List of works - Helmut Remschmidt

Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans

scientific article (publication date: April 1999)

Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia

scientific article

Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder

scientific article published in December 2007

Hyperactivity in patients with anorexia nervosa and in semistarved rats: evidence for a pivotal role of hypoleptinemia

scientific article (publication date: June 2003)

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity

scientific article

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/hyperactivity disorder

scientific article

Evidence for linkage of spelling disability to chromosome 15

scientific article

Neurophysiological correlates of relatively enhanced local visual search in autistic adolescents

scientific article published on 18 January 2007

Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations

scientific article

Auditory processing and dyslexia: evidence for a specific speech processing deficit

scientific article published in January 1998

Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration

scientific article published in July 1997

Evidence for the involvement of genetic variation in the oxytocin receptor gene (OXTR) in the etiology of autistic disorders on high-functioning level

scientific article

Mutation screen of the brain derived neurotrophic factor gene (BDNF): Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder

article

Association between an agouti-related protein gene polymorphism and anorexia nervosa

scientific article

Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations

scientific article published in April 2005

Antipsychotic-induced body weight gain: predictors and a systematic categorization of the long-term weight course

scientific article

A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs

scientific article

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder

scientific article

Dysfunctions in brain networks supporting empathy: an fMRI study in adults with autism spectrum disorders

scientific article

Prediction of low body weight at long-term follow-up in acute anorexia nervosa by low body weight at referral

scientific article

Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene

scientific article

First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children

scientific article published on 29 September 2009

Low leptin levels predict amenorrhea in underweight and eating disordered females

scientific article

Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?

scientific article

Atypical brain responses to reward cues in autism as revealed by event-related potentials

scientific article

Human dopamine D4 receptor gene: frequent occurrence of a null allele and observation of homozygosity

scientific article published in December 1994

Neural mechanisms of empathy in adolescents with autism spectrum disorder and their fathers

scientific article published on 30 July 2009

Prospective 10-year follow-up in adolescent anorexia nervosa--course, outcome, psychiatric comorbidity, and psychosocial adaptation

scientific article published in July 2001

Long-term course of adolescent schizophrenia

scientific article published on 16 February 2005

Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa

scientific article published in January 1997

Systematic mutation screening of the estrogen receptor beta gene in probands of different weight extremes: identification of several genetic variants

scientific article published in December 1998

Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals

scientific article

Ghrelin receptor gene: identification of several sequence variants in extremely obese children and adolescents, healthy normal-weight and underweight students, and children with short normal stature

scientific article

Further evidence for DYX1C1 as a susceptibility factor for dyslexia

scientific article

Body weight gain induced by atypical antipsychotics: an extension of the monozygotic twin and sib pair study

scientific article published in April 2010

Association and linkage of allelic variants of the dopamine transporter gene in ADHD.

scientific article

Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample

scientific article published in December 2008

Spectrum of binge eating symptomatology in patients treated with clozapine and olanzapine

scientific article published on January 2003

Systematic screening for mutations in the promoter and the coding region of the 5-HT1A gene

article

Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes

scientific article published in October 1998

Forty-two-years later: the outcome of childhood-onset schizophrenia

scientific article published on 10 August 2006

Clozapine-induced weight gain: a study in monozygotic twins and same-sex sib pairs

scientific article published in December 2005

Long-term outcome and prognosis of obsessive-compulsive disorder with onset in childhood or adolescence

scientific article published in March 2001

Ghrelin gene: identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students

scientific article published in June 2002

Genome scan for childhood and adolescent obesity in German families

scientific article published in February 2003

White blood cells and cortisol after sleep deprivation and recovery sleep in humans

scientific article published in January 2000

Coherent motion processing in autism spectrum disorder (ASD): an fMRI study

scientific article

5-HT2A promoter polymorphism -1438G/A in children and adolescents with obsessive-compulsive disorders

scientific article published in January 2002

Familial aggregation of spelling disability

scientific article published in October 1996

Clozapine: weight gain in a pair of monozygotic twins concordant for schizophrenia and mild mental retardation

scientific article published in February 2005

List of works by Helmut Remschmidt

Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans

Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia

Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder

Hyperactivity in patients with anorexia nervosa and in semistarved rats: evidence for a pivotal role of hypoleptinemia

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/hyperactivity disorder

Evidence for linkage of spelling disability to chromosome 15

Neurophysiological correlates of relatively enhanced local visual search in autistic adolescents

Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations

Auditory processing and dyslexia: evidence for a specific speech processing deficit

Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration

Evidence for the involvement of genetic variation in the oxytocin receptor gene (OXTR) in the etiology of autistic disorders on high-functioning level

Mutation screen of the brain derived neurotrophic factor gene (BDNF): Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder

Association between an agouti-related protein gene polymorphism and anorexia nervosa

Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations

Antipsychotic-induced body weight gain: predictors and a systematic categorization of the long-term weight course

A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder

Dysfunctions in brain networks supporting empathy: an fMRI study in adults with autism spectrum disorders

Prediction of low body weight at long-term follow-up in acute anorexia nervosa by low body weight at referral

Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene

First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children

Low leptin levels predict amenorrhea in underweight and eating disordered females

Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?

Atypical brain responses to reward cues in autism as revealed by event-related potentials

Human dopamine D4 receptor gene: frequent occurrence of a null allele and observation of homozygosity

Neural mechanisms of empathy in adolescents with autism spectrum disorder and their fathers

Prospective 10-year follow-up in adolescent anorexia nervosa--course, outcome, psychiatric comorbidity, and psychosocial adaptation

Long-term course of adolescent schizophrenia

Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa

Systematic mutation screening of the estrogen receptor beta gene in probands of different weight extremes: identification of several genetic variants

Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals

Ghrelin receptor gene: identification of several sequence variants in extremely obese children and adolescents, healthy normal-weight and underweight students, and children with short normal stature

Further evidence for DYX1C1 as a susceptibility factor for dyslexia

Body weight gain induced by atypical antipsychotics: an extension of the monozygotic twin and sib pair study

Association and linkage of allelic variants of the dopamine transporter gene in ADHD.

Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample

Spectrum of binge eating symptomatology in patients treated with clozapine and olanzapine

Systematic screening for mutations in the promoter and the coding region of the 5-HT1A gene

Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes

Forty-two-years later: the outcome of childhood-onset schizophrenia

Clozapine-induced weight gain: a study in monozygotic twins and same-sex sib pairs

Long-term outcome and prognosis of obsessive-compulsive disorder with onset in childhood or adolescence

Ghrelin gene: identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students

Genome scan for childhood and adolescent obesity in German families

White blood cells and cortisol after sleep deprivation and recovery sleep in humans

Coherent motion processing in autism spectrum disorder (ASD): an fMRI study

5-HT2A promoter polymorphism -1438G/A in children and adolescents with obsessive-compulsive disorders

Familial aggregation of spelling disability

Clozapine: weight gain in a pair of monozygotic twins concordant for schizophrenia and mild mental retardation