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List of works by Sanjive Qazi

A PREVIOUSLY UNKNOWN UNIQUE CHALLENGE FOR INHIBITORS OF SYK ATP-BINDING SITE: ROLE OF SYK AS A CELL CYCLE CHECKPOINT REGULATOR

scientific article

A novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N′-[2-(2-thiophene)ethyl]-N′-[2-(5-bromopyridyl)] thiourea]) ⬇️

scientific article published on February 1, 2012

A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies

scientific article

Absence of Genomic Ikaros/IKZF1 Deletions in Pediatric B-Precursor Acute Lymphoblastic Leukemia

scientific article published on July 2013

Anti-breast cancer activity of LFM-A13, a potent inhibitor of Polo-like kinase (PLK).

scientific article published on 26 October 2006

Anti-cancer activity profile of 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] (Compound 003), a novel nucleoside analog.

scientific article

Anti-inflammatory activity profile of JANEX-1 in preclinical animal models

scientific article published on 24 October 2007

Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study

scientific article published in January 2007

Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity ⬇️

scientific article published on September 10, 2010

CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells

scientific article

CD22 EXON 12 deletion as a pathogenic mechanism of human B-precursor leukemia ⬇️

scientific article published on September 14, 2010

CD22 Exon 12 deletion is a characteristic genetic defect of therapy‐refractory clones in paediatric acute lymphoblastic leukaemia ⬇️

scientific article published on October 21, 2011

CD22ΔE12 as a molecular target for RNAi therapy

scientific article published on 6 February 2015

CD22ΔE12 as a molecular target for corrective repair using RNA trans-splicing: anti-leukemic activity of a rationally designed RNA trans-splicing molecule

scientific article

Clinical activity of folinic acid in patients with chronic fatigue syndrome

scientific article published on 01 January 2006

Constitutive function of the Ikaros transcription factor in primary leukemia cells from pediatric newly diagnosed high-risk and relapsed B-precursor ALL patients

scientific article

Contemporary patient-tailored treatment strategies against high risk and relapsed or refractory multiple myeloma

scientific article published on 10 December 2018

Development of Polypeptide-based Nanoparticles for Non-viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL.

scientific article

Evaluating dissolution profiles of an anti-HIV agent using ANOVA and non-linear regression models in JMP software

scientific article

Gene expression profiles of infant acute lymphoblastic leukaemia and its prognostically distinct subsets

scientific article published on 4 April 2010

Improved oral bioavailability of anti-HIV agent N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (HI-443) in a novel lipophilic formulation

scientific article published on 01 January 2007

In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates

scientific article published in January 2004

In vitro and in vivo chemosensitizing activity of LFM-A13, a dual-function inhibitor of Bruton's tyrosine kinase and polo-like kinases, against human leukemic B-cell precursors

scientific article published on January 2011

In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs

scientific article published in January 2005

In vivo antiretroviral activity of stampidine in chronically feline immunodeficiency virus-infected cats

scientific article

In vivo pharmacokinetics and toxicity of a novel hydrophilic oral formulation of the potent non-nucleoside reverse transcriptase inhibitor compound N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (HI-443)

scientific article published on 01 January 2007

In vivo toxicity, pharmacokinetics, and anti-human immunodeficiency virus activity of stavudine-5'-(p-bromophenyl methoxyalaninyl phosphate) (stampidine) in mice

scientific article

Incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia

scientific article published on December 2013

Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network

scientific article published on 25 April 2011

Inhibition of mast cell leukotriene release by thiourea derivatives

scientific article

Intronic CD22 Gene Mutations as A Pathogenic Mechanism of Human B-Precursor Leukemia ⬇️

scholarly article

JAK3 pathway is constitutively active in B-lineage acute lymphoblastic leukemia ⬇️

scientific article published on November 11, 2010

KU HAPLOINSUFFIENCY CAUSES A LYMPHOPROLIFERATIVE DISORDER OF IMMATURE T-CELL PRECURSORS DUE TO IKAROS MALFUNCTION.

scientific article published on June 2013

Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice

scientific article

Low Dose Total Body Irradiation Combined With Recombinant CD19-Ligand × Soluble TRAIL Fusion Protein is Highly Effective Against Radiation-Resistant B-Precursor Acute Lymphoblastic Leukemia in Mice

scientific article published on April 2015

Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia ⬇️

scientific article published on April 8, 2013

Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus

scientific article published in March 2004

Polo-like-kinase 1 (PLK1) as a molecular target to overcome SYK-mediated resistance of B-lineage acute lymphoblastic leukaemia cells to oxidative stress

scientific article

Potency of stampidine against multi-nucleoside reverse transcriptase inhibitor resistant human immunodeficiency viruses

scientific article published on 01 February 2006

Prevention of DMBA-induced mammary gland tumors in mice by a dual-function inhibitor of JAK3 and EGF receptor tyrosine kinases

scientific article published on 02 March 2020

Prevention of UVB-induced skin inflammation, genotoxicity, and photocarcinogenesis in mice by WHI-P131, a dual-function inhibitor of Janus kinase 3 and EGF receptor kinase

scientific article published in January 2010

Rational design of an immunoconjugate for selective knock-down of leukemia-specific E2A-PBX1 fusion gene expression in human Pre-B leukemia

scientific article

Recombinant human CD19L-sTRAIL effectively targets B cell precursor acute lymphoblastic leukemia

scientific article

Recombinant human CD19‐ligand protein as a potent anti‐leukaemic agent ⬇️

scientific article published on February 17, 2011

Regulatory phosphorylation of Ikaros by Bruton's tyrosine kinase

scientific article (publication date: 2013)

STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress

scientific article

SYK as a New Therapeutic Target in B-Cell Precursor Acute Lymphoblastic Leukemia

scientific article

Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros ⬇️

scientific article published on October 15, 2012

Site-specific enzymatic activation of the anti-HIV agent stampidine

scientific article published on 01 February 2006

Spleen tyrosine kinase as a molecular target for treatment of leukemias and lymphomas ⬇️

scientific article published on September 1, 2010

Stampidine as a promising antiretroviral drug candidate for pre-exposure prophylaxis against sexually transmitted HIV/AIDS ⬇️

scientific article published on February 24, 2012

Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations

scientific article published on November 2002

Structural requirements for potent anti-human immunodeficiency virus (HIV) and sperm-immobilizing activities of cyclohexenyl thiourea and urea non-nucleoside inhibitors of HIV-1 reverse transcriptase.

scientific article

Synthesis, separation and anti-HIV activity of distereoisomers of N-[p-(4-bromophenyl) -2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester (stampidine).

scientific article published in February 2006

Targeting Human B-Precursor Acute Lymphoblastic Leukemia Cells with Recombinant Human CD19 Ligand ⬇️

scholarly article

Targeting SYK kinase-dependent anti-apoptotic resistance pathway in B-lineage acute lymphoblastic leukaemia (ALL) cells with a potent SYK inhibitory pentapeptide mimic

scientific article published on 11 February 2010

Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles

scientific article published on January 2015

Therapeutic nanoparticle constructs of a JAK3 tyrosine kinase inhibitor against human B-lineage ALL cells

scientific article published on 01 January 2010

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