010

VEGF-PET imaging is a noninvasive biomarker showing differential changes in the tumor during sunitinib treatment

scientific article published on 17 November 2010

VEGF-SPECT with ¹¹¹In-bevacizumab in stage III/IV melanoma patients.

scientific article

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