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List of works by Freddy Heitz

A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation

scientific article

Correction: Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism.

scientific article published on 17 February 2011

Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors

scientific article published on 17 October 2011

Drug discovery and development for Huntington's disease - an orphan indication with high medical need.

scientific article published on September 2008

First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis ⬇️

scientific article published on November 11, 2010

Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity

scientific article

Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy

scientific article

Huntington's disease: from experimental results to interaction networks, patho-pathway construction and disease hypothesis

scientific article published in 2007

Inhibition of host NOX1 blocks tumor growth and enhances checkpoint inhibitor-based immunotherapy

scientific article published on 27 June 2019

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

scientific article published on 05 April 2013

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

scientific article published on 12 August 2017

NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors

scientific article published on 02 March 2020

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

scientific article

Presence of functional oxytocin receptors in cultured human myoblasts

scientific article published in March 2002

Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes.

scientific article

Small molecule drug discovery for Huntington's Disease

scientific article

Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism

scientific article (publication date: 7 February 2011)

Up-regulation of vasopressin and angiotensin II receptors in the thalamus and brainstem of inbred polydipsic mice

scientific article published in February 2002

siRNA screen identifies QPCT as a druggable target for Huntington's disease

scientific article

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