List of works - Diego O Croci

"Time sweet time": circadian characterization of galectin-1 null mice.

scientific article

A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease.

scientific article

Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway

scientific article published on 8 February 2008

Binding of galectin-1 to αIIbβ3 integrin triggers “outside-in” signals, stimulates platelet activation, and controls primary hemostasis

scientific article published on 27 March 2012

Cell-type specific regulation of galectin-3 expression by glucocorticoids in lung Clara cells and macrophages

scientific article published on 01 June 2011

Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities

scientific article published on 01 October 2020

Development of reformed ethanol fuel cell system for backup and off-grid applications — system design and integration

article

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

article

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

scientific article

Dissecting the pathophysiologic role of endogenous lectins: glycan-binding proteins with cytokine-like activity?

scientific article published on 22 February 2007

Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings

scientific article published on January 2010

Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment

scientific article published on 15 June 2007

Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: mechanisms and biomedical applications.

scientific article published on 04 February 2011

Fucans, but not fucomannoglucuronans, determine the biological activities of sulfated polysaccharides from Laminaria saccharina brown seaweed

scientific article

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer

scientific article published on January 2008

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

scientific article

Galectin-1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to anti-VEGF

scientific article

Galectins in hematological malignancies

scientific article published on 01 July 2013

Glyco-nano-oncology: Novel therapeutic opportunities by combining small and sweet

scientific article published on 4 February 2016

Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors

scientific article

Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression.

scientific article

Immune-Mediated and Hypoxia-Regulated Programs: Accomplices in Resistance to Anti-angiogenic Therapies.

scientific article

Integrating structure and function of tandem-repeat galectins ⬇️

scientific article published on January 1, 2012

Linking the structure and thermal stability of beta-galactoside-binding protein galectin-1 to ligand binding and dimerization equilibria

scientific article published on September 2010

Linking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis: Glycans make the difference

scientific article published on 25 June 2014

Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8.

scientific article published on 27 September 2010

Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate.

scientific article published on January 2010

Novel roles of galectin-1 in hepatocellular carcinoma cell adhesion, polarization, and in vivo tumor growth.

scientific article published on June 2011

Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1.

scientific article published in September 2011

Overcoming the hurdles of tumor immunity by targeting regulatory pathways in innate and adaptive immune cells.

scientific article published on January 2010

Regulated expression of galectin-3, a multifunctional glycan-binding protein, in haematopoietic and non-haematopoietic tissues

scientific article published on February 2011

Regulation of galectins by hypoxia and their relevance in angiogenesis: strategies and methods

scientific article

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer ⬇️

scientific article published on March 23, 2012

Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment

scientific article

Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway

scientific article published on 01 October 2008

Study of galectins in tumor immunity: strategies and methods

scientific article published on January 2015

Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease

scientific article published on 29 November 2012

Targeting galectin-1-induced angiogenesis mitigates the severity of endometriosis

scientific article published on 08 August 2014

The aggressiveness of murine lymphomas selected in vivo by growth rate correlates with galectin-1 expression and response to cyclophosphamide

scientific article published on 27 September 2011

The galectin-1-glycan axis controls sperm fertilizing capacity by regulating sperm motility and membrane hyperpolarization.

scientific article published in July 2015

The immunoregulatory glycan-binding protein galectin-1 triggers human platelet activation

scientific article published on 5 November 2007

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10.

scientific article

Translating the 'Sugar Code' into Immune and Vascular Signaling Programs

scientific article published on 13 December 2016

List of works by Diego O Croci

"Time sweet time": circadian characterization of galectin-1 null mice.

A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease.

Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway

Binding of galectin-1 to αIIbβ3 integrin triggers “outside-in” signals, stimulates platelet activation, and controls primary hemostasis

Cell-type specific regulation of galectin-3 expression by glucocorticoids in lung Clara cells and macrophages

Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities

Development of reformed ethanol fuel cell system for backup and off-grid applications — system design and integration

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

Dissecting the pathophysiologic role of endogenous lectins: glycan-binding proteins with cytokine-like activity?

Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings

Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment

Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: mechanisms and biomedical applications.

Fucans, but not fucomannoglucuronans, determine the biological activities of sulfated polysaccharides from Laminaria saccharina brown seaweed

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

Galectin-1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to anti-VEGF

Galectins in hematological malignancies

Glyco-nano-oncology: Novel therapeutic opportunities by combining small and sweet

Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors

Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression.

Immune-Mediated and Hypoxia-Regulated Programs: Accomplices in Resistance to Anti-angiogenic Therapies.

Integrating structure and function of tandem-repeat galectins ⬇️

Linking the structure and thermal stability of beta-galactoside-binding protein galectin-1 to ligand binding and dimerization equilibria

Linking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis: Glycans make the difference

Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8.

Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate.

Novel roles of galectin-1 in hepatocellular carcinoma cell adhesion, polarization, and in vivo tumor growth.

Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1.

Overcoming the hurdles of tumor immunity by targeting regulatory pathways in innate and adaptive immune cells.

Regulated expression of galectin-3, a multifunctional glycan-binding protein, in haematopoietic and non-haematopoietic tissues

Regulation of galectins by hypoxia and their relevance in angiogenesis: strategies and methods

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer ⬇️

Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment

Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway

Study of galectins in tumor immunity: strategies and methods

Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease

Targeting galectin-1-induced angiogenesis mitigates the severity of endometriosis

The aggressiveness of murine lymphomas selected in vivo by growth rate correlates with galectin-1 expression and response to cyclophosphamide

The galectin-1-glycan axis controls sperm fertilizing capacity by regulating sperm motility and membrane hyperpolarization.

The immunoregulatory glycan-binding protein galectin-1 triggers human platelet activation

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10.

Translating the 'Sugar Code' into Immune and Vascular Signaling Programs