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List of works by Jan Sjölin

A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6

scientific article published on 21 February 2019

Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco® LPS Adsorber: study protocol for a double-blinded, randomized placebo-controlled trial

scientific article published on 08 December 2016

Adult bacterial meningitis: earlier treatment and improved outcome following guideline revision promoting prompt lumbar puncture

scientific article published on 5 February 2015

Anti-inflammatory effects of the antibiotics ceftazidime and tobramycin in porcine endotoxin shock: are they really anti-inflammatory? Authors' response

scientific article

Bacterial phenotype variants in group B streptococcal toxic shock syndrome

scientific article published on February 2009

Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model

scientific article

Cerebrospinal fluid shunt infections in children over a 13-year period: anaerobic cultures and comparison of clinical signs of infection with Propionibacterium acnes and with other bacteria

scientific article published in May 2008

Characterization of the inhibitory effect of voriconazole on the fungicidal activity of amphotericin B against Candida albicans in an in vitro kinetic model

scientific article published on 12 April 2008

Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study

scientific article published on 13 June 2014

Counteraction of early circulatory derangement by administration of low dose steroid treatment at the onset of established endotoxemic shock is not directly mediated by TNF-α and IL-6.

scientific article published on 15 June 2012

Differences in organ dysfunction in endotoxin-tolerant pigs under intensive care exposed to a second hit of endotoxin

scientific article published in May 2012

Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model

scientific article published on 27 March 2018

Early endotoxin-mediated haemostatic and inflammatory responses in the clopidogrel-treated pig.

scientific article published in November 2005

Early lumbar puncture in adult bacterial meningitis--rationale for revised guidelines

scientific article published on July 2013

Effect of a single dose of tobramycin on systemic inflammatory response-induced acute kidney injury in a 6-hour porcine model

scientific article published in October 2009

Effects of tigecycline and doxycycline on inflammation and hemodynamics in porcine endotoxemia: a prospective, randomized, and placebo-controlled trial

scientific article published on June 2015

Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in porcine endotoxin shock

scientific article

Endotoxin tolerance variation over 24 h during porcine endotoxemia: association with changes in circulation and organ dysfunction

scientific article

Evaluating the effects of protective ventilation on organ-specific cytokine production in porcine experimental postoperative sepsis

scientific article published on 10 May 2015

Expression of the C5a receptor (CD88) on granulocytes and monocytes in patients with severe sepsis

scientific article

Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime

scientific article published on 24 March 2020

F2-isoprostane, inflammation, cardiac function and oxygenation in the endotoxaemic pig.

scientific article published in March 2008

Induction of gliotoxin secretion in Aspergillus fumigatus by bacteria-associated molecules

scientific article

Inflammatory and circulatory effects of the reduction of endotoxin concentration in established porcine endotoxemic shock--a model of endotoxin elimination

scientific article published in March 2009

Inflammatory, coagulatory and circulatory responses to logarithmic increases in the endotoxin dose in the anaesthetised pig.

scientific article published in January 2006

Initial levels of organ failure, microbial findings and mortality in intensive care-treated primary, secondary and tertiary sepsis.

scientific article published on September 2015

Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial

scientific article published on 17 July 2003

Lower response to early T-cell-dependent vaccination after neurotrauma or neurosurgery in adults

scientific article published on 3 January 2015

Lumbar puncture in adult bacterial meningitis: time to reconsider guidelines?

scientific article published on 30 January 2013

Lumbar puncture performed promptly or after neuroimaging in adult bacterial meningitis: A prospective national cohort study evaluating different guidelines

scientific article published on 9 September 2017

Lung protective ventilation induces immunotolerance and nitric oxide metabolites in porcine experimental postoperative sepsis

scientific article

Meropenem versus Cefotaxime and Ampicillin as Empirical Antibiotic Treatment in Adult Bacterial Meningitis: a Quality Registry Study, 2008 to 2016

scientific article published on 22 October 2019

Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model

scientific article published on 14 November 2020

New automated method for determining postantifungal effect of amphotericin B against Candida species: effects of concentration, exposure time, and area under the curve

scientific article

Pneumococcal polysaccharide vaccination administered early after neurotrauma or neurosurgery

scientific article published on 6 January 2017

Posaconazole in Human Serum: a Greater Pharmacodynamic Effect than Predicted by the Non-Protein-Bound Serum Concentration ⬇️

scientific article published on April 18, 2011

Post-antifungal effect of amphotericin B and voriconazole against Aspergillus fumigatus analysed by an automated method based on fungal CO2 production: dependence on exposure time and drug concentration

scientific article published on 7 October 2004

Post-antifungal effect of amphotericin B and voriconazole against germinated Aspergillus fumigatus conidia

scientific article published on 26 March 2008

Protective ventilation reduces Pseudomonas aeruginosa growth in lung tissue in a porcine pneumonia model

scientific article

Rapid Bolus Administration Does not Increase The Extravasation Rate of Albumin: A Randomized Controlled Trial in The Endotoxemic Pig.

scientific article published on 5 October 2016

Rational use of aminoglycosides--review and recommendations by the Swedish Reference Group for Antibiotics (SRGA).

scientific article published on 28 December 2012

Release of SpeA from Streptococcus pyogenes after exposure to penicillin: dependency on dose and inhibition by clindamycin

scientific article published on 01 January 2006

Reply to Arends and Harkisoen

scientific article published on 13 October 2014

Sepsis--the unknown public disease of our time

scientific article published on 17 November 2015

Severe sepsis and septic shock require immediate care

scientific article published on February 9, 2011

The brain is a source of S100B increase during endotoxemia in the pig.

scientific article published on 6 November 2009

The impact of the systemic inflammatory response on hepatic bacterial elimination in experimental abdominal sepsis

scientific article published on 27 August 2019

Treatment of cerebrospinal fluid shunt infections in children using systemic and intraventricular antibiotic therapy in combination with externalization of the ventricular catheter: efficacy in 34 consecutively treated infections

scientific article published in September 2007

Variation in the propensity to release endotoxin after cefuroxime exposure in different gram-negative bacteria: uniform and dose-dependent reduction by the addition of tobramycin

scientific article published in January 2003

Voriconazole-induced inhibition of the fungicidal activity of amphotericin B in Candida strains with reduced susceptibility to voriconazole: an effect not predicted by the MIC value alone

scientific article published on 31 January 2011

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